Ailuropoda melanoleuca (giant panda): 100463930
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Entry
100463930 CDS
T01329
Symbol
TOP2A
Name
(RefSeq) DNA topoisomerase 2-alpha isoform X1
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
aml
Ailuropoda melanoleuca (giant panda)
Pathway
aml01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
aml00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
100463930 (TOP2A)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
aml03032
]
100463930 (TOP2A)
03036 Chromosome and associated proteins [BR:
aml03036
]
100463930 (TOP2A)
Enzymes [BR:
aml01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
100463930 (TOP2A)
DNA replication proteins [BR:
aml03032
]
Eukaryotic type
DNA Topoisomerases
100463930 (TOP2A)
Chromosome and associated proteins [BR:
aml03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
100463930 (TOP2A)
Centrosome formation proteins
Centriole proteins
100463930 (TOP2A)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
HATPase_c
Toprim
Microp_apicomplexa_20
Motif
Other DBs
NCBI-GeneID:
100463930
NCBI-ProteinID:
XP_002924981
Ensembl:
ENSAMEG00000007989
UniProt:
G1LN78
LinkDB
All DBs
Position
13:complement(24693558..24721621)
Genome browser
AA seq
1533 aa
AA seq
DB search
MEVSPLQPVNENMQISKTKKNEDAKKGLSIERIYQKKTQLEHILLRPDTYIGSVELVTQQ
MWVYDEDIGINYREVTFVPGLYKIFDEILVNAADNKQRDPNMSCIRVTIDPENNLISIWN
NGKGIPVVEHKVEKMYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVE
TASREYKKMFKQTWMDNMGRAGEMELKPFNGEDYTCITFQPDLSKFKMQSLDKDIVALMV
RRAYDIAGSTKDVKVFLNGNKLPVKGFRSYVDMYLKDKVDETGNPLKIIHEQVNPRWEVC
LTMSEKGFQQISFVNSIATSKGGRHVDYVADQIVTKLVDVVKKKNKGGVAVKAHQVKNHM
WIFVNALIENPTFDSQTKENMTLQVKSFGSTCQLSEKFIKAAIGCGIVESILNWVKFKAQ
VQLNKKCSAVKHNRIKGIPKLDDANDAGGRNSNECTLILTEGDSAKTLAVSGLGVVGRDK
YGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKTLRYGKIMIMT
DQDQDGSHIKGLLINFIHHNWPSLLRHRFLEEFITPIVKVSKNKQEMAFYSLPEFEEWKS
STPNHKKWKVKYYKGLGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAISLAFSKKQIDD
RKEWLTHFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNSDNERSIPSMVD
GLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNN
LNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPKDDHTLKFLYDDNQRVEPEW
YIPIIPMVLINGAEGIGTGWSCKIPNFDIREVVNNIRRLMDGEEPLPMLPSYKNFKGTIE
ELAPNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGTEKTPPLITDYREY
HTDTTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHVGCLKKYDTVLDILR
DFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIENKPKKELIKVLIQR
GYDSDPVKAWKEAQQKVPDEEENEESDNENEAEKSDSVRDSGPTFNYLLDMPLWYLTKEK
KDELCKLRNEKEQELETLKRKSPSDLWKEDLAAFIEELEAVETKEKQEEQIGLPGKGGKA
KGKKTQMAEVLPSPCGKRVIPRVTIEMKAEAEKKIKKKIKNENTEGSPPEDGIELEGLKQ
RLEKKQKREAGTKTKKQTTLPFKPIKKGKKRNPWSDSESDMSSNESNFDVPPRETEPRRA
ATKTKFTVDLDSDDDFSDFDEKTQDKDFVPSDGSPLKTKASPKQTTKELKPQKSATSVMD
LDADETKDSVPLPPGSPAADFSAETEIINPVSKKKVAVKKIAAKSQSSTATTGAKKRAAP
KGSKKDPGLNSDVPQKPDPPKTKTRRKRKPSTSDDSDSNFEKMISKTVTNKKSKGESEDF
HLDLDSAVAPRAKSGRAKKPIKYLEESDEDDLF
NT seq
4602 nt
NT seq
+upstream
nt +downstream
nt
atggaggtgtcaccattgcagcctgtaaatgaaaatatgcaaatcagcaaaacaaagaaa
aatgaagatgctaagaaaggactgtctattgaaagaatctatcaaaagaaaacccaactg
gaacatatcttgctccgcccagacacctacattggctctgtggaactagtgacccagcaa
atgtgggtttatgatgaagatattggcattaactatagggaagtcacctttgtccctggg
ttgtacaaaatctttgatgagattctagtcaatgctgcagacaataaacaaagggaccca
aatatgtcttgtattagagtcacaattgacccggagaacaatttaattagcatatggaat
aatgggaaaggtattcctgttgttgaacacaaagttgagaagatgtatgtcccagctctc
atctttggacagctcctaacttctagtaactatgatgatgatgaaaagaaagtaacaggt
ggtcgaaatggctatggggccaaattgtgtaacatattcagtaccaaatttactgtggaa
acagcaagtagagaatacaagaaaatgttcaaacagacatggatggataacatggggaga
gctggtgagatggaactcaagccctttaatggggaagattatacatgcattactttccag
cctgacttgtccaagtttaaaatgcaaagcctagataaagatatcgttgcactgatggtt
agaagagcttatgatattgctggatccactaaagatgtcaaagtctttctcaatggaaat
aagctgccagtaaaaggattccgtagctatgtagatatgtatttgaaggataaggtagat
gaaactggcaatccactgaaaattatccatgaacaagtaaaccccaggtgggaagtatgt
ctaacaatgagtgaaaaaggctttcagcaaattagcttcgtcaacagcatcgctacttcc
aagggtggcagacatgttgattatgtagctgatcagattgtgactaaacttgttgatgtt
gtgaagaagaagaacaagggtggtgttgcagtaaaagcacatcaggtgaaaaatcacatg
tggatttttgtgaatgccttaattgaaaacccaacctttgactctcagacaaaagaaaac
atgaccttacaagtcaagagctttggatcaacatgccaattaagtgaaaaattcatcaaa
gctgcaattggctgtggtattgtggaaagcatactaaactgggtgaagtttaaggcccaa
gtccaattaaataaaaagtgttcagctgtaaaacataacagaatcaagggaattcccaaa
ctcgatgatgccaatgatgcagggggtcgaaactccaatgagtgtacactcatcctgact
gaaggagactcagctaaaactttggctgtttcaggccttggtgtggttgggagagacaaa
tacggtgttttcccacttagaggaaaaatactcaatgttcgagaagcttctcataaacag
atcatggaaaatgccgaaattaacaatatcatcaagattgtgggtcttcagtacaagaaa
aactatgaagatgaagattcattgaagactcttcgttatggaaagataatgattatgaca
gatcaggaccaagatggttcccatatcaaaggcctgctgattaattttatccatcacaac
tggccctctcttctacggcatcgttttctggaagagtttatcactcccattgtaaaggtg
tctaaaaacaaacaagaaatggcattctatagccttcctgaatttgaagaatggaagagt
tctactccaaatcataaaaaatggaaagtcaagtactacaaaggtttgggcaccagcaca
tcaaaagaagctaaagaatactttgcagatatgaaaagacatcgtattcaattcaaatat
tctggtcctgaagatgatgctgccatcagcctggcctttagcaagaaacagatagatgat
cgaaaggaatggttaactcatttcatggaggatagaaggcaacggaagttacttggcctt
cctgaggattacttgtatgggcaaactaccacatacctgacatataatgacttcataaat
aaggaacttatcctgttctcaaattctgataatgagagatctatcccatctatggtggat
ggtttgaaaccaggtcaaagaaaggttttgtttacctgtttcaaacggaatgataagcga
gaggtgaaggttgcccagttagctgggtcagtggctgagatgtcctcttatcatcatggt
gagatgtcactaatgatgaccattatcaatttggctcagaattttgtgggtagcaataat
ctgaacctcttgcagcccattggtcagtttggtactaggctgcatggtggcaaggattct
gctagtcctcgatacatcttcacaatgctcagccctttggctcggttgttatttccacca
aaagatgatcacacattaaagtttttatatgatgacaatcaacgtgttgaacctgaatgg
tacattcctattatacccatggtgctgataaatggtgctgaaggaatcggtactgggtgg
tcctgcaaaatccccaactttgatattcgtgaagttgtaaataatatcaggcgtttgatg
gatggagaagaacctttgccaatgcttccaagttacaagaacttcaagggtactattgaa
gagctggctccaaatcaatatgtgataagtggtgaagtggctattcttaattccacaacc
attgaaatctcagagcttcctatcagaacatggacccagacatataaagaacaggttcta
gagcccatgttgaacggaactgagaagacaccacctctcataacagattatagggaatac
catacagacaccactgtgaagtttgttgtgaaaatgactgaagagaaactggcagaggca
gagagagtgggactacacaaagtcttcaaactccaaactagccttacatgcaactctatg
gtgctttttgaccatgtaggatgtttaaagaaatatgacacagtgttggatattctaaga
gacttctttgaactcaggcttaaatattatggattaagaaaagaatggcttctaggaatg
cttggtgctgaatctgctaaactgaacaaccaggctcgctttatcttagagaaaatagat
ggcaaaataatcattgaaaataagcctaagaaagaattaattaaagttctgattcagagg
ggatatgattcagatcccgtgaaggcttggaaagaagcccagcaaaaggtaccagatgaa
gaagagaatgaagagagtgacaatgaaaatgaagctgaaaagagtgactctgtaagagat
tctggaccaaccttcaactaccttcttgatatgcctctttggtatctcaccaaggagaag
aaagatgaactgtgcaaactgagaaatgaaaaagagcaagagctagaaacattaaagaga
aagagtccatcagatttgtggaaagaagacttggctgcttttattgaagagctggaggct
gttgaaacaaaggaaaaacaagaagaacaaataggacttcctgggaaaggcgggaaagca
aaggggaaaaaaacacaaatggctgaagttttgccttctccatgcgggaaaagagtcatc
ccccgagtgaccatagagatgaaagcagaggcggaaaagaaaattaaaaagaaaattaag
aatgaaaacactgaagggagccctccagaagacggtatcgaactagaaggtctgaaacaa
aggttggagaaaaaacagaaaagagaagcaggtaccaagacaaagaagcaaactacattg
ccatttaaaccaatcaaaaaaggaaagaagagaaacccctggtctgattcagaatcagat
atgagcagtaacgaaagtaactttgatgtccctcctcgagagacagagccacggagagca
gcaacaaaaaccaaattcacggtggatttggattcagatgacgatttctcagattttgat
gaaaaaactcaagataaggattttgtcccatcagatggtagtcctcttaagaccaaagct
tccccaaaacagactactaaagaactgaagccacagaaaagtgccacgtcagtaatggac
cttgatgctgatgagaccaaggacagtgtgccacttcctccaggttcccctgctgctgat
ttctcagctgaaactgaaattataaaccctgtttctaaaaagaaggtggcggtgaagaag
atagcagcaaaaagtcagtcttccaccgccactacaggtgccaaaaaaagggcggcacca
aaaggaagcaaaaaggatccaggcttgaattctgatgtgcctcaaaagcctgatcctccc
aaaaccaaaactcgccgcaaaaggaagccatccacttctgatgattctgactctaatttt
gagaaaatgatttctaaaacagtcacaaacaagaaatccaagggggagagtgaggacttc
catctggacttagactcagctgtggctcctcgggccaaatctggacgggcaaagaaacct
ataaagtacctcgaagaatcagatgaagatgatctgttctaa
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integrated database retrieval system
