KEGG   Ailuropoda melanoleuca (giant panda): 100464499
Entry
100464499         CDS       T01329                                 
Symbol
PPP1CA
Name
(RefSeq) serine/threonine-protein phosphatase PP1-alpha catalytic subunit
  KO
K06269  serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
Organism
aml  Ailuropoda melanoleuca (giant panda)
Pathway
aml03015  mRNA surveillance pathway
aml04022  cGMP-PKG signaling pathway
aml04024  cAMP signaling pathway
aml04114  Oocyte meiosis
aml04218  Cellular senescence
aml04261  Adrenergic signaling in cardiomyocytes
aml04270  Vascular smooth muscle contraction
aml04390  Hippo signaling pathway
aml04510  Focal adhesion
aml04611  Platelet activation
aml04720  Long-term potentiation
aml04728  Dopaminergic synapse
aml04750  Inflammatory mediator regulation of TRP channels
aml04810  Regulation of actin cytoskeleton
aml04910  Insulin signaling pathway
aml04921  Oxytocin signaling pathway
aml04931  Insulin resistance
aml05031  Amphetamine addiction
aml05034  Alcoholism
aml05168  Herpes simplex virus 1 infection
aml05205  Proteoglycans in cancer
aml05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:aml00001]
 09120 Genetic Information Processing
  09122 Translation
   03015 mRNA surveillance pathway
    100464499 (PPP1CA)
 09130 Environmental Information Processing
  09132 Signal transduction
   04390 Hippo signaling pathway
    100464499 (PPP1CA)
   04024 cAMP signaling pathway
    100464499 (PPP1CA)
   04022 cGMP-PKG signaling pathway
    100464499 (PPP1CA)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    100464499 (PPP1CA)
   04218 Cellular senescence
    100464499 (PPP1CA)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100464499 (PPP1CA)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    100464499 (PPP1CA)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    100464499 (PPP1CA)
  09152 Endocrine system
   04910 Insulin signaling pathway
    100464499 (PPP1CA)
   04921 Oxytocin signaling pathway
    100464499 (PPP1CA)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100464499 (PPP1CA)
   04270 Vascular smooth muscle contraction
    100464499 (PPP1CA)
  09156 Nervous system
   04728 Dopaminergic synapse
    100464499 (PPP1CA)
   04720 Long-term potentiation
    100464499 (PPP1CA)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100464499 (PPP1CA)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    100464499 (PPP1CA)
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    100464499 (PPP1CA)
  09165 Substance dependence
   05031 Amphetamine addiction
    100464499 (PPP1CA)
   05034 Alcoholism
    100464499 (PPP1CA)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    100464499 (PPP1CA)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    100464499 (PPP1CA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:aml01009]
    100464499 (PPP1CA)
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:aml03021]
    100464499 (PPP1CA)
   03019 Messenger RNA biogenesis [BR:aml03019]
    100464499 (PPP1CA)
   03041 Spliceosome [BR:aml03041]
    100464499 (PPP1CA)
Enzymes [BR:aml01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     100464499 (PPP1CA)
Protein phosphatases and associated proteins [BR:aml01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    Catalytic subunits
     100464499 (PPP1CA)
Transcription machinery [BR:aml03021]
 Eukaryotic type
  RNA polymerase II system
   Other transcription-related factors
    Transcription termination factor
     100464499 (PPP1CA)
Messenger RNA biogenesis [BR:aml03019]
 Eukaryotic type
  mRNA processing factors
   3' end processing
    Cleavage and polyadenylation specificity factor (CPSF) complex
     100464499 (PPP1CA)
Spliceosome [BR:aml03041]
 Other splicing related proteins
  Spliceosome associated proteins (SAPs)
   Other SAPs
    100464499 (PPP1CA)
SSDB
Motif
Pfam: Metallophos STPPase_N
Other DBs
NCBI-GeneID: 100464499
NCBI-ProteinID: XP_002921324
Ensembl: ENSAMEG00000000758
UniProt: G1L1P7
LinkDB
Position
16:complement(85860609..85863932)
AA seq 330 aa
MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLK
ICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL
LRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDL
QSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHD
LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAD
KNKGKYGQFSGLNPGGRPITPPRNSAKAKK
NT seq 993 nt   +upstreamnt  +downstreamnt
atgtccgacagcgagaagctcaacctggactctatcatcgggcgcctgctggaagtgcag
ggctcgcggcctggaaagaatgtacagctaacagagaacgagatccgtggtctgtgcctc
aaatcacgggagattttcctgagccagcccattcttctggaactggaggcacccctcaag
atctgcggtgacatccatggccagtactacgaccttctgcggctatttgagtatggcggc
ttccctccagagagcaactacctcttcctgggggactacgtggaccggggcaagcagtct
ttggagaccatctgcctgctgctggcctataagatcaagtaccctgagaacttcttcctg
ctccgtgggaaccacgaatgtgccagcatcaaccgcatctacggcttctatgatgagtgc
aagagacgctacaacattaaactgtggaaaacctttaccgactgcttcaactgcctgccc
attgctgccattgtggacgagaagatcttctgctgccacggaggcctgtccccagacttg
caatccatggagcagattcggcgtatcatgcggcccacagatgtgcctgaccagggcctg
ctgtgtgacctgctgtggtctgaccctgacaaggacgtgcagggctggggcgagaatgac
cgtggtgtctcctttacctttggggctgaggtagtggccaagttcctgcacaagcacgac
ttggacctcatctgccgggcgcaccaggtggtggaagatggctatgagttctttgccaag
cggcagctggtgacactgttctcggctcccaactactgtggcgagtttgacaacgcaggc
gccatgatgagtgtcgatgagacgctcatgtgctccttccagatcctcaagcccgctgac
aagaacaaggggaaatacgggcagttcagtggcctgaaccctggaggccggcccatcacc
ccaccccgcaactccgccaaagccaagaagtag

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