Ailuropoda melanoleuca (giant panda): 100464687 Help Entry 100464687         CDS       T01329                                  Symbol DNAH8 Name (RefSeq) dynein heavy chain 8, axonemal   KO K10408   dynein axonemal heavy chain Organism aml  Ailuropoda melanoleuca (giant panda) Pathway aml04814   Motor proteins aml05014   Amyotrophic lateral sclerosis aml05016   Huntington disease aml05022   Pathways of neurodegeneration - multiple diseases Brite KEGG Orthology (KO) [BR:aml00001]  09140 Cellular Processes   09142 Cell motility    04814 Motor proteins     100464687 (DNAH8)  09160 Human Diseases   09164 Neurodegenerative disease    05014 Amyotrophic lateral sclerosis     100464687 (DNAH8)    05016 Huntington disease     100464687 (DNAH8)    05022 Pathways of neurodegeneration - multiple diseases     100464687 (DNAH8)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    03037 Cilium and associated proteins [BR:aml03037]     100464687 (DNAH8)    04812 Cytoskeleton proteins [BR:aml04812]     100464687 (DNAH8) Cilium and associated proteins [BR:aml03037]  Motile cilia and associated proteins   Dynein arm    100464687 (DNAH8) Cytoskeleton proteins [BR:aml04812]  Eukaryotic cytoskeleton proteins   Microtubules    Tubulin-binding proteins     Dyneins      100464687 (DNAH8) SSDB OrthologParalogGFIT Motif Pfam:  DHC_N1 AAA_6 DHC_N2 Dynein_C AAA_8 AAA_9 AAA_7 AAA_lid_11 MT Dynein_heavy AAA_5 Dynein_AAA_lid AAA_lid_1 DYN_lid AAA_22 DYH2-5-8_CC AAA_16 Sigma54_activat MJ0013 Motif Other DBs NCBI-GeneID:  100464687 NCBI-ProteinID:  XP_034516545 Ensembl:  ENSAMEG00000024100 LinkDB All DBs Position 5:33327767..33659864 Genome browser AA seq 4493 aa AA seqDB search MMRLYIDNAAPEKLKGLCVFFVRCHNDIAINVKNIHEEVLFTVLDASTGILNGIRNMLSS VFLPAILATNNWGALNQSKQGESEKHIFTETINRYLSFLDGARVSIEGTVMLKKVDNIDF SKLHTFEEVTAAASNSETVRQLEDVLMTWYKQIEQVLIESEQMRKEADDSGPLTELEHWK RMSAKFNYIIEQIKGPTCKAVINVLNVAHSKLLKNWRELDARITDTANESKDNVRYLYTL EKVCQPLYNYDLVSMAHGIQNLINAIRMIHSVSRYYNTSERMTSLFIKVTNQMVTACKAY IIDGGTIHIWDQETPLVLKKIQDCIFLFKEYQTSFHKTRKQILESSGEKSFEVSEMYIFG KFEAFCKRLEKITEMITVVQTYSALSNSTIEGIDIMSIKFKNIYQGVKKKQYDILDPRRT EFDIDFSDFMTKINGLEIQIQAFMNSTFGKILSSQQALQLLQRFQKLQIPCLQSEINHTI ERILQCYVAELEATKKLYHSQKDDPPLARNMPPVAGKILWVRQLYRRISEPINYFFKNSE ILSSAEGKAVIRQYNKISYVLVEFEVVYHTAWVREVSQLQYALQATLFVRHPETGKLLVN FDPKILEVVRETKCMLKMKLDVPEQAKKLLKLESKLKADKLHLQGLLQYYDDLCQEVPSV FVNLMTPKMKKVESVLRQGLTILTWSSLTLESFFQEVDSVLDMFNQLLKKISDLCEMHID TVLKEIAKTLLISLPESGATKVEDMLVLNEMYTKEWADVLNHKSKHVEEAVKELISIFEN IYEVKHSGKTAKPLPEQRKHVVFGSETEEGESIDYEANMIPEVDVNDKEDEFKKECKEVY AFFSHQLLDSLQKATRLSLDTMKRRIFVSSHHGRRRSEDVISFIKTEVHLAIPNVVMIPS LDDIQQAINRMIQLTLEVSRGVAHWGQQQTRHVKTAVTSPSRTATDVTPVNTAKPAKKEE RSFEEIIPARKLKNFYPGVAEHKDISKLVLLLSSSVNSLQKVAHEALQDFQKYKTLWTED RDVKVKEFLGNNPSLTEIRSEILHFATFEQEIDELKPVIVVGALELHTEPMKLALSIEAK AWKMLLCRYLNEEYKKKMSDMIAFINEYLKKLSRPIRDLDDVRFAMEALSSIRDNEIQMD MTLGPIEEAYAILNRFEVEVTKEESEAVDTLRYSFNKLQSKAVSVQDELVQVQPKFKSSL LESVEVFREDVMNFAESYEMEGPMVPNIPPQEASNRLQIFQANFDDLWRKFVTYSSGEQL FGLPVTDYEVLHKTRKELNLLQKLYGLYDTVMNNISGYYEILWGDVDIEKINAELQEFQN RCRKLPKGLKDWQAFLDLKKRIDDFSESCPLLEMMTNKAMKQRHWDRISELTGTPFDVES DSFCLRNIMEAPLLKNKDDIEDICISAIKEKDIEAKLTQVIENWTNQNLSFAAFKGKGEL LLKGTESGEIITLMEDSLMVLGSLLSNRYNAPFKKTIQNWVYKLSTSSDIIEEWLVVQNL WVYLEAVFVGGDIAKQLPQEAKRFQNIDKSWIKIMQRAHENPNVISCCVGDETMGQLLPH LHEQLEVCQKSLTGYLEKKRLLFPRFFFVSDPVLLEILGQASDSHTIQPHLPAVSDNINE VTFHAKDYDRILAVISREGEKIILDSPVMAKGPVEIWLMDLLKTQMSSLHNIIRSAFYQI SDSGFQLLPFLNHFPAQVGLLGIQMLWTHDSEEALNNAKDDRKIMHVTNQKFLDILNTLI GQTTHDLSKFDRVKFETLITIHVHQRDIFDDLVKMHIKSVTDFEWLKQSRFYFKEDLDQT VVSITDVDFIYQNEFLGCTDRLVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTK DMGRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYI VLTARKERKKQFIFSDGDCVDLNPEFGIFLTMNPGYAGRQELPENLKIQFRTVAMMVPDR QIIMRVKLASCGFLENVILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGAQKRA RPEDSELSTVMRGLRDMNLSKLVDEDEPLFLSLINDLFPGLQLDSSTHAELQAAVANQVQ LEGLINHPPWNLKLVQLYETSLVRHGLMTLGPSGSGKTTVITILMKALTECGRPHREMRM NPKAITAPQMFGRLDTATNDWTDGIFSTLWRKTLKAKKGENIFLILDGPVDAIWIENLNS VLDDNKTLTLANGDRIPMAPSCKLLFEVHNIENASPATVSRMGMVYISSSALSWRAILQA WLKRRTAQEATVFLTLYDKIFEDTYTYMKLNLNPKMQLLECNYIMQSLNLLEGLIPSKEE GGVSCVEHLHKLFVFGLMWSLGALLELESREKLEAFLRNHESKLDLPEIPKGTSQTMYEF YVTDYGDWEHWNKKLQPYYYPTDSIPEYSSILVPNVDNVRTNFLIDTIAKQQKAVLLTGE QGTAKTVMVKAYLKKYDPEVQLSKSLNFSSATEPMMFQRTMESYVDKRMGSTYGPPGGRK MTVFIDDINMPVINEWGDQITNEIVRQMMEMEGMYSLDKPGDFTTIVDVQIIAAMIHPGG GRNDIPQRLKRQFTVFNCTLPSNASIDKIFGLIGCGYFDPCRKFKLEVCEMIANLVSAGR VLWQWTKVKMLPTPSKFHYIFNLRDLSRIWQGMLTIKAEECDSISVLLSLFKHECNRVIA DRFVTPEDEQWFNIHLVRAVEENINPDVTSYILPEPYFVDFLQEMPEPAGDEPEDTVFEV PKVYELVPSFDFLSEKLQFYQRQFNEIIRGTSLDLVFFKDAMTHLIKISRIIRTSCGNAL LVGVGGSGKQSLSRLASFIAGYQIFQITLTRSYNVNNLIEDLKGLYKVAGADGKGITFIF TDNEIKDEAFLEYLNNLLSSGEISNLFARDEMDEITQGLISVMKKELPRHPPTFDNLYEY FISRSRKNLHVVLCFSPVGEKFRARSLKFPGLISGCTMDWFSRWPKEALIAVASYFLSGY SIVCSSDTKRQVVETMGLFHDMVSESCENYFQRYRRRAHVTPKSYLSFINGYKSIYTEKV KHINEQAERMNIGLDKLMEASESVAKLSQDLTVKEKELAVASVKADEVLAEVTVSAQASA KVKNEVQEVKDKAQKIVDEIDSEKVKAETKLEAAKPALEEAEAALNTIKPNDIATVRKLA KPPHLIMRIMDCVLLLFQKKIDPVTMDPEKPCCKPSWGESLKLMSATGFLWSLQQFPKDT INEETVELLQPYFNMDDYSLENAKKVCGNVAGLLSWTLAMATFYGINREVLPLKANLAKQ EGRLAVANAELGKAQALLDEKQGELDKVQAKFDAAMSEKMDLLNDADMCRKKMQAASTLI DGLSGEKVRWTQQSKEFKAQINRLVGDILLCTGFLSYLGPFNQIFRNYLLKDQWEIELRA RKIPFTENLNLISMLVDPPTIGEWGLQGLPGDDLSIQNGIIVTKATRYPLLIDPQTQGKT WIKSKERENDLQVTSLNHKYFRTHLEDSLSLGRPLLIEDIREELDPALDNVLEKNFIKSG TTFKVKVGDKECDIMDTFKLYITTKLPNPAFTPEINAKTSVIDFTVTMKGLENQLLRRVI LTEKQELESERVKLLEDVTFNKQKMKELEDNLLYKLSATKGSLVDDESLIGVLRITKQTA TEVSEKLHVAAETEIKINTAQEEFRPAATRGSILYFLITEMSMVNIMYQTSLAQFLKLFD QSMARSEKSPLPQKRITNIIEYLTYEVFIYSVRGLYENHRFLFVLLLTLKIDLQRGTVKP REFQALIKGGAALDLKACPPKPFRWILDMTWLNLVELSKLPQFAEIMNQISRNEKGWKSW FDKDAPEEEIIPDGYNDSLDTCRKLLLIRSWCPDRTVFQARKYIADSLEDKYTEPVILNL EKTWEESDTRTPLICFLSMGSDPTIQIDALAKKLKLECRTISMGQGQEVHARKLIQMSMQ QGGWVLLQNCHLGLEFMEELLETLTTTEANADSFRVWITTEPHDRFPITLLQTSLKFTNE PPQGVRAGLKRTFAGINQDLLDISNLPMWKPMLYTVAFLHSTVQERRKFGPLGWNIPYEF NSADFAASVQFIQNHLDECDIKKGVSWSTVRYMIGEVQYGGRVTDDFDKRLLNCFARVWF SEKMFEPSFCFYTGYKIPLCKTLDQYFEYIQSLPSLDNPEVFGLHPNADITYQSNTASAV LETITNIQPKESGGGVGETREAIVYRLSEDMLSKLPPDYIPHEVKARLIKMGHLNSMNIF LRQEIDRMQKVISILRSSLSDLKLAIEGTIIMSENLRDALDNMYDARIPQIWKRVSWDSS TLGFWFTELLERNAQFSTWIFEGRPNVFWMTGFFNPQGFLTAMRQEVTRAHKGWALDSVT IHNEVLRQTKEEIASPPVEGVYIYGLYMDGAAWDRRNGKLTESTPKVLFTQLPVLHIFAV NSIAPKDPKLYVCPIYKKPRRTDLTFITVVYLRTVLSPDHWILRGVALLCDIK NT seq 13482 nt NT seq  +upstreamnt  +downstreamnt atgatgagattgtatatagacaatgcagccccggagaaactaaaaggattatgtgtattt tttgttcgctgtcacaatgatattgcgataaatgttaaaaatattcacgaggaagtgctc tttaccgtactggatgcatcaacaggaatactaaacgggattaggaatatgctgtcaagt gtatttctaccagctattcttgcaacaaataattggggtgccctaaaccagtccaagcaa ggagaatctgaaaaacacattttcactgaaaccatcaacagatacctttcatttttagat ggtgctagagtaagtatcgagggaacagttatgttaaagaaggtagacaacatcgatttt tccaagctgcatacgtttgaagaagtgactgctgcagctagcaactcagaaactgttcgt cagctggaggacgtgctgatgacatggtataaacagattgaacaggtacttattgagagt gagcagatgagaaaagaagctgatgactccggtccactcactgaattggaacactggaaa cgcatgtcagccaaattcaattacatcattgagcagattaaagggccaacttgtaaggct gtcataaatgtgcttaatgttgcacactccaaactgttgaagaattggcgtgagttggat gcaagaataacggatacagcaaatgaatcaaaagataatgtcagatatttgtacactcta gaaaaagtatgtcagcctctctataactatgacctagtttccatggcacatggaatacaa aatttgattaatgccatcagaatgattcacagtgtgtcacggtattataatacctcagag agaatgacctcattgtttattaaggtaacaaatcaaatggtgacggcatgtaaagcgtat attattgatggaggaaccatccacatatgggatcaggaaacaccactcgtattaaagaaa attcaggattgcatttttctattcaaggaatatcagacatcttttcataaaacaaggaag cagattttagaatcgtcaggggaaaaatcttttgaggtttcagaaatgtatatatttgga aaatttgaagctttctgcaaaagactggagaagattacagaaatgataactgttgtgcaa acatattcagccttgagtaattccaccatagagggaatagatattatgtcgataaaattc aaaaacatatatcaaggggttaagaaaaaacaatatgacattctggatccaagaaggaca gaatttgatatagatttctcagatttcatgacaaaaatcaatggcttagagatacaaata caagcatttatgaacagtacttttggaaaaatcttatcttctcagcaggcccttcagctt cttcaaagattccagaaactgcaaatcccttgtcttcagtcagaaataaaccatacaatt gagcgtattcttcagtgttatgtggctgaacttgaagctactaagaagctttatcattct caaaaagatgaccctcctcttgctcgcaacatgccccctgtagcaggaaaaatactttgg gtgaggcagctctatcgtcggataagcgaacccatcaactatttctttaaaaactcagaa attttgtcaagcgcggaaggtaaagctgttattcgtcagtataacaaaatttcctatgtt ctggtggaatttgaggtggtctatcacacagcctgggtcagagaggtctcgcagttacag tatgctttacaagccacgctttttgtgcgacacccagaaactgggaaattgctggttaat tttgatcccaaaattctagaagttgttcgggaaactaagtgcatgctaaaaatgaagctg gatgtaccagaacaggcaaagaaattgctaaaattggaaagtaaattgaaagcagacaaa ttgcatttgcagggtcttctgcaatattatgatgacttatgtcaggaagtgccttcggtg tttgtcaatctgatgacccctaaaatgaaaaaggtggaatctgtgttgagacaagggctc acaatattaacatggtcatctttaaccctggaaagcttctttcaagaagttgactcagtt ttggatatgttcaatcaacttttaaagaagatcagtgacttgtgtgaaatgcatattgat acagttctgaaggagatagccaaaactctgttaatttccctgcctgaaagtggtgctacc aaagtagaagatatgttggtgctcaatgagatgtacacaaaagaatgggctgatgttcta aaccacaaaagtaagcatgtggaagaagctgtcaaagaacttatatcaatatttgaaaat atttatgaagttaagcacagtgggaaaacagcaaaaccattaccagaacagaggaaacat gttgtttttggaagtgaaacagaagagggtgaaagcattgattatgaggctaatatgatt cctgaggttgatgttaatgataaagaagatgaatttaagaaggaatgtaaagaggtctat gcttttttctctcatcaattactagacagtcttcaaaaagctacccggttatctttggac acaatgaaaagaagaatatttgtttcaagccaccatggacgaaggcgatcagaagatgtt atttcctttataaaaactgaagtacatcttgcgattccgaatgtggtaatgattcctagt ttggatgacattcaacaagccatcaaccggatgatccagcttaccctggaggtcagcaga ggagtggctcactgggggcaacagcagacccgtcacgtcaagactgccgtcaccagtccc agccgtactgcaactgatgtgacccctgtaaacacagcaaaaccggctaagaaggaagag agatcttttgaagaaattattcctgcaaggaaactgaagaatttttatccaggggtagca gagcacaaggatatttccaagttggttctcctcctttcttcctctgtgaattctctacaa aaggtggctcacgaggccttgcaggacttccaaaagtacaagacgctctggaccgaggac cgagacgtgaaagtgaaggagttcttgggtaacaacccttctctgactgaaatcagatca gaaattctacactttgccacttttgaacaggagatcgatgagttgaagcctgttattgtt gtgggagcacttgaactgcatacagagccaatgaaattggccttatcaattgaggctaag gcatggaagatgttactctgtcgatacttgaatgaagaatacaaaaagaaaatgtcagac atgatcgcatttatcaatgaatacttgaaaaagttatctagacccattcgtgatttagat gatgtcaggtttgcaatggaagccttatcgtctatccgtgataatgaaattcaaatggac atgactttgggaccaattgaagaagcctatgctattttaaacagatttgaagttgaagta accaaagaagaatcagaagcagtcgataccttgagatattctttcaacaaactgcagagc aaagctgtttctgtgcaagatgaactagttcaagtgcagccgaagtttaaaagtagtctt cttgagtctgtggaagtttttcgtgaggatgtaatgaacttcgcagaatcatatgagatg gaaggaccgatggttccaaatattccaccccaagaagctagtaacaggctacagattttt caggctaattttgatgatctgtggaggaagtttgttacatattcatctggtgaacaactt tttggattgcctgtgactgattatgaggttttacacaaaactagaaaagagctcaacttg ctgcagaagctgtatggactgtatgatactgtaatgaacaatattagtggttattatgaa atactttggggagatgtagacattgaaaaaattaatgcagaactgcaggaatttcagaac aggtgtcgtaaactcccaaaagggcttaaagattggcaagcttttttggatctgaaaaaa agaattgatgatttcagtgagtcatgtcctctgctggaaatgatgaccaataaggcaatg aaacagagacactgggaccgaatctctgaattaactggaaccccatttgatgtggaatct gattctttttgtcttagaaatattatggaagcaccactacttaaaaataaggatgacatt gaggatatttgcatatctgccattaaggagaaggatattgaagctaagctgactcaggtg attgaaaactggaccaaccagaacttgagttttgcagcatttaagggaaagggagagctt cttctcaaaggaactgaatcaggagaaattatcaccttgatggaggatagtttaatggtc ttaggttccttactgagcaacagatacaatgctccatttaaaaaaactattcagaattgg gtgtataaattgtccacttcctcagatataattgaagagtggctagtagtccagaacctt tgggtttatcttgaagctgtcttcgtaggtggagatattgccaaacagctacctcaggaa gcaaagcggtttcagaatattgacaagtcatggataaaaataatgcagcgagctcacgag aaccccaatgtgatcagttgctgtgttggagatgaaaccatggggcaacttttacctcat ttgcatgaacagttggaagtatgtcagaagtcactcacagggtatttggagaagaagcga ttactatttccaagattcttctttgtatctgatccagttctcctggaaattcttggacaa gccagtgattcccacaccatacagccacatctccctgcagtgtctgacaacataaacgag gtgacatttcatgcaaaagactacgatcgtatcctggccgtcatatcaagagaaggagaa aaaattattttggatagtcctgttatggccaaaggtcctgtagagatttggctcatggat ttgttaaaaacgcagatgtcgtccctacataatataattagatctgcattctaccaaatc agcgattcaggatttcaactcttacctttcctcaatcacttcccagcacaggtgggactt ctgggaattcagatgttgtggacacacgattcagaagaggctttaaataatgcaaaagat gacaggaaaatcatgcatgtgaccaatcagaaatttttggatattctgaatactctaatt ggtcagacaacacatgatctaagcaagtttgacagagtgaagtttgaaactctgattacc atccatgtgcatcagagagatatttttgatgacttggtaaaaatgcacatcaaatcagtt actgactttgaatggctaaaacagagtagattttattttaaggaagatttggatcaaact gtggtgtccattacagatgtggattttatttaccagaatgaatttctgggatgcactgat cgtcttgtcatcactccattaacagacagatgctatatcaccttagcacaggctttggga atgaacatgggaggcgctccggcaggacctgcgggcactggcaaaacagaaactacgaaa gatatgggaagatgtttggggaaatacgtggtcgtatttaactgctcagatcaaatggat ttccgagggctaggacggatttttaaaggtcttgcacaatctggttcttggggctgtttt gatgagtttaacagaattgaattgcctgtgttatcagtggcagcccagcagatttatatt gttttgacagcaagaaaagagagaaaaaaacagttcattttttctgatggtgattgtgtt gatttgaatccagaatttggcatcttcctaacaatgaaccctggatatgctgggcgccag gaactaccagaaaacttaaaaattcagtttagaactgttgctatgatggttcctgataga cagatcattatgcgagttaaacttgcaagctgtggttttcttgaaaatgttatattggcg caaaagttttatgttctttataaactctgtgaagagcaacttaccaaacaggtccattac gactttgggttgagaaatattctatctgtattgagaacacttggagctcaaaaaagagcc agaccagaagacagtgagctaagcactgtcatgagaggactgagagacatgaacctttcc aagctggttgacgaagatgaacccctgttcctcagcttaatcaatgacctgtttccagga ttacagctggacagtagtacccacgcggagctgcaggctgccgtagccaaccaggttcaa ctagaaggtttgattaaccacccaccctggaacctcaagcttgtgcagttgtacgagaca tctctggtccgtcacggtttgatgactctggggcccagcggttctgggaagacgactgtc ataacaatcctgatgaaggcattaactgagtgcgggaggcctcacagagagatgcggatg aatcccaaagcgattactgcgcctcagatgtttggcagactggacaccgctactaatgac tggacagatgggattttttctacgctgtggagaaaaacgttaaaagctaaaaaaggtgaa aacattttcctcattttagatggccccgtggatgccatttggatcgagaacttaaattct gtgttggacgacaataaaaccctcacgctggccaacggagaccgcatccccatggccccg agctgtaagcttctgttcgaggtgcacaacatcgagaacgcttctcccgccacggtctcc aggatgggtatggtgtacatcagcagctctgcgctcagctggagggcgatcctgcaggcg tggctgaagaggcgcaccgcacaggaggcgaccgtgttcctcactctgtatgataaaata tttgaagatacatatacgtatatgaaactaaacctcaatccaaaaatgcagctcctggag tgtaactatatcatgcagtctctcaatctactggaaggtttaattccctccaaagaagaa ggtggtgtttcatgtgttgaacatcttcacaaattatttgtgtttggcctaatgtggagt ttaggagcccttttggagctggaaagcagagaaaagcttgaggcctttttacgcaatcat gaaagcaagttagacttaccagaaatacctaaaggcacgagtcagaccatgtatgagttt tatgttactgattacggtgactgggagcactggaataagaaacttcagccatattattat ccaactgacagtattccagaatattcatccattttggttccaaatgttgacaatgttaga acaaattttttgatagacaccattgcaaaacaacagaaagccgttttgctcacaggagag cagggaactgcaaaaactgtaatggtgaaggcctatttgaaaaaatacgatcctgaagta cagttatccaaaagtctgaacttttcgtctgccacagaacccatgatgtttcagagaaca atggaaagctacgtggataagcgaatgggaagcacgtatgggccgccaggaggcagaaaa atgactgtatttattgatgatattaatatgcctgtgattaatgaatggggagatcagata actaatgagattgtgcgacaaatgatggaaatggaaggaatgtatagcttggataagcct ggagacttcactactattgttgatgtgcagatcatagcggcaatgatccaccctggaggc ggtcgaaatgatattccccaacgtttaaaaagacagtttactgtgtttaattgcacattg ccttcaaatgcttcaatagacaaaatttttggacttattggttgtgggtacttcgatcct tgcagaaagttcaaacttgaagtatgtgagatgattgcaaatttagtttcagcaggcaga gtgctgtggcagtggaccaaggtgaagatgctgccaactccttctaaatttcattacatt ttcaatcttcgagatctttccagaatttggcaaggaatgttaaccataaaagccgaggag tgtgattcgatatctgttctcctatcacttttcaaacacgagtgcaacagagtaattgca gacaggtttgtaactcccgaagatgagcagtggtttaatatccatcttgttcgagcagtt gaagaaaacattaacccagatgtgacgtcgtatattcttcctgagccatacttcgtagat tttctccaggagatgcctgagccagccggcgatgaaccggaagacactgtgttcgaagtg cccaaagtttatgagctggtcccatcctttgactttctgtctgaaaaactccagttctac cagagacagttcaatgaaatcattagaggaacatctcttgatctagtgttttttaaagat gcaatgactcatcttattaagatttcacgaataattcgaacatcatgtggaaatgcgttg ctggtaggtgtcggtggttcaggaaaacaaagtctttcgagattggcctcttttatagct ggatatcaaatattccagattacattaaccaggtcttataatgtgaataatctaatagag gacttaaaaggtctgtacaaagttgctggtgctgatggaaaaggtatcaccttcatcttt actgacaatgaaataaaagatgaggcatttctagaatatcttaacaacctgttatcttca ggggagatctcaaatctgtttgcacgagatgagatggatgaaatcacccaaggtctaata tcggtgatgaaaaaggagctgcctcgccaccctcctacctttgacaatctgtatgagtat tttatttcaagatcaaggaagaacctgcatgttgttctctgcttttctccagttggtgag aagttccgtgcccgttctttgaaatttcctggcttgatatcaggttgcaccatggactgg tttagtcgctggccaaaagaggctttgattgctgtggcctcctacttcctttcaggctat agtattgtctgctccagtgacaccaaaagacaggtcgtagaaacaatgggcctcttccat gacatggtttccgaaagctgtgaaaattatttccaacgataccgccgaagagcacatgtg actcccaagtcttatctttcgtttataaatggttataaaagcatttatactgaaaaggtg aaacatatcaatgaacaggccgaacgtatgaatattggtcttgataagcttatggaggcg agcgagtctgtggctaagctgtctcaggatctcacagtgaaggaaaaggagctggccgtg gcttcggtaaaagcagacgaagtactggcagaagtcacggtaagtgctcaggcttcagcc aaagtgaaaaacgaagtgcaggaggtgaaagacaaagcccaaaaaattgtggatgaaatc gacagtgagaaagtaaaagctgagaccaagctggaggcggccaaacccgcccttgaagaa gcagaggcagccctgaatactatcaaaccaaatgatatcgccacagtcaggaaacttgca aagcccccgcatcttattatgagaatcatggactgtgtcctgttactatttcaaaagaaa attgacccagtcactatggatccagaaaaaccttgctgcaagccttcctggggagagtca ttaaaattgatgagtgcaacagggttcctgtggagcctccagcagttccccaaggacact ataaatgaagagactgttgagttgctgcagccgtattttaacatggatgattattctttg gaaaatgccaaaaaagtctgtgggaatgtggctggtctgctgtcttggacccttgctatg gcaacattttatggtatcaatagagaagtgttgcctctgaaggctaacctggccaagcag gagggccgtctggcagttgctaatgctgagttggggaaggcacaggcgctgctcgatgag aaacaaggcgagctggataaagtacaagcaaaatttgacgcagccatgagtgagaaaatg gatttgctaaatgatgcggatatgtgccgaaaaaagatgcaggcagcttctaccctcatc gatgggctgagtggggaaaaggtccgatggactcagcaaagcaaagagttcaaagctcag attaatagacttgtaggggatattctgctgtgcaccggattcctttcctaccttggtcct ttcaatcagatatttaggaactatttgcttaaagatcagtgggagatagagctgagagct cggaagattcctttcacagaaaacctgaatcttatttcgatgttggtggatccgccaaca attggggagtggggactgcagggattaccaggagatgacctctcaattcagaatggcatc attgtgacgaaggccaccagatacccactcctcatagacccgcagactcaaggcaaaact tggattaaatcaaaggaaagagaaaatgatttgcaagtaacatctctgaaccataaatat ttccgcacacacttggaggacagcctctccttgggccgaccccttctcattgaggacatt cgtgaagagctggatccagccctggataatgtattagaaaaaaatttcattaaatcaggc accacattcaaggtgaaagtcggtgataaggaatgtgatatcatggatacatttaaactt tatattactacgaagctacccaaccctgcctttacccctgagatcaatgctaaaacatca gtcattgattttaccgtcaccatgaaaggacttgagaatcaattattaaggagagtgatt ttaactgagaaacaggaattagagtctgagagggttaaacttttggaggatgtgaccttc aacaagcagaagatgaaggaacttgaagacaaccttctctacaagttaagcgccacaaaa ggttccttggtagacgatgaatctctcatcggtgttctccgaatcaccaagcagacggca actgaagtaagtgaaaagctgcacgtggccgcagagacggaaatcaaaattaacacagcg caggaggagttccggccggcagccacccgcggaagtatcctctactttctcatcacggaa atgagcatggtcaacatcatgtaccagacctcgctggcccagttcttgaaattgtttgac cagtccatggccagatccgagaagtctccactacctcaaaagagaattacgaatattatt gagtacctgacatacgaagtttttatatactctgtcagaggcctgtacgaaaaccacaga ttcctcttcgtgctcctcctgaccttgaagatcgatcttcagagagggaccgtgaagccc agggagtttcaggctctcatcaaagggggagcagctctggatctgaaagcctgccctccc aagccgtttcgctggatcctggatatgacctggctgaatcttgtggagctgagtaaactt ccacagtttgcagaaattatgaaccagatatctcgtaatgagaaaggatggaaaagctgg tttgataaagatgctccggaggaagaaattatccctgatggatataatgattcgctggat acctgccgcaaacttttacttatcaggtcttggtgcccagaccgtactgtttttcaagca agaaagtatattgcagattctttggaggataagtacacagaaccagttatcttaaatctg gagaaaacttgggaagaaagtgatacacggacacctttgatatgtttcctgtccatggga tctgatcccacaattcaaattgatgcactggccaagaaactgaagctggaatgcagaact atctcaatgggacaaggacaagaggtacatgctcgaaagctgattcagatgtccatgcag cagggtggctgggtattactgcaaaattgtcaccttggcctagaatttatggaagaattg ctagagacattaactaccactgaagccaatgctgactctttccgagtgtggataactact gagccccacgatcgatttccaattacgttgcttcagacttctctcaaattcactaatgag ccaccgcaaggcgtacgcgccggtttgaaaagaacatttgccggaattaatcaagacctt ctggatatcagtaatttacccatgtggaagccaatgctttatactgtagcatttttacac tccactgtgcaggagagacgcaaatttggtcccttaggatggaatattccctatgaattc aattctgctgactttgcagccagtgtccagttcattcagaatcacctcgatgaatgcgat attaaaaaaggtgtatcatggagtacagttcggtacatgattggagaagttcaatatgga ggcagagtgacagatgactttgataaacgtctacttaattgctttgctagagtctggttc agtgagaagatgtttgaaccatcgttctgtttttatactggatataaaatccccttgtgc aaaaccctggatcagtattttgagtacatccagtcactgccatccctagataaccccgaa gtctttgggctgcaccctaatgctgatatcacgtatcagagtaatactgcttctgctgtt cttgaaacaattaccaacattcaacccaaagagagtggagggggtgtgggagagacccgg gaagccatcgtttatagattatctgaagatatgctgagcaaactgcctcctgattacatt cctcatgaggtgaaagctcgtttgataaagatgggacatcttaattcaatgaacatattt cttagacaagaaattgacagaatgcaaaaagtcatctcaatacttcgcagtagcctgagt gatctaaaattggccattgaaggaacaatcattatgagtgagaatttgagagatgccctg gacaacatgtatgatgctcgcatacctcagatctggaaaagagtgtcctgggattcatcc acactgggcttctggtttaccgaacttctggaaagaaatgctcagttttctacttggata tttgaagggaggcccaatgtattttggatgactggtttctttaatccccaaggcttcctc acagcaatgaggcaagaagtgactcgtgcccacaaaggctgggccctggactccgtgacc atccacaacgaagttctgcggcagaccaaggaggagatcgcatcgccccctgtggaaggt gtgtatatttatgggctgtatatggatggagcagcctgggacagacggaatgggaagctc acagaatccactcccaaggtgctcttcacgcagctgcctgtgctgcacatctttgccgtt aattccatcgcgcccaaggaccccaagctgtatgtgtgtcctatttacaagaaacccagg cgtactgacttgaccttcatcactgtggtgtatttgcgaacggttttgtccccagatcac tggatcttgagaggagtagctcttttgtgtgacatcaagtaa

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