KEGG   Ailuropoda melanoleuca (giant panda): 100465476
Entry
100465476         CDS       T01329                                 
Symbol
MAPK14
Name
(RefSeq) mitogen-activated protein kinase 14 isoform X3
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
aml  Ailuropoda melanoleuca (giant panda)
Pathway
aml01522  Endocrine resistance
aml04010  MAPK signaling pathway
aml04015  Rap1 signaling pathway
aml04068  FoxO signaling pathway
aml04071  Sphingolipid signaling pathway
aml04114  Oocyte meiosis
aml04148  Efferocytosis
aml04218  Cellular senescence
aml04261  Adrenergic signaling in cardiomyocytes
aml04370  VEGF signaling pathway
aml04380  Osteoclast differentiation
aml04517  IgSF CAM signaling
aml04519  Cadherin signaling
aml04550  Signaling pathways regulating pluripotency of stem cells
aml04611  Platelet activation
aml04613  Neutrophil extracellular trap formation
aml04620  Toll-like receptor signaling pathway
aml04621  NOD-like receptor signaling pathway
aml04622  RIG-I-like receptor signaling pathway
aml04625  C-type lectin receptor signaling pathway
aml04657  IL-17 signaling pathway
aml04658  Th1 and Th2 cell differentiation
aml04659  Th17 cell differentiation
aml04660  T cell receptor signaling pathway
aml04664  Fc epsilon RI signaling pathway
aml04668  TNF signaling pathway
aml04670  Leukocyte transendothelial migration
aml04714  Thermogenesis
aml04722  Neurotrophin signaling pathway
aml04723  Retrograde endocannabinoid signaling
aml04728  Dopaminergic synapse
aml04750  Inflammatory mediator regulation of TRP channels
aml04912  GnRH signaling pathway
aml04914  Progesterone-mediated oocyte maturation
aml04917  Prolactin signaling pathway
aml04926  Relaxin signaling pathway
aml04932  Non-alcoholic fatty liver disease
aml04933  AGE-RAGE signaling pathway in diabetic complications
aml04935  Growth hormone synthesis, secretion and action
aml04936  Alcoholic liver disease
aml05014  Amyotrophic lateral sclerosis
aml05020  Prion disease
aml05022  Pathways of neurodegeneration - multiple diseases
aml05132  Salmonella infection
aml05133  Pertussis
aml05135  Yersinia infection
aml05140  Leishmaniasis
aml05142  Chagas disease
aml05145  Toxoplasmosis
aml05152  Tuberculosis
aml05161  Hepatitis B
aml05163  Human cytomegalovirus infection
aml05167  Kaposi sarcoma-associated herpesvirus infection
aml05169  Epstein-Barr virus infection
aml05170  Human immunodeficiency virus 1 infection
aml05171  Coronavirus disease
aml05205  Proteoglycans in cancer
aml05208  Chemical carcinogenesis - reactive oxygen species
aml05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
aml05415  Diabetic cardiomyopathy
aml05417  Lipid and atherosclerosis
aml05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:aml00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100465476 (MAPK14)
   04015 Rap1 signaling pathway
    100465476 (MAPK14)
   04370 VEGF signaling pathway
    100465476 (MAPK14)
   04668 TNF signaling pathway
    100465476 (MAPK14)
   04068 FoxO signaling pathway
    100465476 (MAPK14)
   04071 Sphingolipid signaling pathway
    100465476 (MAPK14)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    100465476 (MAPK14)
   04519 Cadherin signaling
    100465476 (MAPK14)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    100465476 (MAPK14)
  09143 Cell growth and death
   04114 Oocyte meiosis
    100465476 (MAPK14)
   04218 Cellular senescence
    100465476 (MAPK14)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    100465476 (MAPK14)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    100465476 (MAPK14)
   04613 Neutrophil extracellular trap formation
    100465476 (MAPK14)
   04620 Toll-like receptor signaling pathway
    100465476 (MAPK14)
   04621 NOD-like receptor signaling pathway
    100465476 (MAPK14)
   04622 RIG-I-like receptor signaling pathway
    100465476 (MAPK14)
   04625 C-type lectin receptor signaling pathway
    100465476 (MAPK14)
   04660 T cell receptor signaling pathway
    100465476 (MAPK14)
   04658 Th1 and Th2 cell differentiation
    100465476 (MAPK14)
   04659 Th17 cell differentiation
    100465476 (MAPK14)
   04657 IL-17 signaling pathway
    100465476 (MAPK14)
   04664 Fc epsilon RI signaling pathway
    100465476 (MAPK14)
   04670 Leukocyte transendothelial migration
    100465476 (MAPK14)
  09152 Endocrine system
   04912 GnRH signaling pathway
    100465476 (MAPK14)
   04914 Progesterone-mediated oocyte maturation
    100465476 (MAPK14)
   04917 Prolactin signaling pathway
    100465476 (MAPK14)
   04926 Relaxin signaling pathway
    100465476 (MAPK14)
   04935 Growth hormone synthesis, secretion and action
    100465476 (MAPK14)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100465476 (MAPK14)
  09156 Nervous system
   04728 Dopaminergic synapse
    100465476 (MAPK14)
   04723 Retrograde endocannabinoid signaling
    100465476 (MAPK14)
   04722 Neurotrophin signaling pathway
    100465476 (MAPK14)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100465476 (MAPK14)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    100465476 (MAPK14)
  09159 Environmental adaptation
   04714 Thermogenesis
    100465476 (MAPK14)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    100465476 (MAPK14)
   05208 Chemical carcinogenesis - reactive oxygen species
    100465476 (MAPK14)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    100465476 (MAPK14)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    100465476 (MAPK14)
   05161 Hepatitis B
    100465476 (MAPK14)
   05171 Coronavirus disease
    100465476 (MAPK14)
   05163 Human cytomegalovirus infection
    100465476 (MAPK14)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100465476 (MAPK14)
   05169 Epstein-Barr virus infection
    100465476 (MAPK14)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    100465476 (MAPK14)
   05135 Yersinia infection
    100465476 (MAPK14)
   05133 Pertussis
    100465476 (MAPK14)
   05152 Tuberculosis
    100465476 (MAPK14)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    100465476 (MAPK14)
   05140 Leishmaniasis
    100465476 (MAPK14)
   05142 Chagas disease
    100465476 (MAPK14)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    100465476 (MAPK14)
   05020 Prion disease
    100465476 (MAPK14)
   05022 Pathways of neurodegeneration - multiple diseases
    100465476 (MAPK14)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100465476 (MAPK14)
   05418 Fluid shear stress and atherosclerosis
    100465476 (MAPK14)
   05415 Diabetic cardiomyopathy
    100465476 (MAPK14)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    100465476 (MAPK14)
   04932 Non-alcoholic fatty liver disease
    100465476 (MAPK14)
   04933 AGE-RAGE signaling pathway in diabetic complications
    100465476 (MAPK14)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    100465476 (MAPK14)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:aml01001]
    100465476 (MAPK14)
Enzymes [BR:aml01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     100465476 (MAPK14)
Protein kinases [BR:aml01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   100465476 (MAPK14)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Kdo APH NAD_binding_8
Other DBs
NCBI-GeneID: 100465476
NCBI-ProteinID: XP_002914341
Ensembl: ENSAMEG00000000425
UniProt: A0A7N5JK52
LinkDB
Position
5
AA seq 360 aa
MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQ
SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ
KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT
GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVG
TPGADLLKKISSESARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAA
QALAHAYFAQYHDPEDEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPPLDQEEMES
NT seq 1083 nt   +upstreamnt  +downstreamnt
atgtctcaggagaggcccacgttctaccggcaggagctgaacaagacaatctgggaggtg
cccgagcgttaccagaatctgtccccggtgggctccggtgcctatggctccgtgtgtgct
gcttttgacacaaaaactgggttacgtgtggcagtgaagaagctctccagaccatttcag
tccattattcatgccaaaaggacctacagagaactgcggttacttaaacatatgaaacat
gaaaatgtgattggtctgttggatgtttttacacctgcaaggtctctggaggaattcaac
gatgtgtatctggtgacccatctcatgggagcagatctgaacaacattgtgaaatgtcag
aagcttacagatgaccatgttcagttcctcatctaccagattctccgaggtctcaagtat
atacattcagctgacataattcacagggacctaaaacctagtaatctagctgtgaatgaa
gactgtgagctgaagatcttggattttggactggcccgacatacagatgatgaaatgaca
ggctatgtggccaccaggtggtacagggctcctgagatcatgctgaactggatgcattac
aaccagacagttgatatttggtcagtgggatgcataatggccgagctgttgactggaaga
acgttgtttcctggtacagaccatattgatcagttgaagctcattttaagactcgttgga
accccaggggctgatcttttgaagaaaatctcctcagagtctgcaagaaattacattcag
tctttgacccagatgccgaaaatgaactttgcaaatgtatttattggtgccaatcccttg
gctgtcgacttgctggagaagatgcttgtattggactcagacaagagaattacggcagcc
caagccctcgcacacgcctactttgctcagtaccacgaccctgaggatgaaccagtggct
gatccttacgatcagtcctttgaaagcagggacctccttatagatgaatggaaaagcctg
acctacgatgaagtcatcagctttgtgccaccaccccttgaccaagaagagatggaatcc
tga

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