KEGG   Ailuropoda melanoleuca (giant panda): 100465648
Entry
100465648         CDS       T01329                                 
Symbol
RAC1
Name
(RefSeq) ras-related C3 botulinum toxin substrate 1
  KO
K04392  Ras-related C3 botulinum toxin substrate 1
Organism
aml  Ailuropoda melanoleuca (giant panda)
Pathway
aml04010  MAPK signaling pathway
aml04014  Ras signaling pathway
aml04015  Rap1 signaling pathway
aml04024  cAMP signaling pathway
aml04062  Chemokine signaling pathway
aml04071  Sphingolipid signaling pathway
aml04145  Phagosome
aml04148  Efferocytosis
aml04151  PI3K-Akt signaling pathway
aml04310  Wnt signaling pathway
aml04360  Axon guidance
aml04370  VEGF signaling pathway
aml04380  Osteoclast differentiation
aml04510  Focal adhesion
aml04520  Adherens junction
aml04530  Tight junction
aml04613  Neutrophil extracellular trap formation
aml04620  Toll-like receptor signaling pathway
aml04650  Natural killer cell mediated cytotoxicity
aml04662  B cell receptor signaling pathway
aml04664  Fc epsilon RI signaling pathway
aml04666  Fc gamma R-mediated phagocytosis
aml04670  Leukocyte transendothelial migration
aml04722  Neurotrophin signaling pathway
aml04810  Regulation of actin cytoskeleton
aml04932  Non-alcoholic fatty liver disease
aml04933  AGE-RAGE signaling pathway in diabetic complications
aml04972  Pancreatic secretion
aml05014  Amyotrophic lateral sclerosis
aml05020  Prion disease
aml05022  Pathways of neurodegeneration - multiple diseases
aml05100  Bacterial invasion of epithelial cells
aml05132  Salmonella infection
aml05135  Yersinia infection
aml05163  Human cytomegalovirus infection
aml05167  Kaposi sarcoma-associated herpesvirus infection
aml05169  Epstein-Barr virus infection
aml05170  Human immunodeficiency virus 1 infection
aml05200  Pathways in cancer
aml05203  Viral carcinogenesis
aml05205  Proteoglycans in cancer
aml05208  Chemical carcinogenesis - reactive oxygen species
aml05210  Colorectal cancer
aml05211  Renal cell carcinoma
aml05212  Pancreatic cancer
aml05231  Choline metabolism in cancer
aml05415  Diabetic cardiomyopathy
aml05416  Viral myocarditis
aml05417  Lipid and atherosclerosis
aml05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:aml00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100465648 (RAC1)
   04014 Ras signaling pathway
    100465648 (RAC1)
   04015 Rap1 signaling pathway
    100465648 (RAC1)
   04310 Wnt signaling pathway
    100465648 (RAC1)
   04370 VEGF signaling pathway
    100465648 (RAC1)
   04071 Sphingolipid signaling pathway
    100465648 (RAC1)
   04024 cAMP signaling pathway
    100465648 (RAC1)
   04151 PI3K-Akt signaling pathway
    100465648 (RAC1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    100465648 (RAC1)
   04148 Efferocytosis
    100465648 (RAC1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100465648 (RAC1)
   04520 Adherens junction
    100465648 (RAC1)
   04530 Tight junction
    100465648 (RAC1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    100465648 (RAC1)
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    100465648 (RAC1)
   04620 Toll-like receptor signaling pathway
    100465648 (RAC1)
   04650 Natural killer cell mediated cytotoxicity
    100465648 (RAC1)
   04662 B cell receptor signaling pathway
    100465648 (RAC1)
   04664 Fc epsilon RI signaling pathway
    100465648 (RAC1)
   04666 Fc gamma R-mediated phagocytosis
    100465648 (RAC1)
   04670 Leukocyte transendothelial migration
    100465648 (RAC1)
   04062 Chemokine signaling pathway
    100465648 (RAC1)
  09154 Digestive system
   04972 Pancreatic secretion
    100465648 (RAC1)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    100465648 (RAC1)
  09158 Development and regeneration
   04360 Axon guidance
    100465648 (RAC1)
   04380 Osteoclast differentiation
    100465648 (RAC1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100465648 (RAC1)
   05205 Proteoglycans in cancer
    100465648 (RAC1)
   05208 Chemical carcinogenesis - reactive oxygen species
    100465648 (RAC1)
   05203 Viral carcinogenesis
    100465648 (RAC1)
   05231 Choline metabolism in cancer
    100465648 (RAC1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    100465648 (RAC1)
   05212 Pancreatic cancer
    100465648 (RAC1)
   05211 Renal cell carcinoma
    100465648 (RAC1)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    100465648 (RAC1)
   05163 Human cytomegalovirus infection
    100465648 (RAC1)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100465648 (RAC1)
   05169 Epstein-Barr virus infection
    100465648 (RAC1)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    100465648 (RAC1)
   05135 Yersinia infection
    100465648 (RAC1)
   05100 Bacterial invasion of epithelial cells
    100465648 (RAC1)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    100465648 (RAC1)
   05020 Prion disease
    100465648 (RAC1)
   05022 Pathways of neurodegeneration - multiple diseases
    100465648 (RAC1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100465648 (RAC1)
   05418 Fluid shear stress and atherosclerosis
    100465648 (RAC1)
   05415 Diabetic cardiomyopathy
    100465648 (RAC1)
   05416 Viral myocarditis
    100465648 (RAC1)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    100465648 (RAC1)
   04933 AGE-RAGE signaling pathway in diabetic complications
    100465648 (RAC1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:aml04131]
    100465648 (RAC1)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:aml04147]
    100465648 (RAC1)
   04031 GTP-binding proteins [BR:aml04031]
    100465648 (RAC1)
Membrane trafficking [BR:aml04131]
 Exocytosis
  Small GTPases and associated proteins
   Rho GTPases
    100465648 (RAC1)
 Endocytosis
  Lipid raft mediated endocytosis
   Arf6-dependent endocytosis
    100465648 (RAC1)
  Macropinocytosis
   Ras GTPases
    100465648 (RAC1)
 Others
  NADPH oxidases (Nox) and associated proteins
   Nox associated proteins
    100465648 (RAC1)
Exosome [BR:aml04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   100465648 (RAC1)
  Exosomal proteins of other body fluids (saliva and urine)
   100465648 (RAC1)
  Exosomal proteins of colorectal cancer cells
   100465648 (RAC1)
  Exosomal proteins of bladder cancer cells
   100465648 (RAC1)
GTP-binding proteins [BR:aml04031]
 Small (monomeric) G-proteins
  Rho Family
   Rac/Cdc42 [OT]
    100465648 (RAC1)
SSDB
Motif
Pfam: Ras Roc Arf GTP_EFTU CagD
Other DBs
NCBI-GeneID: 100465648
NCBI-ProteinID: XP_034525676
Ensembl: ENSAMEG00000006764
UniProt: A0A7N5KFI8
LinkDB
Position
10:complement(4346861..4370254)
AA seq 192 aa
MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAG
QEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLR
DDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPP
PVKKRKRKCLLL
NT seq 579 nt   +upstreamnt  +downstreamnt
atgcaggccatcaagtgtgtggtggtgggagacggagctgtaggtaaaacttgcctactg
atcagttatacaaccaatgcatttcctggagaatacatccccactgtctttgacaactac
tccgccaatgttatggtagatggaaaaccggtgaatctgggcttatgggatacagctgga
caagaagattatgaccgattacgtcccttatcctatccgcaaacagatgtattcttaatt
tgcttttctcttgtgagtcctgcatcatttgaaaatgttcgagcaaagtggtaccctgaa
gtgcgacaccactgtcccaacacccccatcatcttggtggggactaaacttgatctcagg
gatgacaaagacacgatcgagaagctgaaggaaaagaagctgactcccatcacctacccg
cagggtctggccatggctaaggagatcggtgcggtaaaatacctggagtgctcggcgctc
acgcagcgaggcctcaagacagtgtttgatgaagcgattcgagcggttctctgtccccct
cctgtcaagaagaggaagagaaaatgcctgctgttgtaa

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