Ailuropoda melanoleuca (giant panda): 100465690 Help Entry 100465690         CDS       T01329                                  Symbol TSC2 Name (RefSeq) tuberin isoform X1   KO K07207   tuberous sclerosis 2 Organism aml  Ailuropoda melanoleuca (giant panda) Pathway aml04072   Phospholipase D signaling pathway aml04115   p53 signaling pathway aml04140   Autophagy - animal aml04150   mTOR signaling pathway aml04151   PI3K-Akt signaling pathway aml04152   AMPK signaling pathway aml04211   Longevity regulating pathway aml04218   Cellular senescence aml04714   Thermogenesis aml04910   Insulin signaling pathway aml04919   Thyroid hormone signaling pathway aml05163   Human cytomegalovirus infection aml05165   Human papillomavirus infection aml05168   Herpes simplex virus 1 infection aml05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:aml00001]  09130 Environmental Information Processing   09132 Signal transduction    04072 Phospholipase D signaling pathway     100465690 (TSC2)    04151 PI3K-Akt signaling pathway     100465690 (TSC2)    04152 AMPK signaling pathway     100465690 (TSC2)    04150 mTOR signaling pathway     100465690 (TSC2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     100465690 (TSC2)   09143 Cell growth and death    04115 p53 signaling pathway     100465690 (TSC2)    04218 Cellular senescence     100465690 (TSC2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     100465690 (TSC2)    04919 Thyroid hormone signaling pathway     100465690 (TSC2)   09149 Aging    04211 Longevity regulating pathway     100465690 (TSC2)   09159 Environmental adaptation    04714 Thermogenesis     100465690 (TSC2)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     100465690 (TSC2)   09172 Infectious disease: viral    05168 Herpes simplex virus 1 infection     100465690 (TSC2)    05163 Human cytomegalovirus infection     100465690 (TSC2)    05165 Human papillomavirus infection     100465690 (TSC2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01009 Protein phosphatases and associated proteins [BR:aml01009]     100465690 (TSC2) Protein phosphatases and associated proteins [BR:aml01009]  Protein serine/threonine phosphatases   Phosphoprotein phosphatases (PPPs)    Protein phosphatase-1     PP1-interacting proteins (PIPs)      100465690 (TSC2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Tuberin DUF3384 Rap_GAP Cnd1 HEAT Motif Other DBs NCBI-GeneID:  100465690 NCBI-ProteinID:  XP_002926559 Ensembl:  ENSAMEG00000017702 LinkDB All DBs Position 10:complement(37082935..37115395) Genome browser AA seq 1813 aa AA seqDB search MAKPTSKDSGLKEKFRILLGLGTPRPNPRSAEGKQTEFIITADILRELSVECGINNRIRV IGQICEVAKTKKFEEHAVEALWKAVADLLQPERPPEARHAVLALLKAIVQGQGDRLGVLR ALFFKVIKDYPSNEDLHERLEVFKALTDNGRHITYLEEELAGFVLQWMDVGLSSEFLLVL VNLVKFNSCYLDEYIASMVHMICLLCVQTVSSVDIEVSLQVLDAVVCYNCLPAESLPLFI VTLCRTINVKELCEPCWKLMRNLLGTHLGHSAIYNMCRIMEDRAYREDAPLLRGAVFFVG MALWGAHRLYSLKNSPTSVLPSFYEAMTCPNEVVSYEIVLSVTRLIKKYRRELQAVTWDL LLNIMERLLQQLQSLDSPELRAIVHDLLTTVEELCDQNEFHGSQERYFELVERCADQRPE SSLLNLITYRAQSIHPAKDGWIHNLQLLMERFFRNESRSAVRIKVLDVLSFVLLINRQFY EEELISSVVISQLSHVPEDKDPQVRKLATQLLVDLAEGCHTHHFNSLLDIVEKVIARPLS PPPELEERDVAAYSASLEDVKTAVLGLLVILQTKLYALPASHAMRVYESLVSHIRLHYRH NYTLPIASSIRLQAFDFLLLLRADSLHRLGLPSKDGAVRFSPYCVCDAMEPERGPEKKAS GPLSPPTGPPGPVPAGPAVRLGSLPYSLLFRVLLQCLKQEADWKVLKLVLSKLPESLRYK VLVFTSPCSVDQLSSALCSMLSGPRTLERLRGTPEGFSRTDLHLAVVPVLTALISYHNYL DKTRQREMVYCLEQGLIYRCASQCVVALAVCSVEMPDIIIKALPVLVVKLTHISATASMA IPLLEFLSTLARLPHLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRC RLPFRKDFVPYITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPKSLRIARPPKQGLNNS PPVKEFKESSAAEAFRCRSVSVSEHAVRSRIQTSLTSASLGSADENSMAQADDNLKNLHL ELTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLVTVTTSVGTGTRSL LGLDSGELQGGPELSSDPGAHVRQTKEAPAKLESQAGQQVCRGARDRVRSMSGGHGLRVG ALDTPASHFPGGPTAPGAQTALASKSERAPAGTQFPAQEKTSLAAYVPLLTQGWAEILVR RPTGNTSWLMSLENPLSPFSSDINSMPLQELSNALMAAERFKERRDTALYKSLSVPASGS AKPPPPPRSNTVASFSSLCQSSCQAKLHRTISWADSAVVLEEGSPSESHLSAEPTELEDF EATLGTDRRGGRAETYSRSSSSSSQEEKYPAEELAAGGIPIERAVSSEGARPSVELSFQP SQPLSKSSSSPELQTLQDILGDPGDKTDVGRLSPEAKARSQSGILDGAGASWSAPGEESQ GRGPVQPEGPLPSSCPRSPSGLRPRGYTISDSAPSRRGKRVERDAFKSRAGASNTEKVPG INPSFVFLQLYHSPFFGDESNKPILLPNESFERSVQLLDQIPSYDTHKIAVLYVGEGQSD SELAILSNEHGSYRYTEFLTGLGKLIELKDCQPDKVYLGGLDVCGEDGQFTYCWHDDIMQ AVFHIATLMPTKDVDKHRCDKKRHLGNDFVSIVYNDSGEDFKLGTIRGQFNFVHVIISPL DYECNLVSLQCRKDMEGLVDTSVAKIVSDRNLPFVARQMALHANMASQVHHSRSNPTDIY PSKWIARLRHIKRLRHRIREEAHYPNPSLPLLQTHPPGHARGPAQAPAEPVPTYETGQRK RLISSVDDFTEFV NT seq 5442 nt NT seq  +upstreamnt  +downstreamnt atggccaagcctacaagcaaagattcaggcttgaaggagaagttcaggattctgttggga ctgggaaccccgaggccaaaccccaggtctgcagagggcaaacagacggagtttatcatc accgcggacattctgagagaactgagtgttgaatgtggtatcaacaatcgcatccgggtg atagggcagatctgcgaggttgcaaaaacgaagaagtttgaagagcatgctgtggaggcg ctgtggaaggccgtggcggacctgttgcagccggagcggcccccggaggcccggcacgcg gtgctggctctgctgaaggccatcgtgcaggggcagggggaccgcttgggcgttctcagg gccctcttctttaaggtcatcaaggattacccctctaatgaagaccttcacgagagactg gaagtgttcaaggctctcacggacaatgggagacacatcacctacttggaagaagaactg gctggctttgtcctgcagtggatggacgtcggcctgtcctcagaattcctcctggtgctt gtgaacttggtcaagttcaacagctgttacctggatgaatacattgcatcaatggtccac atgatctgcctgctgtgtgtccagaccgtgtcatccgtggacatagaggtctcgctgcag gtgctggacgccgtggtctgctataactgcttgccggctgagagcctccccctgttcatc gtcaccctctgccgtaccatcaacgtcaaggagctctgcgagccttgctggaagctgatg cgtaacctgctgggcacccacctgggccacagcgccatctacaacatgtgtcgtatcatg gaggacagagcctacagggaagacgccccgctgctgagaggggccgtgttcttcgtgggc atggctctctggggagcgcaccggctctattccctcaagaactctccgacgtctgtgctg ccctcgttttatgaggccatgacctgtccaaacgaggtggtgtcctacgaaatcgtgctc tccgtaaccagactcatcaagaagtaccggcgggagctccaggcggtgacgtgggacctc ctgctgaacatcatggagcgcctgcttcagcagctccagagcctggacagcccggagctc agagccatcgtccacgacctgctgaccacggtggaagagctatgtgatcagaatgaattc cacggctctcaggagagatactttgagctggttgagcgatgcgcagaccagaggcctgag tcctccctcctgaatttaataacctaccgggctcagtcaatccatccggcgaaggatggc tggattcacaacctgcagctgctgatggagagattcttcaggaatgaatctcgcagtgct gtgcgcatcaaggtgctggacgtcctgtccttcgtgcttctcatcaacagacagttctat gaggaggagctgatcagctcggtggtcatctcacagctctcccacgtcccagaggacaaa gacccccaagtccggaaactggccacccagttgctggtggacctggccgagggctgtcat acccaccacttcaacagcctgctggacattgtggaaaaggtgattgcccgccccctttct ccacccccggagctggaggagagagacgtggcggcgtactcggcctccctagaggatgtg aagactgctgtcttggggctcctcgtcatccttcagaccaagctgtacgccttgcctgcc agccacgcgatgcgtgtgtacgagtcgctggtcagccatatccggctccactacaggcac aactacaccctgcccatcgccagcagcatccggctacaggcctttgacttcctgctgctg ctgagggccgactcgctgcaccgcctcggcctgcccagcaaggacggggccgtgaggttc agcccctactgtgtctgcgacgccatggagccagagagaggcccggagaagaaggccagt ggccccctgtcgcctcccactgggccgcccggccctgtgcccgcgggccccgcggtgcgg cttggctctctgccctactccctgctcttccgcgtcctgctgcagtgcttgaagcaggag gccgactggaaggtgctgaagctcgtgctcagcaagctgcccgagtccctgcgctacaaa gtgctcgtcttcacgtccccctgcagcgtcgaccagctgtcgtccgccctctgctccatg ctttcaggtcccagaactctggagcggcttcgaggcaccccggaagggttctctagaact gacctgcatctggctgtggttcccgtgttgacagcgctaatctcttaccacaactatttg gacaagaccagacagcgggagatggtgtactgcctggagcagggcctgatctaccgctgc gccagccagtgcgtggtggcgctggccgtctgcagtgtcgagatgccggacatcatcatc aaggcgcttcccgtgctggtcgtgaagctcacgcacatctcggccacggccagcatggcc attccactcctcgaattcctgtcaactttggccaggctgccccacctctacaggaacttc gcagcggagcagtacgcgagcgtgttcgccatctccctgccttacaccaacccctccaag tttaatcagtacatcgtgtgtctggcacatcacgtcatagccatgtggttcattagatgc cgcctgcccttcaggaaggattttgttccttacatcactaagggcctgcgctccaacgtc ctcctatcctttgatgacaccccggagaaggacagcttcagagcacgaagcaccagtctc aacgagaggcccaagagtttgaggatagccagaccccccaaacaaggcttgaataactct ccacccgtgaaagaattcaaggagagctctgcagccgaggccttccggtgccgcagcgtc agtgtgtctgaacatgcggtccgcagcaggatccagacgtctctcacaagcgccagcttg gggtctgcagacgagaattcgatggcccaggctgatgacaacttgaaaaatctccacctg gagctcacggaaacgtgtctggacatgatggccagatacgtgttctccaacttcacagcg gtccccaagaggtctcctgtgggagagtttctcctggctggtggcaggaccaaaacctgg ctggttgggaacaagcttgtcaccgtgacaacgagcgtggggaccgggacccggtcgctg ctgggcttggactctggagagctgcagggtggcccagagttgagctctgaccctggcgcg cacgtgagacagaccaaggaggcgcctgccaagctggagtcccaggcggggcagcaggtg tgccgcggggcccgggaccgggtccgctccatgtctgggggccacggccttcgtgttggt gccctggacactccggcctcccacttcccaggtggccccactgccccgggcgcacagacg gccctagccagcaagtctgagagggcgccagctggcacccagttcccagcacaggagaag acgagcctggcggcctacgtccccctgctgacccagggctgggcggagatcctggtccgg aggcctacagggaacaccagctggctgatgagcctggagaacccgctcagccccttctcc tcggacatcaacagcatgcctctgcaggagctgtctaacgcgctcatggccgccgagcgc tttaaggagcgtcgtgacacagccctgtacaagtcgctgtcagtgcccgcgtctggctcg gccaagccccctccgccaccccgctctaacactgtggcctctttctcctccctgtgccag tccagctgccaggcaaagctgcacaggaccatttcctgggcagactcggcggtggtccta gaggagggaagtccgagtgagagtcatttgtctgcggagcccacggagttggaggacttt gaggcaacgctaggcacagacaggcgcggcggccgcgcagagacatacagcaggtcatct tcaagctccagccaagaggagaagtaccctgcggaggagctggctgccggagggatcccc atcgagcgggccgtctcttctgagggcgcccggccttctgtggagctctccttccagccc tcccagcccctcagcaagtccagctcctcgcctgagctgcagaccctgcaggacatactt ggggaccctggggacaaaacggatgttggccggctgagccctgaggccaaggcacggtca cagtctgggatcctggacggggcaggtgcctcctggtcagccccaggtgaagagagccag ggccggggccccgtgcagcccgagggtcccttgccttccagctgcccccgctcccccagt ggcctgcggcccagagggtacaccatctctgattcggccccgtcacgcagaggcaagagg gtagagagggatgccttcaagagcagagccggggcctccaatactgagaaggtgccaggc atcaatcccagctttgtgttcctgcagctataccattcacccttctttggtgatgagtcc aacaagcccatccttctacccaatgagtccttcgagcggtcagtgcagcttctcgaccag attccatcctacgacacacacaagattgccgtcctgtacgtgggagaaggccagagcgac agcgagctcgccatcctgtccaacgagcacggctcgtacaggtacacagagttcctgacc ggcctgggcaagctcatcgagctcaaggactgccagccggacaaggtgtacctgggtggc ctggatgtatgtggggaggacggccagttcacctactgctggcatgacgacatcatgcaa gccgtcttccacattgccaccctgatgcccaccaaggacgtggacaagcaccgctgtgac aagaagcgtcacttaggcaacgacttcgtgtccatcgtctacaacgactccggcgaggac ttcaagctgggcaccatcagaggccagttcaacttcgtccatgtgatcatcagccccctg gactacgagtgcaacctggtgtccctgcagtgcaggaaagacatggagggtctcgtggac accagtgtggccaagatcgtgtctgaccgcaacctgccttttgtggcccgtcagatggct ctgcacgccaacatggcctcccaggtgcatcatagccgctccaaccccaccgacatctac ccctccaagtggatcgccaggctccgccacatcaagcggctccgccaccggatccgtgag gaagcccactaccccaaccccagcctgcccctgctgcagacgcaccccccgggccacgcc agaggccctgctcaggcgccggcagagcccgtgcccacgtacgaaacgggccagcggaag cgcctcatctcctcggtggacgacttcacagagttcgtgtga

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