Ailuropoda melanoleuca (giant panda): 100468087 Help Entry 100468087         CDS       T01329                                  Symbol NOS1 Name (RefSeq) nitric oxide synthase, brain   KO K13240   nitric-oxide synthase, brain [EC:1.14.13.39] Organism aml  Ailuropoda melanoleuca (giant panda) Pathway aml00220   Arginine biosynthesis aml00330   Arginine and proline metabolism aml01100   Metabolic pathways aml04020   Calcium signaling pathway aml04081   Hormone signaling aml04145   Phagosome aml04371   Apelin signaling pathway aml04713   Circadian entrainment aml04730   Long-term depression aml04926   Relaxin signaling pathway aml04970   Salivary secretion aml05010   Alzheimer disease aml05014   Amyotrophic lateral sclerosis aml05022   Pathways of neurodegeneration - multiple diseases aml05410   Hypertrophic cardiomyopathy aml05412   Arrhythmogenic right ventricular cardiomyopathy aml05414   Dilated cardiomyopathy aml05416   Viral myocarditis Brite KEGG Orthology (KO) [BR:aml00001]  09100 Metabolism   09105 Amino acid metabolism    00220 Arginine biosynthesis     100468087 (NOS1)    00330 Arginine and proline metabolism     100468087 (NOS1)  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     100468087 (NOS1)    04020 Calcium signaling pathway     100468087 (NOS1)   09133 Signaling molecules and interaction    04081 Hormone signaling     100468087 (NOS1)  09140 Cellular Processes   09141 Transport and catabolism    04145 Phagosome     100468087 (NOS1)  09150 Organismal Systems   09152 Endocrine system    04926 Relaxin signaling pathway     100468087 (NOS1)   09154 Digestive system    04970 Salivary secretion     100468087 (NOS1)   09156 Nervous system    04730 Long-term depression     100468087 (NOS1)   09159 Environmental adaptation    04713 Circadian entrainment     100468087 (NOS1)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     100468087 (NOS1)    05014 Amyotrophic lateral sclerosis     100468087 (NOS1)    05022 Pathways of neurodegeneration - multiple diseases     100468087 (NOS1)   09166 Cardiovascular disease    05410 Hypertrophic cardiomyopathy     100468087 (NOS1)    05412 Arrhythmogenic right ventricular cardiomyopathy     100468087 (NOS1)    05414 Dilated cardiomyopathy     100468087 (NOS1)    05416 Viral myocarditis     100468087 (NOS1) Enzymes [BR:aml01000]  1. Oxidoreductases   1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen    1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor     1.14.13.39  nitric-oxide synthase (NADPH)      100468087 (NOS1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  NO_synthase FAD_binding_1 Flavodoxin_1 NAD_binding_1 PDZ PDZ_6 PDZ_2 Motif Other DBs NCBI-GeneID:  100468087 NCBI-ProteinID:  XP_034494538 Ensembl:  ENSAMEG00000012563 UniProt:  G1M205 LinkDB All DBs Position 12:complement(13196536..13368765) Genome browser AA seq 1467 aa AA seqDB search MENQVFSVQQIQPNVISVRLFKRRVGGLGFLVKERVSKPPVIISDLIRGGAAEQSGLIQA GDIILAVNGQPLVDLSYDSALEMLRGIASETHVVLILRGPEGFTTHLETTFTGDGTPKTI RVTRPLGPPTTAVDLSHQSSAGKEHTPPVDGAAGPGNGPQHTQDSGQEAGSLSNTNGLAP RHPGQDPTKKSAGVAPQDGQNSELLKEIEPVLSLLASGSKGINGAGPSKAETKDVEVQVD RGVDGKSHKPLPLGVENDRVFSDLWGKGHVPVVLNNPYSEKEQPPASGKQSPTKNGSPSK CPRFLKVKNWETDVVLTDTLHLKSTLETGCTEHICMGSIMLPSQQIRRPEDVRTKEQLFP LAKEFIDQYYSSIKRFGSKAHTERLEEVNKEIETTGTYQLKDTELIYGAKHAWRNASRCV GRIQWSKLQVFDARDCTTAHGMFNYICNHIKYATNKGNLRSAITIFPQRTDGKHDFRVWN SQLIRYAGYKQPDGSILGDPANVEFTEICVQQGWKPPRGRFDVLPLLLQANGNDPELFQI PPELVLEVPIRHPKFEWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGVR DYCDNSRYNILEEVAKKMNLDMRKTSSLWKDQALVEINIAVLYSFQTDKVTIVDHHSATE SFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPEPWNTHVW KGTNGTPTKRRAIGFKKLAEAVKFSAKLMGQAMAKRVKATILYATETGKSQAYAKTLCEI FKHAFDAKVMSMEEYDIVHLEHETLVLVVTSTFGNGDPPENGEKFGCALMEMRHPNSVHE ERKYPEPLRFFPRKGPPLPQGDPGVRGLAAARDNQQRSYKVRFNSVSSCSDSHKSSGDGP DLRDNFESAGPLANVRFSVFGLGSRAYPHFCAFGHAVDTLLEELGGERILKMREGDELCG QEEAFRTWAKKVFKAACDVFCVGDDVNIEKANNSLISNDRSWKRNKFRLTYMAEAPELTQ GLSTVHKKRVSAARLLSRQNLQSPKSSRSTIFVRLHTNGNQELQYQPGDHLGVFPGNRED LVNALIERLEDAPPVNQLVKVELLEERNTALGVISNWTDEHRLPPCTIFQAFKYYLDITT PPTPLQLQQFASLATSEKEKQRLLVLSRGLQEYEEWKWGKNPTIVEVLEEFPSIQMPSTL LLTQLSLLQPRYYSISSSPDMYPDEVHLTVAIVSYRTRDGEGPIHHGVCSSWLNRVQADE VVPCFVRGAPSFHLPRNPQVPCILVGPGTGIAPFRSFWQQRQFDIQHKGMSPCPMVLVFG CRQSKIDHIYREETLQAKNKGVFRELYTAYSREPDKPKKYVQDVLQEQLAEPVYRALKEQ GGHIYVCGDVTMAADVLKAIQRIMTQQGKLSAEDAGVFISRLRDDNRYHEDIFGVTLRTY EVTNRLRSESIAFIEESKKDTDEVFSS NT seq 4404 nt NT seq  +upstreamnt  +downstreamnt atggagaatcaggtgttcagtgttcagcagatccaacccaacgtcatttctgtccgcctc ttcaagcgcagggtggggggcctgggcttcctggtgaaagagcgggtgagcaagccgccc gtgatcatctctgacctgatccgagggggcgccgcggagcagagcggcctcatccaggcc ggcgacatcatcctcgctgtcaacggccagcccttggtggacctgagctatgacagtgcc ctggagatgctcaggggcatcgcctctgagacccacgtggtcctcattctgaggggccct gagggcttcaccactcacctggagaccaccttcaccggggacgggacccccaaaaccatc cgggtgacacggcccctgggtccccccaccacagctgtcgatctgtctcaccagtcatcg gccggcaaagagcacacaccgccagtggacggggccgcgggtcctggcaatgggccacag catacccaggacagtgggcaggaagctggctcactctcaaataccaacggcctggctccc agacaccctggccaggaccctaccaagaaaagtgccggggtggccccccaggacggccag aacagtgaactgctcaaggagatagagcctgtgctgagccttctcgccagtgggagcaaa gggatcaatggagcgggaccttccaaggcagagacaaaagatgtggaagtccaggtggac agaggtgtggatggcaagtcccacaaaccgctgcccttgggcgtggagaatgaccgagtc ttcagtgacctgtgggggaagggccatgtgcccgtcgtcctcaacaacccgtattcagag aaggagcagccccctgcctcgggaaaacagtctcccacaaagaatggcagcccctccaag tgcccccgctttcttaaggtcaagaactgggagaccgacgtggttctcaccgacaccctt caccttaagagcacactggaaacgggctgcaccgagcacatctgtatgggctccatcatg ctcccttctcagcaaatacgaaggcctgaagatgtccgcacaaaagaacagctcttccct cttgccaaagagttcattgatcagtactactcgtcaattaaaagatttggctccaaagcc cacacagagaggctggaagaggtgaacaaagagatcgagaccaccggcacctaccagctc aaagacacggagctcatctacggggcgaagcacgcctggcggaatgcctcccgctgcgtt ggcaggatccagtggtccaagctgcaggtgttcgatgcccgagactgcaccacggctcac gggatgttcaactacatctgtaaccacatcaagtacgccaccaacaaagggaacctcagg tctgccatcaccatatttccgcagaggactgacggcaagcacgatttccgagtctggaac tctcagctcatccgctacgccggctacaagcagcctgacggctccatcctaggggaccca gccaatgtggaattcacagagatctgcgtacagcagggctggaaacccccaaggggccgc ttcgatgtcctgccactcctgctccaggccaacggcaatgaccccgagctcttccagatt cctccagagctggtgttggaagtgcccatcagacaccccaagtttgagtggttcaaggat ctgggcctcaagtggtacggcctccccgctgtgtctaatatgctgctggagatcggcggc ctggagttcagcgcctgccccttcagtggctggtacatgggcacagagatcggcgttcgc gactactgtgacaactctcgatacaacatcctggaggaagtggccaagaagatgaacttg gatatgaggaagacatcctccctgtggaaggaccaggcgctggtggaaatcaacattgct gttctctacagcttccagactgacaaagtgaccatcgttgaccaccactctgccaccgag tccttcattaagcacatggagaatgaataccgctgccgggggggctgccccgctgactgg gtgtggatcgtgccccccatgtctggcagcatcaccccggtcttccaccaggagatgctc aactaccggctcaccccctccttcgaataccagcctgagccttggaacacccacgtgtgg aaaggtaccaatgggacccccacaaagcggcgagccatcggcttcaagaagctggcggaa gccgtcaagttctcggccaagctcatggggcaggcaatggccaagagggtcaaggcaacc atcctttatgccacagagacgggcaagtcgcaggcctatgctaaaaccttgtgcgagatc ttcaaacatgcctttgatgccaaggtgatgtccatggaagaatatgacattgtacacctg gaacatgaaactctggtcctggtggttaccagcacttttggcaatggagacccccctgag aatggggagaaattcggctgtgctttgatggaaatgagacaccccaactccgtgcatgag gaaaggaagtacccggaacccttgcgtttctttccccgtaaagggcctcccctcccccaa ggtgacccaggagttcgtggtctggctgcagcccgtgacaaccagcagaggagctacaag gtccgattcaatagcgtttcctcgtgttctgactcccataaatcgtcgggtgatgggcca gacctcagagacaactttgagagcgctggacccctggcaaatgtgaggttctctgtgttt ggccttggctcccgtgcttacccgcacttctgtgcctttggacatgctgtggacaccctc ctggaggagctgggaggagagaggatcctgaagatgagggaaggggatgagctctgtggg caggaagaggctttcaggacctgggccaagaaggtcttcaaggcagcctgtgatgtgttc tgtgtgggagatgacgtcaacatcgagaaggccaacaactccctcatcagcaatgaccgc agctggaagaggaacaaattccgcctcacctacatggccgaagctccagaacttacacaa ggtctgtccactgtccacaaaaagcgggtctcagctgctcgactcctcagccgtcagaac cttcagagccctaaatccagccgatcaaccatcttcgtgcgtctccacaccaacgggaat caggagctccagtaccagcctggggaccacctgggcgtcttcccaggcaaccgcgaggac ctcgtgaacgccctgatcgagcggctggaggacgcacccccggtcaaccagctggtgaag gtggagctgctggaggagcggaacacggctttgggagttatcagtaactggacagatgag caccgcctcccgccctgcaccatcttccaggccttcaagtattacctggacatcaccacg ccgccaacgccactgcagctgcagcagtttgcctccctggccaccagcgagaaagagaag cagcgtctgctggtcctcagcaggggtttgcaggagtacgaggaatggaaatggggcaag aaccccaccatcgtggaggtgctggaggagttcccgtccatccagatgccctccaccctg ctcctgacccagctgtccctgctgcagccccgctactattccatcagctcctccccagac atgtaccccgacgaggtgcacctcaccgtggccatcgtctcctaccgcacccgagatgga gaaggaccaattcaccacggcgtgtgctcctcctggctcaaccgggtacaggctgacgaa gtggtcccgtgttttgtgagaggagcacccagcttccacctgccccgaaacccccaagtg ccctgcatcctcgttggcccaggcactggcattgcccctttccgaagcttctggcagcag cggcaatttgatatccaacacaaagggatgagcccctgccccatggtcctggtgttcggg tgccggcaatccaagatagaccacatctacagggaggagacgctccaggccaagaacaag ggggtcttcagagaactgtacacggcctactcccgggagccagacaaaccaaagaagtac gtgcaggacgtcctgcaggagcagctggcagaaccggtgtaccgagccctgaaggagcaa gggggccacatctatgtctgcggggatgtcaccatggctgccgacgtcctcaaagccatc cagcgcatcatgacccagcaggggaaactctcagcggaggatgcaggcgtgttcatcagc aggctgagggatgacaaccggtaccacgaggatattttcggggtcaccctgcgaacgtat gaagtgaccaaccgccttagatctgaatccattgccttcattgaggagagcaaaaaagac actgacgaggttttcagctcctaa

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