Ailuropoda melanoleuca (giant panda): 100468422
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Entry
100468422 CDS
T01329
Symbol
TYK2
Name
(RefSeq) LOW QUALITY PROTEIN: non-receptor tyrosine-protein kinase TYK2
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
aml
Ailuropoda melanoleuca (giant panda)
Pathway
aml04217
Necroptosis
aml04380
Osteoclast differentiation
aml04620
Toll-like receptor signaling pathway
aml04621
NOD-like receptor signaling pathway
aml04630
JAK-STAT signaling pathway
aml04658
Th1 and Th2 cell differentiation
aml04659
Th17 cell differentiation
aml05145
Toxoplasmosis
aml05160
Hepatitis C
aml05161
Hepatitis B
aml05162
Measles
aml05164
Influenza A
aml05165
Human papillomavirus infection
aml05167
Kaposi sarcoma-associated herpesvirus infection
aml05168
Herpes simplex virus 1 infection
aml05169
Epstein-Barr virus infection
aml05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
aml00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
100468422 (TYK2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
100468422 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
100468422 (TYK2)
04621 NOD-like receptor signaling pathway
100468422 (TYK2)
04658 Th1 and Th2 cell differentiation
100468422 (TYK2)
04659 Th17 cell differentiation
100468422 (TYK2)
09158 Development and regeneration
04380 Osteoclast differentiation
100468422 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
100468422 (TYK2)
05160 Hepatitis C
100468422 (TYK2)
05171 Coronavirus disease - COVID-19
100468422 (TYK2)
05164 Influenza A
100468422 (TYK2)
05162 Measles
100468422 (TYK2)
05168 Herpes simplex virus 1 infection
100468422 (TYK2)
05167 Kaposi sarcoma-associated herpesvirus infection
100468422 (TYK2)
05169 Epstein-Barr virus infection
100468422 (TYK2)
05165 Human papillomavirus infection
100468422 (TYK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
100468422 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
aml01001
]
100468422 (TYK2)
Enzymes [BR:
aml01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
100468422 (TYK2)
Protein kinases [BR:
aml01001
]
Non-receptor tyrosine kinases
JAK family [OT]
100468422 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
SH2_1
FERM_F1
Kinase-like
Kdo
RA_2
FERM_C_FAK1
ABC1
Motif
Other DBs
NCBI-GeneID:
100468422
NCBI-ProteinID:
XP_011225952
Ensembl:
ENSAMEG00000011557
UniProt:
D2HGY7
LinkDB
All DBs
Position
4:complement(7460221..7478539)
Genome browser
AA seq
1182 aa
AA seq
DB search
MPLCHWGATTRDSRPDGDGAQPMATRGGLKVLLHWAGPGGGDPWVTFSEATLTAEEVCIH
IAQKVGITPSCLNLFALFDAQAQVWLPPNHVLEISRDMSLTLYFRMRFYFRNWHGTNPQE
PAVYRCGPPGAKSSSEQAEQGMQLLDPASFEYLFEQGKHEFVNDVASLWELSSEEEIHHF
KNESLGMAFLHLCHLALCHGVPLEKVAKKISFKDCIPRSFRQQIRRHNALTRLRLRNIFR
RFVRAFQPGHVSQQVIMVKYLATLEQLAPRFGTERVPVCRLQLPAQAGGEPYYIRDGGQA
PPEPGPDLAPGPPTHEVLVTGTGGIQWRPVQAEGPRGDGSSRNPHAGPTGKKTKAPEVVN
QPADRPREAPWAYFCDFRDITHVVLKERHVSIHCQDNKSLELTLPSRAAALSLVSLVDGY
FRLTADSSHYLCHEVAPPRLVMSIQEGIHGPLLEPFVLAKLRAEDGLYLVHWSASHLNRL
ILTVAQREQAPGTQHMHLRKFPIELQAGVFTLEGWDRSFPSVRELRAALQGCSLRAGDDC
FSLRRCCLPWPGEISNLIIMRGPRASTGPPNLSQLSFHRVCRDDITQLSHLGQGTRTNVY
EGILRVGGRSPEEGMADGEDPPTPSGDRGQELRVVLKVLDPSHHDIALAFYETASLMSQV
SHVHLAFVHGICVHGSENIMVTEYVEHGPLDVWLRREKGHTPVAWKVAVAQQLASALSYL
EDKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWIAPECLS
GGANSLTTAADKWGFGATLLEICFDGEAPLQGRGPSEKECFYQKQHRLPQPSCPELATLT
SQCLTYEPAQRPSFRTILRDLTQLQPQNLADVLAVNPDSPASDPTVFHKRYLKKIRDLGE
GHFGKVSLYCYDPTNDGTGEMVAVKALKADCSPQLRTGWRREIDILRTLYHKHIVKYKGC
CEDPGEKSVQLVMEYVPLGSLRDYLPRHSVGLAQLLLFAQQICEGMAYLHGQHYVHRDLA
ARNVLLDNDRLVKLGDFGLTKAVPEGHEYYRVREDGDSPVFWYAPECLKECKFYYASDVW
SFGVTLYELLTYCDSSQSPPSKFIELIGLTQGQMTVLRLTELLERGERLPRPERCPCEIY
LLMKNCWEAEASFRPTFQNLIPILKTAQEKYQGQAASVFNVC
NT seq
3549 nt
NT seq
+upstream
nt +downstream
nt
atgcctctgtgccattggggtgccaccaccagggacagcaggcctgatggcgatggagct
cagcccatggccaccaggggaggcctgaaggtccttctgcactgggctggccctggtggc
ggggacccctgggtcaccttcagcgaagccacactgaccgcagaggaggtctgcatccac
attgcacaaaaagttggtatcactccgtcctgcctcaatctctttgctctcttcgatgcc
caggctcaggtctggctgcccccaaaccatgtcttggagatctccagagacatgagcctg
acgttgtatttccgcatgaggttttatttccggaactggcacggcacaaaccctcaggaa
ccggctgtgtaccgctgtgggcccccaggggccaagtcttcctcagaacaggcagagcag
gggatgcaattgctggacccagcctcctttgagtacctctttgagcagggcaagcatgag
tttgtgaatgacgtggcatcactgtgggagctgtcgagtgaggaggagatccaccatttt
aagaacgagagtctgggcatggcctttctgcacctctgccacctggctctctgccatggc
gtccccctggagaaggtggccaagaagatcagcttcaaggactgcatcccgcgctccttc
cggcagcagatccggcggcacaacgcgctgacgcgtctacgcttgcggaacatcttccgc
aggttcgtgcgggccttccagccgggccacgtctcgcagcaggtcatcatggtcaagtac
ctggccacgctcgagcagctggcaccccgcttcggcacggagcgtgtgcccgtgtgccgc
ctgcagctaccggcccaggccggtggggagccctactacatccgggacggcgggcaggct
cccccagagcccgggccggacttggcccccggaccccccactcatgaggtgctggtgacg
ggcacgggtggcatccagtggcggccggtacaggcagagggtcccagaggcgatggcagc
agcaggaatccccatgctggcccaactgggaagaaaaccaaggccccagaggtggtcaac
cagccagcagacaggcctcgggaagcgccatgggcctacttctgcgacttccgggatatc
acgcacgtggtgctgaaagaacgccacgtcagcatccactgtcaggacaacaagagcctg
gagctgaccctgccttcccgggccgcagccctgtccttggtgtcgctggtggacggctat
ttccgcctgaccgccgactcgagccactacctgtgccacgaggtggctcctccgcggctg
gtgatgagcatccaggagggtatccacggacccctgctggagccgtttgtgctggccaag
ctgcgggcggaggatggtctctacctcgtgcactggagcgccagccacctcaaccgcctc
atcctcaccgtggcccagcgtgagcaggcaccgggcacacagcacatgcacctgcgtaaa
ttccccattgagctgcaggcgggggtcttcacgctggagggctgggaccggtcctttccc
agcgtgcgcgagctgcgagccgccctgcagggttgttccctgcgggctggcgatgactgt
ttctccctgcgccgctgctgcctaccgtggccgggagagatctccaacctcatcatcatg
cgggggcctcgggccagcacgggcccccccaacctcagccagctcagcttccaccgggtc
tgccgggatgacatcacccagctctcccacttgggccaaggcacaaggaccaatgtgtat
gagggcatcttacgagtggggggcagaagccccgaggagggcatggcagacggtgaggac
ccccccacgcccagtggggaccgtgggcaagagctccgagtggtactcaaggtgctggac
cccagtcaccatgacatcgccctggccttctacgagacagccagcctcatgagccaggtg
tcccacgtgcacctggccttcgtgcacggcatctgcgtgcacggctctgagaacatcatg
gtgacggagtacgtggagcacgggcccctggatgtgtggctgcggcgagagaagggccac
acgcctgtggcctggaaggtggcggtagcccagcagctggccagcgccctcagctacctg
gaagacaagaacctggttcatggtaatgtgtgtggccggaacattctgctggcacgactg
gggctggcggagggcaccagccccttcatcaagctgagtgaccccggtgtgggcctgggc
gccctttccagggaggagcgggtggagcggatcccctggatagcccccgagtgtctctct
ggtggagccaacagcctaaccaccgcagccgataaatggggctttggtgccacactcctg
gagatctgcttcgacggggaggcccctctgcagggccgtggcccctctgagaaagagtgt
ttctaccagaagcagcaccggcttcctcagccctcctgcccggagctggccacactcacc
agccagtgcctgacctatgaaccagctcagcggccctccttccgcaccatcctgcgtgac
ctcactcaactgcagccccagaatcttgctgacgtcttggctgtgaaccccgactcgcct
gcgtcggaccccaccgttttccacaagcgctatttgaaaaagatccgggatctgggcgag
ggtcatttcggcaaggtcagtctgtactgctacgaccccacgaacgacggcactggcgag
atggtggccgtgaaggccctcaaggcggactgcagcccccagctgcgcaccggctggagg
cgggagatcgacatcctgcgcacgctctaccacaagcacatcgtcaagtacaagggctgc
tgcgaggacccaggagagaagtcggtgcagctcgtcatggagtacgtgcccctgggaagc
ctgcgcgactacctgccgcggcacagcgttggactcgcgcagctgcttctcttcgctcag
cagatctgtgagggcatggcctaccttcacggacagcactacgtgcaccgagacctggct
gcccgcaacgtgctgctggacaacgacaggctggtcaaacttggggactttggcctgacc
aaggctgtgcctgagggccatgaatactaccgcgtgcgcgaggacggggacagccccgta
ttctggtatgccccagagtgcctgaaggagtgtaagttctactatgcgtccgacgtctgg
tccttcggggtcaccctgtacgagctgctgacctactgtgactccagccagagccccccc
tcgaaattcatcgagctcataggcctcacccaggggcagatgacggtgctgaggctcact
gagctgctggaacgaggggagaggctgccccggccagagagatgtccttgtgagatctat
ctcctcatgaagaactgctgggaggcagaggcttcattccgtcccaccttccagaacctc
atacccattctcaagaccgcccaggagaaataccaaggccaggccgcctcagtgttcaat
gtgtgctga
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integrated database retrieval system
