KEGG   Ailuropoda melanoleuca (giant panda): 100470076
Entry
100470076         CDS       T01329                                 
Symbol
MGST2
Name
(RefSeq) microsomal glutathione S-transferase 2 isoform X1
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
aml  Ailuropoda melanoleuca (giant panda)
Pathway
aml00480  Glutathione metabolism
aml00980  Metabolism of xenobiotics by cytochrome P450
aml00982  Drug metabolism - cytochrome P450
aml00983  Drug metabolism - other enzymes
aml01100  Metabolic pathways
aml01524  Platinum drug resistance
aml05200  Pathways in cancer
aml05204  Chemical carcinogenesis - DNA adducts
aml05207  Chemical carcinogenesis - receptor activation
aml05208  Chemical carcinogenesis - reactive oxygen species
aml05225  Hepatocellular carcinoma
aml05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:aml00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    100470076 (MGST2)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    100470076 (MGST2)
   00982 Drug metabolism - cytochrome P450
    100470076 (MGST2)
   00983 Drug metabolism - other enzymes
    100470076 (MGST2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100470076 (MGST2)
   05204 Chemical carcinogenesis - DNA adducts
    100470076 (MGST2)
   05207 Chemical carcinogenesis - receptor activation
    100470076 (MGST2)
   05208 Chemical carcinogenesis - reactive oxygen species
    100470076 (MGST2)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    100470076 (MGST2)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    100470076 (MGST2)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    100470076 (MGST2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:aml02000]
    100470076 (MGST2)
Enzymes [BR:aml01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     100470076 (MGST2)
Transporters [BR:aml02000]
 Other transporters
  Pores ion channels [TC:1]
   100470076 (MGST2)
SSDB
Motif
Pfam: MAPEG
Other DBs
NCBI-GeneID: 100470076
NCBI-ProteinID: XP_002916178
Ensembl: ENSAMEG00000010971
UniProt: G1LWS4
LinkDB
Position
5:complement(114464030..114485772)
AA seq 146 aa
MAGHSILLAAVSVLSACQQSYFALHVGKARLKYKVTPPAVSGSPEFERIFRAQQNCVEFY
PVFLITLWMAGWYFNQVFATCLGLLYIYARHQYFWGYSEAAKKRITGFRLSLGSLALLTV
LGALGIANSFLDEYLDLNVAKKLRPF
NT seq 441 nt   +upstreamnt  +downstreamnt
atggctgggcattcaatcttgctggctgctgtctcagtcctgtcggcgtgtcaacaaagt
tattttgctttgcatgtaggaaaagcaagattaaaatacaaagttacacccccggcagtc
tctgggtcaccagagtttgaaagaatatttcgtgcacaacaaaactgtgtggagttttac
cccgtatttctgattacattgtggatggctggatggtatttcaatcaagtttttgctacc
tgtctgggtctgctgtacatatatgcccgtcaccagtatttctggggatattcagaagca
gctaaaaaaaggatcaccggtttccggctgagtctggggagtctggccttgctgacagtc
ctaggcgccctgggaattgcaaacagcttcctggacgaatacctggacctcaatgtcgcc
aagaaactgagacccttctaa

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