Ailuropoda melanoleuca (giant panda): 100471659
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Entry
100471659 CDS
T01329
Symbol
ATIC
Name
(RefSeq) bifunctional purine biosynthesis protein PURH
KO
K00602
phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:
2.1.2.3
3.5.4.10
]
Organism
aml
Ailuropoda melanoleuca (giant panda)
Pathway
aml00230
Purine metabolism
aml00670
One carbon pool by folate
aml01100
Metabolic pathways
aml01523
Antifolate resistance
Module
aml_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
aml00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
100471659 (ATIC)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
100471659 (ATIC)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
100471659 (ATIC)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
aml04147
]
100471659 (ATIC)
Enzymes [BR:
aml01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase
100471659 (ATIC)
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.10 IMP cyclohydrolase
100471659 (ATIC)
Exosome [BR:
aml04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
100471659 (ATIC)
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SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
AICARFT_IMPCHas
MGS
Ribosomal_L12_N
Motif
Other DBs
NCBI-GeneID:
100471659
NCBI-ProteinID:
XP_034511020
Ensembl:
ENSAMEG00000003629
UniProt:
G1LAE5
LinkDB
All DBs
Position
2:177869039..177897641
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AA seq
592 aa
AA seq
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MAPSQLALFSVSDKTGLVEFARNLTAVGLDLIASGGTAKALRDAGLAVRDVSELTGFPEM
LGGRVKTLHPAVHAGILARNIPEDNADMARLDFSLIRVVVCNLYPFVKTVASPDVTVEQA
VEQIDIGGVTLLRAAAKNHARVTVVCEPEDYAAVSTEMKSSDSKDTSLETRRQLALKAFT
HTAQYDEAISDYFRRQYSKGISQMPLRYGMNPHQTPAQLYTLKPRLPITVLNGAPGFINL
CDALNAWQLVKELKEALGIPAAASFKHVSPAGAAVGIPLSEDEAKVCMVYDLYKTLTPIS
TAYARARGADRMSSFGDFVALSDVCDVPTAKIISREVSDGIVAPGYEDEALKILSKKKNG
SYCVLQMDQSYNPDENEVRTLFGLRLSQKRNNGVIDRSLFSNVVTKNKDLPESALRDLIV
ATIAVKYTQSNSVCYAKNGQVIGIGAGQQSRIHCTRLAGDKANYWWLRHHPQVLSMKFKT
GVKRAEISNAIDQYVTGTIGEDEDLIKWKALFEEVPELLTEAEKKEWVDKLSEVSVSSDA
FFPFRDNVDRAKRSGVAYIAAPSGSAADKVVIEACDELGIILAHTNLRLFHH
NT seq
1779 nt
NT seq
+upstream
nt +downstream
nt
atggcacccagccagctcgccttatttagtgtctctgacaaaacgggccttgtggaattt
gccagaaacctaactgctgttggtttggatctgatcgcctccggagggactgcaaaggct
ctcagggatgcggggctggcagtcagagatgtctctgagctgacggggtttcctgaaatg
ttaggggggcgtgtgaaaaccttgcatcctgcagtccatgctggaatcttggctcgtaat
atcccagaagataatgctgacatggccagacttgatttcagtcttataagagttgtcgtc
tgtaatctgtatccatttgtgaagacagtggcttctccagatgtaaccgttgaacaggct
gttgaacagattgatattggtggagtgaccctactgagagcagcagccaaaaaccatgct
cgagtgacagtagtatgtgaacccgaggactatgcagctgtgtccacagagatgaagagc
tccgacagcaaagacacctccttggagactagacgccagttagccttgaaggctttcact
catacggcacaatatgatgaagcaatttccgattacttcaggagacagtatagcaaagga
atatctcagatgcctttgaggtatggaatgaaccctcatcaaactcctgcccagttatac
acgctgaagcccaggcttcccatcacagttctaaatggagcccctggatttataaacttg
tgtgatgctttgaatgcctggcagctggtgaaggaactcaaagaagctttaggcattcca
gccgctgcctctttcaaacatgtcagcccagcaggtgctgctgttggaattccactcagt
gaagatgaggccaaagtctgcatggtctatgatctgtataaaacccttacacccatatca
actgcatatgcaagagcaagaggggctgataggatgtcttcatttggtgattttgttgca
ttatctgatgtttgtgatgtccctactgccaaaattatctccagagaggtatctgatggt
attgttgccccaggatacgaagatgaagctttgaaaatactttctaaaaagaaaaatggg
agctactgtgttcttcagatggatcagtcttacaatccagatgaaaacgaagtacgaact
ctctttggtcttcgtttaagtcagaagagaaataatggtgtcattgacaggtcattattt
agcaacgttgtgaccaagaataaagatttgccagagtctgcgctcagagacctcattgta
gccaccattgctgtgaagtacacacagtctaactccgtgtgctatgccaagaatggtcag
gttattggcattggagcaggacagcagtctcgaatacactgcacccgccttgcaggggat
aaggcaaactattggtggcttagacatcatccacaggttctttcaatgaagtttaaaact
ggagtgaagagagcagaaatctccaatgccattgatcagtatgttactggaaccattggc
gaggatgaagatttgataaagtggaaggctttgtttgaggaagtgcctgaattattaact
gaagcagagaagaaggaatgggttgacaaacttagtgaagtttctgtcagctctgatgcc
ttctttcctttcagggataatgtagacagagctaaaaggagtggtgtggcctacattgct
gctccttctggttctgctgccgacaaagttgtgattgaggcttgcgatgaactgggaata
atccttgctcatacgaatcttcggctctttcatcactga
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