Ailuropoda melanoleuca (giant panda): 100471829
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Entry
100471829 CDS
T01329
Symbol
PDHA1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
aml
Ailuropoda melanoleuca (giant panda)
Pathway
aml00010
Glycolysis / Gluconeogenesis
aml00020
Citrate cycle (TCA cycle)
aml00620
Pyruvate metabolism
aml00785
Lipoic acid metabolism
aml01100
Metabolic pathways
aml01200
Carbon metabolism
aml01210
2-Oxocarboxylic acid metabolism
aml04066
HIF-1 signaling pathway
aml04922
Glucagon signaling pathway
aml05230
Central carbon metabolism in cancer
aml05415
Diabetic cardiomyopathy
Module
aml_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
aml00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
100471829 (PDHA1)
00020 Citrate cycle (TCA cycle)
100471829 (PDHA1)
00620 Pyruvate metabolism
100471829 (PDHA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
100471829 (PDHA1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
100471829 (PDHA1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
100471829 (PDHA1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
100471829 (PDHA1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
100471829 (PDHA1)
Enzymes [BR:
aml01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
100471829 (PDHA1)
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
100471829
NCBI-ProteinID:
XP_034505873
Ensembl:
ENSAMEG00000016730
UniProt:
G1MEB0
LinkDB
All DBs
Position
X:15831141..15847189
Genome browser
AA seq
390 aa
AA seq
DB search
MRKMLAAVSRVLSGAAQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTRED
GLRYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRA
HGFTFTRGLSVREILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALA
CKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAAST
DYYKRGDFIPGLRVDGMDILCVREATRFAAAHCRSGKGPILMELQTYRYHGHSMSDPGVS
YRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPP
LEELGYHIYSSDPPFEVRGANQWIKFKSIS
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgaggaaaatgctcgccgctgtctctcgcgtgttgtcgggcgccgcccagaagccggca
agcagagttctcgtggcctcccgtaattttgcaaatgatgctacatttgaaattaagaaa
tgcgatcttcaccggctagaagagggcccccctgtcaccacagtgctcaccagggaggac
gggctcaggtactataggatgatgcagactgttcgccggatggagttaaaggcagatcag
ctgtataaacagaaaattattcgtggtttctgtcacttgtgtgatggtcaggaagcttgt
tgtgtgggcctggaggccggcataaatcccacagaccatcttatcacagcctatcgggct
catggctttacctttactcgtgggctttctgtccgagaaattctcgcagagcttacagga
agaagaggaggctgtgctaaagggaaaggtggatcgatgcatatgtatgccaagaacttc
tatgggggcaatggcatcgttggagctcaggtgcccctgggagcggggattgctctggcc
tgtaagtataatggaaaggatgaggtctgtttgactttatatggcgatggtgctgctaat
cagggtcagatatttgaagcttataacatggcagctttgtggaaattgccatgtattttc
atctgtgagaataaccgctatggaatgggaacgtccgttgagagagcagcggccagcact
gattactacaagagaggcgacttcattcctggactgagggtcgatggaatggatatcttg
tgtgtccgggaggcaacaaggtttgcagctgcccactgtagatctggaaaggggcccata
ctgatggagctacagacttaccgttaccatggacacagcatgagtgaccctggagtcagt
taccgtacacgagaagagattcaggaagtaagaagtaagagtgaccctattatgcttctc
aaggatagaatggtgaacagcaatctggccagtgttgaagaattaaaggaaattgacgtt
gaagtgaggaaagaaattgaggatgctgcccagtttgccactgctgatcctgaaccgcct
ttggaagaactaggctatcacatttacagcagcgacccgccttttgaagttcggggtgca
aatcagtggatcaagtttaagtccatcagttaa
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