Ailuropoda melanoleuca (giant panda): 100471874
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Entry
100471874 CDS
T01329
Symbol
SHMT1
Name
(RefSeq) serine hydroxymethyltransferase, cytosolic
KO
K00600
glycine hydroxymethyltransferase [EC:
2.1.2.1
]
Organism
aml
Ailuropoda melanoleuca (giant panda)
Pathway
aml00260
Glycine, serine and threonine metabolism
aml00630
Glyoxylate and dicarboxylate metabolism
aml00670
One carbon pool by folate
aml01100
Metabolic pathways
aml01200
Carbon metabolism
aml01230
Biosynthesis of amino acids
aml01240
Biosynthesis of cofactors
aml01523
Antifolate resistance
aml04981
Folate transport and metabolism
Module
aml_M00141
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:
aml00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
100471874 (SHMT1)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
100471874 (SHMT1)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
100471874 (SHMT1)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
100471874 (SHMT1)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
100471874 (SHMT1)
Enzymes [BR:
aml01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.1 glycine hydroxymethyltransferase
100471874 (SHMT1)
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GFIT
Motif
Pfam:
SHMT
DegT_DnrJ_EryC1
Motif
Other DBs
NCBI-GeneID:
100471874
NCBI-ProteinID:
XP_002923164
Ensembl:
ENSAMEG00000004675
UniProt:
G1LDK7
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All DBs
Position
17:11633433..11657942
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AA seq
484 aa
AA seq
DB search
MMTQVNRAPKDADLWSLHEKMLAQPLKDSDTEVYNIIKKESNRQRVGLELIASENFASRA
VLEALGSCLNNKYSEGYPGQRYYGGTEFIDELELLCQKRALQVYGLDPECWGVNVQPYSG
SPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGY
INYDQLEENARLFHPKLIIAGTSCYSRNLDYARLRKIADDNGAYLLADMAHISGLVAAGM
VPSPFEHCHVVSTTTHKTLRGCRAGMIFYRRGVRSVDPKTGKETLYNLESLINSAVFPGL
QGGPHNHAIAGVAVALKQAMTPEFRLYQRQVVANCRVLAETLMELGYKVVTGGSDNHLIL
VDLRSKGTDGGRAEKVLEACSIACNKNTCPGDKSALRPSGLRLGTPALTSRGLLEKEFQK
VAHFIHRGIELTLQIQNDVGAKATLKEFKEKLAGDEKHQRAVRALREEVESFASLFPLPG
LPDF
NT seq
1455 nt
NT seq
+upstream
nt +downstream
nt
atgatgactcaagtcaacagggctcccaaggatgctgacctgtggtccttgcatgaaaaa
atgctggcgcagcccctgaaagacagtgacaccgaggtttacaacatcatcaagaaggag
agtaaccgccagagggtcgggctggagctgatcgcctccgagaatttcgccagccgagca
gttttggaggccctaggctcttgcttaaataacaagtactccgaggggtacccaggccag
aggtactacggcgggaccgagttcatcgatgagctggagctcctgtgtcagaagcgagcg
ctgcaggtctacggtctggaccccgagtgctggggggtcaatgtccagccctactcaggc
tcccctgccaacttcgcagtctataccgccctggtggagccccacgggcgcatcatgggc
ctcgacctgcccgacggcggccacctgacccacggcttcatgacggacaagaagaaaatc
tctgccacgtccatcttttttgaatctatgccctataaggtaaacccagacactggctac
atcaactatgaccaactggaggaaaacgcccgtctcttccacccgaagctgattatcgca
ggaaccagctgctactcccgaaacctggactacgctcgcctgaggaagatcgcggacgac
aacggggcgtatctcctggccgacatggcgcacatcagcgggctggtggcggctggcatg
gtgccctccccctttgagcactgccacgtggtgtccaccactacccacaaaaccctgaga
ggctgccgggccggcatgatcttctaccggagaggagtgcgcagcgtggatcccaagacc
ggcaaagagactctctacaacctggagtcgcttatcaactcggccgtgttcccgggcctg
cagggcggtccccacaaccatgccattgctggggttgctgtggccctgaagcaagctatg
actccggaattccgactctaccaacgccaggtggtggccaactgccgggttctggctgag
accctgatggagctgggctacaaagtggtgacaggtggttctgacaaccatttgatcctt
gtggatctccgttccaaaggcacggatggtggaagggctgagaaggttctagaagcctgt
tctattgcctgtaataagaacacctgtccaggtgacaaaagcgcattgcggcccagcgga
ctgcgtctggggacaccagcactgacatcccgaggacttttggaaaaagagttccagaaa
gtagcccactttattcacagagggatagaactcactctgcagattcagaacgacgttggg
gccaaggccaccctgaaggagttcaaagagaaactggcaggggacgagaagcaccaaagg
gccgtcagggctctgagggaggaagtggagagcttcgcgtctctcttccctctgcctggc
ctgcctgacttctag
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