Ailuropoda melanoleuca (giant panda): 100472835
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Entry
100472835 CDS
T01329
Symbol
CACNA1S
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1S isoform X1
KO
K04857
voltage-dependent calcium channel L type alpha-1S
Organism
aml
Ailuropoda melanoleuca (giant panda)
Pathway
aml04010
MAPK signaling pathway
aml04020
Calcium signaling pathway
aml04022
cGMP-PKG signaling pathway
aml04024
cAMP signaling pathway
aml04260
Cardiac muscle contraction
aml04261
Adrenergic signaling in cardiomyocytes
aml04270
Vascular smooth muscle contraction
aml04723
Retrograde endocannabinoid signaling
aml04725
Cholinergic synapse
aml04726
Serotonergic synapse
aml04727
GABAergic synapse
aml04911
Insulin secretion
aml04912
GnRH signaling pathway
aml04921
Oxytocin signaling pathway
aml04924
Renin secretion
aml04925
Aldosterone synthesis and secretion
aml04927
Cortisol synthesis and secretion
aml04929
GnRH secretion
aml04934
Cushing syndrome
aml04935
Growth hormone synthesis, secretion and action
aml05010
Alzheimer disease
aml05020
Prion disease
aml05022
Pathways of neurodegeneration - multiple diseases
aml05207
Chemical carcinogenesis - receptor activation
aml05410
Hypertrophic cardiomyopathy
aml05412
Arrhythmogenic right ventricular cardiomyopathy
aml05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
aml00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100472835 (CACNA1S)
04020 Calcium signaling pathway
100472835 (CACNA1S)
04024 cAMP signaling pathway
100472835 (CACNA1S)
04022 cGMP-PKG signaling pathway
100472835 (CACNA1S)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
100472835 (CACNA1S)
04929 GnRH secretion
100472835 (CACNA1S)
04912 GnRH signaling pathway
100472835 (CACNA1S)
04921 Oxytocin signaling pathway
100472835 (CACNA1S)
04935 Growth hormone synthesis, secretion and action
100472835 (CACNA1S)
04924 Renin secretion
100472835 (CACNA1S)
04925 Aldosterone synthesis and secretion
100472835 (CACNA1S)
04927 Cortisol synthesis and secretion
100472835 (CACNA1S)
09153 Circulatory system
04260 Cardiac muscle contraction
100472835 (CACNA1S)
04261 Adrenergic signaling in cardiomyocytes
100472835 (CACNA1S)
04270 Vascular smooth muscle contraction
100472835 (CACNA1S)
09156 Nervous system
04727 GABAergic synapse
100472835 (CACNA1S)
04725 Cholinergic synapse
100472835 (CACNA1S)
04726 Serotonergic synapse
100472835 (CACNA1S)
04723 Retrograde endocannabinoid signaling
100472835 (CACNA1S)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
100472835 (CACNA1S)
09164 Neurodegenerative disease
05010 Alzheimer disease
100472835 (CACNA1S)
05020 Prion disease
100472835 (CACNA1S)
05022 Pathways of neurodegeneration - multiple diseases
100472835 (CACNA1S)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
100472835 (CACNA1S)
05412 Arrhythmogenic right ventricular cardiomyopathy
100472835 (CACNA1S)
05414 Dilated cardiomyopathy
100472835 (CACNA1S)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
100472835 (CACNA1S)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
aml04040
]
100472835 (CACNA1S)
Ion channels [BR:
aml04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
100472835 (CACNA1S)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Ion_trans
Ca_chan_IQ
GPHH
PKD_channel
CAC1F_C
Motif
Other DBs
NCBI-GeneID:
100472835
NCBI-ProteinID:
XP_019650078
Ensembl:
ENSAMEG00000012260
UniProt:
G1M175
LinkDB
All DBs
Position
8:complement(100844015..100911270)
Genome browser
AA seq
1869 aa
AA seq
DB search
MEPSSPHDEGLRKKQPKKPVPEILPRPPRALFCLTLQNPVRKACINIVEWKPFETIILLT
IFANCVALAVYLPMPEDDNNTLNLGLEKLEYFFLIVFSIEAAMKIIAYGFLFHQDAYLRS
GWNVLDFIIVFLGVFTVILEQVNVIQSNTAPMSSKGAGLDVKALRAFRVLRPLRLVSGVP
SLQVVLNSIFKAMLPLFHIALLVLFMVTIYAIIGLELFKGKMHKTCYFIGTDIVATVENE
KPSPCARTGSGRPCTINGSECRGGWPGPNHGITHFDNFGFSMLTVYQCITMEGWTDVLYW
VNDAIGNEWPWIYFVTLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKLREKQQLE
EDLRGYMSWITQGEVMDVEDLREGKLSLDEGGSDTESLYEIEGLNKIIQFVRHWRQWNRI
FRWKCHDVIKSKVFYWLVILVVALNTLSIASEHHNQPLWLTHLQDVANRVLLALFAVEML
MKMYGLGLRQYFMSVFNRFDCFVVCSGVLELVLVESGAMSPLGISVLRCIRLLRLFKITR
HWTSLSNLVASLLNSIRSIASLLLLLSLLLLISALLGMQLFGGRYDFEDTEVRRSNFDTF
PQALISVFQVLTGEDWNSMMYNGIMAYGGPSYPGVLVCVYFIILFVCGNYILLNVFLAIA
VDNLAEAESLTSAQKAKAEEKKRRKMSKGLPDKSEEEKSVIAKKLEQKPKGEGIPTTAKL
KIDEFESNVNEVKDPYPSADFPGDDEEDEPEIPVSPRPRPLAELQLKEKAVPIPEASSFF
IFSPTNKIRVLCHRIVNATWFTNFILLFILLSSAALAAEDPIRAESVRNQILGYFDIAFT
SVFTVEIVLKMTTYGAFLHKGSFCRNYFNILDLVVVAVSLISMGLESSAISVVKILRVLR
VLRPLRAINRAKGLKHVVQCVFVAVRTIGNIVLVTTLLQFMFACIGVQLFKGKFFSCNDL
SKMTEKECRGYYYVYKDGDPTQMELRPRQWIHSDFHFDNVLSAMMSLFTVSTFEGWPQLL
YQAIDSYKEDVGPVYNHRVEMAIFFITYIILIAFFMMNIFVGFVIVTFQEQGETEYKNCE
LNKNQRQCVQYALKARPLRCYIPKNPYQYQVWYVVTSSYFEYLMFALIMLNTVCLGMQHY
NQSEEMNHISDILNVAFTIIFTLEMVLKLMAFKARGYFGDPWNVFDFLIVIGSIIDVILS
EIDTFLASSGGLYCLGGGCGNVDPDESARISSAFFRLFRVMRLIKLLSRAEGVRTLLWTF
IKSFQALPYVALLIVMLFFIYAVIGMQMFGKIAMVDGTQINRNNNFQTFPQAVLLLFRCA
TGEAWQEILLACSYGKLCDRESDYAPGEEYTCGTDFAYYYFISFHMLCAFLIINLFVAVI
MDNFDYLTRDWSILGPHHLDEFKAIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKFCP
HRVACKRLVGMNMPLNSDGTVTFNATLFALVRTALKIKTEGNFEQANEELRAIIKKIWKR
TSMKLLDQVIPPIGDDEVTVGKFYATFLIQEHFRKFMKRQEEYYGYRPKKDTIQIQAGLR
TIEEEAAPEIRRTISGDLTAEEELERAMVEAAMEEGIFRRTGGLFGQVDNFLERTNSLPP
VMANQRPLQFAEIEMEELESPVFLEDLSQDPSTNPLARANTNNANTNANIAYDNSNHSNS
VHYEREFPGETETPAARGAFGQLRRVLGPHSKSCVEELKGQLTPKEMPSSQASPAPCQHA
RAEPPLPEARRSPTPGALPEEASHSSRAKESSSLCQTPATAQLIQEALVRGGLDTLATDA
NFVMVTGQALADACQMAPEEVEVAATELLKRQESPEGLASALGRWSIRSPLGSLDQHQGS
QETLILPRP
NT seq
5610 nt
NT seq
+upstream
nt +downstream
nt
atggagccgtcctcaccccacgatgagggcctgaggaagaaacagcccaagaagcccgtt
cctgagattctgccaaggcccccccgggccctgttctgcttgaccctccagaaccccgtg
aggaaggcctgcatcaacatcgtggaatggaaacccttcgagacaatcatcttgctcacc
atctttgccaactgtgtggccctggctgtgtacctgcccatgccagaagatgacaacaac
actctgaaccttggcctggagaaactggagtatttcttcctcattgttttctcgattgaa
gccgccatgaagatcattgcctacggcttcctattccaccaggatgcctatctgcgcagc
ggctggaatgtgctagacttcatcattgtcttcctgggggttttcaccgtgattctggaa
caggttaacgtcatccaaagcaacacagccccgatgagcagcaaaggggctggtctggat
gtcaaggccctgagagccttccgcgtgctcagacccctccggctggtgtcaggggtgccg
agcctgcaggtggtcctcaactccatcttcaaggccatgctgcccctgttccacatcgcc
ctgctcgtcctctttatggtcaccatctatgccatcatcgggctggagctcttcaagggc
aagatgcataagacctgctactttatcgggacggatatcgtggccaccgtggagaatgag
aagccctcaccctgtgccaggacgggctcggggcgcccatgcaccatcaatggcagcgag
tgtcggggcggctggccggggcccaaccatggcatcacccactttgacaacttcggcttc
tccatgctcaccgtgtatcagtgcatcaccatggaggggtggaccgatgtcctctactgg
gtcaatgatgccatcgggaacgagtggccctggatctattttgtcaccctcattctgctg
ggatccttcttcattctcaacctggtgctgggtgtcctgagtggcgaattcactaaggag
cgggagaaggccaagtccaggggaaccttccagaagctccgggagaagcagcagctggag
gaggacctccgaggctacatgagctggatcacgcagggcgaggtcatggacgttgaggac
ttgagagaagggaagctgtctttggatgaaggaggctccgacacagagagcctgtatgaa
atcgagggcctgaacaaaatcatccagttcgtccgccactggaggcagtggaaccgcatc
tttcgctggaagtgccatgatgtgatcaagtccaaagttttctattggctggtgatcctg
gtcgtggccctcaacaccctgtctatcgcctcagagcaccacaaccagcctctgtggctg
acccacttgcaagacgtggccaaccgggtgctgctggcgctcttcgccgtcgagatgctg
atgaagatgtacgggctggggctgcgccagtacttcatgtccgtcttcaaccgattcgac
tgcttcgtggtgtgcagcggcgtgctggagctcgtgctcgtggagtcaggcgccatgagc
ccgctgggcatctccgtgctgcgctgcatccgcctacttaggctcttcaagatcaccagg
cattggacgtctctgagcaacctggtggcgtccctgctcaactccatccgctctatcgcc
tccctgctgctgctgctctccctccttctcctcatctccgccctgctgggcatgcagctc
ttcgggggcaggtacgacttcgaggacacggaggtgcgacgcagcaacttcgacaccttc
ccgcaggccctcatcagcgtcttccaggtcctgacgggggaagactggaactccatgatg
tacaacgggatcatggcctacggtggaccgtcctaccccggggtgctcgtgtgtgtttat
ttcatcatccttttcgtctgtggcaactatatcctgctcaacgtcttcctggccatcgcc
gtggacaacctggccgaagcagagagcctgacctctgcccagaaggccaaggcggaggag
aagaagcgcaggaagatgtccaagggtctcccagacaagtcagaggaggagaagtcagtg
atagccaagaagctggaacagaaacccaagggtgagggcatccctaccaccgccaagctg
aaaatcgatgaatttgaatctaatgtcaatgaagtaaaggacccctacccctcggctgac
ttcccaggcgatgatgaagaagatgagcctgagatccccgtgagcccccggccacgcccc
ctggccgagctgcaactgaaagagaaggcagtacccattccagaagccagctccttcttc
atcttcagccccaccaacaagatccgtgtcctgtgtcatcgcattgtcaacgccacctgg
ttcaccaacttcatcctgctcttcattctgctcagcagcgccgcgctggctgctgaggac
cccatccgggccgagtctgtgaggaaccagatccttgggtattttgacatcgcgttcacc
tctgtcttcaccgtggagatcgtcctcaagatgacgacctacggcgccttcctgcacaag
ggctccttctgccgcaattacttcaatatcctggacctggtggtggtggccgtgtccctt
atctccatgggacttgagtccagcgccatctccgtggtgaaaatcctgagggtgctgagg
gtgctccgacccctccgggccatcaacagagccaaagggctgaagcacgtggtgcaatgc
gtgtttgtggccgtccgcacaatcgggaacatcgtcctggtcaccaccctcctgcagttc
atgttcgcctgcatcggcgtccagctcttcaaggggaaattcttcagctgcaatgactta
tccaagatgacagagaaggagtgcaggggctattactatgtgtacaaggatggggacccc
acgcagatggagctgcgtccgcgccagtggatacacagtgatttccactttgacaacgtg
ctctcggccatgatgtcactcttcacggtctccacctttgagggatggcctcagctactt
taccaggccatcgactcgtacaaggaggacgtgggccccgtctacaaccaccgcgtggag
atggccatcttcttcatcacctacatcatcctcatcgccttcttcatgatgaacatcttc
gtgggctttgtcatcgtcaccttccaggagcagggggagaccgagtacaagaactgcgag
ctgaacaagaaccagcgccagtgcgtgcagtatgccctgaaggcccgcccgctgaggtgc
tatatccccaaaaacccataccagtaccaggtgtggtatgtggtcacctcgtcctacttc
gagtacctgatgtttgccctcatcatgctcaacaccgtctgcctgggcatgcagcactac
aaccagtccgaggagatgaaccacatctcagacatcctcaatgtggccttcaccatcatc
ttcaccctggagatggtcctcaagctcatggcgttcaaggccaggggctatttcggagac
ccctggaacgtgtttgacttcttgattgtcattggcagtatcatcgacgtcatcctcagt
gaaatcgacacattcctggcctccagcggaggactgtattgcctgggtggaggctgcggg
aacgttgaccccgacgagagtgcccgcatctccagcgccttctttcgcctgttccgggtc
atgaggctgatcaagctgctgagccgggcggagggagtacgcacgctcctatggaccttc
atcaagtccttccaggccctgccgtacgtggctctgctcatcgtcatgctgttcttcatc
tacgccgtcatcggcatgcagatgttcggtaagatcgccatggtggacgggacccaaata
aaccgcaacaacaacttccagaccttcccacaggctgtgctgctgctcttcaggtgcgcg
acgggtgaggcatggcaggagatcctcctggcctgcagctacggcaagctgtgtgaccgc
gagtccgactacgccccgggggaggagtacacgtgcggcaccgacttcgcctactattac
ttcatcagcttccacatgctctgtgccttcctgatcattaacctttttgttgctgtcatc
atggacaactttgactacctcacgcgggactggtccatcctgggccctcatcatctggat
gagttcaaggccatttgggcagagtatgacccggaggctaagggcagaatcaaacacttg
gatgtggtaaccctgctgagacggatccagccccctctgggctttgggaagttctgcccc
caccgggtggcatgtaagcgcctggtgggcatgaacatgcccttgaacagtgatggcacg
gtcaccttcaacgccactctcttcgccctggtccgtacggcactcaagatcaagacagaa
ggtaactttgagcaggccaatgaggagctgagggccatcatcaagaagatctggaagaga
accagcatgaagctcctggaccaggtcattcctccaataggagatgatgaggtgactgta
gggaagttctacgccacgtttctcatccaggagcacttccggaagttcatgaagcgtcag
gaagagtattatgggtatcggcccaagaaggacaccatacagatccaggccggattgcgg
accattgaggaagaggcagccccagagatccgccgcaccatctcaggagacctgaccgct
gaagaggagctggagagagccatggtagaggctgcgatggaggaagggatattccggagg
accggaggcctctttggccaggtggacaacttcctggaaaggaccaactccctacccccc
gtcatggccaaccagagacccctccaatttgctgagatagagatggaagagctggaatca
cctgtcttcttggaggatctctctcaagatccaagcaccaaccctcttgctcgtgccaat
accaacaatgccaacaccaacgccaacattgcctatgacaacagcaaccatagcaacagc
gtccactatgaaagggagttccctggagagacagagacgcctgctgccagaggagccttt
ggccaactccgaagggtcctgggaccccacagcaaatcctgtgtggaagagctaaaagga
cagctgaccccaaaagaaatgcccagctcccaggcatctcctgccccctgccagcatgcc
agggccgagcctcccctgcctgaggcaaggaggagccccaccccgggtgctctgcctgag
gaagcatcccacagcagtagggccaaggagagtagttccctgtgccagactccggcaaca
gcacagctgattcaagaggctctggttcgaggaggcctggacaccttggcgactgacgct
aactttgtcatggtgaccggccaggccctggcagatgcctgccagatggcaccagaagaa
gtggaggtggcagccacagagctgctgaaaagacaagagtccccagagggcctggccagt
gccctgggacgctggagcatcaggtccccgctgggcagcctggaccagcatcagggctcc
caggagaccctgatcctgcccaggccgtga
DBGET
integrated database retrieval system
