Ailuropoda melanoleuca (giant panda): 100473460
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Entry
100473460 CDS
T01329
Symbol
JAK1
Name
(RefSeq) tyrosine-protein kinase JAK1 isoform X2
KO
K11217
Janus kinase 1 [EC:
2.7.10.2
]
Organism
aml
Ailuropoda melanoleuca (giant panda)
Pathway
aml01521
EGFR tyrosine kinase inhibitor resistance
aml04151
PI3K-Akt signaling pathway
aml04217
Necroptosis
aml04380
Osteoclast differentiation
aml04550
Signaling pathways regulating pluripotency of stem cells
aml04620
Toll-like receptor signaling pathway
aml04621
NOD-like receptor signaling pathway
aml04630
JAK-STAT signaling pathway
aml04658
Th1 and Th2 cell differentiation
aml04659
Th17 cell differentiation
aml05140
Leishmaniasis
aml05145
Toxoplasmosis
aml05152
Tuberculosis
aml05160
Hepatitis C
aml05161
Hepatitis B
aml05162
Measles
aml05163
Human cytomegalovirus infection
aml05164
Influenza A
aml05165
Human papillomavirus infection
aml05166
Human T-cell leukemia virus 1 infection
aml05167
Kaposi sarcoma-associated herpesvirus infection
aml05168
Herpes simplex virus 1 infection
aml05169
Epstein-Barr virus infection
aml05171
Coronavirus disease
aml05200
Pathways in cancer
aml05203
Viral carcinogenesis
aml05212
Pancreatic cancer
aml05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
aml00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
100473460 (JAK1)
04151 PI3K-Akt signaling pathway
100473460 (JAK1)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
100473460 (JAK1)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
100473460 (JAK1)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
100473460 (JAK1)
04621 NOD-like receptor signaling pathway
100473460 (JAK1)
04658 Th1 and Th2 cell differentiation
100473460 (JAK1)
04659 Th17 cell differentiation
100473460 (JAK1)
09158 Development and regeneration
04380 Osteoclast differentiation
100473460 (JAK1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100473460 (JAK1)
05203 Viral carcinogenesis
100473460 (JAK1)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
100473460 (JAK1)
09162 Cancer: specific types
05212 Pancreatic cancer
100473460 (JAK1)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
100473460 (JAK1)
05161 Hepatitis B
100473460 (JAK1)
05160 Hepatitis C
100473460 (JAK1)
05171 Coronavirus disease
100473460 (JAK1)
05164 Influenza A
100473460 (JAK1)
05162 Measles
100473460 (JAK1)
05168 Herpes simplex virus 1 infection
100473460 (JAK1)
05163 Human cytomegalovirus infection
100473460 (JAK1)
05167 Kaposi sarcoma-associated herpesvirus infection
100473460 (JAK1)
05169 Epstein-Barr virus infection
100473460 (JAK1)
05165 Human papillomavirus infection
100473460 (JAK1)
09171 Infectious disease: bacterial
05152 Tuberculosis
100473460 (JAK1)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
100473460 (JAK1)
05140 Leishmaniasis
100473460 (JAK1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100473460 (JAK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
aml01001
]
100473460 (JAK1)
Enzymes [BR:
aml01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
100473460 (JAK1)
Protein kinases [BR:
aml01001
]
Non-receptor tyrosine kinases
JAK family [OT]
100473460 (JAK1)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
SH2_1
FERM_F1
ABC1
SH2
RIO1
FERM_C_FAK1
Motif
Other DBs
NCBI-GeneID:
100473460
NCBI-ProteinID:
XP_002924720
Ensembl:
ENSAMEG00000014980
LinkDB
All DBs
Position
2:complement(38534961..38661668)
Genome browser
AA seq
1153 aa
AA seq
DB search
MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEAPEPGVEVLFYLSDREPLRLGSGEYTAEEL
CIRAAQECCISPLCHNLFALYDENTKLWYAPNRTITVDDKTSLRLHYRMRFYFTNWHGTN
DNEQSVWRHSPKKQKNGYEKKKVPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ
DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI
NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN
WFHPNDSGNLLYYEVMVTGNLGIQWRQKPNVVPVEKEKNKLKRKKLENKHKKDEEKNKIR
EEWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH
HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT
CFEKSEVLGGQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFVLK
RCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDIVQGEHLGRGTRTHIYSGT
LVDYKDDEGTAEEKRIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRDV
ENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNLL
LAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFGT
TLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRAI
MRDINKLEEQNPDIVSERKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNT
GEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLPS
GSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIGD
FGLTKAIETDKEYYTVKDDRDSPVFWYAPECLIQCKFYIASDVWSFGVTLHELLTYCDSD
YSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPLHCPDEVYQLMRKCWEFQPSNRTT
FQNLIEGFEALLK
NT seq
3462 nt
NT seq
+upstream
nt +downstream
nt
atgcagtatctaaatataaaagaggactgcaatgccatggctttctgtgctaaaatgagg
agctccaagaagaccgaggtgaatctggaggctcccgagccaggggtggaagtgctcttc
tatctttcggatagggagcccctccggctgggcagcggggagtacacggcggaggagctc
tgcatcagggccgcgcaggaatgttgtatctctcctctgtgtcacaacctctttgctctg
tatgatgagaacaccaagctctggtatgccccgaatcgcaccatcactgttgacgacaag
acatcgctccggctccactaccggatgagattctatttcaccaactggcatgggaccaat
gataatgagcagtctgtatggcgacattctccaaagaagcagaaaaatggctatgagaaa
aaaaaagtcccagatgcaacccctctcctcgacgccagctctctggagtatctgtttgct
cagggacaatatgatttggtcaaatgcctggctcccattcgagaccccaagaccgagcag
gatgggcatgatatcgagaatgagtgtctgggcatggcagtcctggccatctcccactac
gctatgatgaagaagatgcagttgccagaactgcccaaggacatcagctacaagcgatat
attccagaaacattgaataagtccatcagacagaggaaccttctcaccaggatgcggata
aataatgttttcaaggatttcttgaaggaatttaacaacaagactatttgtgacagcagc
gtatctactcatgacctgaaggtgaaatacctggccaccttggaaactttgacaaaacat
tatggcgctgaaatatttgagacttccatgttactgatttcatcagaaaatgagatgaat
tggtttcatccgaatgacagtggaaaccttctctactatgaagtgatggtaactggaaat
cttggaatccagtggagacagaaaccaaatgttgttcctgttgaaaaggaaaaaaacaaa
ctgaaacggaaaaagctggaaaataaacacaagaaggatgaggagaaaaacaaaatccgg
gaagagtggaacaatttttcttacttccctgaaatcactcacattgtaataaaggagtct
gtggtcagcatcaataagcaggacaacaaaaaaatggaactgaagctctcatcccatgaa
gaggccttgtcctttgtgtccctggtagacggctacttccggctcacagcagatgcccat
cattacctctgcaccgatgtggctcccccgttgatcgtccacaacatacagaatggttgt
cacggtccaatctgcacggaatatgccatcaataagttgcggcaagaaggaagcgaggag
gggatgtatgtgctgaggtggagctgtaccgactttgacaatatcctcatgactgtcacc
tgctttgaaaaatctgaggtgctgggtggccagaaacagttcaagaactttcagatcgag
gtgcagaagggccgctacagcctgcacggctcggaccgcagcttccccagcctgggggac
ctgatgagccacctcaagaagcagatcctgcgcacagacaacatcagtttcgtgctgaag
cgctgctgccagcccaagccccgagagatctccaatctgcttgtggctactaagaaagcc
caagagtggcagcctgtctaccccatgagccagctgagttttgaccggatcctcaagaaa
gatattgtgcaaggcgagcacctcgggagaggcacacggacacacatctactctggtacc
ctggtggattacaaggatgacgaaggaactgcggaagaaaagagaataaaagtgatcctc
aaagtcttagaccccagccacagggacatttctctggccttctttgaggcagccagcatg
atgaggcaggtctcgcacaaacacatcgtgtacctctatggcgtctgtgtccgagatgtg
gagaatatcatggtggaggagtttgtggagggggggcccctggatctcttcatgcaccgg
aaaagtgatgtcctcaccacaccatggaagttcaaagttgccaagcagctggccagtgcc
ctgagttacttggaggataaagacctggtccacggaaacgtgtgcacgaaaaatcttctc
ctggcccgcgagggcattgacagtgagtgcggcccgttcatcaagctcagtgaccctggc
atccccatcactgtgctgtccaggcaagagtgcatagaacgaatcccatggattgctcca
gagtgtgttgaagactccaagaacctgagtgtggctgctgacaaatggagctttggaacc
acactctgggaaatctgctacaatggcgagatccctctgaaagacaagaccctgattgag
aaagagagattctacgaaagccggtgccggccagtgacaccatcttgtaaggagctggct
gaccttatgacccgctgcatgaactatgaccccaaccagagacctttcttccgagccatc
atgagagacatcaataaactggaagagcagaatccagacattgtttctgaaagaaagccg
gcaaccgaagtggatcccacacattttgaaaagcggttcttgaagaggatccgtgacttg
ggagagggccacttcgggaaggtcgagctctgcaggtatgaccctgagggggacaatact
ggggagcaggtggcagtcaaatccctgaagcccgagagtggaggtaaccacatagctgat
ctgaagaaggaaattgaaatcctaaggaacctctatcacgagaacattgtgaagtacaaa
ggcatctgtaccgaagacggaggaaatggtattaagctcatcatggaatttctgccttca
ggaagccttaaggaatatcttccaaagaataagaacaaaattaacctcaaacagcagtta
aaatatgccgttcagatttgtaaggggatggactatttgggttctcgtcagtatgttcac
cgggacttggcagcaagaaacgtcctcgttgagagtgagcaccaagtgaaaattggagac
tttggtttgaccaaagccattgaaactgacaaggagtactacacagtcaaggatgatcgg
gacagccctgtgttttggtatgctcccgaatgtttaattcagtgtaaattttatatcgcc
tctgacgtctggtcatttggagtgactctgcacgagctgcttacttactgtgactccgat
tacagccccatggcgttgttcctgaaaatgataggcccaactcatggccagatgacagtc
acaagacttgtgaatacattaaaagaaggaaaacgtttgccttgtccacttcactgtcca
gatgaggtttatcagcttatgagaaaatgctgggaattccaaccatccaatcggacaact
tttcagaaccttattgaaggatttgaagcacttttaaaataa
DBGET
integrated database retrieval system
