Ailuropoda melanoleuca (giant panda): 100474396
Help
Entry
100474396 CDS
T01329
Symbol
SOS2
Name
(RefSeq) son of sevenless homolog 2 isoform X9
KO
K03099
son of sevenless
Organism
aml
Ailuropoda melanoleuca (giant panda)
Pathway
aml01521
EGFR tyrosine kinase inhibitor resistance
aml01522
Endocrine resistance
aml04010
MAPK signaling pathway
aml04012
ErbB signaling pathway
aml04014
Ras signaling pathway
aml04062
Chemokine signaling pathway
aml04068
FoxO signaling pathway
aml04072
Phospholipase D signaling pathway
aml04150
mTOR signaling pathway
aml04151
PI3K-Akt signaling pathway
aml04510
Focal adhesion
aml04540
Gap junction
aml04630
JAK-STAT signaling pathway
aml04650
Natural killer cell mediated cytotoxicity
aml04660
T cell receptor signaling pathway
aml04662
B cell receptor signaling pathway
aml04664
Fc epsilon RI signaling pathway
aml04714
Thermogenesis
aml04722
Neurotrophin signaling pathway
aml04810
Regulation of actin cytoskeleton
aml04910
Insulin signaling pathway
aml04912
GnRH signaling pathway
aml04915
Estrogen signaling pathway
aml04917
Prolactin signaling pathway
aml04926
Relaxin signaling pathway
aml04935
Growth hormone synthesis, secretion and action
aml05034
Alcoholism
aml05160
Hepatitis C
aml05161
Hepatitis B
aml05163
Human cytomegalovirus infection
aml05165
Human papillomavirus infection
aml05200
Pathways in cancer
aml05205
Proteoglycans in cancer
aml05206
MicroRNAs in cancer
aml05207
Chemical carcinogenesis - receptor activation
aml05208
Chemical carcinogenesis - reactive oxygen species
aml05210
Colorectal cancer
aml05211
Renal cell carcinoma
aml05213
Endometrial cancer
aml05214
Glioma
aml05215
Prostate cancer
aml05220
Chronic myeloid leukemia
aml05221
Acute myeloid leukemia
aml05223
Non-small cell lung cancer
aml05224
Breast cancer
aml05225
Hepatocellular carcinoma
aml05226
Gastric cancer
aml05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
aml00001
]
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
100474396 (SOS2)
04630 JAK-STAT signaling pathway
100474396 (SOS2)
04068 FoxO signaling pathway
100474396 (SOS2)
04072 Phospholipase D signaling pathway
100474396 (SOS2)
04151 PI3K-Akt signaling pathway
100474396 (SOS2)
04150 mTOR signaling pathway
100474396 (SOS2)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
100474396 (SOS2)
04660 T cell receptor signaling pathway
100474396 (SOS2)
04662 B cell receptor signaling pathway
100474396 (SOS2)
04664 Fc epsilon RI signaling pathway
100474396 (SOS2)
04062 Chemokine signaling pathway
100474396 (SOS2)
09152 Endocrine system
04915 Estrogen signaling pathway
100474396 (SOS2)
04917 Prolactin signaling pathway
100474396 (SOS2)
04926 Relaxin signaling pathway
100474396 (SOS2)
04935 Growth hormone synthesis, secretion and action
100474396 (SOS2)
09156 Nervous system
04722 Neurotrophin signaling pathway
100474396 (SOS2)
09159 Environmental adaptation
04714 Thermogenesis
100474396 (SOS2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100474396 (SOS2)
05206 MicroRNAs in cancer
100474396 (SOS2)
05205 Proteoglycans in cancer
100474396 (SOS2)
05207 Chemical carcinogenesis - receptor activation
100474396 (SOS2)
05208 Chemical carcinogenesis - reactive oxygen species
100474396 (SOS2)
05231 Choline metabolism in cancer
100474396 (SOS2)
09162 Cancer: specific types
05210 Colorectal cancer
100474396 (SOS2)
05225 Hepatocellular carcinoma
100474396 (SOS2)
05226 Gastric cancer
100474396 (SOS2)
05214 Glioma
100474396 (SOS2)
05221 Acute myeloid leukemia
100474396 (SOS2)
05220 Chronic myeloid leukemia
100474396 (SOS2)
05211 Renal cell carcinoma
100474396 (SOS2)
05215 Prostate cancer
100474396 (SOS2)
05213 Endometrial cancer
100474396 (SOS2)
05224 Breast cancer
100474396 (SOS2)
05223 Non-small cell lung cancer
100474396 (SOS2)
09172 Infectious disease: viral
05161 Hepatitis B
100474396 (SOS2)
05160 Hepatitis C
100474396 (SOS2)
05163 Human cytomegalovirus infection
100474396 (SOS2)
05165 Human papillomavirus infection
100474396 (SOS2)
09165 Substance dependence
05034 Alcoholism
100474396 (SOS2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100474396 (SOS2)
01522 Endocrine resistance
100474396 (SOS2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RasGEF
RasGEF_N
RhoGEF
SOS1_NGEF_PH
PH
RHG20_PH
PH_19
IQ_SEC7_PH
PH_10
PH_13
Motif
Other DBs
NCBI-GeneID:
100474396
NCBI-ProteinID:
XP_019658125
Ensembl:
ENSAMEG00000009734
LinkDB
All DBs
Position
20:complement(25428897..25556375)
Genome browser
AA seq
1308 aa
AA seq
DB search
MKVQEQVHPNLSANEESLYYIEELIFQLLNKLCMAQPRTVQDVEERVQKTFPHPIDKWAI
ADAQSAIEKRKRRNPLLLPVDKIHPSLKEVLGYKVDYHVSLYIVAVLEYISADILKLAGN
YVFNIRHYEISQQDIKVSMCADKVLMDMFDQDDIGLVSLCEDEPRSSGELNYYDLVRTEI
AEERQYLRELNMIIKVFREAFLSDRKLFKPSDIDRIFSNISDIHELTVKLLGLIEDTVEM
TDESSPHPLAGSCFEDLAEEQAFDPYETLSQDILSPKFNEHFSKLMARPAVALHFQSIAD
GFKEAVRYVLPRLMLVPVYHCWHYFELLKQLKACSEEQEDRECLNQAITALMNLQGSMDR
IYKQYSPRRRPGDPVCPFYNRQLRSKHLAIKKMNEIQKNIDGWEGKDIGQCCNEFIMEGP
LTRIGAKHERHIFLFDGLMISCKPNHSQSRLPGYSSAEYRLKEKFVMRKIQICDKEDTCE
CKHAFELVSKDENSIVFAAKSAEEKNNWMAALISLHYRSTLDRMLDSVLLKEENEQPLRL
PSPEVYRFVVKDSEENIVFEDNLQSRSGIPIIKGGTVVKLIERLTYHMYADPNFVRTFLT
TYRSFCKPQELLSLLIERFEIPEPEPTEADKLAVEKGEQPISADLKRFRKEYVQPVQLRI
LNVFRHWVEHHFYDFERDLELLERLESFISSVRGKAMKKWVESIAKIIKRKKQAQANGIS
HNITFESPPPPTEWHISRPGQFETFDLMTLHPIEIARQLTLLESDLYRKVQPSELVGSVW
TKEDKEINSPNLLKMIRHTTNLTLWFEKCIVEAENFEERVAILSRIIEILQVFQDLNNFN
GVLEIVSAVNSVSVYRLDHTFEALQERKRRILDEAVELSQDHFKKYLVKLKSINPPCVPF
FGIYLTNILKTEEGNNDFLKKKGKDLINFSKRRKVAEITGEIQQYQNQPYCLRIEPEMRR
FFENLNPMGSASEKEFTDYLFNKSLEIEPRNCKQPPRFPRKSTFSLKSPGIRPNTGRHGS
TSGTLRGHPTPLEREPCKMSFSRIAETDIESTVSAPTSPNTPSTPPVSASSDLSVFLDVD
LSSSCGSNSIFAPVLLPHSKSFFSSCGSLHKLSEEPLIPPPLPPRKKFEDDASNSKGNTK
SDDDPPAIPPRQPPPPKVKPRAPAPTGAFDGPLHSPPPPPPRDPLPDTPPPVPLRPPEHF
LNCPFNLQPPPLGHLHRDPDWFRDVSTCPNSPNTPPSTPSPRVPRRCYVLSSSHNHLAHP
QAPPVPPRQSSSPHLPNLPKLPPKTYKRELSHPPSFRLPVLENAETPQ
NT seq
3927 nt
NT seq
+upstream
nt +downstream
nt
atgaaagttcaggagcaagtacatcccaatctctcagctaatgaagagtctctctattat
attgaagagctgatttttcagctgcttaataaattatgcatggctcaaccaaggactgtt
caagatgtggaggaacgtgttcaaaagacctttcctcatccaattgataaatgggctatt
gctgatgcacaatctgccatagaaaaacgaaaacgaagaaatcctctcttacttcctgtg
gacaaaatccatccttcattgaaggaagttttagggtacaaagtggactatcatgtatcc
ctatatattgtggctgtgctagagtatatctcagctgatattttgaagttggctggtaat
tatgtttttaatatccgacattatgaaatatctcagcaggacattaaagtgtcaatgtgt
gcagataaggttttgatggacatgtttgatcaggatgacataggtttggtttctctctgt
gaagacgaacctcgttcttcaggcgaattaaactactatgaccttgtcagaaccgaaatt
gcggaagaaaggcagtatctacgggaactcaatatgatcattaaagtgtttcgagaagcc
tttctttctgacagaaagctgtttaaaccttctgatattgacaggattttcagtaacatt
tcagatatacatgaattaactgtgaaacttttaggtttgattgaagacacagttgaaatg
actgatgaaagcagtcctcatccgttagcgggcagctgttttgaagatttggcagaagag
caagcatttgatccttatgaaacattatcacaggacattctttctccaaaatttaatgaa
cattttagtaagttgatggccagacctgcggtggctctacactttcagtccattgctgat
ggttttaaagaggcagttcgttatgtccttccacgccttatgctggtgcctgtttatcat
tgttggcactattttgaattattaaagcaattgaaagcatgtagtgaagagcaggaagac
agagaatgtttgaaccaagctattaccgctcttatgaatctccaaggtagtatggaccgg
atttacaagcagtattcacctagacgccgacctggggatcctgtttgccctttttataat
cgtcagttaagaagcaagcatctggctattaaaaaaatgaatgaaattcagaaaaacata
gatggatgggaagggaaagatattggacagtgttgtaatgaattcattatggaaggccca
ttgacacgaattggtgctaaacatgaacgacatatttttctcttcgatggcttaatgatt
agctgtaaacccaatcatagtcagtcacgccttccaggttatagtagtgcagaatacaga
ttaaaagagaaatttgtcatgaggaaaatacaaatatgtgataaagaagatacttgtgag
tgcaaacatgcttttgagttggtatccaaagatgaaaacagcatagtatttgctgctaag
tctgccgaagagaaaaacaattggatggccgcacttatttctcttcactatcgtagtaca
ctagatcgaatgctagattcagtgttattgaaagaagaaaatgagcaaccattgagatta
ccaagtcctgaagtgtatcgttttgtggtaaaagactctgaggaaaacattgtttttgaa
gacaacctgcaaagtagaagtggaatccccattattaaaggaggaactgtagtgaaatta
attgaaaggttaacatatcatatgtatgcagatcccaattttgttcgtacttttcttact
acataccgttcattttgtaaaccacaggaattgctaagcttactgattgaacgatttgaa
attccagagccagaacctactgaagcagataaattggccgtagagaaaggcgaacagccg
atcagcgcagaccttaaaaggtttcgcaaggaatatgtgcaaccagtacagcttaggatc
ttaaatgtgtttcggcactgggttgaacaccatttttatgactttgaaagggatttggag
ttgcttgaaagactagaatccttcatttcaagtgtaagagggaaagctatgaagaagtgg
gtagagtcaattgctaagatcatcaagagaaagaaacaagctcaggcaaatggaataagc
cataatattacctttgaaagtccacctccaccaactgaatggcatatcagcagaccaggg
cagtttgaaacatttgacctcatgacccttcatccaatagaaattgcacgtcagctgaca
cttttggaatctgatctctacaggaaagtccaaccttctgaactagtagggagtgtatgg
acgaaagaagataaagaaataaattctccaaatttgttaaaaatgattcgccataccaca
aacctcaccttatggtttgaaaagtgtattgtggaagcagaaaattttgaggaacgggtg
gcaatactaagtagaattatagaaattctgcaagtttttcaagatttgaataacttcaat
ggtgtattggagatagtcagtgcagtaaattcagtgtcggtatacagactagaccatact
tttgaggcattgcaggaaagaaaaaggagaattttggatgaagctgtggaattaagtcaa
gatcactttaaaaaatacctggtaaaacttaagtcaatcaatccaccttgcgtgcctttt
tttggaatatatttaacaaatattctgaaaactgaagaagggaataatgattttttaaaa
aagaaagggaaagatttaatcaatttcagtaagaggaggaaagtagctgaaattactgga
gaaattcagcagtatcagaatcaaccttactgtttacggatagaaccagaaatgaggagg
ttctttgaaaaccttaaccccatgggaagtgcttctgaaaaggagtttacggattatttg
ttcaacaaatcactagaaattgaaccccgaaactgcaaacagccacctcgatttcctagg
aaatcaactttctctttaaaatctcctggaatacggcctaatacaggccgacatggctct
acctcaggcactttacgaggtcatccaacgccattagaaagagaaccatgtaaaatgagc
tttagtcggattgctgaaactgatattgaatcaacggtgtcagcaccgacctctccaaat
acaccatctactccaccagtatctgcttcttcagaccttagtgtgtttttggatgtggat
ctcagcagttcctgtggcagcaatagcatctttgctccagtcctcttgccacattcaaaa
tctttcttcagctcctgtggtagtttacataaactgagtgaagagccgctgatcccccct
ccgcttcctcctcgaaaaaagtttgaggacgatgcttcaaactccaagggaaatacgaaa
tctgatgatgacccccctgctattccaccaagacagcctcctcctccaaaggtaaaaccc
agagctcctgctcctactggtgcatttgacgggcctctgcacagtccacctccaccgcca
ccaagagaccctcttcctgatacccctccaccagttccccttcggcctccagagcacttt
ctaaactgcccgtttaatcttcagccacctccactaggacatctgcacagagacccagac
tggttcagagatgttagtacctgcccaaactcgccaaatactcctcctagcacaccctct
ccgagagtaccacgtcgatgctacgtgctcagttctagtcacaaccaccttgctcatcct
caagctccccctgttccaccgaggcagagttcaagccctcacctgccaaacctaccaaaa
ctgccaccaaagacttacaaacgggagctttcgcaccctccgtcattcagactgcctgtg
ctagaaaatgcggaaactcctcagtga
DBGET
integrated database retrieval system
