Ailuropoda melanoleuca (giant panda): 100474469
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Entry
100474469 CDS
T01329
Symbol
ROCK1
Name
(RefSeq) rho-associated protein kinase 1 isoform X1
KO
K04514
Rho-associated protein kinase 1 [EC:
2.7.11.39
]
Organism
aml
Ailuropoda melanoleuca (giant panda)
Pathway
aml04022
cGMP-PKG signaling pathway
aml04024
cAMP signaling pathway
aml04062
Chemokine signaling pathway
aml04071
Sphingolipid signaling pathway
aml04270
Vascular smooth muscle contraction
aml04350
TGF-beta signaling pathway
aml04360
Axon guidance
aml04510
Focal adhesion
aml04520
Adherens junction
aml04530
Tight junction
aml04611
Platelet activation
aml04670
Leukocyte transendothelial migration
aml04810
Regulation of actin cytoskeleton
aml04921
Oxytocin signaling pathway
aml05135
Yersinia infection
aml05163
Human cytomegalovirus infection
aml05200
Pathways in cancer
aml05205
Proteoglycans in cancer
aml05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
aml00001
]
09130 Environmental Information Processing
09132 Signal transduction
04350 TGF-beta signaling pathway
100474469 (ROCK1)
04071 Sphingolipid signaling pathway
100474469 (ROCK1)
04024 cAMP signaling pathway
100474469 (ROCK1)
04022 cGMP-PKG signaling pathway
100474469 (ROCK1)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
100474469 (ROCK1)
04520 Adherens junction
100474469 (ROCK1)
04530 Tight junction
100474469 (ROCK1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
100474469 (ROCK1)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
100474469 (ROCK1)
04670 Leukocyte transendothelial migration
100474469 (ROCK1)
04062 Chemokine signaling pathway
100474469 (ROCK1)
09152 Endocrine system
04921 Oxytocin signaling pathway
100474469 (ROCK1)
09153 Circulatory system
04270 Vascular smooth muscle contraction
100474469 (ROCK1)
09158 Development and regeneration
04360 Axon guidance
100474469 (ROCK1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100474469 (ROCK1)
05206 MicroRNAs in cancer
100474469 (ROCK1)
05205 Proteoglycans in cancer
100474469 (ROCK1)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
100474469 (ROCK1)
09171 Infectious disease: bacterial
05135 Yersinia infection
100474469 (ROCK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
aml01001
]
100474469 (ROCK1)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
aml03036
]
100474469 (ROCK1)
Enzymes [BR:
aml01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.39 ROCK-subfamily protein kinase
100474469 (ROCK1)
Protein kinases [BR:
aml01001
]
Serine/threonine kinases: AGC group
DMPK family [OT]
100474469 (ROCK1)
Chromosome and associated proteins [BR:
aml03036
]
Eukaryotic type
Centrosome formation proteins
Kinases and associated factors
100474469 (ROCK1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Rho_Binding
PH
C1_1
Pkinase_C
APH
Motif
Other DBs
NCBI-GeneID:
100474469
NCBI-ProteinID:
XP_011227456
Ensembl:
ENSAMEG00000006719
UniProt:
G1LJU8
LinkDB
All DBs
Position
14:complement(58072260..58220540)
Genome browser
AA seq
1355 aa
AA seq
DB search
MSTGDSFETRFEKIDNLLRDPKSEVNSDCLLDGLDALVYDLDFPALRKNKNIDNFLSRYK
DTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAF
FWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYTA
EVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDY
ISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFP
DDNDISKEAKNLICAFLTDREVRLGRNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLS
SDIDTSNFDDLEEDKGDEETFPIPKAFVGNQLPFVGFTYYSNRRYLSSANPNDNRSSPNV
DKSLQENLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDKIMKELDEEGNQRRNLEST
VSQIEKEKMLLQHRINEYQRKAEQENEKRRNVENEVSTLKDQLEDLKKVSQNSQLANEKL
AQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSISQLESLNRELQERNRILENSKTQTD
KDYYQLQAVLEAERRDRGHDSEMIGDLQARITSLQEEVKHLKHNLERVEGERKEAQDMLN
HSEKEKNNLEIDLNYKLKSLQQRLEQEVNEHKVTKARLTDKHQSIEEAKSVAMCEMEKKL
KEEREAREKAENRVVQIEKQCSMLDVDLKQSQQKLEHLTENKERMEDEVKNLSLQLEQES
NKRLLLQNELKTQAFEADNLKGLEKQMKQEINTLLEAKRLLEFELAQLTKQYRGNEGQMR
ELQDQLEAEQYFSTLYKTQVKELKEEIEEKNREYLKKIQELQSEKETLATQLDLAETKAE
SEQLARGLLEEQYFELSQESKKAASRNRQEITDKDHAVSRLEETNSMLTKDIELLRKENE
ELTDKMRRAEEEYKLKKEEEISNLKAAFEKNINTERTLKTQAVNKLAEIMNRKDFKIDRK
KANTQDLRKKEKENRKLQLELNQEREKFNQMVVKHQKELNDMQAQLVEECTHKNELQMQL
ASKESDIEQLRAKLLDLSDSTSVASFPSADETDGNLPESRIEGWLSIPNRGNIKRYGWKK
QYVVVSSKKILFYNDEQDKEQSNPSMVLDIDKLFHVRPVTQGDVYRAETEEIPKIFQILY
ANEGECRKDVEMEPVQQAEKTNFQNHKGHEFIPTLYHFPANCEACAKPLWHVFKPPPALE
CRRCHVKCHRDHLDKKEDLISPCKVSYDVTSARDMLLLACSQDEQKKWVTHLVKKIPKNP
PSGFVRASPRTLSTRSAANQSFRKVVKNTSGKTSS
NT seq
4068 nt
NT seq
+upstream
nt +downstream
nt
atgtcgactggggacagttttgagactcggtttgaaaaaatcgacaacctgctgcgggat
cccaaatcggaagtgaattcagattgtttgctggatggattggatgctttggtatatgat
ttggattttcctgccttaagaaaaaacaaaaatattgacaactttttaagcagatataaa
gacacaataaataaaattagagatttacgaatgaaagcagaagattatgaagtagtgaag
gtgattggtagaggtgcatttggagaagttcaattggtaaggcataaatccaccaggaag
gtatatgctatgaagcttctcagtaaatttgaaatgattaagagatccgattctgctttt
ttttgggaagaaagggacatcatggcttttgctaacagcccttgggtcgtccagcttttc
tatgcattccaagatgatcgttatctctacatggtgatggagtacatgcctggcggagat
cttgtaaacttaatgagcaactatgatgtgcctgaaaaatgggcacgattctatactgca
gaagtagttcttgcattggatgcaatccattccatgggtttcattcatagagatgtgaaa
cctgataacatgctgctggataaatctggacatttgaagttagcagattttggtacttgt
atgaagatgaataaggaaggtatggtacgatgtgatacagcagttggaacacctgattat
atttcccctgaagtattaaaatctcaaggtggtgatggctattatggacgagaatgtgac
tggtggtcagttggggtatttttatatgaaatgcttgtaggtgatacacctttttatgca
gattctctggttggaacttacagtaagattatgaaccataaaaattcacttactttccct
gatgataatgatatatcaaaagaagcaaaaaatcttatttgtgccttcctcactgacaga
gaggtgagattagggcgaaatggtgtagaagaaatcaaacgacatctcttcttcaaaaat
gatcagtgggcttgggaaacactcagagacactgtagcaccagttgtacctgatttaagt
agtgacattgatacaagtaattttgatgacttggaagaagataaaggagatgaagaaaca
ttccccatacctaaagcttttgttggcaatcaattaccttttgtaggatttacatattat
agcaatcgtagatacttatcttcagcaaatcctaatgataaccgaagtagccccaatgtg
gataaaagcttgcaggaaaatttgcaaaaaacaatttataagctggaagaacagctgcat
aatgaaatgcaattaaaagatgaaatggagcagaagtgcagaacttcaaacataaaacta
gacaagataatgaaagaattggatgaagaggggaatcaaagaagaaacctagaatctaca
gtgtctcagattgagaaggagaaaatgttgctgcagcatagaattaatgagtaccagaga
aaagcagaacaggaaaatgagaagaggaggaatgtagaaaatgaagtttctacattaaag
gatcagttggaagacttgaagaaagtaagtcaaaattcacagcttgctaatgagaagctg
gcacaattacaaaagcagctagaagaagccaatgacttacttaggacagaatcagacaca
gccgtaagattaaggaagagtcacacagagatgagtaagtcaattagtcagctagagtcc
ctaaacagagaattgcaggagagaaatagaattttagagaattccaagacacagacggac
aaggactattaccagctgcaagctgtattagaagctgaacgaagagacagaggtcatgat
tctgagatgattggagaccttcaagctcgaattacatctttacaagaggaggtgaagcat
ctcaaacataatcttgaaagagtggaaggagaaagaaaagaagctcaagacatgcttaat
cactcagaaaaggaaaaaaataatttagagatagatttgaactataagcttaaatcatta
caacaacgtttagaacaagaggtaaatgaacataaagtaaccaaagctcgtttaactgac
aaacatcaatctattgaagaggcaaagtctgttgcaatgtgtgaaatggaaaaaaagctg
aaggaagagagagaagctcgagagaaggctgaaaatagagttgttcagattgagaagcag
tgttcaatgctagatgttgatctgaaacagtctcagcagaagctcgagcatttgactgaa
aataaagaaaggatggaggatgaagttaagaatctatcccttcaactggagcaggaatca
aacaagcgactgttgttacagaatgaattgaagactcaggcatttgaagcagacaattta
aaaggtctagaaaagcagatgaaacaggaaataaatactttattggaagcaaagagatta
ttagaatttgaattagctcagcttacaaaacagtataggggaaatgaaggacagatgcgg
gagctacaagatcagcttgaagctgagcagtatttctcgacactttataaaacccaggta
aaggaacttaaggaagaaattgaagaaaaaaacagagaatatttaaagaaaatacaagag
ctacaaagtgaaaaagaaactcttgctactcagttggatctagcagaaacaaaagctgag
tctgagcaattggctcgagggcttcttgaagaacagtattttgaattaagccaagaaagc
aagaaagctgcttccagaaataggcaagagattacagataaagatcatgctgttagtcgg
cttgaagaaacaaacagcatgttaaccaaagatattgaattattaaggaaagaaaatgaa
gagctaactgataaaatgaggagggcagaggaagaatataaattgaagaaggaggaggag
attagtaatcttaaggctgcctttgaaaagaatatcaatacagaaagaacccttaaaaca
caggctgttaacaagttggcagaaataatgaatcggaaagattttaaaattgatagaaag
aaagctaatacacaggatttgagaaagaaagaaaaggaaaatcgaaagctgcaactggaa
ctcaaccaagaaagagagaaattcaaccagatggtagtgaaacatcagaaggaactgaat
gacatgcaagcgcaattggtagaagaatgtacacataagaatgagcttcagatgcaattg
gctagcaaagagagtgatattgagcaattgcgtgctaaacttttggacctttcggattct
acaagtgttgctagttttcctagtgctgatgaaactgatggaaaccttccagagtcaaga
attgaaggttggctttcaataccaaatagaggaaatatcaaacgatatggctggaagaaa
cagtatgttgtggtaagcagcaaaaaaattctgttctataatgatgaacaagataaggaa
caatccaatccatccatggtattggacatagataaattgtttcacgttcgaccagtaacc
caaggagatgtttacagagctgaaactgaagaaattcctaaaatattccagatactatat
gcaaatgaaggtgaatgtagaaaagatgtagagatggaaccagtacaacaagctgaaaag
actaattttcaaaaccacaaaggccatgagttcattcctacactctaccactttcctgcc
aactgtgaggcctgtgccaaacctctctggcatgtttttaagccacctcctgccctagaa
tgtcgaagatgccatgttaagtgccacagagatcacttagataagaaagaggacttaatt
tctccatgtaaagtaagttatgatgtaacatcagcaagagatatgctgctgttagcatgt
tctcaggatgaacaaaaaaaatgggtaacacatttggtaaagaagatccctaagaatcca
ccttctggttttgttcgtgcatcccctcgaacactttctacaagatctgctgcaaatcag
tctttccgaaaagtggtcaaaaatacatctggaaaaactagcagttaa
DBGET
integrated database retrieval system
