KEGG   Ailuropoda melanoleuca (giant panda): 100474970
Entry
100474970         CDS       T01329                                 
Symbol
PPP3CB
Name
(RefSeq) serine/threonine-protein phosphatase 2B catalytic subunit beta isoform isoform X5
  KO
K04348  serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
Organism
aml  Ailuropoda melanoleuca (giant panda)
Pathway
aml04010  MAPK signaling pathway
aml04020  Calcium signaling pathway
aml04022  cGMP-PKG signaling pathway
aml04114  Oocyte meiosis
aml04218  Cellular senescence
aml04310  Wnt signaling pathway
aml04360  Axon guidance
aml04370  VEGF signaling pathway
aml04380  Osteoclast differentiation
aml04625  C-type lectin receptor signaling pathway
aml04650  Natural killer cell mediated cytotoxicity
aml04658  Th1 and Th2 cell differentiation
aml04659  Th17 cell differentiation
aml04660  T cell receptor signaling pathway
aml04662  B cell receptor signaling pathway
aml04720  Long-term potentiation
aml04724  Glutamatergic synapse
aml04728  Dopaminergic synapse
aml04921  Oxytocin signaling pathway
aml04922  Glucagon signaling pathway
aml04924  Renin secretion
aml05010  Alzheimer disease
aml05014  Amyotrophic lateral sclerosis
aml05020  Prion disease
aml05022  Pathways of neurodegeneration - multiple diseases
aml05031  Amphetamine addiction
aml05152  Tuberculosis
aml05163  Human cytomegalovirus infection
aml05166  Human T-cell leukemia virus 1 infection
aml05167  Kaposi sarcoma-associated herpesvirus infection
aml05170  Human immunodeficiency virus 1 infection
aml05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
aml05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:aml00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100474970 (PPP3CB)
   04310 Wnt signaling pathway
    100474970 (PPP3CB)
   04370 VEGF signaling pathway
    100474970 (PPP3CB)
   04020 Calcium signaling pathway
    100474970 (PPP3CB)
   04022 cGMP-PKG signaling pathway
    100474970 (PPP3CB)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    100474970 (PPP3CB)
   04218 Cellular senescence
    100474970 (PPP3CB)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    100474970 (PPP3CB)
   04650 Natural killer cell mediated cytotoxicity
    100474970 (PPP3CB)
   04660 T cell receptor signaling pathway
    100474970 (PPP3CB)
   04658 Th1 and Th2 cell differentiation
    100474970 (PPP3CB)
   04659 Th17 cell differentiation
    100474970 (PPP3CB)
   04662 B cell receptor signaling pathway
    100474970 (PPP3CB)
  09152 Endocrine system
   04922 Glucagon signaling pathway
    100474970 (PPP3CB)
   04921 Oxytocin signaling pathway
    100474970 (PPP3CB)
   04924 Renin secretion
    100474970 (PPP3CB)
  09156 Nervous system
   04724 Glutamatergic synapse
    100474970 (PPP3CB)
   04728 Dopaminergic synapse
    100474970 (PPP3CB)
   04720 Long-term potentiation
    100474970 (PPP3CB)
  09158 Development and regeneration
   04360 Axon guidance
    100474970 (PPP3CB)
   04380 Osteoclast differentiation
    100474970 (PPP3CB)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    100474970 (PPP3CB)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100474970 (PPP3CB)
   05170 Human immunodeficiency virus 1 infection
    100474970 (PPP3CB)
   05163 Human cytomegalovirus infection
    100474970 (PPP3CB)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100474970 (PPP3CB)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    100474970 (PPP3CB)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    100474970 (PPP3CB)
   05014 Amyotrophic lateral sclerosis
    100474970 (PPP3CB)
   05020 Prion disease
    100474970 (PPP3CB)
   05022 Pathways of neurodegeneration - multiple diseases
    100474970 (PPP3CB)
  09165 Substance dependence
   05031 Amphetamine addiction
    100474970 (PPP3CB)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100474970 (PPP3CB)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:aml01009]
    100474970 (PPP3CB)
Enzymes [BR:aml01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     100474970 (PPP3CB)
Protein phosphatases and associated proteins [BR:aml01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Calcineurin (PPP3/ PP2B)
    Catalytic subunits
     100474970 (PPP3CB)
SSDB
Motif
Pfam: Metallophos DUF5378
Other DBs
NCBI-GeneID: 100474970
NCBI-ProteinID: XP_011224729
Ensembl: ENSAMEG00000016865
LinkDB
Position
6:complement(76984637..77035086)
AA seq 480 aa
MDGIPRVDVLKNHLVKEGRVDEEIALRIINEGAAILRREKTMIEVEAPITVCGDIHGQFF
DLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWVLKILYPSTLFLLRGNHECRHL
TEYFTFKQECKIKYSERVYEACMEAFDSLPLAALLNQQFLCVHGGLSPEIHTLDDIRRLD
RFKEPPAFGPMCDLLWSDPSEDFGNEKSQEHFSHNTVRGCSYFYNYPAVCEFLQNNNLLS
IIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNC
SPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLSICSDDELMTEGEDQFDVGSAAARKEI
IRNKIRAIGKMARVFSVLREESESVLTLKGLTPTGMLPSGVLAGGRQTLQSATVEAIEAE
KAIRGFSPPHRICSFEEAKGLDRINERMPPRKDAVQQDGFNSLNTAHATENHGTGNHSAQ
NT seq 1443 nt   +upstreamnt  +downstreamnt
atggatgggatacccagggttgatgttctgaagaaccacttagtaaaagaaggtcgggta
gatgaagaaattgcacttagaattatcaatgagggtgctgccatccttcggagagagaaa
accatgatagaagtagaggctccaattacagtgtgtggtgacatccatggccaatttttt
gatctgatgaaactttttgaagtaggaggatcacctgctaatacacgatacctttttctt
ggtgattatgtggacagaggttattttagtatagagtgtgtcttatatttatgggtcctg
aagattctgtacccaagcacattatttcttctgagaggcaatcatgaatgcagacacctt
actgaatattttacctttaagcaggaatgtaaaattaaatactcagaaagagtctatgaa
gcttgtatggaagcttttgatagtctgcctcttgctgcacttttaaatcaacaatttctt
tgtgttcatggtggactttcaccagaaatacacacactggatgatattaggagattagat
agattcaaagagccacctgcatttggaccaatgtgtgacttgctatggtccgatccttct
gaagattttggaaatgaaaaatcacaggaacattttagtcacaatacagttcgaggatgt
tcttatttttataactatccagcagtgtgtgaatttttgcaaaacaataatttgttatcg
attattagagctcatgaagctcaagatgcaggctatagaatgtacagaaaaagtcaaact
acagggttcccttcattaataacaattttttcggcacctaattacttagatgtctacaat
aataaagctgctgtattaaagtatgaaaataatgtgatgaatattcgacagtttaactgt
tctccacatccttactggttgcccaattttatggatgtcttcacatggtctttaccattt
gttggagaaaaagtgacagaaatgttggtaaatgttctgagtatttgctctgatgatgaa
ctgatgactgaaggtgaagaccagtttgatgtaggttcagctgcagcccggaaagaaatc
ataagaaacaaaattcgagcaattggcaagatggcacgggtcttctctgttctcagggag
gagagtgaaagcgtgctgacactcaagggcctgactcccacagggatgttgcctagtgga
gtgttggctggaggacggcagaccctgcaaagtgccacagttgaggctattgaggctgaa
aaagcaatacgaggattctctccaccacatagaatctgcagttttgaagaggcaaagggt
ttggataggatcaatgagagaatgccaccccggaaagatgctgtacagcaagatggtttc
aattctctgaacaccgcacatgccactgagaaccacgggactggcaaccatagtgcccag
tga

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