KEGG   Ailuropoda melanoleuca (giant panda): 100475555
Entry
100475555         CDS       T01329                                 
Symbol
SOCS3
Name
(RefSeq) suppressor of cytokine signaling 3
  KO
K04696  suppressor of cytokine signaling 3
Organism
aml  Ailuropoda melanoleuca (giant panda)
Pathway
aml04120  Ubiquitin mediated proteolysis
aml04380  Osteoclast differentiation
aml04630  JAK-STAT signaling pathway
aml04668  TNF signaling pathway
aml04910  Insulin signaling pathway
aml04917  Prolactin signaling pathway
aml04920  Adipocytokine signaling pathway
aml04930  Type II diabetes mellitus
aml04931  Insulin resistance
aml04932  Non-alcoholic fatty liver disease
aml04935  Growth hormone synthesis, secretion and action
aml05160  Hepatitis C
aml05164  Influenza A
aml05168  Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:aml00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    100475555 (SOCS3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100475555 (SOCS3)
   04668 TNF signaling pathway
    100475555 (SOCS3)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    100475555 (SOCS3)
   04920 Adipocytokine signaling pathway
    100475555 (SOCS3)
   04917 Prolactin signaling pathway
    100475555 (SOCS3)
   04935 Growth hormone synthesis, secretion and action
    100475555 (SOCS3)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    100475555 (SOCS3)
 09160 Human Diseases
  09172 Infectious disease: viral
   05160 Hepatitis C
    100475555 (SOCS3)
   05164 Influenza A
    100475555 (SOCS3)
   05168 Herpes simplex virus 1 infection
    100475555 (SOCS3)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    100475555 (SOCS3)
   04932 Non-alcoholic fatty liver disease
    100475555 (SOCS3)
   04931 Insulin resistance
    100475555 (SOCS3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:aml04121]
    100475555 (SOCS3)
Ubiquitin system [BR:aml04121]
 Ubiquitin ligases (E3)
  Multi subunit type E3
   Cul5 complex
    Target recognizing subunit
     100475555 (SOCS3)
SSDB
Motif
Pfam: SH2 SOCS_box
Other DBs
NCBI-GeneID: 100475555
NCBI-ProteinID: XP_034496571
Ensembl: ENSAMEG00000019175
UniProt: D2H9A2
LinkDB
Position
13:complement(42098978..42101854)
AA seq 225 aa
MVTHSKIPAAGMSRSLDTSLRLKTFSSKSEYQLVVNAVRKLQESGFYWSAVTGGEANLLL
SAEPAGTFLIRDSSDQRHFFTLSVKTQSGTKNLRIQCEGGSFSLQSDPRSTQPVPRFDCV
LKLVHHYMPPPGTPSLPSPPTEPSSEVPEQPPSQPLPGNPPRRAYYIYSGGEKIPLVLSR
PLSSNVASLQHLCRKTVNGHLDSYEKVTQLPGPIREFLDQYDAPL
NT seq 678 nt   +upstreamnt  +downstreamnt
atggtcacccacagcaagattcccgccgccgggatgagccgctccctggacaccagcctg
cgcctcaagaccttcagctccaagagcgagtaccagctggtggtgaacgcagtgcgcaag
ctgcaggagagcggcttctactggagcgccgtgacgggcggcgaggcgaacctgctgctc
agcgccgagcccgccggcaccttcctcatccgcgacagctcggaccagcgccacttcttc
acgctcagcgtcaagacccagtcggggaccaagaatctgcgcatccagtgcgaggggggc
agcttctcgctgcagagcgacccccggagcacgcagccggtgccccgcttcgactgcgtg
ctcaagctggtgcatcactacatgccgccccccggcaccccttccttgccctctccaccg
accgaaccctcctccgaggtgccggagcagcctccctcccagccgctcccagggaatcct
cccaggagagcctattacatctactcggggggcgagaagatccctctggtgttgagccgg
cccctctcctccaacgtggcctctctccaacatctctgtcggaagaccgtcaatggccac
ctggactcctacgagaaagtcacccagctgcctgggcccattcgggaattcctggaccag
tacgatgcccctctttaa

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