KEGG   Ailuropoda melanoleuca (giant panda): 100476284
Entry
100476284         CDS       T01329                                 
Symbol
ATF4
Name
(RefSeq) cyclic AMP-dependent transcription factor ATF-4
  KO
K04374  cyclic AMP-dependent transcription factor ATF-4
Organism
aml  Ailuropoda melanoleuca (giant panda)
Pathway
aml04010  MAPK signaling pathway
aml04022  cGMP-PKG signaling pathway
aml04137  Mitophagy - animal
aml04141  Protein processing in endoplasmic reticulum
aml04151  PI3K-Akt signaling pathway
aml04156  Integrated stress response (ISR) signaling pathway
aml04210  Apoptosis
aml04211  Longevity regulating pathway
aml04261  Adrenergic signaling in cardiomyocytes
aml04668  TNF signaling pathway
aml04720  Long-term potentiation
aml04722  Neurotrophin signaling pathway
aml04725  Cholinergic synapse
aml04728  Dopaminergic synapse
aml04911  Insulin secretion
aml04912  GnRH signaling pathway
aml04915  Estrogen signaling pathway
aml04918  Thyroid hormone synthesis
aml04922  Glucagon signaling pathway
aml04925  Aldosterone synthesis and secretion
aml04926  Relaxin signaling pathway
aml04927  Cortisol synthesis and secretion
aml04928  Parathyroid hormone synthesis, secretion and action
aml04932  Non-alcoholic fatty liver disease
aml04934  Cushing syndrome
aml04935  Growth hormone synthesis, secretion and action
aml05010  Alzheimer disease
aml05012  Parkinson disease
aml05014  Amyotrophic lateral sclerosis
aml05020  Prion disease
aml05022  Pathways of neurodegeneration - multiple diseases
aml05030  Cocaine addiction
aml05031  Amphetamine addiction
aml05034  Alcoholism
aml05161  Hepatitis B
aml05163  Human cytomegalovirus infection
aml05166  Human T-cell leukemia virus 1 infection
aml05203  Viral carcinogenesis
aml05207  Chemical carcinogenesis - receptor activation
aml05215  Prostate cancer
aml05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:aml00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    100476284 (ATF4)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100476284 (ATF4)
   04668 TNF signaling pathway
    100476284 (ATF4)
   04022 cGMP-PKG signaling pathway
    100476284 (ATF4)
   04151 PI3K-Akt signaling pathway
    100476284 (ATF4)
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    100476284 (ATF4)
  09143 Cell growth and death
   04210 Apoptosis
    100476284 (ATF4)
   04156 Integrated stress response (ISR) signaling pathway
    100476284 (ATF4)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    100476284 (ATF4)
   04922 Glucagon signaling pathway
    100476284 (ATF4)
   04912 GnRH signaling pathway
    100476284 (ATF4)
   04915 Estrogen signaling pathway
    100476284 (ATF4)
   04926 Relaxin signaling pathway
    100476284 (ATF4)
   04935 Growth hormone synthesis, secretion and action
    100476284 (ATF4)
   04918 Thyroid hormone synthesis
    100476284 (ATF4)
   04928 Parathyroid hormone synthesis, secretion and action
    100476284 (ATF4)
   04925 Aldosterone synthesis and secretion
    100476284 (ATF4)
   04927 Cortisol synthesis and secretion
    100476284 (ATF4)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100476284 (ATF4)
  09156 Nervous system
   04725 Cholinergic synapse
    100476284 (ATF4)
   04728 Dopaminergic synapse
    100476284 (ATF4)
   04720 Long-term potentiation
    100476284 (ATF4)
   04722 Neurotrophin signaling pathway
    100476284 (ATF4)
  09149 Aging
   04211 Longevity regulating pathway
    100476284 (ATF4)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    100476284 (ATF4)
   05203 Viral carcinogenesis
    100476284 (ATF4)
  09162 Cancer: specific types
   05215 Prostate cancer
    100476284 (ATF4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100476284 (ATF4)
   05161 Hepatitis B
    100476284 (ATF4)
   05163 Human cytomegalovirus infection
    100476284 (ATF4)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    100476284 (ATF4)
   05012 Parkinson disease
    100476284 (ATF4)
   05014 Amyotrophic lateral sclerosis
    100476284 (ATF4)
   05020 Prion disease
    100476284 (ATF4)
   05022 Pathways of neurodegeneration - multiple diseases
    100476284 (ATF4)
  09165 Substance dependence
   05030 Cocaine addiction
    100476284 (ATF4)
   05031 Amphetamine addiction
    100476284 (ATF4)
   05034 Alcoholism
    100476284 (ATF4)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100476284 (ATF4)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    100476284 (ATF4)
   04934 Cushing syndrome
    100476284 (ATF4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:aml03000]
    100476284 (ATF4)
Transcription factors [BR:aml03000]
 Eukaryotic type
  Basic leucine zipper (bZIP)
   AP-1(-like) components, CRE-BP/ATF
    100476284 (ATF4)
SSDB
Motif
Pfam: bZIP_1 bZIP_2 CEP89 DUF4407 BNI5_helical MCU NOCA1_mid Asd-4 KIF21A AAA_13 Nop53 OVT1
Other DBs
NCBI-GeneID: 100476284
NCBI-ProteinID: XP_002914604
Ensembl: ENSAMEG00000010932
UniProt: D2GZL3
LinkDB
Position
15
AA seq 351 aa
MAEMSFLSSEVLVGDLMSPFDQSGLGAEESLGLLDDYLEVAKHFKPHGFSSDKAKAGSSE
WLAVDGLVSASDNGKEDAFSGTDWMVEKMDLKEFDFDSLFSIDDLETMPDELLATLDDTC
DLFDPLVQETNKEPPQTVNPIGHLPESLPKTDQIAPFTFLQPLPLSPGALSSTPDHSFSL
ELGSEVDISEGDRKSDSTAYITVIPQCIKEEDAPSDNDSGICMSPESYLGSPQHSPSTSR
GSPNRSLLSPGSHCGSARPKPYDPPGEKSAAKVKVEKLDKKLKKMEQNKTAATRYRQKKR
AEQEALTGECKELEKKNEALKERADSLAKEIQYLKDLIEEVRKAREKKRVP
NT seq 1056 nt   +upstreamnt  +downstreamnt
atggccgagatgagtttcctgagcagcgaggtgttggtgggggacttgatgtcccccttc
gaccagtcgggtttgggggctgaggagagcctgggtctcttagacgactacctggaggtg
gccaagcacttcaaacctcatgggttctccagcgacaaggctaaggcgggctcctccgaa
tggctggctgtggatgggttggtcagtgcctcagacaacggcaaggaggatgccttctcc
gggacagattggatggtggagaaaatggatctgaaggagtttgattttgattctctgttt
agtatagatgacctggaaaccatgccagatgagcttttggccacgttggatgacacgtgt
gatctctttgaccccctagtccaggagacgaataaggagcccccccagaccgtgaaccca
attggccatctcccagaaagtttaccaaaaacagaccagattgccccctttaccttcctg
caaccacttccactttccccaggggccctgtcctccactccagatcattcctttagttta
gagctaggcagtgaagtggatatttctgaaggagatagaaagtcagactctactgcctac
attaccgtgatccctcagtgcataaaggaggaggatgccccctcagataatgacagtggc
atctgtatgagtcctgagtcctatctggggtccccccagcatagcccctctacctccagg
ggctctccaaataggagcctgctgtctccaggttcccactgtggttctgcccgccccaaa
ccctatgaccctcctggagagaagtcggcagcaaaagtaaaggtcgagaaactagacaag
aagctgaaaaagatggagcagaacaagactgcagccactaggtaccgccagaagaagagg
gcagagcaggaggccctcactggcgagtgtaaagagctggaaaagaagaacgaggctctg
aaagagagggcagattctttggctaaggagatccagtatctgaaagatttgatagaagag
gttcgaaaggcaagggagaagaaaagggtcccctag

DBGET integrated database retrieval system