Ailuropoda melanoleuca (giant panda): 100476703
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Entry
100476703 CDS
T01329
Symbol
SHMT2
Name
(RefSeq) serine hydroxymethyltransferase, mitochondrial isoform X1
KO
K00600
glycine hydroxymethyltransferase [EC:
2.1.2.1
]
Organism
aml
Ailuropoda melanoleuca (giant panda)
Pathway
aml00260
Glycine, serine and threonine metabolism
aml00630
Glyoxylate and dicarboxylate metabolism
aml00670
One carbon pool by folate
aml01100
Metabolic pathways
aml01200
Carbon metabolism
aml01230
Biosynthesis of amino acids
aml01240
Biosynthesis of cofactors
aml01523
Antifolate resistance
aml04981
Folate transport and metabolism
Module
aml_M00141
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:
aml00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
100476703 (SHMT2)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
100476703 (SHMT2)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
100476703 (SHMT2)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
100476703 (SHMT2)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
100476703 (SHMT2)
Enzymes [BR:
aml01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.1 glycine hydroxymethyltransferase
100476703 (SHMT2)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
SHMT
Motif
Other DBs
NCBI-GeneID:
100476703
NCBI-ProteinID:
XP_002916051
Ensembl:
ENSAMEG00000004736
UniProt:
G1LDQ8
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All DBs
Position
15:34319710..34324741
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AA seq
504 aa
AA seq
DB search
MLPFSLLCATRPLQRCGQLVRMAIRCQHSEVAQTQTGEATRGWTGQESLSDSDPEMWELL
QREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQ
RRALEAFDLDPAQWGVNVQPYSGSPANLAAYTALLQPHDRIMGLDLPDGGHLTHGYMSDV
KRVSATSIFFESMPYKLNPKTGLIDYDQLALTARLFRPRLIIAGTSAYARLIDYARMREV
CDEVKAHLLADMAHISGLVAAKVIPSPFKHADVVTTTTHKTLRGARSGLIFYRKGMRAVD
PKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPVFREYALQVLKNARA
MADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAIT
PGGLRLGAPALTSRQFREDDFRRVVDFIDEGVSIGLEVKSKTAKLQDFKSFLLKDPETSH
RLADLRQRVEQFARAFPMPGFDEH
NT seq
1515 nt
NT seq
+upstream
nt +downstream
nt
atgctgcccttctctttgctctgcgcgactcggcctctgcagagatgtggtcagctggtc
aggatggccatccggtgccagcacagtgaggtagcccagacccagactggagaagcaacc
aggggctggacaggccaggagagtctgtcagacagtgaccctgagatgtgggagctgctg
cagagggagaaggacaggcagtgtcgtggcctggagctcattgcctcagagaacttctgc
agccgagctgcgctggaggccctggggtcctgtctgaacaacaagtactcggagggttat
cctggcaagagatactacggaggagcggaggtagtggatgaaattgagctgctgtgtcag
cgcagggccttggaggcctttgacctggatcccgcgcagtggggagtcaatgtgcagcca
tactcgggctctccggctaatctggccgcctacacggccctcctgcagccccatgaccga
atcatggggctggacttgcccgatgggggccatctgactcacggctacatgtccgatgtc
aagcgggtctcagccacgtccatcttctttgagtccatgccctataagctcaatcctaaa
accggcctcatcgactatgaccagctggcgctgactgcccggctcttccgcccgcggctc
attattgctggtaccagtgcctacgcgcgcctcattgactacgcccgcatgagagaggtg
tgtgatgaggtcaaggcacacctactggcagacatggcccacatcagtggcctggtggct
gccaaggtgattccctcacctttcaagcatgcggatgttgtcaccaccaccactcacaag
acccttcgaggggccaggtctggactcatcttctaccggaaggggatgcgggccgtggac
cccaagactggccgggagatcccgtacacatttgaggaccgaatcaactttgctgtgttc
ccatccctacagggggggccccacaaccatgccattgctgccgtggctgtggccctaaag
caggcctgcacccccgtgttccgggagtacgccctgcaggttctgaagaatgctcgggcc
atggctgatgccctgctagagcgaggctactcgcttgtgtctggtggcaccgacaaccac
ctagtgctcgtggatctgcggcccaagggcctggatggagctcgggctgagcgggtgctg
gaactggtgtccatcacagccaacaagaacacctgtcctggagaccgaagtgccatcaca
cctgggggcctgcggctcggggccccagccctgacctctcgacagttccgtgaggatgac
ttccggagagtcgtggactttatagatgaaggtgtcagcataggcttggaggtgaagagc
aagactgccaaactccaggatttcaaatccttcctgctcaaggacccagaaacaagtcat
cggctggctgacctcaggcaacgggtggagcagtttgccagggccttccccatgcctggt
tttgatgagcactga
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