KEGG   Ailuropoda melanoleuca (giant panda): 100476723
Entry
100476723         CDS       T01329                                 
Symbol
RHOA
Name
(RefSeq) transforming protein RhoA
  KO
K04513  Ras homolog gene family, member A
Organism
aml  Ailuropoda melanoleuca (giant panda)
Pathway
aml04014  Ras signaling pathway
aml04015  Rap1 signaling pathway
aml04022  cGMP-PKG signaling pathway
aml04024  cAMP signaling pathway
aml04062  Chemokine signaling pathway
aml04071  Sphingolipid signaling pathway
aml04072  Phospholipase D signaling pathway
aml04081  Hormone signaling
aml04144  Endocytosis
aml04150  mTOR signaling pathway
aml04270  Vascular smooth muscle contraction
aml04310  Wnt signaling pathway
aml04350  TGF-beta signaling pathway
aml04360  Axon guidance
aml04510  Focal adhesion
aml04520  Adherens junction
aml04530  Tight junction
aml04611  Platelet activation
aml04621  NOD-like receptor signaling pathway
aml04625  C-type lectin receptor signaling pathway
aml04660  T cell receptor signaling pathway
aml04670  Leukocyte transendothelial migration
aml04722  Neurotrophin signaling pathway
aml04810  Regulation of actin cytoskeleton
aml04921  Oxytocin signaling pathway
aml04928  Parathyroid hormone synthesis, secretion and action
aml04972  Pancreatic secretion
aml05100  Bacterial invasion of epithelial cells
aml05132  Salmonella infection
aml05133  Pertussis
aml05135  Yersinia infection
aml05152  Tuberculosis
aml05163  Human cytomegalovirus infection
aml05200  Pathways in cancer
aml05203  Viral carcinogenesis
aml05205  Proteoglycans in cancer
aml05206  MicroRNAs in cancer
aml05210  Colorectal cancer
aml05417  Lipid and atherosclerosis
aml05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:aml00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    100476723 (RHOA)
   04015 Rap1 signaling pathway
    100476723 (RHOA)
   04310 Wnt signaling pathway
    100476723 (RHOA)
   04350 TGF-beta signaling pathway
    100476723 (RHOA)
   04072 Phospholipase D signaling pathway
    100476723 (RHOA)
   04071 Sphingolipid signaling pathway
    100476723 (RHOA)
   04024 cAMP signaling pathway
    100476723 (RHOA)
   04022 cGMP-PKG signaling pathway
    100476723 (RHOA)
   04150 mTOR signaling pathway
    100476723 (RHOA)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    100476723 (RHOA)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    100476723 (RHOA)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    100476723 (RHOA)
   04660 T cell receptor signaling pathway
    100476723 (RHOA)
   04670 Leukocyte transendothelial migration
    100476723 (RHOA)
   04062 Chemokine signaling pathway
    100476723 (RHOA)
  09152 Endocrine system
   04921 Oxytocin signaling pathway
    100476723 (RHOA)
   04928 Parathyroid hormone synthesis, secretion and action
    100476723 (RHOA)
  09154 Digestive system
   04972 Pancreatic secretion
    100476723 (RHOA)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    100476723 (RHOA)
  09158 Development and regeneration
   04360 Axon guidance
    100476723 (RHOA)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100476723 (RHOA)
   05206 MicroRNAs in cancer
    100476723 (RHOA)
   05205 Proteoglycans in cancer
    100476723 (RHOA)
   05203 Viral carcinogenesis
    100476723 (RHOA)
  09162 Cancer: specific types
   05210 Colorectal cancer
    100476723 (RHOA)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    100476723 (RHOA)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    100476723 (RHOA)
   05133 Pertussis
    100476723 (RHOA)
   05152 Tuberculosis
    100476723 (RHOA)
   05100 Bacterial invasion of epithelial cells
    100476723 (RHOA)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100476723 (RHOA)
   05418 Fluid shear stress and atherosclerosis
    100476723 (RHOA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:aml04131]
    100476723 (RHOA)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:aml04147]
    100476723 (RHOA)
   04031 GTP-binding proteins [BR:aml04031]
    100476723 (RHOA)
Membrane trafficking [BR:aml04131]
 Endocytosis
  Lipid raft mediated endocytosis
   RhoA-dependent endocytosis
    100476723 (RHOA)
Exosome [BR:aml04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   100476723 (RHOA)
  Exosomal proteins of other body fluids (saliva and urine)
   100476723 (RHOA)
  Exosomal proteins of colorectal cancer cells
   100476723 (RHOA)
  Exosomal proteins of bladder cancer cells
   100476723 (RHOA)
GTP-binding proteins [BR:aml04031]
 Small (monomeric) G-proteins
  Rho Family
   RhoA/B/C [OT]
    100476723 (RHOA)
SSDB
Motif
Pfam: Ras Roc Arf GTP_EFTU Gtr1_RagA SRPRB VASP_tetra
Other DBs
NCBI-GeneID: 100476723
NCBI-ProteinID: XP_002920591
Ensembl: ENSAMEG00000012584
UniProt: D2HEV2
LinkDB
Position
4:complement(17956801..18012840)
AA seq 193 aa
MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDT
AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
LRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQ
ARRGKKKSGCLVL
NT seq 582 nt   +upstreamnt  +downstreamnt
atggctgccatccggaagaaactggtgattgttggtgatggagcctgtggcaagacttgt
ttgctcatcgtctttagcaaggaccagttcccagaggtgtatgtacccacagtgtttgag
aactatgtggcagatattgaagttgatgggaagcaggtagagttggctttgtgggataca
gctgggcaggaagattatgatcgcttgaggcctctctcctatccggacactgatgttata
ctgatgtgtttctccattgacagccctgatagtttagaaaacatcccagaaaaatggacc
ccggaagtcaagcacttctgtcccaacgtacccatcatcctggttgggaacaagaaggac
cttcggaatgatgagcacacacggcgggagctagccaagatgaagcaggagccagtgaaa
ccggaagaaggcagagatatggcaaacaggattggcgcttttgggtacatggagtgttca
gcaaagaccaaagatggagtgagggaggtttttgaaatggccacgagagctgctctgcaa
gccagacgtgggaagaaaaaatctgggtgccttgtcttgtga

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