Ailuropoda melanoleuca (giant panda): 100477326 Help Entry 100477326         CDS       T01329                                  Symbol PRKCA Name (RefSeq) protein kinase C alpha type   KO K02677   classical protein kinase C alpha type [EC:2.7.11.13] Organism aml  Ailuropoda melanoleuca (giant panda) Pathway aml01521   EGFR tyrosine kinase inhibitor resistance aml04010   MAPK signaling pathway aml04012   ErbB signaling pathway aml04014   Ras signaling pathway aml04015   Rap1 signaling pathway aml04020   Calcium signaling pathway aml04066   HIF-1 signaling pathway aml04070   Phosphatidylinositol signaling system aml04071   Sphingolipid signaling pathway aml04072   Phospholipase D signaling pathway aml04082   Neuroactive ligand signaling aml04150   mTOR signaling pathway aml04151   PI3K-Akt signaling pathway aml04261   Adrenergic signaling in cardiomyocytes aml04270   Vascular smooth muscle contraction aml04310   Wnt signaling pathway aml04360   Axon guidance aml04370   VEGF signaling pathway aml04510   Focal adhesion aml04540   Gap junction aml04613   Neutrophil extracellular trap formation aml04650   Natural killer cell mediated cytotoxicity aml04664   Fc epsilon RI signaling pathway aml04666   Fc gamma R-mediated phagocytosis aml04670   Leukocyte transendothelial migration aml04713   Circadian entrainment aml04720   Long-term potentiation aml04723   Retrograde endocannabinoid signaling aml04724   Glutamatergic synapse aml04725   Cholinergic synapse aml04726   Serotonergic synapse aml04727   GABAergic synapse aml04728   Dopaminergic synapse aml04730   Long-term depression aml04750   Inflammatory mediator regulation of TRP channels aml04911   Insulin secretion aml04912   GnRH signaling pathway aml04916   Melanogenesis aml04918   Thyroid hormone synthesis aml04919   Thyroid hormone signaling pathway aml04921   Oxytocin signaling pathway aml04925   Aldosterone synthesis and secretion aml04926   Relaxin signaling pathway aml04928   Parathyroid hormone synthesis, secretion and action aml04929   GnRH secretion aml04933   AGE-RAGE signaling pathway in diabetic complications aml04935   Growth hormone synthesis, secretion and action aml04960   Aldosterone-regulated sodium reabsorption aml04961   Endocrine and other factor-regulated calcium reabsorption aml04970   Salivary secretion aml04971   Gastric acid secretion aml04972   Pancreatic secretion aml05017   Spinocerebellar ataxia aml05022   Pathways of neurodegeneration - multiple diseases aml05031   Amphetamine addiction aml05032   Morphine addiction aml05143   African trypanosomiasis aml05146   Amoebiasis aml05161   Hepatitis B aml05163   Human cytomegalovirus infection aml05164   Influenza A aml05170   Human immunodeficiency virus 1 infection aml05171   Coronavirus disease - COVID-19 aml05200   Pathways in cancer aml05205   Proteoglycans in cancer aml05206   MicroRNAs in cancer aml05207   Chemical carcinogenesis - receptor activation aml05214   Glioma aml05223   Non-small cell lung cancer aml05225   Hepatocellular carcinoma aml05231   Choline metabolism in cancer aml05415   Diabetic cardiomyopathy aml05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:aml00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     100477326 (PRKCA)    04012 ErbB signaling pathway     100477326 (PRKCA)    04014 Ras signaling pathway     100477326 (PRKCA)    04015 Rap1 signaling pathway     100477326 (PRKCA)    04310 Wnt signaling pathway     100477326 (PRKCA)    04370 VEGF signaling pathway     100477326 (PRKCA)    04066 HIF-1 signaling pathway     100477326 (PRKCA)    04020 Calcium signaling pathway     100477326 (PRKCA)    04070 Phosphatidylinositol signaling system     100477326 (PRKCA)    04072 Phospholipase D signaling pathway     100477326 (PRKCA)    04071 Sphingolipid signaling pathway     100477326 (PRKCA)    04151 PI3K-Akt signaling pathway     100477326 (PRKCA)    04150 mTOR signaling pathway     100477326 (PRKCA)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     100477326 (PRKCA)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     100477326 (PRKCA)    04540 Gap junction     100477326 (PRKCA)  09150 Organismal Systems   09151 Immune system    04613 Neutrophil extracellular trap formation     100477326 (PRKCA)    04650 Natural killer cell mediated cytotoxicity     100477326 (PRKCA)    04664 Fc epsilon RI signaling pathway     100477326 (PRKCA)    04666 Fc gamma R-mediated phagocytosis     100477326 (PRKCA)    04670 Leukocyte transendothelial migration     100477326 (PRKCA)   09152 Endocrine system    04911 Insulin secretion     100477326 (PRKCA)    04929 GnRH secretion     100477326 (PRKCA)    04912 GnRH signaling pathway     100477326 (PRKCA)    04921 Oxytocin signaling pathway     100477326 (PRKCA)    04926 Relaxin signaling pathway     100477326 (PRKCA)    04935 Growth hormone synthesis, secretion and action     100477326 (PRKCA)    04918 Thyroid hormone synthesis     100477326 (PRKCA)    04919 Thyroid hormone signaling pathway     100477326 (PRKCA)    04928 Parathyroid hormone synthesis, secretion and action     100477326 (PRKCA)    04916 Melanogenesis     100477326 (PRKCA)    04925 Aldosterone synthesis and secretion     100477326 (PRKCA)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     100477326 (PRKCA)    04270 Vascular smooth muscle contraction     100477326 (PRKCA)   09154 Digestive system    04970 Salivary secretion     100477326 (PRKCA)    04971 Gastric acid secretion     100477326 (PRKCA)    04972 Pancreatic secretion     100477326 (PRKCA)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     100477326 (PRKCA)    04961 Endocrine and other factor-regulated calcium reabsorption     100477326 (PRKCA)   09156 Nervous system    04724 Glutamatergic synapse     100477326 (PRKCA)    04727 GABAergic synapse     100477326 (PRKCA)    04725 Cholinergic synapse     100477326 (PRKCA)    04728 Dopaminergic synapse     100477326 (PRKCA)    04726 Serotonergic synapse     100477326 (PRKCA)    04720 Long-term potentiation     100477326 (PRKCA)    04730 Long-term depression     100477326 (PRKCA)    04723 Retrograde endocannabinoid signaling     100477326 (PRKCA)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     100477326 (PRKCA)   09158 Development and regeneration    04360 Axon guidance     100477326 (PRKCA)   09159 Environmental adaptation    04713 Circadian entrainment     100477326 (PRKCA)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100477326 (PRKCA)    05206 MicroRNAs in cancer     100477326 (PRKCA)    05205 Proteoglycans in cancer     100477326 (PRKCA)    05207 Chemical carcinogenesis - receptor activation     100477326 (PRKCA)    05231 Choline metabolism in cancer     100477326 (PRKCA)   09162 Cancer: specific types    05225 Hepatocellular carcinoma     100477326 (PRKCA)    05214 Glioma     100477326 (PRKCA)    05223 Non-small cell lung cancer     100477326 (PRKCA)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     100477326 (PRKCA)    05161 Hepatitis B     100477326 (PRKCA)    05171 Coronavirus disease - COVID-19     100477326 (PRKCA)    05164 Influenza A     100477326 (PRKCA)    05163 Human cytomegalovirus infection     100477326 (PRKCA)   09174 Infectious disease: parasitic    05146 Amoebiasis     100477326 (PRKCA)    05143 African trypanosomiasis     100477326 (PRKCA)   09164 Neurodegenerative disease    05017 Spinocerebellar ataxia     100477326 (PRKCA)    05022 Pathways of neurodegeneration - multiple diseases     100477326 (PRKCA)   09165 Substance dependence    05031 Amphetamine addiction     100477326 (PRKCA)    05032 Morphine addiction     100477326 (PRKCA)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     100477326 (PRKCA)    05415 Diabetic cardiomyopathy     100477326 (PRKCA)   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     100477326 (PRKCA)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     100477326 (PRKCA)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:aml01001]     100477326 (PRKCA)   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:aml04131]     100477326 (PRKCA) Enzymes [BR:aml01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.13  protein kinase C      100477326 (PRKCA) Protein kinases [BR:aml01001]  Serine/threonine kinases: AGC group   PKC family [OT]    100477326 (PRKCA) Membrane trafficking [BR:aml04131]  Endocytosis   Lipid raft mediated endocytosis    Caveolin-mediated endocytosis     100477326 (PRKCA) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr C1_1 C2 Pkinase_C C1_2 ABC1 Motif Other DBs NCBI-GeneID:  100477326 NCBI-ProteinID:  XP_002921765 Ensembl:  ENSAMEG00000011747 UniProt:  G1LZD5 LinkDB All DBs Position 13:complement(32670770..33077139) Genome browser AA seq 672 aa AA seqDB search MADVFPANDSTASQDVANRFARKGALRQKNVHEVKDHKFIARFFKQPTFCSHCTDFIWGF GKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPDTDDPRSKHKFKIHTYGSPTFCDHCGS LLYGLIHQGMKCDTCDMNVHKQCVINVPSLCGMDHTEKRGRIYLKAEVTDEKLHVTVRDA KNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQWNESFTFKLKPSDKDRRL SVEIWDWDRTTRNDFMGSLSFGVSELMKMPASGWYKLLNQEEGEYYNVPIPEGDEEGNVE LRQKFEKAKLGPAGNKVISPSEDRRQPSNNLDRVKLTDFNFLMVLGKGSFGKVMLADRKG TEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDKPPFLTQLHSCFQTVDRLYFVMEYV NGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIA DFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDG EDEDELFQSIMEHNVSYPKSLSKEAVSICKGLMTKHPGKRLGCGPEGERDVREHAFFRRI DWEKLENREIQPPFKPKVCGKGAENFDKFFTRGQPVLTPPDQLVIANIDQSDFEGFSYVN PQFVHPILQSAV NT seq 2019 nt NT seq  +upstreamnt  +downstreamnt atggctgacgttttcccggccaacgactccacggcgtctcaggacgtggccaaccgcttc gcccgcaaaggggcgctgaggcagaagaacgtgcatgaggtgaaggaccacaaattcatc gcccgcttcttcaagcagcccaccttctgcagccactgcaccgacttcatctgggggttt gggaaacaaggcttccagtgccaagtttgctgttttgtggttcacaagaggtgccatgaa tttgtcactttttcttgtccgggtgcggataagggacccgacaccgacgacccaagaagc aagcacaagtttaaaatccacacttatggaagccccaccttctgtgatcactgtgggtcc ttgctgtatggacttatccatcaagggatgaaatgtgacacctgcgacatgaacgtgcac aaacagtgcgtgatcaacgtgcccagcctctgcgggatggaccacacggagaagaggggc cggatctacctgaaggcggaggtcaccgacgagaagctccacgtcaccgtacgagatgca aaaaatctaattcctatggatccaaatgggctttcagatccttatgtgaagctgaaactt attcctgatcccaagaatgagagcaaacagaaaaccaaaaccatccgctccacactgaac ccccagtggaatgagtcctttacattcaaattaaaaccttcggataaagaccgacggctg tccgtagaaatctgggactgggatcgaacaactaggaatgatttcatggggtccctctcc tttggagtctcggagctgatgaagatgccagccagcggatggtacaagctgcttaaccaa gaggaaggtgagtactacaacgtgcccattccggaaggggacgaagaaggcaacgtggag ctcaggcagaaattcgagaaagccaagcttggcccagctgggaacaaagtaatcagtcct tcagaagacagaagacaaccttccaacaacctggacagagtgaaactcaccgacttcaat ttcctcatggtgctggggaaggggagttttggaaaggtgatgcttgctgaccggaagggc acagaggaactgtatgctatcaaaatcctgaagaaggatgtggtgattcaggatgacgac gtggagtgcaccatggtggagaagcgagtcctagccctcctggacaagccgccgttcctg acacagctacactcctgcttccagacagtggatcggctgtacttcgtcatggaatacgtc aatggcggggacctcatgtaccacattcagcaagtaggaaaatttaaggaaccacaagca gtattttatgcggcagagatttccattggattgttctttcttcataaaagaggaatcatt tacagggatctgaagttagataatgtcatgctggattcagaagggcatatcaagattgcc gattttgggatgtgcaaggaacacatgatggacggagtcacaaccaggaccttctgtggg acgccagattacatcgccccagagataatcgcctatcagccgtatggaaaatctgtggac tggtgggcctatggcgtcctgttgtatgaaatgctagctgggcagcctccctttgatggt gaagatgaagacgagctgtttcagtccataatggagcataacgtttcttatcccaagtcc ttgtccaaggaggccgtttccatctgcaagggactgatgaccaaacacccaggcaagcgg ctgggttgcgggccggagggggagagggacgtgcgggaacatgccttcttccggaggatc gactgggagaaactcgagaacagggagatccagccacccttcaagcccaaagtgtgtggc aaaggcgcagaaaactttgacaagttcttcacgcgagggcagcctgtcttgacaccacct gatcagctggtcattgctaacatagaccagtctgatttcgaggggttctcgtatgtcaac ccccagtttgtgcaccccatcttacagagcgcagtatga

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