KEGG   Ailuropoda melanoleuca (giant panda): 100479318
Entry
100479318         CDS       T01329                                 
Name
(RefSeq) LOW QUALITY PROTEIN: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1
  KO
K05860  phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
Organism
aml  Ailuropoda melanoleuca (giant panda)
Pathway
aml00562  Inositol phosphate metabolism
aml01100  Metabolic pathways
aml04014  Ras signaling pathway
aml04015  Rap1 signaling pathway
aml04020  Calcium signaling pathway
aml04024  cAMP signaling pathway
aml04070  Phosphatidylinositol signaling system
aml04919  Thyroid hormone signaling pathway
aml04933  AGE-RAGE signaling pathway in diabetic complications
aml05205  Proteoglycans in cancer
Module
aml_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:aml00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    100479318
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    100479318
   04015 Rap1 signaling pathway
    100479318
   04020 Calcium signaling pathway
    100479318
   04070 Phosphatidylinositol signaling system
    100479318
   04024 cAMP signaling pathway
    100479318
 09150 Organismal Systems
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    100479318
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    100479318
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    100479318
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:aml04131]
    100479318
Enzymes [BR:aml01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     100479318
Membrane trafficking [BR:aml04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    100479318
 Endocytosis
  Macropinocytosis
   Phospholipase C
    100479318
SSDB
Motif
Pfam: PI-PLC-X PI-PLC-Y RasGEF RA C2 EF-hand_like GDPD
Other DBs
NCBI-GeneID: 100479318
NCBI-ProteinID: XP_034519502
Ensembl: ENSAMEG00000013653
LinkDB
Position
6:97035398..97136067
AA seq 1769 aa
MVDLAWCRVHHGAVCSLQLLLPASAWVTGTPPAQLPWTMNSVFRPHSPSGLGNELAPGFS
TVAEPVQLLGHVSSWVTWLILTAGSMEEKREVFSYLVHVAKCCWNMGNYNAVMEFLAGLR
SRKVLKMWQFMDQSDLETMRSLKDAMAQHESSCEYRKVITRALHIPGCKVVPFCGVFLKE
LCEVLDGASGLMKLCPRYNSQEETLEFVADYSGQDNFLQRVGHNGLKNSEKESTVNSIFQ
IIRSCSRSLEAEDEDSASEGNSSRKNSLRDKARWQFIIGDLLDSENDLCEQSKEWDSHGS
EEPQKAFDHGTELIPWYVLSIRADVHQFLLQGATVIHYDQDTHLSARCFLQLQPDNSTLT
WVKPTTASPASAKAKLGVLSNTAEPGKFPLLGNAGLSGLAEGVLDLFSAKAVYMGHPSID
IHTVCVQNKLGSMFLSETGVTLLYGLQTTDNRLLHFVAPKHTAKMLFSGLLELTRAVRKM
RKFPDQRQQWLRKQYVSLYQEDGRYEGPTLAHAVELFGGRRWSTRNPSPGTSAKSTEKPS
VQRNNTLGISTTKKKKKILIRGESGEAADDEMATRKAKMHRESRSRSGSDPQDMNEQEES
ETNAIMSLPNTLPSRRAHSLTTAGSPNLSAGTSSPIRPVSSPVLSSSNKSPSSPWSSSSW
HGRIKGGMKGFQSFMVSDSNMSFVEFVELFKSFSVRSRKDLKDLFDVYAVPCNRAGSESA
PLYTNLTIDENTSDLQPDLDLLTRNVSDLGLFIKSKQQLSDNQRQISDAIAAASIVTNGT
GVESTSLGIFGVGILQLNDFLVNCQGEHCTYDEILSIIQKFEPSVSMCHQGLLSFEGFAR
FLMDKDNFASKNDESQENIKDLQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQG
CRSVELDCWDGDDGMPIIYHGHTLTTKIPFKEVVEAIDRSAFINSDLPIIISIENHCSLP
QQRKMAEIFKTVFGEKLVAKFLFESDFSDDPMLPSPDQLRRKVLLKNKKLKAHQTPVDIL
KQKAHQLASMQAQAYNGGNANPPPANNEEEEDEEDEYDYDYESLSDDNILEDRPENKSCN
DKLQFEYNEEIPKRIKKADNSACNKGKVYDMELGEEFYLPQNKKESRQIAPELSDLVIYC
QAVKFPGLSTLNASGSSRGKERKSRKSIFGNNPGRMSPGETAAFNKASGKSSYEGMRQAW
EESSSPLNPTTSLSAIIRTPKCYHISSLNENAAKRLCRRYSQKLIQHTACQLLRTYPAAT
RIDXSNPNPLMFWLHGIQLVALNYQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPM
YQKFSPLERDLDNMEPAIYSLTIVSGQNVCPSSSTGSPCIEVDVLGMPLDSCHFRTKPIH
RNTLNPMWNEQFLFRVHFEDLIFLRFAVVENNSSAVTAQRIIPLKALKRGYRHLQLRNLH
NEVLEISSLFINSRRMEENSSSSAVPASLMFNTEERKCLQTHRVTVHGVPGPEPFTVFSI
NGGTKAKQLLQQILTTEQDTKPIVTDYFLMEEKYFISKEKNECRKQPFQRVIGPEEEIMQ
ILSSWFPEEGYVGRIVLKTQQENLEERSILQDDKEVILSSEEESFFVQVHDVSPEQPRTV
IKAPRVSTAQDVIQQTLCKAKYSYSILSNPNPSDYVLLEEVVKDATKKSSTPKSSQRVLL
DQECVFQAQSKWKGAGKFILKLKEQVQASREDKRKGISFASEFKKFTKSTKQPRGLTSPS
QVLASEGVQSKEEKLVGSLPSSDTTDYRQ
NT seq 5310 nt   +upstreamnt  +downstreamnt
atggtcgacttggcctggtgccgtgttcaccacggtgctgtctgctccctccagcttctc
ctgcctgcttcggcgtgggtcacagggacacccccagctcagttgccatggaccatgaac
tctgtgttcaggcctcactctccctcaggcctgggaaatgagctggccccaggtttcagc
actgttgctgaaccagtgcagctcctgggccatgtgagctcctgggtgacgtggttgatc
ctcacggcgggctccatggaggagaagcgagaagtcttctcctatttggtgcacgtggcc
aaatgctgctggaacatgggcaactacaatgctgtcatggagttcttggctggcctcagg
tcaagaaaagttttgaaaatgtggcagtttatggaccagtctgacctggagaccatgagg
agcctgaaggatgccatggctcagcacgaatcttcctgcgagtacaggaaggtgatcacg
cgggccctgcacatacccggctgtaaggtggtcccattctgtggggtgtttctgaaggag
ctctgtgaagtactggacggagcctctggcctcatgaagctttgcccgaggtacaattct
caagaagaaactctagagtttgtagccgattacagtggacaagataatttcttacaacga
gtgggacataatggcttgaagaattcagagaaggagtccaccgtcaacagcatctttcag
atcatcaggagctgcagccgaagtctggaggccgaggacgaggacagcgccagtgagggc
aacagctctaggaaaaattccttaagggataaagcgcggtggcagtttataattggagat
ttgctggattccgaaaatgacctctgtgagcagtcgaaagaatgggactctcatggatca
gaagagccacagaaggcctttgaccacgggacagagctgatcccgtggtacgtgctgtcc
atccgagctgatgtgcaccagttcctgctgcagggggccactgtcatccactacgaccag
gacacgcacctgtcggcccgctgcttcctccagctccagcctgacaacagcaccttgacc
tgggtaaagcccaccactgcctccccagccagtgctaaagcaaaacttggtgtgcttagt
aacacggctgagcctggcaaattcccgttactgggcaatgctggattaagtggcctggcg
gagggggtcttggatctgttttcagcaaaggctgtgtacatgggacaccctagcatcgat
atacacactgtgtgtgttcagaacaaactgggtagcatgtttctctcagagactggtgtg
acactgctctatgggctgcagaccacggacaataggttattgcactttgtggcacccaag
cacaccgctaagatgctcttcagtggattgctagaactcacgagggccgtgaggaagatg
aggaagttccctgaccagagacagcagtggctgcggaaacagtacgtcagcctctatcag
gaggatggacggtacgaaggcccaactttggctcacgccgtggagctgtttggtggccgg
cgatggagtacacgcaaccccagccctgggacatccgcgaagagtactgagaagcccagt
gtgcagagaaacaacaccttgggcataagcaccaccaagaaaaagaagaaaatccttata
aggggtgagagtggagaggcggctgacgacgagatggccacgcggaaggccaaaatgcac
agggagagtcgcagccggagtggttccgaccctcaagacatgaatgagcaagaagaatcc
gagacgaatgccatcatgagccttcctaacactctgccttccagaagagcccactctttg
accacggctgggtcccctaacttgtctgctgggacatcatctcccatcaggccagtgtcc
tcccctgtgctgtcttcttcaaacaagagcccgtccagtccttggagcagcagcagctgg
cacgggaggatcaaaggaggaatgaagggttttcagagcttcatggtttcagacagtaac
atgagttttgttgaatttgttgagctgttcaaatcattcagcgtgaggagccgcaaggac
ctgaaggatctcttcgacgtctacgccgtgccctgcaaccgagccggctccgagtcagcc
cccctctacaccaacctaaccattgacgaaaacaccagcgaccttcagcctgacctagat
ttattgaccagaaatgtctcagacttggggttgttcattaagagtaaacagcagctgtca
gacaaccagaggcagatatctgatgccattgctgctgcaagtatcgtgacaaatggcact
ggggtcgagagcacatctctgggcatctttggggttggcatactccagctcaatgacttc
ctcgtcaactgccagggagagcactgcacttatgatgaaatcctcagcatcatccagaag
ttcgagcctagcgttagtatgtgtcatcagggcctactgtcatttgagggatttgcaagg
tttctgatggataaagataattttgcctccaaaaatgacgagtcgcaggaaaacattaaa
gacttgcagctgcccctctcctactattacattgaatcttcacacaatacctacctcaca
gggcaccagctcaaaggagagtcctcagtggaactctacagccaggtcctcctgcaaggc
tgcagaagcgtagagttggactgctgggacggagatgatgggatgcccattatctaccac
ggacacacactgacaaccaagatccccttcaaggaggtggttgaagccattgaccgcagt
gccttcatcaactctgacctgcccatcatcatatcaattgagaaccactgctcattgcct
cagcaacgaaaaatggcagaaattttcaagactgtgtttggagaaaaactggtggctaaa
ttcctgtttgagagcgatttctcagatgatccaatgcttccctcacctgaccaacttagg
aggaaagtgcttcttaaaaataagaagctcaaagcccaccagacaccagtggatatctta
aagcaaaaggctcatcagttagcatccatgcaagctcaggcttataatggggggaatgcc
aaccccccacctgccaataacgaggaagaggaggatgaagaagacgaatatgattatgac
tatgaatccctgtctgatgacaatattctagaagacagacctgaaaataaatcatgtaat
gacaagcttcagttcgagtataatgaagaaatccccaagaggataaagaaagccgataac
tctgcttgcaacaaaggaaaggtttatgacatggaactgggagaagaattttatcttcct
cagaataaaaaggaaagtagacagattgcaccagagctttctgaccttgtcatctattgc
caagcggtaaaatttccaggcctgtcaactctaaatgcatctggctctagcagaggaaaa
gaaaggaaaagcaggaagtccatttttggcaacaatccgggcagaatgagccctggggag
acagcagcgtttaacaaagcatctggaaaaagttcctatgaaggaatgcgacaggcctgg
gaggaatcttcttcccccctcaacccaaccacatccctcagcgctatcattagaactccc
aaatgttaccatatttcatcgctgaatgaaaatgccgccaaacgtctgtgtcgcaggtat
tctcagaaactgatccagcacaccgcctgtcagctgctgaggacttacccggctgccacc
cgcatcgacnnttccaaccccaatcccctcatgttctggctccatgggatacagctcgtg
gcgctcaactaccagacagatgatctccccttacatttaaatgctgccatgtttgaggcc
aacggtggctgtggttatgttctgaaacccccagttctgtgggacaagaactgtcccatg
tatcagaagttttcacccttggaaagagacctggacaacatggagcctgccatctattcc
ttaactattgtctctggtcaaaacgtgtgtccgagcagcagcacggggagcccgtgtatc
gaagtcgacgtgctgggcatgcccttggacagctgccacttccgcacaaagcccatccac
cggaacactctgaaccccatgtggaatgaacagtttctcttccgggtgcactttgaagac
ctcatatttcttcgttttgcagtcgtggaaaataacagctcagccgtaaccgctcagaga
atcatcccgctcaaggctttgaaacgaggatatcggcatcttcagctacgaaacctccac
aatgaagtcttggaaatctccagtttattcataaacagcagaaggatggaagaaaattcc
tccagcagtgccgtgccggcctctttgatgtttaatacagaagaaagaaaatgtttgcag
actcacagagttacagtgcatggggtcccaggtccagagccgtttactgttttctccata
aacgggggcaccaaggcaaagcagcttctccaacaaattctgactactgaacaggacacc
aaacctattgtcacagactattttttgatggaagaaaaatattttatatctaaagaaaag
aatgaatgcaggaaacaaccattccagagagtcatcggtccagaagaagagatcatgcag
attttaagcagctggtttcccgaggaaggatatgttggcaggattgtcttaaaaacccag
caggaaaacctagaagagagaagcattcttcaagatgacaaagaggtgatcttgagctca
gaggaggagagtttctttgttcaagttcacgacgtttctccagagcaacctcgaacagtc
atcaaagcgccccgtgtcagcactgcgcaggacgtcattcagcagaccttatgcaaagcc
aaatattcctatagcatcctgagcaaccccaacccgagtgactatgtgcttctggaggag
gtggtgaaagatgctaccaagaagtcttccaccccgaagtcctcccagcgagtccttttg
gatcaggagtgtgtgtttcaagcccaaagcaagtggaagggcgcaggaaaattcatcctt
aagctaaaggagcaggtacaggcatcccgagaagacaaaaggaaaggcatttcttttgca
agtgaattcaagaagttcactaagtcaactaaacagccccgaggactcacgtcaccttct
caggtcttggcctcagaaggtgtccaaagcaaggaggagaaactggtgggcagcttgcct
tccagtgacaccacagactaccgacaataa

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