| Entry |
|
|---|
| Symbol |
ATM
|
|---|
| Name |
(RefSeq) serine-protein kinase ATM isoform X1
|
|---|
| KO |
|
|---|
| Organism |
aml Ailuropoda melanoleuca (giant panda)
|
|---|
| Pathway |
| aml05166 | Human T-cell leukemia virus 1 infection |
| aml05170 | Human immunodeficiency virus 1 infection |
| aml05202 | Transcriptional misregulation in cancer |
|
|---|
| Brite |
KEGG Orthology (KO) [BR:aml00001]
09120 Genetic Information Processing
09124 Replication and repair
03440 Homologous recombination
100480638 (ATM)
09130 Environmental Information Processing
09132 Signal transduction
04064 NF-kappa B signaling pathway
100480638 (ATM)
04068 FoxO signaling pathway
100480638 (ATM)
09140 Cellular Processes
09143 Cell growth and death
04110 Cell cycle
100480638 (ATM)
04210 Apoptosis
100480638 (ATM)
04115 p53 signaling pathway
100480638 (ATM)
04218 Cellular senescence
100480638 (ATM)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
100480638 (ATM)
05206 MicroRNAs in cancer
100480638 (ATM)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
100480638 (ATM)
05170 Human immunodeficiency virus 1 infection
100480638 (ATM)
05165 Human papillomavirus infection
100480638 (ATM)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
100480638 (ATM)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:aml01001]
100480638 (ATM)
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:aml03032]
100480638 (ATM)
03036 Chromosome and associated proteins [BR:aml03036]
100480638 (ATM)
03400 DNA repair and recombination proteins [BR:aml03400]
100480638 (ATM)
Enzymes [BR:aml01000]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
100480638 (ATM)
Protein kinases [BR:aml01001]
Serine/threonine kinases: Other
PIKK family [OT]
100480638 (ATM)
DNA replication proteins [BR:aml03032]
Eukaryotic type
DNA Replication Termination Factors
Other termination factors
100480638 (ATM)
Chromosome and associated proteins [BR:aml03036]
Eukaryotic type
Meiosis-specific proteins
DSB formation-related proteins
100480638 (ATM)
DNA repair and recombination proteins [BR:aml03400]
Eukaryotic type
Check point factors
Other check point factors
100480638 (ATM)
|
|---|
| SSDB |
|
|---|
| Motif |
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| Position |
8:5408454..5534645
|
|---|
| AA seq |
3058 aa
MSLALNDLLICCRHLEHDRATERRKEVEKFKRLIRDPETVQHLDRHSDSKQSKYLNWDAV
FRFLQKYVQKETECLRTAKPSVSASTQATRQKKMQEISSLVKYFIKCANKRAPRLKCQEL
LNYIMDTVKDSSNGPVYGADCSNILLKDILSVRKYWCEISQQQWLELFSVYFGLYLKPAQ
DINRVLVARIIHAVTKGCCSQTDGLNAKFLDFFSKAIQHARQEKSSAGLNHILAAFIIFL
KTLAVNFRIRVCQLGDEILPTLLYIWTQHRLNDSLKEVIIELFQLQIYVHHPKGAKTQEK
GAYESSKWKSILYNLYDLLINEISHIGSRGKYSSGSRNVAVKENLIELMADICHQIFNED
TRSLEISQSYTTTQRELNDYSTPCKKKKIELGWEVIKDHLQKSQSDFDLVPWLQITTQLI
SKYPSSLPNCELSPLLVILYQLLPQHRHGERTPYVLRCLTEVALCQGKKSNLEVSQKSDL
LKFWIKIWSLTFRGISSEQIQAENFGLLGAIIQGSLIEVDREFWKLFTGSACRPSCPAVC
CLTLAMTVCVVPETVKTGVEHSLCEVNRSCSLKELIMKWLLLYHLEDDFEDGTELPPVLH
SNFPHLAVEKILVSLTMKNCKAAMNFLQRVPECEQHQKDQEEPPFSEVEELFLQTTFDKM
GFLTIVKECAVEKHQSTVGFSVHQNLKESLDRYLLGLSEQLLHNYSSETTNAETLIRCSS
LLVGVLGCYCYVGVIAEEEAYRSELFQKAKSLMQCAGESITLFKSKTNEESRIASLRNMM
NLCTSCLCNCTKPSPNKIASRFFLRLLTSKLMNDIADICRSLASFIRKPSDFGEVESLED
EADENLMEVEDQSSMTLFSDYPPGSSSDAPMSGDGQSTFGAMNPLAEEHLSKQDLLFLDM
LKFLCVCVTTAQTSPVSFRAADIRRKLLMLIDTSMLDPTKSLHLHMYLLLLKELPGEEYP
LPMEEVVELLKPLSNVCSLYRRDQDVCKTLLNHFVHIVRNLCQGDMDAENARDAQGQFLT
VIGAFWHLAKEGKCTFSVRMALVKCLKTLLETDPYSKWAILNVMGKDFPVNEVFPHFLAD
NHHQVSMLAAESINRLFQDMKHRGSSTLWKALPLKLQQTAFENAYLQAQEGMREVSHRAK
NPELLDEIYNRKSVLLMTIAVVLCCSPVCEKQALFALCKSVKENGLEPHLVKKVLGKVSE
TFGYRRLEDFMASHLDYLVLEWLNLQDTEHSLYSFPFILLNYTTVEDFYRSCYKVLIPHL
VIRSRFDEVKSIANQIEEDWKSLLTHCFPKILVNILPYFAYEGTGDSGMAQQRETATKVY
DMLKDENLLGKQIDHLFLSNLPEIVVELLMTLHEPAAAGTSQSTDLCDFSGDLDPAPNPP
HFPSHVIKATFAYISNCHKTKLKSILEILSKSPDSYQKILLAICEQAAETNNVYKKHRIL
KIYHLFVTLLLKDIKSALGGAWAFVLRDVIYTLIHYINKKPSRFVDVSSRSFSLCCDLLS
RVCHTAVTYCKDALENHLHVIVGTLIPLVDDQMEVQGQVLDLLKYLVIDNKDNENLYMTI
KLLDPFPDHDVFKDLRITQQKIKYSKGPFSLLEEINHFLSVSAYDALPLTRLEGLKDLRR
QLAQHKDQMAGLMRASKDNPQDGIMVKLIVSLLQLCKMAVNHTGEIEVLEAVGSCLGEVG
PVDFSTIALQHSGDTSSTKAPELFKDKELQWTFITLTYLNNTLVEDCVKVRSAAATCLKS
ILATKTGHSFWEIYKTTPDPMLIYLQPFRTSKKKFLEVPRLEKESPLEGLDDMSLWIPQN
ENHDIWIKRLTCAFLDSGGTKSEILRLLKPMCEVKTDFCQAVLPYLIHDILLQDTEESWR
NLLSAHIQGFFTNCFRHSSPPSRSTTPANLDSESEHLFRCCVDKKSQRTMLAVVDYMRRQ
KRPSLGTVFDDAFWLELNYLEVAKVAQSCAAHFTALLYAEIYADKKSMEDQDKRSLTFEE
ASQSTAISSLSEKSKEETGISLQDLLLEIYRSIGEPDSLYGCGGGKLLQPLTRLRTYEHE
AMWGKALVTYDLETAISPSTRQAGIIQALQNLGLCHILSVYLKGLDHENKERCAELQELH
YQAAWRNMQWDHCLSVNKGVEGTNYHESLYNAVQSLRDREFSTFYESLRYARVKEVEELC
KGGLESVYSLYPTLSRLQAIGELENIGELLARSGTDSRQPSEVYAKWRKHSQLLKDSDFS
FQEPIMALRTVILEILMEKEMENSQKECFRDILTKHLVELSILARTVKNTQLPERAMFQI
KQYNPASCGVSEWQLEEAQVFWAKKEQSLALSILKQMIKKLDASCAENDPDLRLIYAECL
RVCGTWLAETCLENPAVIMQTYLEKAVEVARNYDGESSDELKNGKMKAFLSLARFSDTQY
QRIENYMKSSEFENKQALLKRAKEEVGLLREHKIQTNRYTVKVQRELELDECALRALKED
RKRFLCKAVENYISCLLSGEGHDMWIFRLCSLWLENSGVSEVNGMMKIDGMKIPSYKFLP
LMYQLAARMGTKMMGGLGFHEVLNNLISRIAMDHPHHTLFIILALANANKDEFLTKPEAA
GRNRITKNAPKQSSPLDEDRTEAANRIIHTIRSRRPQMVRSVEALCDAYIILANLDAAQW
RAQRKGISIPADQPITKLKNLEDVVVPTMEIKVDPTGEYRNLVTIQSFKAEFRLAGGLNL
PKIIDCLGSDGKERRQLVKGRDDLRQDAVMQQVFQMCNMLLQRNTETRKRKLTICTYKVV
PLSQRSGVLEWCTGTVPIGEFLVNNENGAHKRYRPKDFSALHCQKKMMDVQKKSFEEKYK
TFMDVCQKFQPVFRYFCMEKFLDPAVWFEKRLAYTRSVATSSIVGYILGLGDRHVQNILI
NEQSAELVHIDLGVAFEQGKILPTPETVPFRLTRDIVDGMGITGVEGVFRRCCEKTMEVM
RSSQETLLTIVEVLLYDPLFDWTMNPLKALYLQQRPEDDTELHSTPGGEDQECRRSLSDT
DQSFNKVAERVLMRLQEKLKGVEEGTVLSVGGQVNLLIQQAMDPKNLSRLFPGWKAWV |
|---|
| NT seq |
9177 nt +upstreamnt +downstreamnt
atgagcttagcacttaatgatctgcttatttgctgccgtcatctagaacatgatagagct
acagaacgaaggaaagaagttgagaaatttaagcgcctgattcgggatcctgaaactgtt
caacatttagatcgacattcagattccaaacaaagcaaatatttgaactgggatgctgtt
tttagatttttacagaaatatgttcagaaagaaacagaatgtctgcgaacagcgaaacca
agcgtatcagcctcaacacaagccactaggcagaaaaagatgcaagaaatcagtagtttg
gtcaagtacttcatcaaatgtgcaaataaaagagcacccagactaaaatgtcaagaactc
ttgaattatatcatggatacagtgaaagattcatctaatggtcccgtttatggagcggat
tgtagcaacattctgctcaaggacattctctcagtgaggaaatattggtgtgaaatatct
cagcaacagtggctagaattgttctctgtgtactttggtctgtaccttaaacctgcacaa
gacattaatagagttttagtggctagaataattcatgctgtgaccaaaggatgctgttca
caaaccgatggattaaatgccaaatttttggatttcttttccaaggctattcagcatgca
agacaggagaagagctctgcaggtctaaatcacatcttagcagcgtttattatcttcctc
aagacgttggctgtaaactttcgaattcgagtgtgtcaattaggagatgaaattcttcct
accttgctttatatttggacccaacatagacttaacgattccttaaaagaagtaattatt
gaattatttcaactgcagatttatgtgcatcatccaaagggagctaaaacccaagaaaaa
ggtgcttatgaatcaagtaaatggaaaagtatcttgtataacttatatgatctgctaatt
aacgagatcagtcatataggaagcagagggaaatattcttcaggatctcgtaatgttgct
gtcaaggaaaacttgattgagttgatggcagatatttgtcaccagatttttaatgaggat
actagatctttggagatttctcagtcttacactaccacccaaagagaacttaatgattac
agcacgccttgcaaaaagaagaaaatagaattaggctgggaggtgataaaagatcatctt
cagaagtcacagagtgattttgatcttgtgccttggttacagatcacaacccagttaata
tccaaatatccttcaagtttacctaactgtgagttgtcaccattactggtgatactatac
cagcttctgcctcaacatcgacatggggagcgcacgccgtatgtgttacgatgccttaca
gaagttgcattgtgtcaagggaagaaatccaacctagaagtctcacagaagtcagattta
ttgaaattctggattaaaatttggtctcttacctttcgtggtataagttctgagcaaata
caagctgaaaactttggtttacttggagctataattcaaggcagtttaattgaggttgat
agagaattctggaagttatttactgggtcagcctgcagaccatcatgtcctgcagtatgc
tgcttgactctggcaatgaccgtctgtgtggttccagaaactgtaaaaacaggagtggag
cacagtctgtgtgaagtaaatagaagttgttctttaaaggaattgataatgaaatggctc
ttactctatcatttagaggatgactttgaagacggtacagagctgcctccagttcttcac
agtaattttcctcatcttgcagtggagaaaattcttgtgagtctcactatgaaaaattgt
aaagctgcaatgaattttctccaaagagtgccagaatgtgaacaacaccaaaaagatcaa
gaagagcctccattctcagaagttgaagaactgtttcttcagacaacttttgacaagatg
ggttttttaaccattgtgaaagaatgtgctgtagaaaagcaccagtccaccgtaggcttt
tctgtccaccagaacctcaaggaatcactggatcgctatcttctgggattatcagagcag
cttttacataactactcatctgagactacaaatgcagaaacgcttatccggtgttcaagt
cttttggtgggtgttcttggctgctattgttatgtgggagtaatagctgaagaggaagca
tatagatcagaactattccagaaagccaagtctctaatgcagtgtgcgggagaaagtatc
actctgttcaaaagtaagaccaatgaggaatctaggattgcttccctgagaaatatgatg
aatctctgtaccagttgcttgtgtaattgtaccaagcccagtccaaataagattgcatct
agatttttcctacgattgttgacatcaaagctcatgaatgatattgcagatatttgtaga
agtttggcgtcctttatcagaaagccatctgactttggagaagtagaatcgctggaagat
gaggctgatgaaaatctgatggaggtggaggatcagtcatccatgaccctgttcagtgac
taccctcctggcagctccagtgatgcccccatgtctggagatggccagagtacttttggt
gccatgaatcctttagctgaagaacatctgtcaaagcaagatctgctctttttagacatg
ctcaagttcttgtgtgtgtgcgtaactacagctcagaccagtccagtgtcatttagagca
gcggacattcggaggaagttgttaatgttaattgatactagcatgctagaccctactaaa
tccctccacctacacatgtatctactgcttttaaaggagcttcctggagaagaatatcct
ttgcccatggaagaggttgttgaacttctaaaaccactctccaatgtgtgttctttgtat
cgccgtgaccaggatgtttgtaaaacacttttaaaccactttgttcatatagtgaggaac
ctgtgtcaaggggatatggatgctgaaaacgcaagggatgctcaagggcagtttctgaca
gtgattggagcattctggcacctagcaaaggaggggaaatgcacattctctgtaagaatg
gcactagtgaagtgccttaaaactttgcttgagaccgatccttattcaaaatgggctatt
cttaatgtaatgggaaaagactttcctgtaaacgaagtatttccacattttcttgctgat
aaccatcatcaagttagcatgttggcagcagagtcaatcaacagattattccaggatatg
aaacacagaggttcgtccacattatggaaagcacttcctttgaagcttcagcaaacagct
tttgaaaatgcatacttgcaagctcaggaaggaatgagagaagtgtcccacagagctaag
aaccctgaacttttggatgagatttataacagaaaatctgttttactgatgacgatagct
gtggttttatgctgtagcccagtctgtgaaaaacaggctttgtttgcgctgtgcaagtct
gtaaaagagaatggattagaacctcaccttgttaaaaaggttttagggaaagtttctgaa
acttttggatacagacgtttagaagactttatggcttctcatttggattatctggttttg
gaatggctaaatcttcaagatactgaacatagcttatattcttttccttttattttacta
aactatacaaccgttgaggatttctatagatcatgttacaaggttttgatcccacatcta
gtgattagaagtcgttttgatgaggtgaagtccattgctaatcagatcgaagaggattgg
aaaagtcttctaacacactgctttccaaagattcttgtaaatattcttccttacttcgcc
tacgagggtacaggagacagtgggatggcacagcagagagagactgctaccaaagtctac
gatatgcttaaagatgaaaatttactaggaaaacagattgatcatttattccttagtaat
ttgccggagatcgttgtggagttattgatgacgttacatgagcccgcagctgcaggcacc
agccaaagcacggacctgtgtgacttttcaggggatttggatcctgcacctaacccacct
cattttccttcacatgtgattaaagcaacgtttgcctacatcagcaattgccataaaacc
aagcttaaaagcattttagaaattctttccaaaagccctgattcctatcagaaaattctt
ctagccatatgtgagcaagctgctgagacaaataatgtttataaaaagcacagaattctt
aaaatatatcacctgtttgttactttattactgaaagatattaaaagtgccttaggagga
gcttgggcctttgttcttcgagatgttatctatactttgattcattatatcaacaaaaag
ccttctcgtttcgtggatgtgtcgtcacggagcttctccctgtgttgtgacctgttaagc
cgggtttgccacacggcagtcacttactgtaaggacgctctggaaaatcatctccacgtg
attgttggcacacttataccccttgtggacgatcagatggaggtgcagggacaggtgttg
gacttgttgaaatacttagtgatagataacaaggataatgaaaacctctatatgacaatt
aaacttttagatccttttcctgaccatgatgtctttaaggatttgcgcattactcagcag
aaaattaaatacagtaaaggacccttttcgcttttggaggaaataaatcattttctctct
gtgagtgcttatgatgcccttcccctgacaaggctggaaggcctgaaggatctccgcaga
cagctagctcagcataaggaccagatggccggcctcatgagagcatctaaggataacccg
caggacggcataatggtgaagctcattgtcagcttgttgcagttatgcaagatggcggtg
aaccacactggtgaaatagaagttttagaggctgttggaagctgcctgggagaagtgggt
cctgtcgatttctccacgatagctctgcagcacagtggagatacgtcttctaccaaggcc
cctgagttgtttaaggataaggaacttcagtggaccttcataaccctgacctacctgaat
aacacgctggtagaagactgtgtcaaagtgcgatcggctgctgctacctgtttgaaaagc
attttagccacaaagactggacatagtttctgggagatttataagacgacacctgatccc
atgctgatctacctacagcctttcagaacatcaaaaaaaaagtttttagaagtccccaga
ctggagaaagaaagtccattagaaggcctggatgatatgagcctgtggattcctcaaaat
gaaaatcatgacatttggataaagaggctgacttgcgcctttttggatagtggaggcacg
aaaagtgaaattcttcgattattaaagccaatgtgtgaagtgaaaactgacttttgtcag
gctgtgcttccatacttgattcacgatattttactccaagatacagaggaatcctggaga
aatctgctttctgcgcacattcagggatttttcactaactgtttcagacactcctcacca
ccgagccgatccacgacccctgccaatttggattcagagtcagagcacctgttccgatgc
tgtgtggacaaaaaatcacagagaacgatgcttgctgttgtggactacatgaggagacaa
aagagaccttccctaggaacagttttcgatgatgctttctggctggagttgaattatcta
gaggttgccaaggtggctcagtcttgtgctgctcactttacggcactgctctacgcagaa
atctacgcagataagaaaagcatggaagaccaagacaaaagaagtcttacgtttgaagaa
gcaagccagagtacagctatttctagtttgagtgaaaaaagtaaagaagaaactggaata
agtttgcaggatctgctcttagaaatctacagaagtataggagagcccgacagtctgtat
ggctgtggtggagggaaactgctacagcccctcactagactgcgcacatatgaacatgaa
gcaatgtggggaaaagccctggtgacatatgaccttgagacggccatatccccatcaacc
cgccaggcagggataatccaggccttgcagaatttgggactctgccatattctttccgtc
tatttaaaaggactagatcatgaaaataaggagcggtgcgctgagctgcaggagctccac
taccaggcagcttggaggaacatgcagtgggaccactgcctttccgtcaacaaaggtgtg
gaaggaaccaattaccacgaatcattgtacaatgctgtgcagtctctgagagatagagaa
ttctccacattttacgaaagtctcagatatgccagggtgaaagaagtggaggagctgtgc
aagggggggctcgagtctgtgtactccctgtaccccacactcagcaggctgcaggccatt
ggtgagctcgagaacatcggggagctgctcgccagatcaggcacggatagtaggcagccc
tctgaagtatacgctaagtggcggaaacactcccagcttctcaaagacagtgatttcagt
tttcaggagcccatcatggctctccgcacagtcattttggagatcctgatggaaaaggaa
atggagaactcccagaaagaatgttttagggacattctcaccaagcaccttgtagaactc
tccatactagcccgaactgtcaagaacactcagctccctgaaagggcaatgtttcaaatt
aaacagtataatccagctagttgtggagtctctgagtggcagctggaggaagcccaagta
ttttgggcaaaaaaggagcagagtcttgccctgagtattctcaagcagatgatcaagaag
ttggatgccagttgtgcagagaatgatcccgacctaagacttatatacgcagaatgtctg
cgagtttgcggcacctggttagcagaaacttgcctagaaaaccctgcggtcatcatgcag
acttatctagaaaaggcagtggaagttgctagaaattatgatggagaaagcagtgatgag
cttaaaaatggaaaaatgaaagcatttctctcattagcacggttctcggacacgcagtac
cagagaattgaaaactacatgaaatcgtcagagtttgaaaacaagcaggctcttctgaaa
agggccaaagaagaagtgggccttcttagggaacataaaatccagaccaacagatacaca
gtaaaggtccagcgggagctggagctggatgaatgtgcactccgtgcactgaaagaggac
cgtaaacgtttcctatgtaaagcagttgaaaattacatcagttgcttactgagtggagaa
ggacacgatatgtggatattccgtctttgttctctctggcttgaaaattccggagtttcc
gaagtcaatggcatgatgaagatcgatggaatgaagattccatcctacaaatttttgccc
cttatgtaccagttggctgctagaatggggaccaaaatgatgggaggcctcggatttcat
gaagtcctcaataatcttatctctagaattgcaatggatcacccccatcacactttgttt
attatactggccttagcaaatgcaaacaaagatgaatttttgaccaaaccagaggcagca
ggaaggaacagaataactaaaaatgcacctaaacaaagctctccgctcgatgaggatcga
accgaggctgcaaatagaataatacatactatcagaagtaggagacctcagatggtcaga
agtgtggaggcgctctgtgatgcttatatcatattagcaaacttagacgctgctcagtgg
agggctcagagaaaaggcataagtatcccagcagaccagccaattactaaactgaagaat
ttagaagatgtcgttgttccaactatggaaattaaggtggaccctaccggagaatacaga
aatctggtgactatacagtcatttaaagcagaatttcgtttagcaggaggtttaaattta
cctaaaataatagactgtctgggctctgatggcaaggaaaggagacagctcgtcaagggc
cgtgacgacctgagacaggacgcggtcatgcagcaggttttccagatgtgtaatatgtta
ctgcagaggaacacggagaccaggaagaggaaactgaccatctgcacatacaaggtggtc
ccgctttctcagcgaagtggagtccttgaatggtgcacaggaactgtccccattggtgag
ttccttgtgaacaacgagaacggtgctcataagagatacaggccgaaggacttcagcgcc
cttcactgccagaagaaaatgatggatgtacaaaagaagtcttttgaagagaaatataaa
acgttcatggatgtctgccagaaatttcaaccggttttccgttacttctgcatggaaaaa
ttcttggacccagctgtttggttcgagaagcgactggcttatactcgcagcgtggctact
tcctctatcgttggttacatacttggacttggtgatcgacatgtacagaatatcttgata
aatgagcagtctgcagaacttgtacatatagatttgggagttgcttttgagcagggtaag
atcctccctactcccgaaacggttcctttcagactcaccagagatattgtggatgggatg
ggcattactggtgttgaaggtgtcttcagaaggtgctgtgaaaaaaccatggaggttatg
agaagctctcaggaaaccctgctaaccattgtggaggttctcctctacgaccccctgttt
gactggaccatgaatcctctgaaagctctgtatttacagcagaggccggaagatgacact
gagctgcactccactcccggcggagaggaccaggaatgcagacgcagtctcagtgacacc
gaccagagcttcaacaaagtagcggaacgcgtgttgatgagactacaagagaaactgaaa
ggagtggaggagggaacggtgctcagtgttggggggcaggtgaatctgctcatacagcaa
gccatggaccccaaaaatctcagccgacttttcccaggatggaaagcttgggtgtga |
|---|
