Ailuropoda melanoleuca (giant panda): 100482656 Help Entry 100482656         CDS       T01329                                  Symbol NF1 Name (RefSeq) neurofibromin   KO K08052   neurofibromin 1 Organism aml  Ailuropoda melanoleuca (giant panda) Pathway aml01521   EGFR tyrosine kinase inhibitor resistance aml04010   MAPK signaling pathway aml04014   Ras signaling pathway Brite KEGG Orthology (KO) [BR:aml00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     100482656 (NF1)    04014 Ras signaling pathway     100482656 (NF1)  09160 Human Diseases   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     100482656 (NF1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PH_NF1 RasGAP CRAL_TRIO_2 CRAL_TRIO MIF4G_like_2 Motif Other DBs NCBI-GeneID:  100482656 NCBI-ProteinID:  XP_034496531 Ensembl:  ENSAMEG00000005313 LinkDB All DBs Position 13:5907400..6118529 Genome browser AA seq 2840 aa AA seqDB search MMPEGDSCHLCRQCRGREGKLPIKTGQQNTHTKVSTEHNKECLINISKYKFSLVISGLTT ILKNVNNMRIFGEAAEKNLYLSQLIILDTLEKCLAGQPKDTMRLDETMLVKQLLPEICHF LHTCREGNQHAAELRNSASGVLFSLSCNNFNAVFSRISTRLQELTVCSEDNVDVHDIELL QYINVDCAKLKRLLKETAFKFKALKKVAQLAVINSLEKAFWNWVENYPDEFTKLYQIPQT DMAECAEKLFDLVDGFAESTKRKAAVWPLQIILLILCPEIIQDISKDVVDENNMNKKLFL DSLRKALAGHGGSRQLTESAAIACVKLCKASTYINWEDNSVIFLLVQSMVVDLKNLLFNP SKPFSRGSQPADVDLMIDCLVSCFRISPHNNQHFKICLAQNSPSTFHYVLVNSLHRIITN SALDWWPKIDAVYCHSVELRNMFGETLHKAVQGCGAHPAIRMAPSLTFKEKVTSLKFKEK PTDLETRSYKYLLLSMVKLIHADPKLLLCNPRKQGPETQGSTAELITGLVQLVPQSHMPE IAQEAMEALLVLHQLDSIDLWNPDAPVETFWEISSQMLFYICKKLTSHQMLSSTEILKWL REILICRNKYLLKNKQADRSSCHFLFLYGVGCDVPSSGTTGQMSMNHEELLPSCTPGASL RKGKGNSSMDSAAGCSGTPPICRQAQTKLEVALYMFLWSPDTEAVLVAMSCFRHLCEEAD IRCGVDEVSVHNFLPNYNTFMEFASVSNMMSTGRAALQKRVMALLRRIEHPTAGNTEAWE DTHAKWEQATKLILNYPKAKMEDGQAAESLHKTIVKRRMSHVSGGGSIDLSDTDSLQEWI NMTGFLCALGGVCLQQRSNSGLATYSPPMGPVSERKGSMISVMSSEGNADTPVSKFMDRL LSLMVCNHEKVGLQIRTNVKDLVGLELSPALYPMLFNKLKNTISKFFDSQGQVLLTDTNT QFVEQTIAIMKNLLDNHTEGSSEHLGQASIETMMLNLVRYVRVLGNMVHAIQIKTKLCQL VEVMMARRDDLSFCQEMKFRNKMVEYLTDWVMGTSNQAADDDVKCLTRDLDQASMEAVVS LLAGLPLQPEEGDGVELMEAKSQLFLKYFTLFMNLLNDCSEVEDENAQTGGRKRGMSRRL ASLRHCTVLAMSNLLNANVDSGLMHSIGLGYHKDLQTRATFMEVLTKILQQGTEFDTLAE TVLADRFERLVELVTMMGDQGELPIAMALANVVPCSQWDELARVLVTLFDSRHLLYQLLW NMFSKEVELADSMQTLFRGNSLASKIMTFCFKVYGATYLQKLLDPLLRIVITSSDWQHVS FEVDPTRLEQSESLEENQRNLLQMTEKFFHAIISSSSEFPPQLRSVCHCLYQATCHSLLN KATVKEKKENKKSVVSQRFPQNSIGAVGSAMFLRFINPAIVSPYEAGILDKKPPPRIERG LKLMSKILQSIANHVLFTKEEHMRPFNDFVKSNFDAARRFFLDIASDCPTSDAVNHSLSF ISDGNVLALHRLLWNNQEKIGQYLSSNRDHKAVGRRPFDKMATLLAYLGPPEHKPVADTH WSSLNLTSSKFEEFMTRHQVHEKEEFKALKTLSIFYQAGTSKAGNPIFYYVARRFKTGQI NGDLLIYHVLLTLKPYYAKPYEIVVDLTHTGPSNRFKTDFLSKWFVVFPGFAYDNVSAVY IYNCNSWVREYTKYHERLLTGLKGSKRLIFIDCPGKLAEHIEHEQQKLPAATLALEEDLK VFHNALKLAHKDTKVSIKVGSTAVQVTSAERTKVLGQSVFLNDIYYASEIEEICLVDENQ FTLTIANQGTPLTFMHQECEAIVQSIIHIRTRWELSQPDSIPQHTKIRPKDVPGTLLNIA LLNLGSSDPSLRSAAYNLLCALTCTFNLKIEGQLLETSGLCIPANNTLFIVSISKTLAAN EPHLTLEFLEECISGFSKSSIELKHLCLEYMTPWLSNLVRFCKHNDDAKRQRVTAILDKL ITMTINEKQMYPSIQAKIWGSLGQITDLLDVVLDSFIKTSATGGLGSIKAEVMADTAVAL ASGNVKLVSSKVIGRMCKIIDKTCLSPTPTLEQHLMWDDIAILARYMLMLSFNNSLDVAA HLPYLFHVVTFLVATGPLSLRASTHGLVINIIHSLCTCSQLHFSEETKQVLRLSLTEFSL PKFYLLFGISKVKSAAVIAFRSSYRDRSFSPGSYERETFALTSLETVTEALLEIMEACMR DIPTCKWLDQWTELAQRFAFQYNPSLQPRALVVFGCISKRVSHGQIKQIIRILSKALESC LKGPDTYNSQVLIEATVIALTKLQPLLNKDSPLHKALFWVAVAVLQLDEVNLYSAGTALL EQNLHTLDSLRIFNDKSPEEVFMAIRNPLEWHCKQMDHFVGLNFNSNFNFALVGHLLKGY RHPSPAIVARTVRILHTLLTLVNKHRNCDKFEVNTQSVAYLAALLTVSEEVRSRCSLKHR KSLLLTDISMENVPMDTYLHHGDPSYRTLKENQPWSSPKGSEGYLAATYPTVGQTSPRAR KSMSLDMGQPSQANTKKLLGTRKSFDHLISDTKAPKRQEMESGITTPPKMRRVAETDYEM ETQRISSSQQHPHLRKVSVSESNVLLDEEVLTDPKIQALLLTVLATLVKYTTDEFDQRIL YEYLAEASVVFPKVFPVVHNLLDSKINTLLSLCQDPNLLNPIHGIVQSVVYHEESPPQYQ TSYLQSFGFNGLWRFAGPFSKQTQIPDYAELIVKFLDALIDTYLPGIDEETSEESLLTPT SPYPPAVQSQLSITANLNLSNSMTSLATSQHSPGIDKEHVELSPTTGHCNSGRTRHGSAS QVQKQRSAGSFKRNSIKKIV NT seq 8523 nt NT seq  +upstreamnt  +downstreamnt atgatgccagaaggagacagttgccacctctgcaggcagtgtagaggaagagaggggaag cttccaataaaaacaggacagcagaacacgcataccaaagtcagtaccgaacacaacaag gaatgtcttattaatatttccaaatacaagttttctttggttatcagcggcctcaccact atcttaaagaatgttaacaatatgagaatatttggagaggctgctgaaaaaaatttatat ctctctcagttgattatattggatacactggaaaaatgtcttgctgggcaaccaaaggac acaatgagattagatgaaacaatgctggtcaaacagttgctgccagaaatctgccatttt cttcatacctgtcgtgaaggaaaccaacatgccgctgaacttcggaattccgcctctggg gttttattttctctcagttgcaacaacttcaatgcagtgtttagtcgcatttctaccaga ttacaggaattgactgtttgttcagaagacaatgttgatgttcatgatatagaattgtta cagtatatcaatgtggattgtgcaaaattaaaacgactcctaaaggaaactgcatttaaa tttaaagcgctaaagaaggttgcacagttagcggttataaatagcctggaaaaagcattt tggaactgggtagaaaattatccagatgaatttacaaagctataccagattccacagact gatatggctgagtgtgcagaaaaactgtttgacttggtggatggttttgctgaaagcacc aaacgtaaagcagcagtttggccattacaaatcattctccttatcttgtgtccagaaata atccaggatatatccaaggatgtggttgatgaaaacaacatgaataagaagttgttcctg gacagtctacgaaaagcacttgctggccacggaggaagcaggcagctgacggaaagtgct gcaatcgcttgtgtcaaactgtgtaaagcaagtacttacatcaattgggaagataactct gtcattttcctactagttcagtccatggtggttgatcttaagaacctgctttttaatcca agtaaaccattctcaagaggcagtcagcctgcagatgtggatctcatgattgactgcctt gtttcttgctttcgtataagccctcacaacaaccaacattttaagatctgcctggctcag aattccccttctacatttcactatgtgctggtaaattcactccatcgaatcatcaccaat tctgcgttggattggtggcccaagattgatgctgtatattgtcactcagttgagcttcga aacatgtttggcgaaacccttcataaagctgtgcagggttgtggagcacacccagcaata cgaatggcaccgagtcttacatttaaagaaaaagtaacaagccttaaatttaaagaaaaa cctacagacctggagacaagaagctataagtatcttctcttgtccatggtgaaactaatt catgcagatccaaagctcttgctttgtaatccaagaaaacaagggcctgaaacccaaggc agtacagcggaattaataacagggctcgtccagttggtccctcagtcacacatgccagaa attgctcaggaagcaatggaggctctgctggttctgcatcagttagacagcattgatttg tggaatcctgatgctcctgtagaaacattttgggaaatcagctctcaaatgcttttttac atctgcaagaaattaactagccatcaaatgcttagtagcacagaaattctcaaatggttg cgggaaattttgatctgcaggaataaatatcttcttaaaaataagcaggcagatagaagt tcctgtcactttctcttcctttatggggtaggatgtgatgttccttcgagtggaactact ggtcagatgtccatgaatcatgaagaactactaccttcttgtactcctggagcctctctt cggaaggggaaaggaaactcatcgatggatagtgcagcagggtgcagcggcaccccgccg atctgccgacaagctcagactaaactagaagtggccctgtacatgtttctgtggagccct gacactgaagctgtcctggtggccatgtcctgtttccgccacctctgcgaggaagcagat atccggtgtggcgtggatgaggtgtcggtgcacaacttcttgcccaactataacacgttt atggaatttgcctctgtcagcaatatgatgtcaacaggaagagcagcacttcagaaaaga gtgatggcactactaaggcgcattgagcatcccactgcaggaaacactgaggcttgggaa gatacgcatgcaaagtgggaacaagctacaaaactaatcctcaactacccaaaagctaaa atggaagatggccaggctgctgaaagccttcacaagaccattgttaagaggcgaatgtct catgtgagtggaggaggatccatagatttgtctgacacggactccctacaggaatggatc aacatgactggcttcctttgtgcccttgggggagtgtgcctgcagcagagaagcaattct ggcctggcaacctatagcccacccatgggcccagtcagtgaacgtaagggttccatgatt tcagtgatgtcttcggagggaaatgcagatacacctgtcagcaaatttatggatcggctg ttatccttaatggtgtgtaaccatgagaaagtgggacttcaaatacggaccaatgttaag gatctggtgggtcttgaattgagtcctgctctttatccaatgctgtttaacaaattgaag aataccatcagcaagttttttgactcccaaggacaggttttattgactgacaccaatacg caatttgtggagcaaaccatagctataatgaagaatttactagataatcatactgaaggc agctcagaacatctggggcaagctagcattgaaacaatgatgttaaatctagtcagatac gttcgtgtgcttgggaatatggtccatgcaattcaaataaaaacgaaactgtgtcagtta gtcgaggtaatgatggcaaggagagatgacctctcattttgtcaagagatgaaatttagg aataagatggtagaatacctgacagactgggtaatgggaacatcaaaccaagcagcagat gatgacgtaaagtgtcttacaagagacttggaccaggcgagcatggaagcagtagtttca ctcctggctggtcttccgctgcagccggaggaaggagatggtgtggaattgatggaagcc aaatcacagttatttcttaagtatttcacattgttcatgaacctcttgaatgactgtagt gaagttgaagatgaaaatgcacaaacaggtggcaggaaacgtggcatgtctcggaggctg gcatcactgaggcactgtacagtccttgcaatgtcaaacttactcaatgctaatgtggac agtggcctcatgcactccataggtttaggttatcacaaagatcttcagacaagagctaca tttatggaagttctgacaaaaattctccagcaaggcacagaatttgacacacttgcagaa acagtgctggccgaccggtttgagaggctggtggagttggtcacaatgatgggagaccag ggagagctcccgatagccatggcgctggccaatgtggtcccatgttctcagtgggatgaa ctagctcgagttctagtgactctgtttgattctcggcatttactctaccaactgctctgg aacatgttttctaaggaagtagaattggcagactccatgcagactcttttccgaggaaac agcttagccagtaaaataatgaccttctgtttcaaggtatatggtgctacctacctacaa aaactcctggatccgttattacgaattgtgatcacatcctctgattggcagcatgttagc tttgaagtggatcctaccaggttagagcagtcagagagccttgaggaaaaccaacggaac cttcttcagatgactgaaaagttcttccatgccatcatcagttcctcctcagaattcccc cctcagcttcgaagtgtgtgccactgtttataccaggcaacttgccactccctactgaat aaagctacagtaaaagaaaaaaaggaaaacaaaaaatcagtggttagccagcgtttccct cagaacagcatcggtgcagtgggaagtgccatgttcctcagatttatcaatcctgccatc gtctcaccatatgaagcagggattttagataaaaagccaccacctagaatcgaaaggggc ttgaagttaatgtcaaagatacttcagagtattgccaatcatgttctcttcacaaaagaa gagcatatgcggccttttaatgattttgtgaaaagcaactttgatgcagcacggaggttt ttccttgatatagcatctgactgtcctacaagtgatgcagtaaatcatagtctttccttc atcagtgatggcaatgtgcttgctttacatcgtctgctctggaacaatcaagagaaaatt ggccagtatctttctagcaacagggatcacaaagctgttggaagacgacctttcgataag atggcaacacttcttgcatacctgggtcctccagagcacaaacctgtggcagatacacac tggtccagccttaaccttaccagttcaaagtttgaggaatttatgactaggcatcaagta catgaaaaagaagagttcaaggctttgaaaacattaagtattttctaccaagctgggact tccaaagctgggaaccctatattttattatgttgcacggaggtttaaaactggtcaaatc aatggcgatttgctgatctaccatgtcttgctgactttaaagccatattatgcaaagcca tatgaaattgtagtggaccttacccatactgggcctagcaatcgctttaaaacggacttt ctctccaagtggtttgttgtttttcctggctttgcttatgacaatgtctctgcagtctat atctataactgtaactcctgggtcagggagtacaccaagtatcacgagcggctgctgact ggcctcaaaggcagcaaaaggctcatcttcatagactgtcctgggaaactggctgagcac atagagcatgaacagcagaaactgcctgctgccacgttggctttagaagaggacctgaag gtatttcacaatgctctcaagctagctcacaaagacaccaaggtttctattaaagttggt tctactgctgtccaagtaacctcagcagagcgaacaaaagtcctggggcaatcagtcttt ctaaatgatatctattatgcttcggaaattgaagagatctgcctggtggatgagaaccag tttaccttaaccattgcaaaccagggcacaccgctcaccttcatgcaccaggagtgtgaa gccattgtccagtctatcattcatatccggacacgctgggagctgtcgcagcctgactcc atcccccagcacaccaagattcggccaaaagatgtccctgggacgctgctcaatattgca ttacttaatttaggcagttcagaccctagtttacggtcagctgcctataatcttctgtgt gccttaacttgtacctttaatttaaaaatcgagggccagttactagagacatcaggttta tgcatccctgccaacaacaccctctttattgtctctattagtaagacactggcagccaat gagccacatctcaccttagaatttttggaagagtgtatttctggatttagcaaatctagt attgaattgaaacacctttgtttggaatacatgactccatggctgtcaaatctcgtccgt ttttgtaagcacaatgatgacgccaaacgtcagagagttactgctattcttgataagctg ataaccatgaccataaatgagaagcagatgtacccatctatccaagccaaaatatggggg agccttgggcagattacagatctccttgacgttgtactagacagtttcatcaaaaccagt gcaacaggtggcctgggatcaataaaagctgaggtgatggctgatactgctgtagctttg gcttctggaaatgtgaaattggtttcaagcaaggttattggaaggatgtgcaaaataatt gacaagacatgcttatctccaactcctaccttagaacaacatcttatgtgggacgatatt gctattctagcacgctacatgctgatgctgtccttcaacaattcccttgacgtggcagct catctcccctacctcttccacgttgttactttcttagtagccacagggcctctctccctt agagcttccacacacggattggtcattaatatcattcactctctgtgtacttgttcacag cttcattttagtgaagagaccaagcaagttttgagactcagtttgacagagttctcatta cccaagttttacctgctgtttggcattagcaaagtcaagtcagctgccgtcattgccttc cgctccagttaccgggacaggtcattctctcccggctcctatgaaagggagacttttgct ttgacgtccctggaaacagtcacagaagctttgttggagatcatggaggcatgtatgaga gatattccaacatgcaagtggctggaccagtggacagaactggctcaaagatttgcattc caatataatccatccttgcaaccaagagctcttgttgtcttcggctgtattagcaaacga gtgtctcatgggcagataaagcagattatccgtattcttagcaaggcacttgagagttgc ttaaaaggacctgatacttacaacagtcaagttctgatagaagctacagtaatagcacta accaagttacaaccacttcttaataaggactcccctcttcacaaagccctcttctgggtc gctgtggctgtgcttcagctcgacgaggtcaacctgtactcagcaggcaccgcacttctg gaacagaacctgcacaccttagacagcctgcggatattcaacgacaagagtccagaggaa gtatttatggcaatccggaatcctctggaatggcactgcaagcaaatggatcattttgtt ggactcaatttcaactctaactttaactttgcactggttggacatctcttaaaagggtac agacatccttcacctgccattgttgcaagaacagtgagaattttgcatacactactaact ctggttaacaaacatagaaactgtgacaaatttgaggtgaacacacagagcgtggcttac ttagcagccttactcacagtgtctgaggaggtccgaagtcgctgtagcctaaaacataga aagtctcttcttcttactgatatttcaatggaaaatgttcctatggatacatatctccat catggcgaccctagctataggacactaaaggagaaccagccgtggtcatctcccaaaggt tctgaagggtaccttgcagccacctatccaaccgtgggccagaccagtccccgagccagg aaatccatgagtttggacatggggcagccttctcaggccaatacgaagaagttgctggga acaaggaaaagttttgatcacttgatatcagacacaaaggctcctaaaaggcaagaaatg gaatcagggatcacaacaccccccaaaatgaggagagtagcagaaactgattatgaaatg gaaactcagaggatttcctcatcacaacaacacccacatttacgcaaagtttcagtgtcc gaatcaaatgttctcttggatgaagaagtacttactgatccgaagatccaagcacttctt cttactgttctggcgacgctggtaaaatacaccacagatgagtttgatcagcgaattctt tatgaatacttagcggaagccagtgttgttttccccaaggtctttcctgtcgtgcacaat ttattggactcaaagatcaacaccctgttgtcattgtgccaagatccaaatttgttaaat ccaattcatggaatcgtgcagagcgtggtgtaccatgaagaatccccaccacagtaccaa acatcttacctacaaagttttggttttaatggcttgtggcggtttgcaggacccttttca aagcaaacacaaatcccagactatgctgagcttattgttaagtttcttgatgccttgatt gacacgtatttgcctggaattgatgaagaaaccagtgaggagtccctcctgacacccact tctccttatcctcctgcagtgcagagccagcttagtattactgctaaccttaacctttct aattccatgacctcacttgcaacttcccagcattccccaggaatcgacaaggagcacgtt gaactctcccccaccactgggcactgtaacagtggacgaactcgccacggatccgcaagc caagtgcagaagcaaagaagcgctggcagtttcaaacgtaatagcattaagaagatcgtg tga

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