| Entry |
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| Symbol |
TBK1
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| Name |
(RefSeq) serine/threonine-protein kinase TBK1 isoform X1
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| KO |
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| Organism |
aml Ailuropoda melanoleuca (giant panda)
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| Pathway |
| aml04620 | Toll-like receptor signaling pathway |
| aml04621 | NOD-like receptor signaling pathway |
| aml04622 | RIG-I-like receptor signaling pathway |
| aml05022 | Pathways of neurodegeneration - multiple diseases |
| aml05163 | Human cytomegalovirus infection |
| aml05167 | Kaposi sarcoma-associated herpesvirus infection |
| aml05168 | Herpes simplex virus 1 infection |
| aml05170 | Human immunodeficiency virus 1 infection |
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| Brite |
KEGG Orthology (KO) [BR:aml00001]
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
100484104 (TBK1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
100484104 (TBK1)
04137 Mitophagy - animal
100484104 (TBK1)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
100484104 (TBK1)
04621 NOD-like receptor signaling pathway
100484104 (TBK1)
04622 RIG-I-like receptor signaling pathway
100484104 (TBK1)
04623 Cytosolic DNA-sensing pathway
100484104 (TBK1)
04657 IL-17 signaling pathway
100484104 (TBK1)
09160 Human Diseases
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
100484104 (TBK1)
05161 Hepatitis B
100484104 (TBK1)
05160 Hepatitis C
100484104 (TBK1)
05171 Coronavirus disease - COVID-19
100484104 (TBK1)
05164 Influenza A
100484104 (TBK1)
05162 Measles
100484104 (TBK1)
05168 Herpes simplex virus 1 infection
100484104 (TBK1)
05163 Human cytomegalovirus infection
100484104 (TBK1)
05167 Kaposi sarcoma-associated herpesvirus infection
100484104 (TBK1)
05169 Epstein-Barr virus infection
100484104 (TBK1)
05165 Human papillomavirus infection
100484104 (TBK1)
09171 Infectious disease: bacterial
05135 Yersinia infection
100484104 (TBK1)
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
100484104 (TBK1)
05022 Pathways of neurodegeneration - multiple diseases
100484104 (TBK1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
100484104 (TBK1)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
100484104 (TBK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:aml01001]
100484104 (TBK1)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:aml04131]
100484104 (TBK1)
Enzymes [BR:aml01000]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.10 IkappaB kinase
100484104 (TBK1)
Protein kinases [BR:aml01001]
Serine/threonine kinases: Other
IKK family [OT]
100484104 (TBK1)
Membrane trafficking [BR:aml04131]
Autophagy
Xenophagy
Other xenophagy associated proteins
100484104 (TBK1)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
15:40042337..40083170
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| AA seq |
729 aa
MQSTSNHLWLLSDILGQGATANVFRGRHKKTGDLFAIKVFNNISFLRPVDVQMREFEVLK
KLNHKNIVKLFAIEEETTTRHKVLIMEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVV
GGMNHLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARELEDDEQFVSLYGTEEYL
HPDMYERAVLRKDHQKKYGATVDLWSIGVTFYHAATGSLPFRPFEGPRRNKEVMYKIITG
KPSGAISGVQKAENGPIDWSGDMPISCSLSRGLQVLLTPVLANILEADQEKCWGFDQFFA
ETSDILHRMTIHVFSLQQMTAHKIYIHSYNTATVFHELVYKQTKIISSNQELIYEGRRLV
IEPGRLAQHFPKTTEENPIFVVSREPLSTIGLIYEKISLPKVHPRYDLDGDASMAKAITG
VVCYACKIASTLLLYQELMRKGIRWLIELVKDDYNETVHKKTEVVITLDFCIRNIEKTVK
VYEKLMKINLEAAELGEISDIHTKLLRLSSSQGTIETSLQDIESKLSPGGLLADTWAHQE
GTHPKDRHVEKLQVLLNCITEIYYQFKKDKAERRLAYNEEQIHKFDKQKLYYHATKAMTH
FTDECVKKYEAFLDKSEEWMRKMLHLRKQLLSLTNQCFDIEEEVSKYQDYTNELQETLPQ
KMFAASSGIKHTMTPIYPCSNTLVEMTLGMKKLKEEMEGVVKELAENNHILERFGSLTMD
GGLHNVDCL |
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| NT seq |
2190 nt +upstreamnt +downstreamnt
atgcagagcacgtctaatcatctgtggcttttatcggatattttaggccaaggagctact
gcaaatgtctttcgtggaaggcacaagaaaaccggtgacttatttgctatcaaagtattt
aataatataagcttccttcgtccagtggatgttcaaatgagagaatttgaagtgttaaag
aaactcaatcacaaaaatattgtcaaattatttgctattgaagaggagacaacaacaaga
cataaagtacttattatggaattttgtccatgtggaagtttatacactgttttagaagag
ccatctaatgcctatggactaccagagtctgaatttttaattgttttgcgagatgtggtt
ggtggaatgaatcatctccgagagaacggcattgtgcaccgtgatatcaagccaggaaat
atcatgcgtgttataggggaggatggacagtctgtgtacaaactcacagattttggcgca
gctagagaattagaagatgatgagcagtttgtttctctgtatggcacagaagaatatttg
catcctgatatgtatgagagagcagtactaagaaaagatcatcagaagaaatatggagca
acagttgatctttggagcattggggtaacattttaccatgcagccactggatcactgcca
tttagaccatttgaagggccacgtaggaataaggaagtgatgtataaaataattactgga
aagccttctggtgcaatatctggagtacagaaagcagaaaatggaccaatcgactggagt
ggagacatgcctatttcttgcagtctttctcggggtcttcaagttctacttacccctgtt
cttgcaaacatcctggaggcagatcaggaaaagtgttggggttttgaccagttttttgca
gaaactagcgatatacttcatcgaatgacaattcatgttttttcgctgcaacaaatgaca
gctcataagatttatattcatagctataatactgctactgtatttcatgaactggtgtat
aaacaaaccaaaattatttcttcaaatcaagaacttatatatgagggacgacgtttagtc
atagaacctggaagactggcacagcatttccctaaaactacggaggaaaatcccatcttt
gtagtaagccgggaacctctgagtaccataggattgatatatgaaaaaatttccctccct
aaagtacatccacgttacgatttagatggggacgcgagcatggctaaggcaataacagga
gttgtgtgttatgcctgtaaaattgccagtaccttgctgctttatcaggaattaatgcga
aaggggatacgatggttgatagaattagtaaaagatgattataatgaaactgttcacaaa
aagacagaagttgtgatcacattggatttctgcatcagaaacattgaaaaaactgtgaaa
gtatatgaaaagttgatgaagatcaacctagaagcagcagagttaggtgaaatttcagac
atacacaccaaattgttgagactttccagttctcagggaacaatagaaaccagtcttcag
gatatcgaaagcaaattatctccaggtggattgctggcagatacatgggcccatcaagaa
ggcactcatccaaaagatagacatgtagaaaagctacaagtcctgctaaattgcatcaca
gagatttactatcagttcaaaaaagacaaagcagaacgtagattagcttataatgaagaa
cagatccacaaatttgataagcaaaaactgtattaccatgcaacaaaagctatgacccac
tttacagatgaatgtgttaagaaatatgaggcatttttggataagtcagaagaatggatg
agaaagatgcttcatcttaggaaacagttactatccctaactaatcagtgttttgatatt
gaagaagaagtatcaaagtatcaagactatacaaatgagttacaagaaactttgccccag
aaaatgtttgcagcctccagtggaatcaagcataccatgaccccaatttatccatgttct
aatacattagtggaaatgactcttggtatgaagaaattaaaggaagaaatggaaggggtg
gttaaagaacttgctgaaaataatcatatcttagaaaggtttggctctttaaccatggat
ggcggccttcacaatgttgactgtctttag |
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