Ailuropoda melanoleuca (giant panda): 100484116
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Entry
100484116 CDS
T01329
Symbol
BCKDHA
Name
(RefSeq) 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial isoform X4
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
aml
Ailuropoda melanoleuca (giant panda)
Pathway
aml00280
Valine, leucine and isoleucine degradation
aml00640
Propanoate metabolism
aml00785
Lipoic acid metabolism
aml01100
Metabolic pathways
aml01210
2-Oxocarboxylic acid metabolism
Module
aml_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
aml00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
100484116 (BCKDHA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
100484116 (BCKDHA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
100484116 (BCKDHA)
Enzymes [BR:
aml01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
100484116 (BCKDHA)
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
100484116
NCBI-ProteinID:
XP_002923727
Ensembl:
ENSAMEG00000011602
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All DBs
Position
12:complement(35592300..35617802)
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AA seq
446 aa
AA seq
DB search
MAVAAAAARVWGSSRGLGRTGLLLLRRPGARGLARSLPRRQEQQHFPSLDDKPQFPGASA
EFIDKLEFIQPNVISGIPVYRVMDRQGQIINPSEDPHLPQEKVLKFYRSMTLLNTMDRIL
YESQRQGRISFYMTNYGEEGTHVGSAAALDNTDLVFGQYREAGVLMYRDYPLELFMAQCY
GNVSDLGKGRQMPVHYGCRERHFVTISSPLATQIPQAVGAAYAAKRANANRVVICYFGEG
AASEGDAHAGFNFAATLECPIIFFCRNNGYAISTPTSEQYRGDGIAARGPGYGIMSIRVD
GNDVFAVYNATKEARRRAVAENQPFLIEAMTYRIGHHSTSDDSSAYRSVDEVNYWDKQDH
PISRLRHYLQSRGWWDDEQEKAWRKQSRKKVMEAFEQAERKPKPNPSLLFSDVYQEMPAQ
LRKQQEALARHLQTYGEHYPLDHFEK
NT seq
1341 nt
NT seq
+upstream
nt +downstream
nt
atggcggtggcggctgcagcagcgagggtttggggctcgagtcgaggcttgggccggact
ggcctcctgctcctgcggcggcctggggctcgggggctggctagatctcttccccggaga
caggagcagcagcacttcccatccctggatgacaagccccagttcccgggggcctcggcg
gagtttatagacaagctagaattcatccagcccaatgtcatctctgggattcccgtctac
cgcgtcatggaccggcagggccagatcatcaaccccagcgaggatccccatctgccccag
gagaaggtgctcaagttctacaggagcatgaccctgctcaacaccatggaccgcatcctc
tacgagtcccagcggcagggtcggatctccttctacatgaccaactatggcgaggagggg
acgcacgtggggagtgcagcagcgctggacaacacggacctggtgttcggccagtaccgg
gaggcaggtgtgctcatgtaccgggactaccccctggagctgttcatggcccagtgctac
ggcaacgtcagtgacctgggcaagggccgccagatgcccgtgcactacggctgcagggag
cgccactttgtcaccatctcctctccgctggccacacagatcccgcaggcggtgggggcg
gcctacgcggccaagcgggccaacgccaacagggtggtcatctgctacttcggggagggg
gcggccagcgagggggatgcgcacgccggcttcaacttcgctgccaccctcgagtgcccc
atcatcttcttctgccgcaacaacggctatgccatctccacgcccacgtcggagcagtac
cgcggggacggcatagctgcccgaggcccgggctatggcatcatgtccatccgtgtggat
ggcaacgacgtgtttgccgtgtacaacgccaccaaggaggcccggcggcgggcggtggcg
gagaaccagcccttcctcatcgaggccatgacctacaggatcgggcaccacagcactagt
gatgacagctcagcctaccgctcggtggacgaggtcaattactgggacaagcaggaccac
cccatctcccggctgcgccattacctgcagagccggggctggtgggacgacgagcaggag
aaggcctggaggaagcaatcccgcaagaaggtgatggaggcctttgagcaggcggagcgg
aagccgaagcccaaccccagcctgctcttctctgacgtgtaccaggagatgcccgcccag
ctccgcaagcagcaggaggccctggcccggcacctccagacctacggggagcactacccc
ctggaccactttgagaagtga
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