Amycolatopsis mongoliensis: QRX60_48250
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Entry
QRX60_48250 CDS
T09938
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
amog
Amycolatopsis mongoliensis
Pathway
amog00300
Lysine biosynthesis
amog00550
Peptidoglycan biosynthesis
amog01100
Metabolic pathways
amog01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
amog00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
QRX60_48250 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
QRX60_48250 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
QRX60_48250 (murF)
Enzymes [BR:
amog01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
QRX60_48250 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
WIY01727
UniProt:
A0A9Y2NEE8
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Position
complement(10072603..10074111)
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AA seq
502 aa
AA seq
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MIVLSLAEIADVVGGRLHRADPGAQVTGSVEFDTRKLTPGGLFVALPGEKVDGHDFAAQA
VEAGAVAVLAAREVDAPAIVVPPPAPGEAHERSVALTGDKDGSGAAVLAALAKLARFVVQ
RLAEGNLTVVGVTGSSGKTSTKDVIAQLLEPLGPTVAPPGSFNNELGHPWTALRADAQTR
HLVLELSARGPGHIAHLAEIAPPKIGVVLNVGTAHVGEFGSREGIAKTKGELVEALPEDG
VAVLNLDDPLVAAMASRTKARVVYVGETPSAQIRAENITLDDEARASFRLITPAGEADVK
LPLHGEHHVGNALSAAAVALELGATPDEIATRLSGLERRSARRMEVVTRPDGVTILNDSF
NANPESMRAGLKALAAMTRESGRRSWAVLGVMGELGADAVTAHDEIGRLVVRLNIAKLVV
IGPEAAAMHQGAFQEGSWGEESTLVPDVEAAIAVLHDQLRPGDVVLVKASKAAGLWRVAE
ALLEPRETSPESSTERSNGGDA
NT seq
1509 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgtgctcagcctggccgagatcgccgacgtcgtcggcggccggctgcaccgcgcc
gacccgggcgcccaggtgaccggcagcgtggagttcgacacccggaagctcacgcccggc
ggcctgttcgtcgccctgccgggggagaaggtcgacggccacgacttcgccgcgcaggcc
gtcgaagccggcgccgtggccgtgctggccgcccgcgaggtcgacgcgcccgccatcgtc
gtcccgccaccggcgccgggcgaggcccacgagcggtcggtcgcgctgaccggcgacaag
gacggctccggcgccgcggtgctggccgcgctcgccaagctcgcccggttcgtagtgcag
cgcctggccgaagggaacctgaccgtcgtcggcgtcaccggctcctccggcaagacgtcg
accaaggacgtcatcgcccagctgctggagccgctcggcccgacggtcgcgccgcccggg
tcgttcaacaacgagctgggccacccctggacggcgctgcgggccgacgcgcagacccgg
cacctggtgctggagctgtccgcgcgcgggccggggcacatcgcccacctcgccgagatc
gccccgccgaagatcggcgtggtgctcaacgtcgggaccgcgcacgtcggcgagttcggc
tcgcgcgagggcatcgcgaagaccaagggcgagctggtcgaggcgctgcccgaggacggc
gtcgcggtgctcaacctggacgacccgctggtcgccgccatggcgagccggacgaaggcc
cgggtggtctacgtcggcgaaaccccgtcggcgcagatccgcgcggagaacatcaccctc
gacgacgaggcccgcgcctccttccggctgatcaccccggccggcgaggccgacgtgaag
ctgccgctgcacggcgagcaccacgtcggcaacgcgctgtccgccgcggcggtcgcgctg
gagctgggcgcgacgccggacgagatcgccacgcgcctgtccgggctcgagcggcgttcg
gcgcggcgcatggaggtcgtcacgcggcccgacggcgtcacgatcctcaacgactccttc
aacgccaaccccgagtcgatgcgggccggcctgaaggccctcgcggcgatgacgcgggag
agcggccgccggtcctgggcggtgctcggcgtgatgggcgagctcggcgcggacgcggtc
accgcccacgacgagatcggccgcctggtcgtccggctcaacatcgccaagctcgtcgtg
atcggtcccgaggcggcggccatgcaccagggcgcgttccaggagggctcctggggcgag
gaatcgactctggtacccgacgtcgaggccgcgatcgccgtgctgcatgatcagctccgt
cccggggacgtggtgctggtcaaggcctccaaggccgccggcctctggcgggttgccgaa
gctctgctcgaaccccgggaaacctccccagaaagctccacggaacgctcgaacggtggt
gacgcgtga
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