Anopheles moucheti: 128298432 Help Entry 128298432         CDS       T09615                                  Name (RefSeq) protein purity of essence   KO K10691   E3 ubiquitin-protein ligase UBR4 [EC:2.3.2.27] Organism amou  Anopheles moucheti Brite KEGG Orthology (KO) [BR:amou00001]  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04121 Ubiquitin system [BR:amou04121]     128298432 Enzymes [BR:amou01000]  2. Transferases   2.3  Acyltransferases    2.3.2  Aminoacyltransferases     2.3.2.27  RING-type E3 ubiquitin transferase      128298432 Ubiquitin system [BR:amou04121]  Ubiquitin ligases (E3)   Single Ring-finger type E3    UBR box proteins     128298432 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  E3_UbLigase_R4 E3_UBR4_N UBR4 zf-UBR Motif Other DBs NCBI-GeneID:  128298432 NCBI-ProteinID:  XP_052890140 LinkDB All DBs Position 2:1237864..1255672 Genome browser AA seq 5510 aa AA seqDB search MAAAHSGGVEWAAILKPFLSSSSENISKTDVLNLIKTIIQNENEILEHDAAYKQFFDNFV VLAAENITSQVTSLSQTQLQQFTEAASILIRYIILHLDTTAPCKPSILLMALKILCEGKR TNENQPNATSSASSIISVSGMKYLKYPEIPGNKPASVGAPSSSGSGSSAAGTSDKESPKT EMKRSRSDLSTVILQQLTTPLCSWAVTFAALSEEQIDCTDLFVKQNLQCMNAINAGESLL KWCSTALGTLAKYRFKYEEYTMLGRPLYLPVTNTEANAIKNIFNLMESDITNLQLAISLP LLEPLTPKKITLLSQCAMSALYCCVLTSTAVSVITMASAGSQKTASSGQLQQAQGQAGGT QTQKETEEEEDFARTIVDKGLEIFTKIGNMLKTSTRTHIYQNHMCMGAWLLISGIQGTMG ASGNTSGLQQMVPISAKTSEESLKGRSPLKTLDVPQMASAQPSPALRVNLFKVQQGFGVL NAAIARHSITLMTELIDDLKIDSRTDDDEYSSIESAGFDILGQYTSIQRVVRVLNSATLQ QLLTFLATVSYRKACTLRRINTKNTNDGEPMSYSDSTTYFNDTFSCSEESEPEEEDSDSY LGLWFKETLSPDMNEEMTESQEQENKDDKGRHGSNLVPAKDEPHEYLNLASLIFNFFDVS LGGNHIYLSRYVKTGLSEQQMVLLANILRDLDRDSARGETDIPGCMQWQNAMVKFSGAVG RYLHNLISNSLLNESLQSALLLHLGVSPWTQDANIWPLQVYSRTLAVLVQILLLKPSQEK EAACLSVWHRLVNTIVEGICSTQTIPNESEIEDLNVEHAQLLLFLFHSLNLMQKKSILLL TAGGVIRCSEVCRSVTPDKPLRDHQIMLLSRLLLFLEYLMKHLYNPPNVLLEQVRWNLFS VFTLDSEQKLADLVNYKTKMMSFCRKDIEDKHRKLANEFSVGGVKPKFYSLTTVESKVQQ EFKLDGLAWNFILCTPDKLKYPWLIDALIDILGITDMCLARIPFQTLCAVHYCFSLSWKL LLGLPPSTQHVEALMQEKSPNLHSLLWSIRCLHPITHSHYLIVNSLVKQGMYTQSAEAMW IRLTEYVSDVKYSLKMTLLGLESFAKSFTPDQPRLSKIILLDSLMSHLFAVCWAEKEGVN VKAVKTSSNTVASSTASSATTTNASTANTGSSTAVTNESNTSGASSTTIPGPANIVVSGA STSTSLTDGSPSVISAEVSRADLTKNIMHALLDVLEIVRESTYKTMFQNLSGQIPSCLIE PLIAIAGTKNSFCSELAQQLVSCITGHDKDVIAVEWRKNLSTLTEENFISGSFPVELHTL TVIEAHLTEVSKHLSYSILLSLKNALKSAVNLIYYMLPNYDDIKLDERLKEILIPMVFDL RAEYLHGPINKCLETLLGGDSNCEAYQLAAFSNIIKHSYQFLIEYTDLCATGCATNIDES VLCNILKYWESMLEKSNGLRAMRNFFYESKSGNLVQILLSFTGTNISQAYSTRVLQFFEK LFQAAEKLDAPFDEEELCSCIAELAVTDSARLKSWLSHILLGPGGISVTPNASNNSSNVP TPTNMATVSAIPSITDQLVGSATAAGGVEAGLSESNTTAANAPTTTEGEQQDAMDIDYEC MTKGSGWQAAATSCGKVAIEDASGETLERNGKLLQSLVKYIVAENRISSSVSEALFQALI QIGHNLLSPTQEAIEFSDLLQVMITLADAGKGRGHGILFTAAIDWLDVCRSQVLDAGKTG SSGWRAAIQLDNVTAILKYMSDLLLGLGAKGSRVLNPPWDEESLLDADDILEELGAEEED STVDDSDEDSLGNKLCTFSITQKDFMNQHWYYCHTCKMVDGVGVCSVCARVCHKNHDISY AKYGNFFCDCGAKEDGSCQALSRRSNSGHAEDSILGSSSAASILPRSNDAESVLLASNLM RRRHPTSPSHEGPSTSRTAQGQASEKEQQLAKIIETSREALNNPSQWKSVIRCILVFFNS LMPTVKEHCARYSPVGCYWRAKSALERLHRPEKSYVLSDDIMIATLGSQEGAFENVRMNY SGEQGQTIKQLLSTYLVRRVALCCLASPHGKRQQLAISHEKGKVTILQLSALLKQADAAK RKLTLTRLASAPVPCTVLSLASNPANEDFLAVCGLKECHILTFTSTGTANDHIVLTPQLD TGNFIKRAIWLPSSQTKLALVTADFVKIYDLADDSYSPQYYFLVPSGKIRDCTFVYDQEG TYYMLIMSSLGYIYTQPLSDESLAKHGPFYVTSTLELDHPLITDDNGQILAGGVSIYYSH VLQLLFFSYAAGRNFMAPLTNVNDGVKCVINLVCNPSSKLLSKSTTQPLCQWTEIPGHPG LVCAMMQSLNNPVIFMIKPDGYMAQEIKAQNAKAKIMDMVAIRHSVSGVEKTTLILLCED GSLRIYAAHPENTGYWLSPEVQPIGHQQSFGWFGSGGSMYGKSARKSKKMGKQTGHGVNA TASATGKGSAGSTPNFPIDFFEHCTLMNEVEYGGNDLLQIYNTQHLKHRLNSTGLYVTST KANGFMLEVSNNDPNMVITGVRIQIGSQDVTKAPQRVTILGRSVTTIATRARWFDIPLTR EESLQSDKKLTLHFGPSVDAEQITILDSIKIYGKTKDVFGWPEETEDAAGGPITNGSSGN NGPTPAANGNGGNEGTSNDENDVGAMYMTSLDRMLSSMLHVLDSGISLLGGPNCDDNYRQ TAIDVATNLILFPTVNVVQQDARNVLMTCHANKAAYHTYKDKEILNDIHRQLKKMYESTE SGDIDPEAFYRAVLMMRSIAIQRPQAMAKICAEQQMDILSLMMILMKELYRITPAYEEPI AIVKRGLCHVEAVIYSLVEIIYAFALADSEQVERMAKLFVRLLLDSAPIISHSAKLAMIR LLRPKVKRRKVVLIESPPVCSTPTPSTSGVAVSTAGPSTSTISIGSASSGAAGPSTSSGS VASANDEFVTVAAAAAAAAAVGGMQEVDAIESLGLEPSAGNQALASLEALLGVGFPHLLE THDADDDTIMEIAIALSLQDNEADLQLLQQSIANYQGRNRNPAAQSLAAAIAGGSSFNVE SNASGGGSDDDEISNVATEGSTLRTSPAGEHAGSGSGGSESGCSGVESIGGTSGRSSTYE EQPNPSPPRTSVVEQMSSQSAGTTATAAQPSAAEAEASDSNGETANKLHVLRYSILNQLV DNFSALDTVNGAQCIPFMQVILMLTSDLDGTQEPDQQALNRLLQALIDRLEIPSTKIYQM AERTAKTEVQLLILRLIGVLMGKVKSKSSSSGNTSAATSSSADRSGLNQPLGDNASFLAQ STANALMKNNAIPYCLLIMESFLPHWKTSGASSVDELASPATSATTANASANAGSSSGGG TSNATSNNNGPVITAPGGTPSNVLLKPTQYGIIPDTQPFFARPIPKGSGDVFELYSQVLT EMAVRLPYQILKLSSGHPSSQEWNHSLCEYMTAILCEYMMYMQSPVLRRQVRKLLLYICG SKEKYRQLRDLHSLDTHMKAVKKCCELNCAQAASSSSLTNGGHSSILSYDSLVELTEHFR ACQEIASIRTGNWQKFCVRNADILSSLLNISTYQLEEGVSTIILQLLQSAICCNTSSQMQ PSKASSSSGVTVDPQMKVSVIVKDRKDRDKSEESDTISAQSESKFDAGQCVALVAQIFNQ ISPASMSKFIRSFLLETNSTSIRWQAHSLVYAFYDNCSDINKETLLQCLWSLWPLLPAYG KRTAQFVDLLGFLTLNTRSLIDKLPDYTAQAVSVLRQQNELLSKHPNAPIYTALGQVLEL EGFYLESEPCLVCNNPEVPFSNIKLSTIKVDSKFTTTTTIVKLVQSHTISKIVLRIADLK RAKMVRTINIYYNNRTVQAVVELKNRPLMWHKARKVTLQSGQTDVKIDFSLPITACNLMI EYADFYETVSGSSESLQCPRCSAVVPANPGVCGNCGENVFQCHKCRAINYDEKDPFLCHS CGFCKYAKFDYSIYGRACCAVDPIESAEDRTKTVQTIHTSLEKADRSYKSLQNNKQILEL LVQKVSEHKLDRTLDETIVGASVIGGAGGTSQVNKVIQLLAQKYCVESKTTFEDLSKIIQ KVQACRKELVAYDRSQMDAPLPGAGSMSTSFASSTGISSRTGTVALNKCYGCALASTEQC LTLLRAMASNMACRVGLCSQGLVQELAVNNLRRGTHQLQDEVRHLLCLLTRDLPDATAAL CQLLQDRVKMALSGTVPLSTLDSAVRHEMALLEAMTSQDDSCWETKLRTVIELFLQASRD ARGPATAVIHPCLRIVQSLICPPPILATTISTGGKQHGKETVATTMQDLCTVQPVEGITV SYEKWIAGDANHTFAAWKARMPPTANASATVGANRRTFGESSSVSMNTAAVTPPPIGTGF RSALEHRRATIRNAYLVEKYAKRWRQKVLAKGVLSIPVELQAAWLQPILFNTNSRLGRQL ACALITSLSRTNERKRELLDLLTSFLRYVGDSGEASAEFLALYRMLADETPWRQYLALKG VLTLLVQLVTVEIEKIHCLEETTLSTDLAQGYALRQLVELMALFLENPQIRKAYKGKLLG PVLQGYLDLRKLIVQRTRLIDDAQEKLLEMLEEMTTGTEEETAAFMAVCIDTVRRTPTTD VKTPVFMFERLCSIIHPEENDVGEFFLTLEKDPQQEDYLQGRMLGNPYPSHEAGLGPLMR DVKNKICIDCELVALLDDDNGMELLVHNKIISLDLPVKEVYKKIWLQEGGERDSLRIVYR MRGLLGDATEEFIETLNAKSQEEVDNEQLYRMANVLADCGGLKVMLERIGSLQNVSKSRT LLQVLLKLFLLSVKVSRCQEVLCQPELGAINTLLKVLQLCLQSSESDTQQSAVTEQLLEI METILSKAASDTLDTFLQFSLTFGGPEYVQALLSCTNCSNVRCNPSVLRHLIRVLAALVY GNDIKMALLCEHFRSVLDFDRFDAERSAEEEFKMELFCVLTTGIEHNSIGGTLKDYIMSL EIVEKALNYIKSHAPCVKPTLLRTDSDELKEFISRASLKYILRFLTGLATKHEATQLAVA QDIIPIIHRLEQVSSDEHVGSLAENLLEALCTEPATAKRVQEVRDFTRAEKKRLAMATRE KQLDALGMRTNEKGQVTAKGSILSQIEKLREETGLACFICREGYACQPNKVLGIYTFTKR ANVEEFEMKQKKTIGYTTVTHFNVVHVDCHMNAIRLARSRDEWESASLQNANTRCNGLLP LWGPDVSESSFSSSMARHNNYMQECTQRCEITFASSMHDLKLLLWRFAQEKSFHEDAGGG GPQSNMHLVAYLLFYGLYTLLSSRSYSREEMILSGFIGHKPSERWLECAYEAEGPLYLLT MSLALHTPDLWSRHKQVHLQRLIAIAQARHVSPNTVCKFLAPADKRPKDYNIYKPYLMFW GLIDLIYRNFFRTVGTPKDEDWPISLFNYIRRNDESLLKTADSTLQTFTEEYLPCASFGE FCDVAGLLGDIENPDAWMEELLQALPSPGGSSAAAGPSGSGATAGASNTN NT seq 16533 nt NT seq  +upstreamnt  +downstreamnt atggctgctgctcactccggaggtgttgagtgggctgcaattttaaagccttttctttcg tcatcaagtgaaaatatcagcaaaaccgatgtgttaaacttgatcaaaaccatcatacaa aatgaaaatgaaatcctcgagcacgatgccgcatacaagcagtttttcgacaatttcgtt gtgctggctgcagaaaacatcactagccaggtcacctcattgtcgcaaacacaacttcaa cagtttacggaagctgcttcaatattgattcgttacataattctacatttggatacaact gcaccatgcaaacccagcattctgttgatggccctaaagattctttgcgaagggaaaaga acgaacgaaaatcagcccaatgctaccagctcagcttcgtcaatcatttccgtgtcaggg atgaagtacttaaaatatcctgagattccgggtaacaaaccggcttcggtcggagcccca agtagtagcggaagtggaagctcagccgctggcacaagcgataaggaaagtcccaaaacg gaaatgaaacgttcgcgatcggatttgtcgacggtgatcttacaacagctaacgactcca ttgtgcagctgggctgtaacttttgctgcactcagtgaagaacaaattgactgcacggat ttgttcgtgaagcaaaatctacaatgcatgaatgctatcaatgctggagaatcgttactc aaatggtgttcgacggcgctaggaacattggccaagtatcgtttcaagtacgaagagtac accatgctgggccgaccgctttatctaccggttacaaatactgaggcgaatgctatcaaa aacatattcaatctgatggagtccgacattacaaatttgcaattggcgatctcactacct cttctggaaccgctaaccccgaagaaaatcacgctcctgtcgcagtgtgctatgtcagca ctttactgttgcgtacttacatcgaccgctgtgagtgttattactatggcatctgctgga tcgcagaagaccgcatcctctggccagttacagcaagcgcaaggacaagcaggaggaacg caaacacaaaaggaaaccgaagaggaggaagacttcgcacgaacgattgtagacaaggga ttggaaatatttacaaaaattggcaatatgctcaaaacgtctacacgtacccacatttac cagaaccacatgtgtatgggtgcatggttattgatatctggcatccaaggtacgatgggt gcttccggaaacaccagtggactgcaacagatggtgcccatttctgcgaaaacatcggaa gaaagtttgaagggacgcagtcctctaaaaacgcttgacgtaccgcaaatggcatcagct caaccgtcaccagcattgcgcgtgaatttgttcaaagttcagcaaggatttggcgtattg aatgcggccattgcacgtcacagtatcaccttgatgacggagctgatcgatgatctgaag atagactcccgtactgatgatgatgaatacagtagcatcgaatcggccggatttgatatt ctgggacagtacacatcgattcagcgcgtggtacgtgtgcttaacagtgccacgctgcaa cagctactcacattccttgctacagtgtcgtatcgtaaagcatgcacccttcgccgaatt aacaccaaaaatacaaacgatggagaaccgatgagctacagtgactcgacgacatacttt aatgatacattctcctgttcggaggagagcgaaccggaagaagaggacagcgatagctac cttggactttggttcaaagaaacgctttctccggatatgaatgaggagatgaccgaatcg caagaacaggaaaataaggatgataaaggtcgtcacggtagcaatcttgtgccggctaaa gatgaacctcacgaatatcttaatctggcctccttaattttcaacttcttcgatgtttcg ctcggcggaaatcacatctatctgagtcgttacgtgaagacaggactcagcgaacaacaa atggtactattagctaacatcttgcgcgatcttgatcgggattcggctcgcggcgaaact gatatacccggttgcatgcagtggcaaaacgccatggtaaagttttctggggccgttgga cgttatttgcataatctgatatcaaactcgctgctcaatgaatcgctacagtctgccctg ctgctgcatttgggagtatcgccatggacacaggatgcaaacatttggccattgcaggta tattcacgaacacttgccgtgctggtacaaattcttttgctgaaaccgtcacaggaaaaa gaagcagcttgtctgtctgtgtggcatcgtcttgtgaacacgatcgtggaaggtatttgt tccacccaaaccatccctaacgaatcagagatagaagatctcaacgtggagcatgctcag ctgctgctttttctgttccattcactcaacctgatgcaaaagaaatctatacttctgctt acggcagggggagttatacgctgctcggaggtatgtcgcagtgtcacacccgataaaccg ttgagagatcaccagatcatgctactgtcccggttactgctgttcctggaatatctgatg aaacatctgtacaatccaccaaacgttttgctggagcaagtgcgttggaacttgttcagt gtgtttacgctggatagtgaacaaaaattggctgatttggtaaactacaaaacgaaaatg atgtcattctgtcgaaaggacatcgaagacaagcaccgtaagctggcaaacgagtttagt gttggtggcgtgaaacccaagttctactcgctgactacagtcgaatcgaaggtgcagcaa gagtttaagctcgacggtttagcctggaattttattctatgcacccccgacaagctaaaa tatccatggcttattgatgctttaattgatattctaggcataacggacatgtgccttgca cgtatcccttttcaaactttgtgcgctgtgcattattgtttcagtcttagctggaagtta ttgcttggtttgccaccatccacgcagcacgtggaagcactgatgcaggaaaagagtcca aatctacattcattgttgtggtccattcgttgcctgcatccaataacccattcgcattat ctaattgtgaacagtctcgtcaaacagggaatgtatactcagtcagcggaggcaatgtgg atccggttaacggaatatgtttccgatgtgaagtacagtttgaaaatgaccttgctcgga ctggaatcctttgcgaagagctttacgcccgatcaaccaagattgtcgaaaattattctt ctggacagtctgatgtcgcatctatttgccgtttgttgggcagaaaaagagggtgttaat gtgaaagctgtcaaaaccagcagtaatacggttgcatcatctacagcatcgtcagctaca actactaatgcctctacagcaaacactggctcttcgacggcagtcaccaacgaaagtaat actagcggagcaagttctacgacaataccgggacctgcaaacatcgttgtgtctggcgct tcaactagtacatctttaactgatgggtcgccgtctgttatctcggcagaagtttctcgt gccgatttgacaaagaacataatgcatgctttactggacgtgttggaaatagttcgtgaa tcaacctacaaaactatgttccagaatttgagtggtcaaataccgtcctgtttgattgaa ccactgattgccattgcgggcacaaagaattcgttctgttccgaacttgctcagcagcta gttagttgtatcactggtcacgataaagatgtaatagccgttgaatggcgcaagaatttg agtacgttgaccgaagaaaatttcatcagtggatcatttccggtggaattacacactctg acggtcatcgaagcacacctgactgaggtctccaaacatctgtcatactccatactgttg tctctgaagaacgctctcaaatccgcggtcaatctcatatactacatgcttccgaactac gacgatatcaagttggacgaacgtttgaaggaaatcctgatcccgatggtgttcgatttg cgtgcagaatacttgcacggaccgatcaacaaatgcttggagacgttgctgggcggagat agcaattgcgaagcatatcagctagccgcgttctcaaacatcatcaagcatagctaccaa tttctcatcgaatataccgacctgtgtgctacaggctgtgccacgaatatcgatgaatcg gtgctctgcaacattctcaaatactgggaatcgatgttagaaaaatcgaacggattgaga gcgatgcgcaactttttctatgaatcaaagtccggtaatctggtacaaattttgctatct ttcactggcaccaatatttcgcaggcgtactccacacgcgtacttcagttctttgagaag ctgtttcaagccgcagaaaaacttgatgcgcctttcgatgaggaggagctttgttcatgc atcgcagagctggcagttaccgacagtgcacgtttgaagagttggttaagtcatatccta cttggtcctggaggaatcagtgtcacaccgaacgcatccaataattcgagcaatgtacca actccgacaaatatggcaacagtatccgcgattccgagcattactgatcaactggtggga tcagcaacagcagcaggcggagtagaagctggtttatctgaaagcaacactacagctgca aatgcacccaccactaccgagggtgagcaacaggacgccatggatatcgattatgaatgc atgactaagggaagtggatggcaggcagcagcaacgagctgtggcaaggtcgctattgaa gatgcatcaggcgaaacattggaacgcaacggcaagctactccagtcactcgttaaatac atagttgcggagaatcgtatttcctcgtcagtgtcggaagccctttttcaggccctaatt caaatcgggcacaaccttctttcgccgacgcaggaagcaatagagttttctgacctcctg caggtgatgatcacccttgcagatgctggtaaaggccgtggccatggtatactgtttact gctgccattgattggttggatgtatgccggtcgcaagtgttagatgcaggaaaaaccgga tcaagtggatggagagctgcaattcagctcgataatgtgaccgctattctgaagtatatg agcgatctactgctaggactgggcgctaagggcagccgtgtattgaatccaccttgggac gaagagtcgctgctggatgcggatgacattttggaggagcttggtgctgaagaggaagat agcacagtcgacgactccgatgaggacagcctcggaaataagctctgtaccttctctatt acacaaaaggattttatgaaccagcattggtactattgtcatacgtgcaaaatggtggac ggtgtgggcgtttgttcagtgtgtgcaagagtttgccacaaaaatcatgacatcagttat gcaaagtacggtaacttcttttgcgattgtggcgctaaagaggatggttcgtgccaagcg ctaagccgacgcagcaattctggacatgccgaggattcaatattgggatcatcatcggcg gcttcaatcttgccacgctccaatgatgccgaaagcgttttgctagctagcaacttgatg agacgacgacaccctaccagtccttcacacgaaggtcccagtacaagccgtacagcacaa ggacaagcttcggagaaggagcaacaattggcaaaaatcatagaaacttcgcgtgaagca ctgaacaatcctagccaatggaaatcagtgattcgatgcattcttgtgttcttcaattcg ctaatgcccacagtcaaagaacattgtgcgagatattctcctgtgggctgttactggcgt gctaagagcgcactagagcgtttgcatcgtccggagaaatcgtatgtattgagcgacgac atcatgattgctacgcttggttcgcaggaaggtgctttcgaaaatgtacgcatgaactat tcaggtgaacaaggtcaaacgattaaacagctgctctcaacgtatctagtgcgtcgtgtg gcattgtgttgtctggcttctcctcatggcaaacgtcagcaattggccatctctcacgag aaaggaaaagttacgatactacaattatcggccctgttgaagcaagcagatgcggcaaaa cgcaagcttacgcttaccagactcgcatcggctccagtgccgtgtaccgtactttcgctc gcgtcaaacccggccaacgaagattttctagctgtgtgtggcctgaaggagtgtcacata cttacattcaccagcacgggtacagcaaatgatcacatcgtattaactcctcagcttgac acaggaaatttcatcaagcgagctatctggctaccatcttcgcagaccaaattagctctt gttacagctgattttgttaaaatctacgatttggctgacgacagctatagtccgcagtac tacttcctggtgcctagcggcaagattcgcgattgcacatttgtttacgatcaagagggt acgtactacatgctgataatgtcttcattggggtacatatatacccaaccacttagcgat gaaagcctggcaaagcatggtcctttctacgtaacaagtacgctcgaacttgatcatcca ctgataacagacgacaacggacagattctggcaggaggtgtatcgatatactactctcac gtcctgcagctgttattcttcagttatgctgctggtcgcaactttatggcaccgctcacg aacgtcaatgatggtgtcaaatgtgtcatcaacctagtttgcaatcccagctccaaattg ttgtcgaagtcaacgacacaacctctctgtcagtggactgaaatccccggtcatccgggt ttggtatgcgcaatgatgcagagccttaacaatcctgtaatcttcatgatcaagccagac ggatatatggcccaggaaatcaaggcacagaatgcaaaggcaaaaataatggatatggtc gccatccgacacagcgtttctggtgtagaaaaaacaacactgattttgctttgcgaagat ggcagtttgaggatatatgctgcacatccagagaataccggctactggttgtctccagaa gtgcaaccaatcggacatcaacaatcgttcggctggtttggatcaggaggaagtatgtat ggcaaatctgcaaggaaatcgaaaaagatgggaaaacaaactggccacggagtaaacgct actgcgtcggccaccggaaaagggagtgcggggtctactcctaatttcccgattgatttc ttcgaacattgcacgttgatgaacgaagtagaatatggtggaaacgatttactgcaaatc tacaatacgcagcacttgaaacatcgtttaaattccaccggattgtatgtgacatcaact aaagccaacggattcatgctggaagtctcaaataatgatccgaatatggtcattacaggt gttcgcatacaaattggatcacaggacgttactaaagcaccgcaacgtgtgaccatattg ggtcgatcagttacaaccatagctacaagagcccggtggtttgatataccattaacaaga gaggaaagccttcaaagtgacaaaaagctaacccttcactttggaccttcggtggatgcc gaacaaatcacgatactggacagtatcaagatatacggaaaaactaaggatgtatttggc tggccagaagaaacggaagatgccgctggagggcctataactaatggtagttctggaaac aatggaccgacgccggccgcaaatggaaatggtggcaatgagggaacttctaacgatgaa aatgatgtaggagcaatgtatatgacttcattggatcgtatgctttccagtatgctgcac gtgctggacagtggcatatccctgttaggtggaccaaattgtgatgacaactatcgccaa acagctatcgatgtagccacaaatctaatcctcttcccgaccgtgaatgtcgtacagcag gacgcacgcaacgtgcttatgacatgccacgctaacaaggcggcttaccacacgtacaaa gataaggaaatattgaacgatatacatcggcagttgaaaaaaatgtacgaatcaaccgag agtggagatattgatcctgaagccttttatcgagcagtgttgatgatgcgcagtatcgca attcaacggccgcaagctatggcaaagatatgcgccgaacaacagatggacattctttca ctgatgatgatcctcatgaaagaactgtaccgtataacaccagcatacgaagaaccgatc gcgatcgttaaacgaggactgtgccatgtggaagcggtcatttactcgctggtggaaatt atttacgcattcgctttagccgacagcgaacaggtggagagaatggcgaaacttttcgtt cggctgttgcttgattcggctccaatcataagtcatagtgcgaaactagcgatgattcgt ttattgcgaccgaaggtcaagcgccgaaaggtggtgctaatcgaaagtcctccggtctgt tccacgcctacaccctccacatcaggagttgcagtatccactgcgggaccgtcaacatcg actatatcgattggatcggcatcatccggagctgctggaccttctacttcatcgggaagc gttgcctcggctaatgatgaatttgtaacagtagctgctgcagcggctgctgcggcagcc gtcggtggaatgcaggaagttgacgcaatagaatcactgggattagaaccaagtgcagga aatcaggcccttgcttcgcttgaggctctgttgggtgtcggttttcctcatttgctcgag acgcatgatgcggacgatgatactataatggagatagcgatcgcacttagcctgcaagat aatgaagccgatctgcaacttttgcagcagagcatcgctaattatcaaggaagaaatagg aatcctgctgcacaaagcctggctgcggccattgccgggggttcttcatttaacgtcgaa tctaacgcctcaggaggtggctcggatgatgatgaaatttccaacgttgccaccgaagga tcgactctccgaacatctccggcaggtgaacatgctggtagtggtagtggtggatccgaa agtggttgtagtggcgtcgaaagtatcggtggaacttctggacgcagttcaacgtacgaa gagcaaccgaatccttcgccaccgcgcacttctgtagtcgagcaaatgagctcccaatcg gccggtactacagcaacagcagcacaaccatctgctgcagaagccgaagcatcggattca aacggagaaactgcaaacaaattgcacgtgctgcgatactccatcttgaatcagctggtg gacaacttttccgccctagacacagtaaatggcgcacagtgcataccgtttatgcaggtt atcttaatgcttacctctgatctagatggtacccaggaaccggatcagcaagctttgaac cgtttgctgcaagcattaatcgaccgactagaaattccatcaacgaaaatttatcaaatg gctgaaagaacggcaaaaaccgaagtacagcttctcattctacgtctgattggtgtgttg atgggaaaagtgaaatcaaaatcatcctcctctggcaacacttcggcagctactagctcg agtgcggataggtcgggtctgaaccaacccttaggcgacaacgcatcatttttggcccaa agcactgctaacgctttgatgaaaaacaatgctatcccgtattgtctactgataatggaa tcctttttgccccattggaaaacctccggtgcatcatcagtcgacgagttggcttcaccg gcaacaagtgcaaccaccgccaatgcttcagcgaatgctggttcgtccagtggtggcggg acgtcaaatgcgacatcaaataataacggtccggtaataacagcaccgggaggcactcca tcgaacgttctactgaaaccgacacaatatggcattatacccgatacacaaccgtttttt gcgagacccataccgaaagggtcaggcgatgtgtttgagttgtactcgcaggtgcttacc gagatggcggttagactgccgtatcaaatattgaaactttcctcgggtcatccgtcgtct caagaatggaatcattcgttgtgcgagtacatgactgctattctctgtgagtacatgatg tacatgcagtcaccagttttacgtcgacaagttcgcaaactgttgttgtatatctgtggc agcaaggaaaagtatcggcagttgcgcgatctccactcgcttgatacgcacatgaaggca gtaaagaaatgctgtgagctgaattgtgctcaagccgcatcatcttcatcactaacgaat ggtggccattcgagtattctcagttacgactcgttagtcgaactgacggagcatttccgc gcgtgtcaggagatagcatctattcgaaccggaaactggcaaaagttctgcgtccgtaat gctgacatactttcttcacttttgaacatcagtacctaccagcttgaagaaggtgtttcg acgattattttgcaacttctgcaatcagctatatgctgcaacacttcatcacagatgcaa ccatcaaaagcatcatcttcgtctggcgtgacggtggatccacaaatgaaagtatcggtc attgtgaaggacaggaaagatcgcgacaaatcggaagaatcggacacgatttcagcgcag tcagaatctaaattcgatgcggggcaatgtgtagcgctagtggcacaaattttcaatcag atcagtcccgctagcatgagcaaattcatccgcagcttcctgctcgaaacgaactcaacg tcgattcgctggcaagcgcacagtctcgtgtatgcattctacgataactgcagcgacatc aataaggaaacgctgctgcagtgtctctggagtttgtggccattgctaccagcttacgga aagcgcactgcgcagtttgttgatttacttgggttcctcacgctcaacacacgttcgttg atagacaagctaccggactacacggcacaggcggtatcagtgctgcggcagcagaacgag ctgctctccaaacacccgaatgcccctatctacaccgctttgggacaagtgttggaactc gaaggattctatctcgaatcggaaccatgtcttgtttgtaataatccggaggttccattt tccaatatcaaactgtcaaccataaaggtggactccaagtttaccaccactacaacgatc gtgaagctggtgcaaagtcacacgatttcgaagatagtgctacgtatcgctgatctgaag cgagccaaaatggtgcgtacaatcaatatctactacaacaatcgcactgtgcaagcagtg gtagagctgaagaatcgccctctgatgtggcacaaagcccgcaaagtgacgctgcagtca ggtcaaacggacgtgaaaatcgacttctcgcttccaataacagcgtgcaatttgatgatc gagtacgctgacttttatgaaacagtaagtggatccagcgaaagtctgcagtgtccccgt tgcagtgcagtagtacctgcgaatccaggcgtgtgtggtaactgcggcgagaatgtgttc cagtgtcacaaatgtcgcgccatcaactacgacgagaaagacccgttcctatgtcattcg tgcggcttctgcaaatatgcgaaatttgattacagtatctatgggcgagcgtgttgcgct gtggatccgatcgaatcggccgaagatcggacaaaaactgtgcaaacaatacacacatcg ctggaaaaagctgaccgttcctataaatcgctgcaaaacaataagcagatattggaactg cttgttcagaaagtgtccgagcataagctcgatcgtacactcgatgaaacaatcgtggga gcttcggttattggtggagcaggaggaacttcacaggtcaacaaagtcatacagctgctg gcccaaaagtactgtgtggaatccaaaaccacctttgaagacctcagcaaaattatccaa aaagtgcaggcatgccgtaaggagttggtagcgtacgatcgaagccaaatggatgcacca ctacctggggctgggtctatgtcaacgagctttgcctccagtactggaatatcctccaga acagggacggttgcattgaataagtgttacggttgtgcccttgcatccaccgaacaatgt ctcacattgttgcgggctatggcctccaatatggcctgtagagttggattatgcagtcaa ggtttggtgcaagagctggcagtaaataatttacgccgtggaactcatcaactgcaggac gaggtgcgtcatttgctgtgtttattaacacgcgaccttcccgacgcaactgcagcgttg tgtcaattgttgcaagatcgagttaagatggcactttccggtactgttccactgtcaacg ttagattcggcagttcgacacgaaatggcactgctggaagcgatgacaagccaggacgat agctgctgggaaacgaaactacgcactgttatcgaactgttcctacaggcctcacgagat gcccgaggtccagcgactgctgtcattcatccgtgtttgcgtattgtgcaatcacttatc tgtccgccgccgatacttgcaacaacgatctccactggaggcaagcagcacggtaaagaa acagttgcaaccacgatgcaagatttgtgcacagtacagccagtcgaagggattactgtc agctacgaaaaatggatcgcaggagacgcaaatcatacgtttgctgcctggaaagctcga atgcctccgacagctaatgcaagcgctacagtgggcgccaatcgccgtacgtttggcgaa agttcatcggtttctatgaacactgcggcagtaacaccacctccaatcggaactggattc cgatcagccctggaacatcggcgagctactataagaaatgcgtatcttgtggaaaagtac gctaaacgatggcggcaaaaggttttggctaaaggagttttatcaattccggtggagtta caagcggcttggctgcaacctatcctctttaataccaattcgcgtcttggacggcagtta gcctgtgctctcattacatcgcttagtcgcacaaacgaacgcaagcgggaacttcttgat ctgctaactagttttctacgctacgtcggtgatagtggagaagcgagtgctgaatttttg gctctttaccgtatgctggcggatgaaacgccatggcgacaatatcttgcgctgaagggc gtcctaacactgcttgttcaactggtgactgtagaaattgagaagatccattgcctagaa gaaacgacactttcaaccgatctagctcaaggatatgcattacggcagttggtggagctt atggcacttttcttagaaaatccgcaaattcgcaaagcgtacaagggcaaactgttggga ccggtgcttcagggctatctcgatcttcgtaagctgattgtacaacgcacacgtttaatc gatgatgcgcaagagaagctgctagaaatgctggaggaaatgactacgggaacggaagaa gaaactgccgcatttatggcggtttgcattgacacggtgcggcgtacaccaaccacggac gtaaaaacaccggtcttcatgttcgagcgattgtgctccataatccatccggaggaaaac gatgtgggtgaatttttcctcacgctagagaaagatcctcagcaagaggattacctgcag ggccgtatgctgggaaatccatatccttcccatgaggcaggtctgggcccactgatgcgt gatgttaaaaacaaaatctgtatcgactgcgaactggtggctttgctggacgacgacaat ggtatggagttgttggttcacaacaaaatcataagcctagatctgccggtaaaggaagtg tacaagaaaatttggcttcaagaaggcggagaacgagacagtttgcgaatcgtctatcga atgcgtggtttgctgggtgatgcgaccgaagagttcatagagacactaaatgccaagagc caagaggaggttgataacgaacaattgtaccggatggcgaatgtgttggccgattgtgga gggcttaaagtgatgttagaacgtatcggaagcttgcagaacgtatcgaaatcccgcacc ttactgcaggttctgttgaaattgttcctgctaagcgtgaaggtgtcccgttgccaggag gtactttgccaaccggaactgggggccataaacacgcttttgaaggtgttacaattgtgt ctgcaaagcagtgagagcgatacgcagcagtctgccgtaacggagcaattgttggagatc atggaaacgattttgtccaaggctgcttccgacacgttggacacgtttttgcaattttca cttacgttcggagggccggagtacgtgcaagcactactatcgtgcaccaattgctccaac gtacgctgcaatccttctgtactgcggcacctgatccgtgtgcttgcagctctagtgtac ggaaatgacatcaagatggcgctcctgtgcgaacatttccgatccgtgctcgatttcgat cgattcgatgcggaacgcagtgccgaggaagagttcaagatggagctgttttgtgtactg accaccggtatcgagcacaattccatcggtggaacgctgaaagactacatcatgagtttg gaaatcgtggagaaagcactcaactacatcaagtcccatgcaccgtgtgtgaaaccgacg ctgctgcgcaccgactcggacgagttgaaggaattcatatcgcgagcctcactcaagtac atcctccgtttccttaccggtctagcgacaaagcacgaagcgacgcagctagcagttgcg caggatataattccgatcatccatcgcctggaacaagtgtcaagcgacgagcacgttgga tcgcttgcagagaatcttctggaggcattgtgcactgaaccggcgaccgcgaagcgtgtc caagaggtgcgcgattttacgcgcgctgagaaaaagcgacttgcaatggcgacccgcgag aaacagttggacgcccttggaatgcgtacgaacgaaaaggggcaggttacagcgaagggt tcgatcctctcgcagattgaaaaactgcgcgaagaaacaggcctggcgtgtttcatatgc cgcgaagggtacgcctgccaaccgaacaaagtgctcggcatctatacttttaccaagcgc gcaaacgttgaggagtttgagatgaagcaaaagaagacgatcggttacactacggtgaca catttcaacgtcgtgcacgtggactgtcacatgaacgcgatcagattggcccgatctcgt gacgagtgggagagtgcatcgctgcagaatgcaaacacacgctgcaatggattgcttccg ttgtgggggccagatgtgagtgaatcttcattctcgtcgtcgatggcacgccacaacaac tacatgcaggaatgcacgcaacgatgtgaaatcaccttcgctagctcgatgcacgatctg aagctgctactttggcgctttgctcaggaaaaaagcttccacgaggatgcgggtggtggt ggaccacagtcgaacatgcatctggtagcatatctgctattttatggactgtacacgttg ctctcgtctcgttcatactcgcgagaagagatgatactcagtggtttcattggccacaaa ccctcggaacgttggttggagtgtgcttacgaagcggaaggcccactgtatctgctcacc atgtcattggctttgcatacacccgacttgtggtcacgccataagcaagtacatcttcag cgtctgattgcgatcgcacaggctcggcacgttagcccaaatacagtttgcaaattcttg gcaccagccgacaaacgcccaaaggattacaacatctataagccgtatctcatgttctgg ggactgatcgatttgatctatcgcaactttttccgcaccgttgggacgccgaaggatgaa gactggccgatctcgctatttaactacattcgccgaaacgatgagtcgttgctcaagacg gccgactctacgttgcaaacattcaccgaagaatatctgccttgtgcttcgtttggtgaa ttttgcgatgtagcaggactacttggagacatcgagaatcccgatgcttggatggaagag ctactgcaagcattgccttcaccgggcggttcatctgcagctgcaggtccaagtggttcc ggagcgactgctggagccagcaatacgaattag

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