Amycolatopsis methanolica: AMETH_0916
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Entry
AMETH_0916 CDS
T03230
Symbol
rfbB
Name
(GenBank) dTDP-glucose 4,6-dehydratase
KO
K01710
dTDP-glucose 4,6-dehydratase [EC:
4.2.1.46
]
Organism
amq
Amycolatopsis methanolica
Pathway
amq00521
Streptomycin biosynthesis
amq00523
Polyketide sugar unit biosynthesis
amq00525
Acarbose and validamycin biosynthesis
amq00541
Biosynthesis of various nucleotide sugars
amq01055
Biosynthesis of vancomycin group antibiotics
amq01100
Metabolic pathways
amq01110
Biosynthesis of secondary metabolites
amq01250
Biosynthesis of nucleotide sugars
Module
amq_M00793
dTDP-L-Rha biosynthesis, Glc-1P => dTDP-L-Rha
Brite
KEGG Orthology (KO) [BR:
amq00001
]
09100 Metabolism
09107 Glycan biosynthesis and metabolism
00541 Biosynthesis of various nucleotide sugars
AMETH_0916 (rfbB)
09109 Metabolism of terpenoids and polyketides
00523 Polyketide sugar unit biosynthesis
AMETH_0916 (rfbB)
01055 Biosynthesis of vancomycin group antibiotics
AMETH_0916 (rfbB)
09110 Biosynthesis of other secondary metabolites
00521 Streptomycin biosynthesis
AMETH_0916 (rfbB)
00525 Acarbose and validamycin biosynthesis
AMETH_0916 (rfbB)
Enzymes [BR:
amq01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.46 dTDP-glucose 4,6-dehydratase
AMETH_0916 (rfbB)
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Motif
Pfam:
GDP_Man_Dehyd
Epimerase
Polysacc_synt_2
3Beta_HSD
NAD_binding_4
RmlD_sub_bind
NAD_binding_10
NmrA
adh_short
Motif
Other DBs
NCBI-ProteinID:
AIJ21008
UniProt:
A0A076MJI1
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Position
930516..931508
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AA seq
330 aa
AA seq
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MRVLVTGGAGFIGSHYVRQVLSGAYPALADAEVVVLDKLTYAGNEANLAPVADSPRLRFV
RGDITDAQVVAEVMKGVGLVVHFAAESHVDRSILGSADFVLTNVLGTQTLLQAALDAGVD
KFVHVSTDEVYGSIESGSWSEDHVLEPNSPYSASKASSDLIARSYFRTHGLPVCVTRCSN
NYGPYQFPEKVIPLFVTNLLDGHTVPLYGDGLNVRDWLHVDDHCAGIQLVAEGGRPGEIY
NIGGGTELTNRELTERLLAAVGVGWERVEQVADRKGHDRRYSVDITKISTELGYAPKVSF
DAGLADTVRWYADNRAWWEPLKRRAALVGK
NT seq
993 nt
NT seq
+upstream
nt +downstream
nt
atgcgggtcctggtgaccgggggcgcgggtttcatcggctcgcactacgtccggcaggtg
ctctccggcgcgtacccggcgctggccgacgccgaggtggtggtgctcgacaagctcacc
tacgcgggcaacgaagcgaacctcgcgccggtcgcggactcgccgcggctgcggttcgtg
cggggcgacatcaccgatgcgcaggtggtcgccgaggtcatgaaaggcgtcggcctggtt
gtccacttcgcagccgagtcgcatgtggaccgctccatcctcggctccgccgacttcgtg
ctgaccaacgtgctgggcacgcagaccctgttgcaggccgcgctggacgccggggtggac
aagttcgtgcacgtctcgacggacgaggtgtacggctcgatcgaaagcggatcatggtcg
gaagaccacgtgctggagccgaattcgccgtactcggcgtcgaaggcgtcctccgatctg
atcgcgcggtcctacttccggacgcacgggctgcccgtgtgcgtgactcggtgttcgaac
aactacgggccgtatcagttcccggagaaggtcatcccgcttttcgttaccaacttgttg
gacggtcacacggtcccgctgtacggcgacgggctgaacgtccgtgactggttgcacgtg
gacgatcactgcgcgggcatccagctggtggccgagggcggccgtcctggcgagatctac
aacatcggcgggggcaccgagctgaccaaccgcgagctgaccgagcggctgctggccgcg
gtcggcgtcggctgggagcgggtcgagcaggtcgccgaccgcaagggccacgaccgccgg
tactccgtggacatcaccaagatcagcaccgagctcggatacgcgccgaaggtttccttc
gacgcgggtctggcggatacggtgcgctggtacgccgacaatcgggcgtggtgggagccg
ttgaagcggcgcgccgcgctggtggggaagtga
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