Amycolatopsis methanolica: AMETH_1022
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Entry
AMETH_1022 CDS
T03230
Symbol
hemD
Name
(GenBank) Uroporphyrinogen III synthase HEM4
KO
K01719
uroporphyrinogen-III synthase [EC:
4.2.1.75
]
Organism
amq
Amycolatopsis methanolica
Pathway
amq00860
Porphyrin metabolism
amq01100
Metabolic pathways
amq01110
Biosynthesis of secondary metabolites
amq01120
Microbial metabolism in diverse environments
amq01240
Biosynthesis of cofactors
Module
amq_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
amq_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
amq00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
AMETH_1022 (hemD)
Enzymes [BR:
amq01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
AMETH_1022 (hemD)
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Gene cluster
GFIT
Motif
Pfam:
HEM4
Motif
Other DBs
NCBI-ProteinID:
AIJ21114
UniProt:
A0A076MK81
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Position
1030924..1031730
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AA seq
268 aa
AA seq
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MGDLSGVTIGVTAERRAEEFIGALERNGATVRHAPLIHIVPLPDDARLRAATEEVLAEPL
DVLAVTTGAGFGGWIEAAEGWGLRDDLLASLTRARVFVRGPKGKGAVRGVGLTEEWAAPE
ESNRQLFGHLLEAGVAGARLAVQLHGTPLPEHTAPLREAGARLIEVQPYRWEWPADLHPA
HELLDGVLDGRIDALAFTSAPASANMLNLARERGAYDDLVRALRGDVVCACVGPVTAAPF
TDAGVPTLQPERQRLGALVKLLVAELGT
NT seq
807 nt
NT seq
+upstream
nt +downstream
nt
atgggtgacttgagcggagtcacgatcggggtgaccgcggagcggcgggccgaggagttc
atcggtgcgctggaacgcaacggcgccacggtgcggcacgcgccgttgatccacatcgtg
ccgctgcccgacgacgcccggttgcgcgccgcgaccgaggaggtcctcgccgagccgctg
gacgtcctcgcggtcaccaccggcgccggattcggcggctggatcgaggccgccgagggg
tggggactgcgcgacgacctgctcgcatcgctgaccagggcgcgggtgttcgtccgcgga
ccgaagggcaagggcgcggtgcggggcgtcggactcaccgaggagtgggccgcgcccgag
gagagcaaccggcagctgttcgggcacctcctggaggccggtgtcgccggcgcgcggctg
gcggtccagctgcacggcacgccgctgcccgagcacaccgctccactgcgcgaggccggc
gcgcggctgatcgaggtgcagccgtaccggtgggagtggcccgccgacctgcacccggcg
cacgagctgctggacggcgtgctcgacggccggatcgacgcgctggcgttcaccagcgcc
ccggcgagcgcgaacatgctgaacctggcccgggaacgcggcgcctacgacgacctggtg
cgcgccttgcggggcgacgtcgtgtgcgcctgcgtcgggccggtgaccgccgcgccgttc
accgacgccggggtgccgaccttgcagccggagcggcagcggctcggcgcgctggtcaag
ctgctggtggcggagctgggcacctag
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