Amycolatopsis methanolica: AMETH_1513
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Entry
AMETH_1513 CDS
T03230
Symbol
leuA
Name
(GenBank) alpha-isopropylmalate/homocitrate synthase family transferase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
amq
Amycolatopsis methanolica
Pathway
amq00290
Valine, leucine and isoleucine biosynthesis
amq00620
Pyruvate metabolism
amq01100
Metabolic pathways
amq01110
Biosynthesis of secondary metabolites
amq01210
2-Oxocarboxylic acid metabolism
amq01230
Biosynthesis of amino acids
Module
amq_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
amq00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
AMETH_1513 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
AMETH_1513 (leuA)
Enzymes [BR:
amq01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
AMETH_1513 (leuA)
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GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
Motif
Other DBs
NCBI-ProteinID:
AIJ21605
UniProt:
A0A076MS27
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All DBs
Position
1544129..1545730
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AA seq
533 aa
AA seq
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MTRTEPAGLPLGDDFHLYDTTLRDGAQREGISYSVADKLAVARLLDELGVGFIEGGWPGA
LPKDTEFFARAADGELILKHAALVAFGSTRKAGTTAAEDAQVRALLDSRAPVVTLVAKSD
RRHIERALRVDVDEACAMVADTVSFLVGEGRRVFLDAEHFFDGYAFDPDTSLRVLEAGFT
AGADVVVLCDTNGGQLPLGIAETVREVAARTGFRLGIHCQDDTSCAVANSIAAVQAGATH
VQCTANGYGERAGNADLFAVTGNLVAKLGMDVLPTGGAAELTRVSHALAEIANIAPDTHQ
AYVGSSAFAHKAGLHASAIKVDPLLYNHIDPSSVGNDMRVLVTEMAGRASLELKGRELGV
DLAGRPEAVTSVVAKVKELEAEGWSFEAADASLELLLREEVDGPAEPPFTLESYRVVLDH
RGDGEVISEATVKVHVAGERVIATAEGNGPVHALDAALRKALSPSLSWLDSVELSDYKVR
ILPSHPGSDAVTRVLLKSSDGDQEWTTVGVHGSIVEASWLALCDALVHKSMRA
NT seq
1602 nt
NT seq
+upstream
nt +downstream
nt
gtgacccgcacggagccagccggactgcctctcggtgacgacttccacctgtacgacacg
actttgcgggacggcgcccagcgcgagggcatctcctactcggtggcggacaagctcgcc
gtcgcgcgtctgctggacgagctgggtgtgggcttcatcgagggcggctggccgggagcg
ttgccgaaggacaccgagttcttcgcccgcgccgcggacggggagctgatcctcaagcac
gcggcgctcgtcgcgttcggatcgacgcgcaaggcgggcacgacggcggcggaggacgcc
caggtgcgggcgctgctcgactcgcgggcgcccgtggtgacgctggtcgcgaagtcggac
cgccgccacatcgagcgcgcgttgcgcgtggacgtcgacgaggcctgcgcgatggtcgcc
gacaccgtgtcgttcctggtcggcgaggggcgccgggtgttcctcgacgccgagcacttc
ttcgatggctacgccttcgacccggacacctcgctgcgcgtgctggaagccgggttcacc
gcaggcgccgacgtcgtcgtgctgtgcgacaccaacggcggccagctgccgctcgggatc
gccgaaacggtgcgggaagtcgccgcccgcaccggtttccggctcggcatccactgccag
gacgacacttcctgcgccgtcgccaacagcatcgcggcggtgcaggccggcgcgacgcac
gtgcagtgcaccgcgaacgggtacggggagcgggccggcaacgccgacctgttcgccgtg
acgggaaacctcgtggccaagctcgggatggacgtgctccccaccgggggcgccgccgag
ctgacccgcgtctcccatgcccttgccgaaatcgcgaacatcgcacccgacacccaccag
gcctacgtcgggtcgtcggccttcgcccacaaggcggggctgcacgcgagcgcgatcaag
gtggatccgttgctgtacaaccacatcgatccatcttccgtcggcaacgacatgcgggtc
ctggtcaccgagatggccggcagggccagcctggagctcaagggacgtgagctcggggtg
gaccttgccggccggcctgaggcggtcaccagcgtggtggcgaaggtgaaggagctggag
gccgagggctggtcgttcgaggccgccgacgcgtcgctggaactgctgctgcgcgaggag
gtcgacggcccggccgagccgccgttcacgctggagtcctaccgcgtcgtgctggaccac
cgcggcgacggggaggtgatctccgaggcgacggtgaaggtgcacgtcgcgggggagcgg
gtgatcgcgaccgcggagggcaacggcccggtgcacgcgctggacgctgcgctgcggaag
gccctgtcgccgtcgctgtcctggttggacagtgtcgagctgtcggactacaaggtgcgg
atcctgccgagccacccgggcagcgacgcggtgacccgggtgctgctgaagtccagcgac
ggcgaccaggagtggaccacggtcggcgtgcacggcagcatcgtcgaagcgagctggctc
gccttgtgcgacgcactggtgcacaagagcatgcgggcctag
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