Amycolatopsis methanolica: AMETH_1526
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Entry
AMETH_1526 CDS
T03230
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
amq
Amycolatopsis methanolica
Pathway
amq00290
Valine, leucine and isoleucine biosynthesis
amq00660
C5-Branched dibasic acid metabolism
amq01100
Metabolic pathways
amq01110
Biosynthesis of secondary metabolites
amq01210
2-Oxocarboxylic acid metabolism
amq01230
Biosynthesis of amino acids
Module
amq_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
amq00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
AMETH_1526 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
AMETH_1526 (leuC)
Enzymes [BR:
amq01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
AMETH_1526 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
AMETH_1526 (leuC)
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GFIT
Motif
Pfam:
Aconitase
AcnX
Motif
Other DBs
NCBI-ProteinID:
AIJ21618
UniProt:
A0A076MLG5
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Position
1559074..1560489
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AA seq
471 aa
AA seq
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MTTTRPRTLAEKVWEAHTVRRGEGAEPDLLYIDLHLVHEVTSPQAFDGLRLAGRKVRRPD
LTIATEDHNVPTVDIELPIADPVSRTQVETLRKNCKEFGVRLHPMGDAEQGIVHVIGPQL
GLTQPGMTVVCGDSHTSTHGAFGAMAFGIGTSEVEHVLATQTLPLRPFKTMAINVDGRLR
PGVTAKDVILAVIAKIGTGGGQGYVLEYRGSAIEALSMEARMTICNMSIEAGARAGMIAP
DETTFAYLKGRPHAPQGADWDAAVENWKSLRTDEGAVFDAEVHLDADSLTPFVTWGTNPG
QGLPLSESVPDPEQIADETERFAAEKALSYMDLKPGTPLRDIKVDTVFLGSCTNGRIEDL
RAAADVLQGRKVAEGVRMLVVPGSMRVRQAAEAEGLDKVFLDAGAEWRQAGCSMCLGMNP
DQLAPGERSASTSNRNFEGRQGKGGRTHLVSPLVAAATAVRGTLSSPEDLN
NT seq
1416 nt
NT seq
+upstream
nt +downstream
nt
atgaccaccacgcggccgcggacactggccgagaaggtgtgggaggcgcacaccgtgcgc
cgcggtgaaggagcggagcccgacctgctctacatcgacctgcacctggtgcacgaagtc
accagcccgcaggcgttcgacggtctccggctggccggccgcaaggtgcggcgcccggac
ctgaccatcgcgaccgaggaccacaacgtcccgaccgtcgacatcgaactcccgatcgcc
gacccggtgtcccgcacccaggtcgagacgcttcggaagaactgcaaggagttcggcgtc
cggctgcacccgatgggcgacgccgagcagggcatcgtgcacgtcatcggcccgcagctg
ggcctgacccagcccgggatgacggtcgtctgcggtgacagtcacacctccacccacggc
gcgttcggcgcgatggccttcggcatcggcacctccgaggtcgagcacgtgctggccacc
cagaccctgccgctgcggccgttcaagacgatggcgatcaacgtcgacggcaggctccgg
ccgggtgtcacggcgaaggacgtcatcctcgccgtcatcgccaagatcggcaccggcggc
ggccagggctacgtcctggagtaccggggcagcgcgatcgaggcgctgtcgatggaagcc
cgcatgacgatctgcaacatgtcgatcgaggcgggcgcgcgcgccgggatgatcgccccg
gacgagaccaccttcgcctacctgaagggccgcccgcacgccccgcagggcgccgactgg
gacgccgcggtggagaactggaagtcgctgcgcaccgacgagggcgccgtcttcgacgcc
gaggtccacctcgacgccgactccctgaccccgttcgtgacgtggggcaccaaccccggc
cagggcctgccgctgagcgagtcggtgccggacccggagcagatcgcggacgagaccgag
cggttcgccgccgagaaggccctgtcctatatggacctcaagccgggcaccccgctgcgt
gacatcaaggtcgacaccgtcttcctcggctcgtgcaccaacggccggatcgaggacctg
cgggcggccgcggacgtgctccagggccgcaaggtggccgagggcgtccggatgctcgtc
gtgcccggctcgatgcgggtgcgccaggccgccgaggccgaggggctggacaaggtcttc
ctcgacgccggcgcggagtggcgccaggcgggctgctcgatgtgcctcggcatgaacccg
gaccagctggcccccggcgagcgcagcgcgtccacctccaaccgcaacttcgagggcagg
cagggcaagggtggccgcacccacctcgtctcgccgctcgtcgcggccgccacggccgtc
cgcggcacgctgtccagccccgaagacctgaactga
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