Amycolatopsis methanolica: AMETH_2573
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Entry
AMETH_2573 CDS
T03230
Symbol
rfbB
Name
(GenBank) NAD-dependent epimerase/dehydratase
KO
K01710
dTDP-glucose 4,6-dehydratase [EC:
4.2.1.46
]
Organism
amq
Amycolatopsis methanolica
Pathway
amq00521
Streptomycin biosynthesis
amq00523
Polyketide sugar unit biosynthesis
amq00525
Acarbose and validamycin biosynthesis
amq00541
Biosynthesis of various nucleotide sugars
amq01055
Biosynthesis of vancomycin group antibiotics
amq01100
Metabolic pathways
amq01110
Biosynthesis of secondary metabolites
amq01250
Biosynthesis of nucleotide sugars
Module
amq_M00793
dTDP-L-Rha biosynthesis, Glc-1P => dTDP-L-Rha
Brite
KEGG Orthology (KO) [BR:
amq00001
]
09100 Metabolism
09107 Glycan biosynthesis and metabolism
00541 Biosynthesis of various nucleotide sugars
AMETH_2573 (rfbB)
09109 Metabolism of terpenoids and polyketides
00523 Polyketide sugar unit biosynthesis
AMETH_2573 (rfbB)
01055 Biosynthesis of vancomycin group antibiotics
AMETH_2573 (rfbB)
09110 Biosynthesis of other secondary metabolites
00521 Streptomycin biosynthesis
AMETH_2573 (rfbB)
00525 Acarbose and validamycin biosynthesis
AMETH_2573 (rfbB)
Enzymes [BR:
amq01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.46 dTDP-glucose 4,6-dehydratase
AMETH_2573 (rfbB)
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Motif
Pfam:
Epimerase
GDP_Man_Dehyd
3Beta_HSD
Polysacc_synt_2
RmlD_sub_bind
NAD_binding_4
adh_short
NAD_binding_10
Sacchrp_dh_NADP
UDPG_MGDP_dh_N
Motif
Other DBs
NCBI-ProteinID:
AIJ22665
UniProt:
A0A076MVD5
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All DBs
Position
2673622..2674560
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AA seq
312 aa
AA seq
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MPGHAVVTGGAGFVGSHLCERLLARGLRVTCVDNLSTGRADNIAHLHGDFHFVEADVARG
LDITGHVDLVLHLASPASPRDYERLPVETLQVGAVGTGHALDLAQANGARFVLASTSEVY
GDPREHPQRETYWGNVNPVGPRSVYDEAKRYAEALTAACRRARGVNTGIARIFNTYGPRM
RADDGRAIPTFVKQVLTGEPVTVAGEGAQTRSLCYVDDTVDGLLALADSDFPGPVNLGNP
HELRIRDLVGEIQRLAGTSVLVRGIPAPVDDPQRRCPDIAVAQRELGWQPRVELHEGLRR
TLKWFATHLSLV
NT seq
939 nt
NT seq
+upstream
nt +downstream
nt
gtgccagggcatgcggtcgtcacgggtggagcgggcttcgtcggctcccacctctgcgag
cgcctgctcgcccgcggcctgcgcgtcacctgcgtggacaacttgtccaccggccgcgcg
gacaacatcgcgcacctgcacggcgacttccacttcgtcgaggccgacgtcgcgcgtgga
ctggacatcaccggccacgtcgacctggtgctgcacctggccagccccgcctcgccacgc
gactacgagcgcctgccggtggagacgctgcaggtcggtgcggtcggcaccggccacgcg
ctggacctcgcgcaggccaacggcgcccggttcgtgctggcgtcgaccagtgaggtctac
ggcgacccgcgggaacacccgcagcgcgagacctactggggcaacgtcaacccggtcggc
ccgcgcagcgtctacgacgaggccaaacgctacgccgaagccctcaccgccgcctgccgc
cgagcccgcggcgtgaacaccggcatcgcccgcatcttcaacacctacggcccccgcatg
cgcgccgacgacggccgcgcgatcccgacgttcgtcaagcaggtcctcaccggcgagccg
gtcaccgtcgcgggtgagggcgcccagacccgctccctgtgctatgtggacgacaccgtc
gacggcctgctggcgctggcggacagcgatttcccggggccggtcaacctcggcaacccg
cacgaactccgcatccgggacctggtcggggaaatccagcggctggcgggcaccagcgtg
ctggtgcgcggcatccccgccccggtggacgatccgcaacgacgctgccccgatatcgcg
gtggcgcaacgggaactgggctggcagccgcgggtggagctgcacgagggtctgcgccgg
accctgaagtggttcgcgacccacctcagtctcgtttag
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