Anopheles marshallii: 128709389 Help Entry 128709389         CDS       T10928                                  Name (RefSeq) protein purity of essence   KO K10691   E3 ubiquitin-protein ligase UBR4 [EC:2.3.2.27] Organism amrs  Anopheles marshallii Brite KEGG Orthology (KO) [BR:amrs00001]  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04121 Ubiquitin system [BR:amrs04121]     128709389 Enzymes [BR:amrs01000]  2. Transferases   2.3  Acyltransferases    2.3.2  Aminoacyltransferases     2.3.2.27  RING-type E3 ubiquitin transferase      128709389 Ubiquitin system [BR:amrs04121]  Ubiquitin ligases (E3)   Single Ring-finger type E3    UBR box proteins     128709389 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  E3_UbLigase_R4 E3_UBR4_N UBR4 zf-UBR Motif Other DBs NCBI-GeneID:  128709389 NCBI-ProteinID:  XP_053660361 LinkDB All DBs Position 2:complement(1354535..1372157) Genome browser AA seq 5518 aa AA seqDB search MAAAHSGGVEWAAILKPFLSSSSENISKTDVLNLIKTIIQNENEILEHDAAYKQFFDNFV VLAAENITSQVTSLSQTQLQQFTEAASILIRYIILHLDTTAPCKPSILLMALKILCEGKR ANENQPNATSSASSIISVSGMKYLKYPEIPGNKPASVGAPSSSGSGGSAAGTSDKESPKT EMKRSRSDLSTVILQQLTTPLCSWAVTFAALSEEQIDCTDLFVKQNLQCMNAINAGESLL KWCSTALGTLAKYRFKYEEYTMLGRPLYLPVTNTEANAIKNIFNLMESDITNLQLAISLP LLEPLTPKKISLLSQCAMSALYCCVLTSTAVSVITMASAGSQKTASSGQLQQAQGQTGGT QTQKESEEEEDFARTIVDKGLEIFTKIGNMLKTSTRTHIYQNHMCMGAWLLISGIQGTMG ASGNTSGLQQMVPISAKTSEESLKGRSPLKTLDVPQMASAQPSPALRVNLFKVQQGFGVL NAAIARHSITLMTELIDDLKIDSRTDDDEYSSIESAGFDILGQYTSIQRVVRVLNSATLQ QLLTFLATVSYRKACTLRRINTKNTNDGEPMSYSDSTTYFNDTFSCSEESEPEEEDSDSY LGLWFKETLSPDMNEEMTESQEQENKDDKGRHGSNLVPAKDEPHEYLNLASLIFNFFDVS LGGSHIYLSRYVKTGLSEQQMVLLANILRDLDRDSARGETDIPGCMQWQNAMVKFSGAVG RYLHNLISNSLLNESLQSALLLHLGVSPWTQDANIWPLQVYSRTLAVLVQILLLKPSQEK EAACLSVWHRLVNTIVEGICSTQTIPNESEIEDLNVEHAQLLLFLFHSLNLMQKKSILLL TAGGVIRCSEVCRSVTPDKPLRDHQIMLLSRLLLFLEYLMKHLYNPPNVLLEQVRWNLFS VFTLDSEQKLADLVNYKTKMMSFCRKDIEDKHRKLANEFSVGGVKPKFYSLTTVESKVQQ EFKLDGLAWNFILCTPDKLKYPWLIDALIDILGITDMCLARIPFQTLCAVHYCFSLSWKL LLGLPPSTQHVEALMQEKSPNLHSLLWSIRCLHPITHSHYLIVNSLVKQGMYTQSAEAMW IRLTEYVSDVKYSLKMTLLGLESFAKSFTPDQPRLSKIILLDSLMSHLFAVCWAEKEGVN VKAAKTNSNTVASSATSSATASNTSTANAGSSPVVTNESNASGASSTTVSGAANIVASGP SASTSSSDGSPCVISAEVSRADLTKNIMHALLDVLEIVRESTYKTMFQNLSGQIPSCLIE PLIAIAGTKNSFCSELAQQLVSCITGHDKDVIAVEWRKSLSTLTEENFISGSFPVELHTL TVIEAHLTEVSKHLSYSILLSLKNALKSAVNLIYYMLPNYDDIKLDERLKEILIPMVFDL RAEYLHGPINKCLESLLGGDSNCEAYQLAAFSNIIKHSYQFLIEYTDLCATGCATNIDES VLCNILKYWELMLEKSNGLRAMRNFFYESKSGNLVQILLSFTGTNISQAYSTRVLQFFEK LFQAAEKLDAPFDEEELCSCIAELAVTDSTRLKSWLSHILLGPGGISVTPNASNNSSNVP TPTNMATVSAIPSITDQLVGSATAAGGVEPGLSESNTTAANAPTTTEGEQQDAMDIDYEC MTKGSGWQAAATSCGKVAIEDASGETLERNGKLLQSLVKYIVAENRISSSVSEALFQALI QIGHNLLSPTQEAIEFSDLLQVMITLADAGKGRGHGILFSAAIDWLDVCRAQVLDAGKAG SSGWRAAIQLDNVTAILKYMSDLLMGLGAKGSRVLNPPWDEESLLDADDILEELGGEEED STVDDSDEDSLGNKLCTFSITQKDFMNQHWYYCHTCKMVDGVGVCSVCARVCHKNHDISY AKYGNFFCDCGAKEDGSCQALSRRSNSGHTEDSILGPSSAASILPRSNDAESVLLASSLM RRRHPTSPSHEGPSSSRAAQGQTSEKEQQLAKIIETSREALNNPSQWKSVIRCILVFFNS LMPTVKEHCARYSPVGCYWRAKNALERLHRPEKSYVLSDDIMIATLGSQEGAFENVRMNY SGEQGQTIKQLLSTYLVRRVALCCLASPHGKRQQLAISHEKGKVTILQLSALLKQADAAK RKLTLTRLASAPVPCTVLSLASNPANEDFLAVCGLKECHILTFTSTGTANDHIVLTPQLD TGNFIKRAIWLPSSQTKLALVTADFVKIYDLADDSYSPQYYFLVPSGKIRDCTFVYDQEG TYYMLIMSSLGYIYTQPLSDESLAKHGPFYVTSTLELDHPLITDDNGQILAGGVSIYYSH VLQLLFFSYAAGRNFMAPLTNVNDGVKCVINLVCNPSSKLLSKSTTQPLCQWTEIPGHPG LVCAMMQSLNNPVIFMIKPDGYMAQEIKAQNAKAKIMDMVAIRHSVSGVEKTTLILLCED GSLRIYAAHPENTGYWLSPEVQPIGHQQSFGWFGSGGSMYGKSARKSKKMGKQSGHGVNA TASTTGKGVAGSAPNFPIDFFEHCTLMNEVEYGGNDLLQIYNTQHLKHRLNSTGLYVTST KANGFMLEVSNNDPNMVITGVRIQIGSQDVTKAPQRVTILGRSVTTVATRARWFDIPLTR EESLQSDKKLTIHFGPSVDAEQITILDSIKIYGKTKDVFGWPEETEDAAGGQLTNGSSGN NGQTAVANGNGGNEGTSNDENDVGAMYMTSLDRMLSSMLHVLDSGISLLGGPNCDDNYRQ TAIDVATNLILFPTVNVVQQDARNVLMTCHANKAAYHTYKDKEILNDIHRQLKKMYESTE SGDIDPEAFYRVVLMMRSIAIQRPQAMAKICAEQQMDILSLMMILMKELYRITPAYEEPI AIVKRGLCHVEAVIYSLVEIIYAFALADSEQVEKMAKLFVRLLLDSAPIISHSAKLAMIR LLRPKVKRRKVVLIESPPVCSTPTPSTSGVATSTAGPSTSTISIGSASSGPAGPSTSSGS IATANDEFVTAAAAAAVGGMQEVDAIESLGLEPSAGNQALASLEALLGVGFPHLLETHDA DDDTIMEIAIALSLQDNEADLQLLQQSIANYQGRNRNPAAQSLAAAIAGGSSFNVESNAS GGGSDDDEISNVATEGSTLRTSPAGEHAGSGSGGSESGCSGVESIGGTSGRSSTYEEQPN PSPPRTSVVDQMSSQSVGTTATAAHPSAAEAEASDSNGETANKLHVLRYSILNQLVDNFS ALDTVNGAQCIPFMQVILMLTSDLDGTQEPDQQALNRLLQALIDRLEIPTTKIYQMAERT ARTEVQLLILRLIGVLMGKVKSKSSSSSSSANTTAATSSSADRSGVNQPLGGDNASFLAQ STANALMKNNAIPYCLLIMESFLPHWKTSGASSVDELASPATSATTANASANAASSSGGG VSNATSNNNGPVITAPGGTPSNVLLKPTQYGIIPDTQPFFARPIPKGSGDVFELYSQVLT EMAVRLPYQILKLSSGHPSSQEWNHSLCEYMTAILCEYMMYMQSPVLRRQVRKLLLYICG SKEKYRQLRDLHSLDTHMKAVKKCCELNCAQAASSSSLTNGGHSSILGYDSLVELTEHFR ACQEIASIRTGNWQKFCVRNADILSSLLNISTYQLEEGVSTIILQLLQSAICCNTSSQMQ PSKASSSSGVTVDPQLKVSVIVKDRKDRDKSEESDTISAQSESKFDAGQCVALVAQIFNQ ISPASMSKFIRSFLLETNSTSIRWQAHSLVYAFYDNCSDINKETLLQCLWSLWPLLPAYG KRTAQFVDLLGFLTLNTRSLIDKLPDYTAQAVSVLRQQNELLSKHPNAPIYTALGQVLEL EGFYLESEPCLVCNNPEVPFSNIKLSTIKVDSKFTTTTTIVKLVQSHTISKIVLRIADLK RAKMVRTINIYYNNRTVQAVVELKNRPLMWHKARKVTLQSGQTDVKIDFSLPITACNLMI EYADFYETVSGSSESLQCPRCSAVVPANPGVCGNCGENVFQCHKCRAINYDEKDPFLCHS CGFCKYAKFDYSIYGRACCAVDPIESAEDRTKTVQTIHTSLEKADRSYKSLQNNKQILEL LVQKVSEHKLDRTLDETIVGASVIGGAGGTSQVNKVIQLLAQKYCVESKTTFEDLSKIIQ KVQACRKELVAYDRSQMDAPPPGAGSMSTSFASSTGISSRTGTVALNKCYGCALASTEQC LTLLRAMASNMACRVGLCSQGLVQELAVNNLRRGTHQLQDEVRHLLCLLTRDLPDATGAL CQLLQDRVKMALSGTVPLSTLDSAVRHEMALLEAMTSQDDSCWETKLRTVIELFLQASRD ARGPATAVIHPCLRIVQSLICPPPILATTISTGSKQHGKEPIATTLQDLCTVQPVEGITV SYEKWIAGDANHSFAAWKARMPPAANASAAVGSNRRIMGESSSVSMNTAAVTPPPIGTGF RSALEHRRATIRNAYLVEKYAKRWRQKVLVKGVSSIPVELQAAWLQPILFNTNSRLGRQL ACALITSLSRTNERKRELLDLLTSFLRYVGDSGEASAEFLALYRMLADETPWRQYLALKG VLTLLVQLVTVEIEKIHCLEETTLSTDLAQGYALRQLVELMALFLENPQIRKAYKGKLLG PVLQGYLDLRKLIVQRTRLIDDAQEKLLEMLEEMTTGTEEETAAFMAVCIDTVRRTPTTD VKTPVFMFERLCSIIHPEENDVGEFFLTLEKDPQQEDYLQGRMLGNPYPSHEAGLGPLMR DVKNKICIDCELVALLDDDNGMELLVHNKIISLDLPVKEVYKKIWLQEGGERDSMRIVYR MRGLLGDATEEFIETLNAKSQEEVDNEQLYRMANVLADCGGLKVMLERIGSLQNVSKSRT LLQVLLKLFLLSVKVSRCQEVLCQPELGAINTLLKVLQLCLQSSESDTQQSAVTEQLLEI METILSKAASDTLDTFLQFSLTFGGPEYVQALLSCTNCSNVRCNPSVLRHLIRVLAALVY GNDIKMALLCEHFRSVLDFDRFDAERSAEEEFKMELFCVLTTGIEHNSIGGTLKDYIMSL EIVEKALNYIKSHAPCVKPTLLRTDSDELKEFISRASLKYILRFLTGLATKHEATQLAVA QDIIPIIHRLEQVSSDEHVGSLAENLLEALCTEPATAKRVQEVRDFTRAEKKRLAMATRE KQLDALGMRTNEKGQVTAKGSILSQIEKLREETGLACFICREGYACQPNKVLGIYTFTKR ANVEEFEMKQKKTIGYTTVTHFNVVHVDCHMNAIRLARSRDEWESASLQNANTRCNGLLP LWGPDVSESSFSSSMARHNNYMQECTQRCEITFASSMHDLKLLVWRFAQEKSFHEDAGGG GPQSNMHLVAYLLFYGLYTLLSSRSYSREEMILSGFIGHKPSERWLECAYEAEGPLYLLT MSLALHTPDLWSRHKQVHLQRLIAIAQARHVSPNTVCKFLAPADKRPKDYTIYKPYLMFW GLIDLIYRNFFRTVGTPKDEDWPISLFNYIRRNDESLLKTADTTLQTFTEEYLPCASFGE FCDVAGLLGDIENPDAWMEELLQALPSPGGSSAAAGSSAAGPSGGTGSGATAGSSNTD NT seq 16557 nt NT seq  +upstreamnt  +downstreamnt atggctgctgcccattccggaggtgttgagtgggctgcaattttaaagccttttctttcg tcatcaagtgaaaatatcagcaaaaccgatgtgttaaacttgatcaaaaccataatacaa aatgaaaatgaaatcctcgagcacgatgccgcatacaagcagtttttcgacaatttcgtt gtgctggctgcagagaacatcactagccaggtcacctcattgtcgcaaacacaacttcaa cagtttacggaagctgcttcaatattaattcgttacataattctacatttggatacgact gcaccatgcaaacccagcattctgttgatggccctaaagattctttgcgaagggaaaagg gcgaacgaaaatcagccgaatgctaccagctcggcttcgtcaatcatttcagtgtctggg atgaagtacttaaagtatcctgagattccgggaaataaaccggcttcggtcggagcccca agtagcagcggcagtggtggctcggccgctggcacaagcgataaggaaagtcccaaaacg gaaatgaaacgttcgcgatcggatttgtcgacggtgatcttacaacagctaacgactcca ttgtgcagctgggctgtaacttttgctgcactcagtgaagaacaaattgactgcacggat ttgttcgtgaagcaaaatctacaatgcatgaatgcaatcaatgctggagaatcgttactc aaatggtgttcgacggcgttaggtacgttggccaagtatcgcttcaagtacgaagagtac accatgctgggccgtccgctttacctaccggttacaaatactgaggcgaatgctatcaaa aacattttcaatttgatggagtccgacataacaaatttgcaattagcgatctctctacct cttctggagccgctaacccccaagaaaatctcgctcctgtcgcagtgtgccatgtctgca ctttactgttgcgtacttacatccaccgctgtgagtgttattactatggcatctgctgga tcgcagaaaaccgcttcctctggtcaattacagcaagcgcaaggacaaacaggaggaacg caaacacaaaaggaaagcgaagaggaagaagacttcgcccgaacgattgtggacaaagga ttggaaatttttacgaaaattggcaacatgctcaaaacgtccacacgtacccacatttac cagaaccacatgtgtatgggtgcatggttattgatatctggcatccaaggtacgatgggt gcctccggaaataccagcggactgcaacagatggtgcccatttcagcgaaaacatcggaa gaaagtttgaagggacgcagtcctctaaaaacgcttgatgtaccgcaaatggcatcagcg caaccgtcaccagcattgcgcgtgaatctgttcaaagttcagcaaggatttggcgtgttg aatgcggctattgctcgtcacagtatcaccttgatgacggagctgatcgatgatctgaag atagactcccgtactgatgatgatgaatacagtagcatcgaatcggccggatttgatatt ctgggacagtacacgtcgattcagcgtgtggtacgtgtgcttaacagtgccacgctgcaa cagctgctcacattccttgctacagtatcctatcgcaaagcatgtacccttcgcagaatt aacaccaaaaacacaaacgatggagaaccgatgagctacagtgattcgacgacatacttt aatgatacgttctcctgttcggaggagagcgaaccggaagaagaggacagcgatagctac cttggactttggttcaaggaaacgctttctccggatatgaatgaggagatgaccgaatcg caagaacaggaaaataaggatgataaaggtcgtcacggtagcaatcttgtgccggctaag gatgaacctcacgaatatcttaatctggcctccttaattttcaacttcttcgatgtttcg ctcggtggaagccacatctacctgagtcgttacgtgaagacaggtctcagcgaacaacag atggtactgttagccaacatcttgcgcgatcttgatcgggattcggctcgcggcgaaact gatatacccggttgcatgcagtggcaaaacgccatggtgaagttttctggggccgttgga cgttatttgcacaatctaatatcaaactcgctgctgaatgaatcgctgcagtctgccctg ctgctgcatttgggagtatcaccatggacacaggatgcaaacatttggccactccaggta tattcacgaacacttgctgtgctggttcaaattcttttgctgaaaccgtcacaggaaaaa gaagcagcgtgtctgtctgtgtggcatcgtcttgtgaacacgatcgtggaaggcatttgt tccacccaaaccatccctaatgaatcagagatagaagatctcaacgtggagcatgctcag ctgctgctgtttctgttccattcactcaacctgatgcaaaagaaatctatacttctgctt acggcagggggagtcatacgctgctcggaggtatgtcgcagtgtcacacccgataaaccg ttgagagatcaccagatcatgctgctgtcccggttgctgctattcctggagtatctgatg aaacacctgtacaatccaccaaacgttttactggagcaagtgcgctggaacttgttcagt gtgtttacgctggatagtgaacaaaaattggctgatttggtaaactacaaaacgaaaatg atgtcattctgtcgaaaggacatagaagacaagcaccgtaagctggcaaacgagtttagt gttggtggcgtgaaacccaagttctactcgctgactacagtcgaatcgaaggtgcagcaa gagtttaagctcgacggtttggcctggaattttattctttgcacccccgacaagctaaag tacccgtggcttattgatgctttaattgatatcctgggcataacggacatgtgccttgca cgtatcccttttcaaactttgtgcgctgtgcattattgtttcagtcttagctggaagtta ttgcttggtttgccaccgtctacgcagcacgtggaagcactgatgcaggaaaagagtcca aatctacattctttgttgtggtctattcgttgcctgcatccaataacccattcgcattat ctaattgtgaacagtctcgttaaacagggtatgtatactcagtcagcggaggcaatgtgg atccggctaacggaatatgtttccgatgtgaagtacagtttgaaaatgaccttgctcgga ctggaatcctttgcgaagagctttacgccagatcaaccaagattgtcaaagattatactg ctagacagtcttatgtcgcatctgtttgctgtttgttgggcagaaaaagagggtgttaat gtgaaagctgccaaaaccaatagtaatacggtcgcatcatctgcaacatcatctgccaca gctagtaatacctcaacggcaaacgctggctcatcgccggtggtcaccaacgaaagtaat gctagcggagcaagttctacgacagtatcgggagctgcaaacattgttgcgtctggccca tcagctagtacatcttcatccgatgggtcgccgtgtgttatctcggcagaagtctctcgg gccgatttgacaaagaacataatgcacgctttactggacgtattggaaatagttcgcgaa tcaacctacaaaactatgttccagaatttgagtggccaaataccgtcctgtttgattgaa ccactgattgccattgcgggcacaaagaattcgttttgttcggaacttgctcaacagctg gttagttgtatcactggtcacgataaagatgtaatagctgttgaatggcgcaagagtttg agtacgttgaccgaagaaaatttcatcagtggatcatttccggtggaattgcacaccctg acggtgatcgaagcacacctgacggaggtctccaaacatctgtcgtactccatactgttg tctctgaagaacgctctcaaatcggcggtcaatctcatatactacatgcttccgaactat gacgatatcaagttggacgaacgtttgaaggaaatcctgatcccaatggtgttcgatttg cgtgcagaatacttgcacgggccgatcaacaaatgcttggagtcgttactgggtggagat agcaattgcgaagcatatcagctggccgcgttctcaaacatcatcaagcacagctaccaa tttcttatcgaatataccgacctgtgtgctacaggctgtgccacgaatatcgatgaatcg gtactctgcaacattctcaagtattgggaattgatgttagaaaaatcgaacggattgcgg gcaatgcgcaactttttctacgagtcaaagtccggtaatctggtgcaaatattgctatcc ttcactggcaccaatatttcgcaggcttactccacacgcgtacttcagttctttgagaag ctgtttcaagccgcggaaaaacttgatgcgcctttcgatgaggaggagctatgttcatgt atcgcagagctggcagttaccgatagtacacgtttgaagagttggttaagtcatattcta cttggtcctggaggaatcagtgtaacgccaaacgcatccaataattcgagcaatgtacca actccgacaaatatggcaacagtatcggcaattccgagcattactgaccaactggtgggg tcagcaacagcagcaggtggcgtagaacccggtttatctgaaagcaacactacagctgca aatgcacccaccactaccgagggtgagcagcaggacgccatggatatcgattatgaatgc atgactaagggcagtggatggcaggcagcagcaacgagctgtggaaaggtcgctattgaa gatgcatcaggcgaaacattggaacgcaacggcaagctgctccagtcacttgttaaatac atagttgcggagaatcgtatttcctcgtcagtatcggaagccctatttcaagccctaatt caaatcggtcacaaccttctttcgccgacgcaggaagcaatagagttttctgacctcttg caggtgatgatcacccttgcggatgctggtaaaggccgtggtcatggtatactgttttcc gctgccatcgattggttggatgtatgccgggcgcaagttttggatgcaggaaaagccgga tcaagtggatggagggcagcaattcagctcgataatgtgaccgctattctgaagtacatg agcgatcttctgatgggactgggcgctaagggcagccgtgtactgaatccaccttgggac gaagagtcgctgctggatgcggatgacattttggaagagcttggaggggaagaggaagat agcacagtcgacgactccgatgaggacagtctcggcaataagctctgtaccttctctatt acacaaaaggattttatgaaccagcattggtactattgtcacacgtgcaaaatggtggac ggtgtgggcgtatgttcggtgtgtgcaagagtttgtcacaaaaatcatgacatcagttat gcaaagtacggtaatttcttttgcgattgtggcgctaaagaagatggttcgtgccaagcg ctaagccgacgcagtaattctgggcatacagaggattcaatattgggtccatcatcggct gcttccatcttgccacgttccaatgatgctgaaagcgttttgctagcaagcagcttaatg agacgacgacatcctaccagtccttcgcatgaaggccccagttcaagccgtgcagcacaa ggacaaacttcggagaaagagcaacaattggcaaaaatcattgaaacttcgcgtgaagca ttgaacaatcccagtcaatggaaatccgtgattcgttgcattcttgtgttcttcaattca ctaatgcctacagtcaaagagcattgtgcaagatattctcccgtgggctgttactggcgg gctaagaatgcactggagcgtctgcatcgtccggagaaatcgtatgtattgagcgacgac atcatgattgctacgcttggttctcaggaaggtgcgttcgaaaatgtacgcatgaactat tctggtgaacaaggtcaaacaattaaacagctgctctcaacgtatctcgtgcgtcgggtg gcattgtgttgcctggcttctcctcatggtaagcgccagcaattagccatctcacacgag aaaggaaaagttacgattctacaattatcggccctattgaagcaagcagatgcggcaaaa cgcaagcttacgcttaccagactcgcatcggctccagtgccgtgtaccgtactttcgctc gcatcaaacccggctaacgaagattttctagctgtgtgtggtctgaaggagtgtcacata cttacattcaccagcacgggtactgcaaacgatcacatcgtattaactcctcagcttgac acaggaaatttcattaagcgagccatctggctaccatcttcgcagaccaaattagccctt gtcacggctgattttgtaaaaatctacgatttggctgatgacagctatagcccgcagtac tacttcctggtgcctagcggcaagattcgcgattgcacatttgtttacgatcaagagggt acgtactacatgctgataatgtcttcattgggctacatctatacccaaccgcttagcgat gaaagcctggcaaagcatggtcctttctacgtaacaagtacgctagaacttgaccatcca ctgatcacagacgacaacggacagattctggcaggaggtgtatcgatatactattctcac gtcctgcagctgttgttcttcagttatgccgcgggtcgcaactttatggctccgctcacg aacgttaatgatggtgtcaagtgtgtcatcaacctagtatgcaatcccagctccaaattg ttatcgaaatcaacaacacaaccactctgtcagtggaccgaaattcccggtcatccgggt ttggtatgcgcaatgatgcagagccttaacaatcctgtcatcttcatgatcaaaccagac ggatatatggcccaggaaatcaaggcacagaatgcaaaggcaaaaataatggatatggtc gccatccgacacagcgtgtctggtgtagaaaaaacaacactgattttgctttgcgaagat ggcagtttgaggatttatgctgctcatccagagaataccggctactggttgtctccagaa gtgcaaccaatcggacatcagcaatcgttcggctggtttggatcaggcggaagtatgtat ggcaaatctgcacgaaaatcgaaaaagatgggaaaacaatctggccacggggtgaacgct actgcgtcaaccaccgggaagggggttgcggggtccgctcctaatttcccgattgatttc ttcgaacattgcacgctgatgaatgaagtagaatatggtggaaacgatttgctgcaaatc tacaatacacagcacctgaaacatcgtttaaactctaccggactgtacgtgacatcaact aaagccaacggattcatgctggaagtctcaaataatgatccgaatatggtcataacaggt gttcgcatacaaattggatcacaggacgttactaaagcaccgcagcgtgtaaccatattg ggtcgatcagtaaccaccgtagctacaagagcccggtggtttgatataccattaacaaga gaggaaagcctgcaaagtgacaagaagcttaccattcactttggaccttcggtggatgcc gaacaaatcacgatacttgacagtatcaagatttacggaaaaactaaagatgtattcggt tggccggaggaaacggaagatgcggctggaggacaattaacaaatggtagttccggaaac aatgggcagacggcggtagcaaatggaaatggtggcaatgagggcacttctaacgatgaa aatgatgtaggagcgatgtatatgacttcgttggatcgtatgctttccagtatgctgcac gtgctagacagtggtatatccttgctaggtggaccaaattgtgatgacaactaccgccaa acagctatcgatgtagccacaaatctaatcctcttcccgaccgtaaatgtcgtacagcag gacgcacgcaacgtactcatgacatgccacgccaacaaggcggcttaccacacgtacaaa gataaggaaatattgaacgatatacatcggcagttgaaaaaaatgtacgaatcaaccgag agtggagatattgatcctgaagccttttatcgagtagtgttgatgatgcgcagtatcgca attcaaagaccgcaagctatggcaaagatatgcgccgaacaacagatggacattctttca ctcatgatgatcctcatgaaagaactgtaccgtataacaccagcctacgaagaaccgatc gcgatcgttaaacgcggactgtgccatgtggaagcagtcatttactcgctggtggaaatc atttacgcattcgctttggccgacagcgaacaggtggagaaaatggcgaaacttttcgtt cggctattgcttgattcggctccaatcataagccatagtgcgaaactagcgatgattcgt ttattgcggccaaaagtcaagcgccgaaaggtggtgctaatcgaaagtcctccggtctgt tccacgcctacaccctccacatcaggggttgcaacatccactgcgggaccgtcaacatcg accatatcaatcggatcggcctcatccggacctgctggaccttctacttcatcgggaagc attgctacggctaacgatgaatttgtaacagcagctgctgcggccgccgtcggtggaatg caggaggttgacgcaatagaatcgctgggattagaaccgagtgctggaaaccaggccctt gcttcgcttgaggctctattgggtgttggttttccccatttgctcgagacacatgatgcg gacgatgatactataatggagatagcgattgcacttagcctgcaagataatgaagctgat ctgcaacttttgcaacagagcatcgctaattatcaaggaagaaataggaacccagctgca caaagcctggctgcagccattgccggcggttcatcatttaacgtcgaatccaacgcgtcg ggaggtggctcggatgatgatgaaatttccaacgttgccaccgaaggatcgactctccga acatctcctgcaggtgaacatgctggtagtggtagtggtggatccgagagtggttgtagt ggtgtcgaaagtatcggtggtacttcaggacgcagttcaacgtacgaagagcaaccgaat ccttcgccaccgcgcacttctgtagtcgaccaaatgagctcgcaatcggtcggtactaca gcaacagcagcacacccatctgctgcagaagccgaagcgtccgactctaacggagaaact gcaaacaaattgcacgtgctgcgatactccatcttgaatcaactggtggacaacttttcc gccctagacacagtaaatggcgcacagtgcataccgtttatgcaggttatcctaatgctt acctctgatctggatggcacccaggaaccggatcagcaagctttgaaccgtttactgcaa gcattaatcgaccgactagaaattccaactacgaaaatttaccagatggctgaaagaacg gcaagaacagaagtacagcttctcattctacgcctgattggtgtgttaatgggaaaagtg aagtcaaaatcatcatcgtcatcctcctctgccaacactacggcggccactagctcgagc gcggataggtcgggtgtgaaccaacccttagggggggataacgcatcatttttggctcaa agcactgctaacgcgctgatgaaaaacaatgctatcccgtattgtctcctgataatggaa tcctttttgccccattggaaaacctccggtgcatcatcagtcgacgagttggcttcaccg gcaacaagtgcaaccaccgctaatgcttcagcgaatgcagcttcctccagtggtggcgga gtgtctaatgcgacgtcaaataataacggtccggtaataacagcaccgggaggcactcca tcgaacgttctactgaaaccgacacaatatggaataatacccgatacgcaaccgtttttt gcgagacccatcccgaaagggtcaggtgatgtgtttgagttgtactcacaggtgcttacc gagatggcggttcgattgccgtatcaaatactgaaactttcctcgggccatccgtcatct caagagtggaaccattcgttgtgcgagtacatgaccgctattctctgtgagtatatgatg tacatgcagtcaccagttttacgtcgacaagttcgcaaactgttgttgtacatctgcggc agcaaggaaaagtatcggcagttgcgcgatctccactcgcttgatacgcatatgaaggca gtaaagaaatgctgtgagcttaattgtgctcaagccgcatcatcttcatcactaacgaat ggtggccattcgagcattctcggttacgactcgttagtcgaactgacggagcatttccgc gcgtgtcaggagattgcatctattcgcaccggaaactggcaaaagttctgcgtccgtaat gctgacatactatcttcactgttgaatatcagtacctaccagcttgaagaaggtgtttcg acgattattttacaacttctgcaatcggctatatgctgcaacacttcatcacagatgcaa ccatcaaaagcatcatcatcgtctggcgtgacggtggatccacaattgaaagtgtcggtc attgtaaaggatcggaaagatcgcgacaaatcggaagaatcggacacgatttcagcgcag tcagaatctaaattcgatgcgggacaatgtgtagcgctagtggctcaaattttcaatcag atcagtccagctagtatgagcaaattcatccgtagcttcctgctcgaaacgaactcaacg tcgattcgctggcaagctcacagcctcgtgtatgcattctacgacaactgcagcgacatc aataaggaaacgctgctccagtgtctctggagtttgtggccattgctaccggcttacgga aagcgcactgcgcagtttgtcgatttacttggtttcctcacgctcaacacacgttcgctg atagacaagctaccggactacactgcacaggcggtatcagtgctgaggcagcagaacgag ctgctctccaaacacccgaatgcccctatctacaccgctttggggcaagtgttggaactc gaaggtttctatctcgaatcggaaccatgtcttgtttgcaataatccggaggttccattt tctaatatcaaactgtcaaccataaaggtggactccaagtttaccaccactacaacgatc gtgaagctcgtgcaaagtcatacgatctcgaagatagtgctacgcatcgctgatctaaag cgggccaaaatggtgcgtacaatcaatatctactacaacaatcgtactgtgcaggcagtg gtggagctgaagaatcgcccactgatgtggcacaaagctcgcaaggtgacgctacagtct ggacaaacggacgtgaaaatcgacttctcgctcccaataacagcgtgcaatttgatgatc gagtacgctgatttttatgaaacagtaagtggatccagcgaaagtctgcagtgtccccgt tgcagtgcggtggtaccggcgaatccaggcgtgtgtggtaactgcggcgaaaatgtgttc cagtgtcacaaatgtcgcgccatcaactacgatgagaaagatccgttcctgtgtcattcg tgcggcttctgcaaatatgcgaaatttgattacagtatctatggtcgagcgtgttgcgcg gtggatccgatcgaatcggccgaggatcggacaaaaacggtgcaaacaatccacacatcg ctggaaaaagcggaccgttcctacaaatcgctgcaaaacaataagcaaattttggagctg cttgttcagaaagtgtccgaacataagctcgatcgtacactcgatgaaactatcgtggga gcttcggttatcggtggagcaggaggaacttcacaggttaacaaagtaatacagctgctg gcccaaaagtactgtgtggaatccaaaaccacctttgaagacctgagcaagatcatccaa aaagtgcaggcatgtaggaaggagttggtagcatacgatcgaagccaaatggatgcacct ccacctggggctggttctatgtcaacgagctttgcctccagcactggaatatcgtccagg acagggacggttgcgttgaataagtgctacggttgtgccctagcatccaccgaacaatgt ctcacgttgttacgggctatggcgtctaatatggcttgcagagttggtttgtgcagtcaa ggtttggtgcaagagctggcagtgaataatttacgccgtggaacacatcagctgcaggac gaggtgcgtcatttgctgtgtttattaacacgtgaccttcccgatgcaacaggagcgctg tgtcaattgttgcaagatcgagttaagatggcactttccggtactgttccgctgtcaacg ttagattcggctgttcggcacgaaatggcactactggaggcgatgacaagccaggacgat agctgctgggaaacgaagttgcgcactgttatcgaactgttcctacaggcctcacgtgat gcacgaggtccagcgactgctgtcattcatccgtgtttgcgaattgtgcaatcactcatc tgtccgccgccgatacttgcaacaacgatttccactggaagcaagcagcacggtaaagaa ccaattgcaaccacgttgcaagatttgtgcacagtacagccagtcgaagggattactgtc agttacgaaaagtggatagcaggagacgcaaatcattcgtttgctgcctggaaagctcga atgcctccagcagctaatgcgagcgctgcagtgggctccaatcgtcgtataatgggcgaa agttcatcggtttctatgaacactgcggcagtaactccacctccaatcggaactggattc cgatcagcgctggaacatcggcgagctactatacgaaatgcgtatctggtggaaaagtac gcaaaacgatggcggcaaaaggttttggttaaaggagtttcatcgattcccgtggagcta caagcggcttggctgcaacctatcctctttaataccaattcgcgtctcggacggcagtta gcctgtgctctcattacatcgcttagtcgcacaaacgaacgcaagcgagaactccttgat ctgcttactagttttctacgctacgtcggtgatagtggagaagcgagtgctgaatttttg gctctttaccgtatgctagcggatgaaacgccctggcgacaatatcttgcgctgaagggt gtcctaacactgctcgttcaactggtgactgtggaaattgagaagatccattgcctcgaa gaaacgacgctttcaaccgatctagctcaaggatatgcattacggcagttggtggagctt atggcgcttttcttagaaaatccgcaaattcggaaagcgtataagggcaaactgttgggg ccggtgcttcagggctatctcgaccttcgcaagctgattgtacaacgcactcgtttaatc gatgatgcgcaagagaagctgctagaaatgctggaggaaatgactacggggacggaagaa gaaacggccgcatttatggcggtttgcattgacacggtgcggcgtacaccaaccacggac gtaaaaacaccggtcttcatgttcgaacgtttgtgctccataatccatccagaagaaaac gatgtgggtgagtttttcctcacactagagaaagatccccagcaagaggattacctgcag ggccgtatgctgggaaatccatatccttcccatgaggcaggtctggggccgctgatgcgt gatgttaaaaacaaaatctgtatcgactgcgagctggtggctttgctggacgacgacaat ggtatggagttgttggttcacaacaaaatcataagcctagatctgccggtaaaggaagtg tacaaaaaaatatggcttcaagaaggaggagaacgagacagtatgcgaatcgtctatcga atgcgaggtttgcttggtgatgcgaccgaagagtttatagagacgctaaatgccaagagc caagaggaggttgacaacgaacaattgtaccggatggcgaacgtgttggcggactgtgga gggctgaaggtgatgttagaacgcatcggaagcttacagaacgtgtcgaaatcacgcacc ttgctgcaggttctgttgaaattgttcctgctaagcgtaaaggtgtctcgttgccaggag gtactctgccaaccggaactgggggccataaacacgctcttgaaggtgttgcaattgtgt ctgcaaagcagtgagagcgatacgcaacagtctgccgtaacggagcaattgttggagatc atggaaacgattttgtccaaggctgcttccgacaccttggacacgtttttgcaattttca cttacgttcggaggcccggagtacgtgcaagcactactatcgtgcaccaattgctcaaac gttcggtgcaatccctcagtactgcgacacctgatccgtgtgcttgcggctctagtgtac ggaaatgacatcaagatggcgctcctgtgtgaacatttccgttccgtgctcgatttcgat cgattcgatgcggaacgtagtgccgaggaagagttcaagatggagctgttctgcgtactg accaccggtatcgagcataattccatcggcgggacgctgaaggactacatcatgagcttg gaaattgtggagaaagcactcaactacatcaagtcacatgcaccgtgtgtgaaaccgacg ctgctccgcaccgactcggacgagttgaaggaattcatatcgcgagcctcactcaagtac atcctccgtttccttaccggtctagcgacaaagcacgaagcgacgcagctagcagttgcg caggatataattccgatcatccatcgtctggaacaagtgtcaagcgacgaacacgtcgga tcgcttgctgagaatctgctggaggcactgtgcactgaaccggcgacggcgaagcgagtc caagaggtgcgtgattttacgcgtgctgagaaaaagcggcttgcaatggcgacccgggag aaacagctggacgcactcggaatgcgtacgaacgaaaagggacaggttacagcgaaggga tcaatcctctcgcagattgagaaactgcgcgaagaaacgggcctggcgtgtttcatatgc cgcgaaggatacgcctgccaaccgaacaaggtgctcggcatctatacctttaccaagcgt gccaacgtggaggagtttgagatgaagcaaaagaagacgatcggttacactacggtaaca catttcaacgtcgtgcatgtggactgtcacatgaacgcgatcagattggcccgatcgcgt gacgagtgggaaagtgcatcgctacagaatgcaaacacacgctgcaatggattgcttcct ttgtgggggccagatgtgagcgaatcttcattctcgtcgtcgatggcacgccacaacaac tacatgcaggaatgcacgcaacgatgtgaaatcacctttgctagctcgatgcacgacctg aagctgctagtgtggcgttttgcacaggaaaaaagcttccacgaggatgcgggtggtggt ggaccacagtcgaacatgcacctggtagcatatctgctcttctatggactgtacacgttg ctctcgtctcgttcttactcgcgagaagagatgatactcagtggtttcattggccacaaa ccctcggaacgttggttggagtgtgcgtatgaagcggaaggtccactgtatctgctaacc atgtcattggctttgcatacgcccgacttgtggtcacgccataaacaggtgcatctgcag cgactgattgcgatcgctcaggctcgtcacgttagcccaaacacggtttgcaaatttttg gcaccagccgacaagcgcccaaaggattacaccatctataagccgtatctgatgttctgg ggactgatcgatttgatctatcgcaactttttccgcaccgttgggacgccgaaggatgaa gactggccgatctcactatttaactacattcgccgaaacgatgagtcgttgcttaagacg gctgacactacgttgcaaacattcaccgaagaatatctaccgtgtgcttcgtttggtgaa ttttgcgatgtggcaggactgcttggagacatcgagaatcctgatgcttggatggaagag ctactgcaagcgttaccttcaccgggcggatcatctgcagctgccggctcgagtgctgca ggcccaagtggcggaacgggttccggagcgactgcaggatccagtaatacggattag

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