Actinoplanes missouriensis: AMIS_11300
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Entry
AMIS_11300 CDS
T01795
Name
(GenBank) putative folylpolyglutamate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
ams
Actinoplanes missouriensis
Pathway
ams00790
Folate biosynthesis
ams01100
Metabolic pathways
ams01240
Biosynthesis of cofactors
Module
ams_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
ams00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
AMIS_11300
Enzymes [BR:
ams01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
AMIS_11300
6.3.2.17 tetrahydrofolate synthase
AMIS_11300
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Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
BAL86350
UniProt:
I0H013
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Position
1205986..1207314
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AA seq
442 aa
AA seq
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MSAEYSEVEAALDKRGFTRMVFDMQKIRDLMDVLGSPQRAYPAIHLTGTNGKTSTARMID
ALLRAHGLHTGRYTSPHLETVRERISLDGDPVSEEKLVTTYQEIVPLAELIDARNAEPLT
YFDMTTAMAYAAFADAPVDIAVVEVGLGGEEDATNVIEAGVCVLTPIGLDHTEWLGDTIE
DIAWHKVGIIHSGATVITALQDEEAMRPILERCADMGATLAREGSEFGVINRAQAVGGQV
LTLQGLGGVYDEIFLPLFGAHQAQNAALALAAVEAFLGAGPNKQLEADLVREGFAQVDSP
GRLERVRSAPTILLDGAHNPHGMAATVTALEEEFTFRHLVAVVAVLGDKDVSGLLDLLEP
VAARIVVTQNSSPRSMPVDELAQLATDIFGEDRVSVAATMPDAIEEAVVLAEEDSSGELS
GVGVLITGSVVTVADARKLLKR
NT seq
1329 nt
NT seq
+upstream
nt +downstream
nt
atgagcgccgaatattcagaggtggaggccgcgctggacaagcgcggcttcacccgcatg
gtcttcgacatgcagaagatccgggacctgatggacgtgctgggcagcccgcagcgggcg
tacccggcgatccacctgaccggcaccaacggcaagaccagcacggcgcggatgatcgac
gcgctgctgcgggcgcacgggttgcacaccgggcgctacaccagcccgcacctggagacg
gtccgcgaacggatcagcctcgacggggatccggtctccgaggagaagctggtcaccacg
taccaggagatcgtgccgctcgccgagctgatcgatgcgcgcaacgccgagccgctgacc
tatttcgacatgacgacggcgatggcgtacgcggcgttcgcggacgccccggtggacatc
gcggtggtcgaggtcggtctcggcggcgaggaggacgccacgaacgtcatcgaggccggc
gtctgcgtgctcaccccgatcggactggaccacaccgagtggctcggcgacacgatcgag
gacatcgcctggcacaaggtcggcatcatccactccggcgccacggtgatcaccgcgctg
caggacgaggaggccatgcggccgatcctcgaacggtgcgcggacatgggtgccacgctc
gcccgggaggggagcgagttcggcgtgatcaaccgggcgcaggcggtcggcgggcaggtg
ctcaccctgcaggggctcggcggcgtctacgacgagatcttcctgccgctcttcggcgcg
caccaggcgcagaacgcggcactggcgctcgccgcggtcgaggcgttcctcggcgccggc
ccgaacaagcagctcgaggccgacctggtccgggagggcttcgcgcaggtcgactcgccg
ggacggctggaacgcgtacgcagcgctccgacgatcctgctcgacggcgcgcacaacccg
cacggcatggccgccaccgtcaccgcgctggaggaggagttcaccttccgccacctggtc
gcggtggtcgccgtcctcggcgacaaggacgtgtccgggctgctcgacctgctggagccg
gtggcggcccggatcgtcgtcacccagaacagctcgccgcgctcgatgccggtggacgag
ctggcccagctcgcgaccgacatcttcggtgaggaccgggtgagcgtcgccgcgaccatg
ccggacgccatcgaggaggcggttgtgctcgccgaggaggactcctccggcgagctcagc
ggtgtcggggtgctgatcaccggctcggtggtcacggtggcggacgcccggaagctgctg
aagcgatga
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