Actinoplanes missouriensis: AMIS_15200
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Entry
AMIS_15200 CDS
T01795
Name
(GenBank) putative UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
ams
Actinoplanes missouriensis
Pathway
ams00300
Lysine biosynthesis
ams00550
Peptidoglycan biosynthesis
ams01100
Metabolic pathways
ams01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
ams00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
AMIS_15200
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
AMIS_15200
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
AMIS_15200
Enzymes [BR:
ams01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
AMIS_15200
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
BAL86740
UniProt:
I0H153
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All DBs
Position
1635481..1636857
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AA seq
458 aa
AA seq
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MIPLTLGEIASITGGTLVNAAPDVTVTGGVEYDSRKVGPGGLFVAFDGEKVDGHSYAGGV
IAGGAAGVLATKDVGVPSVIVEDQLAALAALAAHVVRNLDKLVVVGLTGSSGKTTTKDYI
GQLLSRLGPTVAPAGSLNNELGFPYTVLQATPETRFLVLEMGARGIGHIRYLTEIARPSI
GVVLNVGAAHIGEFGSIEGTALAKGELVEALPVDGVAVLNADDPLVSAMASRTSARVVLT
GSSAADVQAAEVKLDASGRASYLLKWGGRSGHVALGVVGQHQVANTLAAAAVALAAGMDF
DELTTALGEVGIVSGRRMDVFQNPAGVTVIDDSYNANPSSTAAALRALASMGEGRRTTAV
LGYMAELGEHEISGHAEVGRLAAELNIDRLIVVAENARPILDGAAALADKHLAADQAEAI
AILKQDLRADDVVLVKGSRYRTWDVADWLRRPEEVQPT
NT seq
1377 nt
NT seq
+upstream
nt +downstream
nt
atgatccctctgactctgggcgagatcgcctcgatcaccggtgggacgcttgtcaacgcc
gcaccggacgtcacggtgaccggcggggtggagtacgactcccgcaaggtgggaccgggc
gggctcttcgtcgcgttcgacggggagaaggtcgacgggcactcgtacgccggcggtgtg
atcgccggcggcgcggcgggcgtgctcgccaccaaggacgtcggcgtgccctcggtgatc
gtcgaggaccagctggcggcgctggcggccctggccgcccacgtcgtgcggaacctcgac
aagctggtcgtcgtcgggctcaccggctcgtccggcaagacgacgacgaaggactacatc
gggcagctgctgtcgcggctcggccccacggtggccccggccggctcgctcaacaacgag
ctcggcttcccctacacggtcctgcaggccacgccggagacccggttcctggtcctggag
atgggcgcccggggcatcgggcacatccgctacctgaccgagatcgcccgtccgagcatc
ggtgtcgtgctcaacgtgggcgcggcgcacatcggcgagttcggctcgatcgagggcacc
gcgctcgccaagggcgagctggtcgaggcgctgccggtcgacggggtcgcggtgctcaac
gccgacgacccgctggtgtccgcgatggcgtcccggacgtccgcgcgggtcgtgctcacc
gggtcgtccgccgccgacgtgcaggcggccgaggtgaagctggacgcgagcgggcgggcc
tcgtacctgttgaagtggggtgggaggtccggccacgtcgcgctcggcgtcgtcgggcag
caccaggtcgccaacaccctcgccgccgccgccgtggccctcgccgccggcatggacttc
gacgagctcaccaccgcgctcggcgaggtcggcatcgtctccggccggcgcatggacgtc
ttccagaacccggccggcgtgacggtgatcgacgactcgtacaacgccaacccgtcctcc
acggcggcggcgctgcgcgcgctggcgtcgatgggtgagggccggcgcaccacggcggtc
ctcggttacatggccgagctgggcgagcacgagatctccgggcacgccgaggtcggccgg
ctcgccgccgagctgaacatcgaccgcctgatcgtggtggccgagaacgcccgccccatc
ctggacggcgccgccgcgctggcggacaagcacctcgccgccgaccaggccgaagccatc
gccattctgaagcaggacctgcgcgccgacgacgtcgtgctggtcaagggttcccggtac
cgcacatgggacgtcgccgactggctgcgccgtcccgaggaggttcagcccacgtga
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