Actinoplanes missouriensis: AMIS_40250
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Entry
AMIS_40250 CDS
T01795
Name
(GenBank) putative 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
ams
Actinoplanes missouriensis
Pathway
ams00290
Valine, leucine and isoleucine biosynthesis
ams00620
Pyruvate metabolism
ams01100
Metabolic pathways
ams01110
Biosynthesis of secondary metabolites
ams01210
2-Oxocarboxylic acid metabolism
ams01230
Biosynthesis of amino acids
Module
ams_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
ams00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
AMIS_40250
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
AMIS_40250
Enzymes [BR:
ams01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
AMIS_40250
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HMGL-like
IPMS_D2
LeuA_dimer
Motif
Other DBs
NCBI-ProteinID:
BAL89245
UniProt:
I0H8A8
LinkDB
All DBs
Position
complement(4252416..4254035)
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AA seq
539 aa
AA seq
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MPSHKYHDVYARVAVPLKDRMWPSRRLTEAPLWVPVDLRDGNQALAEPMDPARKRRFFEL
MVAMGYKEIEVGYPSASRTDHDFVRLIADERIAPPDVTVVVFTPARPELIEQTVASIAGI
PNDVVIHMYAATAPLWRSVVLGHDRASLKELILEGGRHILKLAGHLPNVRFQFSPEVFNL
TEPEYALEVCDAMTELWEASPDRPVTLNLPATVEVATPNVYADQIEHMHRNLARRDSVIL
SVHPHNDRGTGVACAELAVLAGAQRVEGCIFGNGERTGNVDIATLALNLHAQGIDPMIDF
SDIDEVRRTVEYATRLDVPPRHPYAGDLVHTAFSGTHQDAIRKGFAAHRPGEWEVPYLPI
DPADLGRGYDEVIRVNSQSGKGGIAYLLETGYGVELPRRLQIDFARHVQRHTDTTGDEVT
AADLWALFEATYLTGEPAVTLAGYQTSDTGTTVTLRVDGTERTSTHEGVGPVEALVEALA
AGDITVDVLSLHQTSIGAGSDSEALTLLEHRAGGVTRWTAGRDRSVLAASLAAVLRATA
NT seq
1620 nt
NT seq
+upstream
nt +downstream
nt
atgccgtcgcacaaatatcacgatgtgtacgcccgagtcgccgtacccctgaaagaccgc
atgtggccgtcccggcgcctcaccgaggcacccctgtgggtgcccgtcgatctgcgtgac
ggcaatcaggcgctggccgagccgatggacccggcccgcaagcgccgcttcttcgagctc
atggtcgcgatgggctacaaggagatcgaggtcggctacccgtcggcgtcgcggaccgac
cacgacttcgtacgcctgatcgccgacgagcggatcgcgccgccggacgtgacggtggtc
gtcttcaccccggcgcgccccgagctgatcgagcagaccgtcgcgtcgatcgccggcatc
cccaacgacgtggtgattcacatgtacgccgcgaccgccccgctctggcgcagcgtcgtt
ctcggtcacgaccgggcgagtctcaaggagctgatcctggagggcggccggcacatcctg
aagctcgccggacacctgccgaacgtgcggttccagttctcccccgaggtgttcaacctg
accgagccggagtacgccctcgaggtctgcgacgcgatgaccgagctctgggaggcaagc
ccggaccgcccggtgaccctgaacctgcccgccaccgtcgaggtcgccaccccgaacgtg
tacgccgaccagatcgagcacatgcaccgcaacctggcccgccgggacagcgtgatcctc
tcggtgcacccgcacaacgaccgcggcaccggcgtggcctgcgccgaactggcggtcctg
gccggcgcccagcgggtcgagggctgcatcttcggcaacggcgagcggaccggcaacgtc
gacatcgccaccctggcgctcaacctgcacgcccagggcatcgacccgatgatcgacttc
tcggacatcgacgaggtacgccgcaccgtcgagtacgcgacccggctcgacgtcccgccc
cgtcacccgtacgccggcgacctggtgcacaccgcgttcagcggcacccaccaggacgcc
atccggaagggcttcgcggcgcaccgccccggcgagtgggaggtgccgtacctgccgatc
gacccggccgatctgggccgcggctacgacgaggtgatccgggtgaactcgcagtccggc
aagggcggcatcgcctacctcctggagaccgggtacggcgtcgagctgccccgccgcctc
cagatcgacttcgcccgccacgtccagcgccacaccgacaccaccggcgacgaggtcacc
gccgcggacctgtgggcgctgttcgaggcgacctacctcaccggcgagccggccgtgacc
ctggccgggtaccagacgtccgacaccggcaccaccgtcaccctgcgcgtcgacgggacc
gagcggaccagcacgcacgagggcgtcggcccggtcgaggcgctggtggaggccctggct
gccggcgacatcaccgtcgacgtgctgagcctgcaccagaccagcatcggcgccgggagc
gacagcgaggccctgaccctgctggagcaccgcgccggcggcgtgacccgctggaccgcc
ggccgcgaccgctcggtcctcgccgccagcctcgccgccgtcctgcgtgccaccgcgtga
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