Akkermansia muciniphila: Amuc_2039
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Entry
Amuc_2039 CDS
T00736
Name
(GenBank) 2-isopropylmalate synthase/homocitrate synthase family protein
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
amu
Akkermansia muciniphila
Pathway
amu00290
Valine, leucine and isoleucine biosynthesis
amu00620
Pyruvate metabolism
amu01100
Metabolic pathways
amu01110
Biosynthesis of secondary metabolites
amu01210
2-Oxocarboxylic acid metabolism
amu01230
Biosynthesis of amino acids
Module
amu_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
amu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
Amuc_2039
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Amuc_2039
Enzymes [BR:
amu01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
Amuc_2039
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
Motif
Other DBs
NCBI-ProteinID:
ACD05849
UniProt:
B2UP78
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All DBs
Position
complement(2475865..2477499)
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AA seq
544 aa
AA seq
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MSTKIFLYDTTLRDGAQSEDVNLSATDKVRIARQLDYLGMDYIEGGWPGANPVETEFFNA
MRGVGLRNAKLAAFGSTHHPSHTPETDPTLTALISSGARVAAVFGKSCPRHVEVALGISR
ERNLEIIGNSISFLKKNMEEAFFDAEHFFDGFKRDQEYALAVLRTAWEHGADCLVLCDTN
GGTMPEEISSIIRTVRERLPHALLGIHAHNDCELAVANSLAAVNSGAIQVQGTVNGIGER
CGNANLCSVIPNLQVKMKGFSCLSGASLTRLKSTAAFVSEVSNLAPFRRQPFVGNAAFAH
KGGVHVSAIMKEAALYEHIDPSLVGNAQRVLMTEQGGRSNILSLSRTLGFELEKGDPLLD
VLSAAVKKNAALGYDYVAAPASAELLFLRHMPDNALKPYFNILRTVVLTSRHEMDPDMMV
EASLKLDVHGNVEHTAAGGFGPVHALDRALRRALTRWYPELEQMHLIDYKVRVLSPTRTN
IPEAEDENGTGSNVRVLIESSDGVATWTTVGVSYNIIEASLEALADAVTYKLYKTEQARW
RAEC
NT seq
1635 nt
NT seq
+upstream
nt +downstream
nt
atgtccaccaaaatctttctctatgatactacgttgcgggacggcgcgcagagtgaagac
gtcaatttgagcgcgacggacaaggtccgcatcgcccgccagctggattatctgggcatg
gattacattgagggcggctggcccggcgccaatccggtggaaacggaatttttcaacgcc
atgagaggtgtcggactaaggaatgcaaagctggccgcctttggaagcacgcaccatcct
tcccatactccggagacggaccccacgctgaccgccctgatatccagcggtgcgcgggtg
gccgcggtttttgggaaatcctgcccccgccatgtggaagtggccctgggcatttcccgg
gaacgcaatctggaaatcatcggcaattccatttccttccttaagaaaaatatggaagaa
gccttttttgacgcagaacacttttttgacggcttcaagcgggatcaggaatacgccctg
gctgtgctccggacagcctgggaacatggagcggactgcctggtgctgtgcgataccaac
ggaggcaccatgccggaggaaatcagctccattatcaggacggtcagggaacgcctgccg
catgcccttctgggcatccacgcccacaatgactgtgaactggccgtcgccaacagcctg
gccgcggtaaacagcggagccatccaggtgcaggggaccgtgaacggcatcggggagcgt
tgcggaaatgccaatctttgttccgtcatccccaacctccaggtgaagatgaaaggcttt
tcctgcctcagcggcgcctccctgacgcggctcaaatccactgccgcctttgtctcggaa
gtatccaatctggcgcctttccggcggcagcccttcgtggggaacgccgcgttcgcccat
aagggcggagtgcatgtcagcgcgatcatgaaggaagccgctttgtacgagcacatcgac
ccctccctggtggggaacgcccagcgcgtgctgatgacggagcagggcggcaggagcaac
atcctttccctgtcccgcaccctgggttttgaactggaaaagggagacccccttctggac
gtgctttccgccgccgtgaagaaaaatgccgcgctggggtatgattacgtggccgccccg
gccagcgcggagctgctcttcctgcggcacatgccggacaatgccttgaaaccgtatttc
aacatcctgcgcactgtggtgctgacctcacgccatgaaatggacccggacatgatggtg
gaagcctccctcaagctggatgtccacggcaatgtggagcacaccgccgccgggggcttt
ggccccgtgcatgcgctggacagggctctgcgccgcgccctgacgcgctggtatccggaa
ttggagcagatgcacctcatcgactacaaggtgcgcgtgctttcccccacccggacgaac
attccggaggcggaggatgaaaacggaaccggctccaatgtccgcgtgcttattgagtcc
tcggacggcgtcgccacctggaccactgtgggcgtttcctacaacattattgaggccagc
ctggaagccctggcggacgccgtcacgtacaagctctacaagacggaacaggccagatgg
cgtgcggaatgctga
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