Amycolatopsis sp. BJA-103: BKN51_04050
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Entry
BKN51_04050 CDS
T05296
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
amyb
Amycolatopsis sp. BJA-103
Pathway
amyb00300
Lysine biosynthesis
amyb00550
Peptidoglycan biosynthesis
amyb01100
Metabolic pathways
amyb01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
amyb00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
BKN51_04050
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
BKN51_04050
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
BKN51_04050
Enzymes [BR:
amyb01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
BKN51_04050
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
NUDIX-like
DUF6093
Motif
Other DBs
NCBI-ProteinID:
AUI57472
UniProt:
A0A2N8MJ22
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Position
888994..890526
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AA seq
510 aa
AA seq
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MIVLSLAEIAGIVGGRLHRTDGTAEVTGSVEFDTREITPGGLFVALPGAKVDGHDFAARA
VESGAVAVLAAREVDAPAVIVPPLDAGVAHDRAFALVSDKDGAGAAVLAALAKLARHVIQ
KLSSDHLTVVGVTGSAGKTSTKDIIAQLLEPLGPTVAPPGSFNNELGHPWTALRADASTR
QLVLELSARGPGHIAELAAIAPPRIGVVLNVGTAHVGEFGSREGIAKGKGELVEALPSAE
DGGVAVLNLDDPYVAAMASRTSARVVFVGESESAQVRAVDITLDGEARPSFRLVTPEGEA
PVKLPLYGEHQVGNALSAAAVALEMGSTTEEIAARLSGLERRSDRRMEVSTRADGVTVLN
DSFNASPESMRAALKALASMSEQRRSWAVLGVMGDLGEDSVAAHDGIGRLVVRLNIDKLV
VIGQAAAATHQGAQQEGSWGEESVLVPDVEAAIALLHDQLRAGDVVLVKASKAAALWRVA
DAVLASPATNVETPEVAPSPSQERSNGGDA
NT seq
1533 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgtgctcagcctcgccgagatcgccggcatcgtcggcggcaggctgcatcggacc
gacggcaccgccgaggtcaccggaagcgtcgaattcgacacccgcgagatcacgccaggt
ggcttgttcgtcgcgctgccgggcgccaaggtcgacggccatgacttcgccgcgagggcc
gtcgagtccggcgccgtcgcggtactcgcggcccgcgaggtcgacgccccggccgtgatc
gtgccgccgctcgacgccggtgtcgcccatgatcgggcgttcgcgctggtctcggacaag
gacggggcgggcgccgcggtgctggccgcgctggcgaagctcgcccggcacgtgatccag
aagctttccagtgaccacctgaccgtcgtcggggtcaccggttcggcgggcaagacctcg
accaaggacatcatcgcccagctgctggagccgctcggcccgacggtggcgccgccggga
tcgttcaacaacgagctgggccacccctggacggcgctgcgggccgacgcctcgacccgg
cagctggtgctggagctgtccgcccgcgggcccggccacatcgccgagctggcggccatc
gcgccgccgcggatcggggtcgtgctcaacgtcggcaccgcgcacgtcggcgagttcggc
tcgcgcgagggcatcgccaagggcaagggcgagctcgtggaggcactgccgagcgctgaa
gacggcggcgtcgccgtcctgaacctcgatgacccgtacgtcgcggcgatggcgagccgc
acgagcgcgcgggtggtgttcgtcggcgagagcgagtccgcgcaggtccgtgccgtggac
atcaccctcgacggcgaagcacgaccgtcgttccgcctggtcactccggagggcgaggcg
ccggtgaagctcccgctctacggcgagcaccaggtcggcaacgcgctcagcgccgccgcc
gtggcactggaaatgggctcgacgaccgaggagatcgcggcgcgtctgtcgggcctcgag
cggcgctcggaccgccgcatggaggtcagcacccgggccgacggcgtcacggtgctcaac
gactcgttcaacgccagccccgagtcgatgcgggccgccctcaaggcactcgcgtcgatg
agcgagcagcgccgttcctgggcggtgctcggtgtgatgggcgacctcggcgaggactcg
gtcgcggcgcacgacggcatcggcaggctcgtcgtccggctcaacatcgacaagctcgtg
gtcatcggacaggccgccgcggccacgcaccagggcgcgcagcaggagggttcctggggc
gaggagtcggtactggtacccgacgtcgaggccgccatcgccctgctgcatgatcagctc
cgcgcgggcgacgtggtgctggtgaaggcgtccaaggccgccgcgctgtggagggtggcc
gacgccgtgctcgcctctcccgcaacgaacgttgaaacccctgaagtagccccttccccc
tctcaagaacgctcgaacggtggtgacgcgtga
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