Amycolatopsis sp. AA4: CU254_24630
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Entry
CU254_24630 CDS
T05278
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
amyc
Amycolatopsis sp. AA4
Pathway
amyc00300
Lysine biosynthesis
amyc00550
Peptidoglycan biosynthesis
amyc01100
Metabolic pathways
amyc01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
amyc00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
CU254_24630
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
CU254_24630
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
CU254_24630
Enzymes [BR:
amyc01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
CU254_24630
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Paralog
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
SH3_HelY
NirdL-like_HTH
Motif
Other DBs
NCBI-ProteinID:
ATY13271
LinkDB
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Position
complement(5314037..5315551)
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AA seq
504 aa
AA seq
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MIELSLAEIADVVGGRLHRTDGSAVVTGSVEFDTRKLGPGGLFLALPGERVDGHDFAAKA
VEAGAVGVLAAREVDAPAIVVPPLPPGQANSGSVALTGDTDGSGAAVLAALAKLARHVVD
RLAAGGLTVIGVTGSSGKTSTKDVIAQLIEPMGPTVAPPGSFNSELGHPWTALRADASTK
FLVLEMSARGVGHIAAAAETTPPRIGAVLNVGSAHVGEFGSREGIAKAKGELVEALPEDG
LAVLNLDDPLVAAMASRTKARIVGVGESAGAQIRAADITVDAEARPSFRLITPEGEAPVT
LPLHGEHHVGNALSAAAIARELGATTEEIAQRLSSLQRRSERRMEVTTRADGVTILNDSY
NANPESVRAGLKALASMSRSGRRAWAVLGVMGELGEDSVNAHDSIGRLVVRLNIEKLVVV
GQEAAAMHQGAFQEGSWGEESVLVPDVEAAVAVLHDQLRPGDVVLVKASKAAGLWRVAEA
LLADPETNTDPSLLNSERSNGGHA
NT seq
1515 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgagctgagcctggccgagatcgccgacgtcgtcggcggcaggctgcaccgcacc
gacggatccgctgtcgtgaccggcagcgtcgaattcgacacgcgcaagctgggcccgggc
gggctgttcctcgccctgcccggcgaacgcgtcgacgggcacgatttcgccgcgaaggcg
gtcgaggccggcgcggtcggcgtgctggccgcgcgggaggtcgacgccccggcgatcgtc
gtgccgccgctgccgccgggacaggccaactccgggtcggtcgcgctgaccggcgacacc
gacggctccggcgccgccgtgctggccgcgctggccaagctcgcccggcacgtcgtcgac
cggctggccgcgggcgggctgaccgtcatcggcgtcaccggctcgtccggcaagacctcg
accaaggacgtcatcgcgcagctgatcgagccgatgggcccgacggtcgcgccgcccggg
tcgttcaacagcgagctgggccacccgtggaccgcgctgcgcgccgacgcctcgaccaag
ttcctcgtgctggagatgtccgcgcgcggggtcgggcacatcgccgcggccgccgagacg
acgccgccgcggatcggcgcggtgctcaacgtcggcagcgcgcacgtcggcgaattcggc
tcgcgcgagggcatcgcgaaggccaagggcgagctggtcgaggcgctcccggaagacggc
ctcgcggtgctgaacctcgacgacccgctggtcgcggccatggcgagccgcaccaaggcc
cgcatcgtcggcgtcggggagtcggccggggcgcagatccgggccgccgacatcacggtc
gacgccgaggcccgtccgtccttccggctgatcacgcccgagggcgaggccccggtgacg
ctgccgctgcatggcgagcaccacgtcggcaacgcgctgtccgccgccgccatcgcgcgc
gagctgggcgcgaccaccgaggagatcgcgcagcggctgtcgtcgctgcagcggcgctcg
gagcggcggatggaggtcaccacccgcgcggacggcgtcacgatcctcaacgactcgtac
aacgccaaccccgaatcggtccgggccgggctcaaggcgctggcctcgatgagccgctcc
ggccgccgcgcgtgggcggtgctcggcgtgatgggcgagctgggcgaggactcggtgaac
gcgcacgattcgatcgggcgcctcgtggtccggctcaacatcgagaagctcgtcgtggtc
ggccaggaggccgccgccatgcaccagggcgcgttccaggaggggtcctggggcgaggag
tcggtgctggtacccgatgtcgaggccgcggtcgccgtgctgcatgatcagctccgtccc
ggggacgtggtgctggtcaaggcgtccaaggccgccggtctgtggcgggtggccgaagcg
ctgctggccgatccggaaacgaacaccgacccctctctcctgaactccgaacgctcgaac
ggtggtcacgcgtga
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