KEGG   Amycolatopsis sp. AA4: CU254_26530
Entry
CU254_26530       CDS       T05278                                 
Symbol
mmsA
Name
(GenBank) methylmalonate-semialdehyde dehydrogenase (CoA acylating)
  KO
K00140  malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase [EC:1.2.1.18 1.2.1.27]
Organism
amyc  Amycolatopsis sp. AA4
Pathway
amyc00280  Valine, leucine and isoleucine degradation
amyc00410  beta-Alanine metabolism
amyc00562  Inositol phosphate metabolism
amyc00640  Propanoate metabolism
amyc01100  Metabolic pathways
amyc01120  Microbial metabolism in diverse environments
amyc01200  Carbon metabolism
Brite
KEGG Orthology (KO) [BR:amyc00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00640 Propanoate metabolism
    CU254_26530 (mmsA)
   00562 Inositol phosphate metabolism
    CU254_26530 (mmsA)
  09105 Amino acid metabolism
   00280 Valine, leucine and isoleucine degradation
    CU254_26530 (mmsA)
  09106 Metabolism of other amino acids
   00410 beta-Alanine metabolism
    CU254_26530 (mmsA)
Enzymes [BR:amyc01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.18  malonate-semialdehyde dehydrogenase (acetylating)
     CU254_26530 (mmsA)
    1.2.1.27  methylmalonate-semialdehyde dehydrogenase (CoA-acylating)
     CU254_26530 (mmsA)
SSDB
Motif
Pfam: Aldedh LuxC DUF1487 Raf1_N
Other DBs
NCBI-ProteinID: ATY16631
UniProt: A0A2K8M7N6
LinkDB
Position
complement(5727568..5729061)
AA seq 497 aa
MTDRISHWIDGKPVVGSGRTGDVYDPATGQVSAQVDFAGPAEVDQAVAAAAAALPGWRGT
SLAGRTRVLFAFRELLQARKDELAKIVTSEHGKVESDAAGEVARAIENVEYACGAAQLLK
GGFSENASTGVDVYSIAQPLGVVGVISPFNFPAMVPLWFVPNALACGNTVVLKPSEKDPS
AALFIAELLAEAGLPSGAFNVLQGDKVAVDGLLAHPDVKAVSFVGSTPIARYVYETGTNH
GKRVQALGGAKNHMVVLPDADLDLAADAAVSAGFGSAGERCMAVSVVVAVEPIADELVAK
IADRMRKLRVGDGRKPSSEMGPLVTRAHHERVSSYVDTGVAEGAELVMDGRGVEADGAGE
GFWLGPTLFDRVTPSMAVYTDEIFGPVLSVARTTSFDDALALINANPYGNGTAIFTADGR
AARRFQNEVEVGMVGVNVPIPVPVGYYSFGGWKDSLFGDTHAYGPEGFHFFTRTKVVTSR
WPDTSHAGVNLGFPKNS
NT seq 1494 nt   +upstreamnt  +downstreamnt
gtgaccgaccgcatcagccattggatcgacggcaagccggtcgtcggctccggacgcacc
ggcgacgtgtacgacccggccaccggccaggtcagcgcgcaggtggacttcgccggaccg
gccgaggtggaccaggccgtggccgccgcggccgccgcgctgccgggctggcggggcacg
tcgctcgccgggcgcacgcgcgtgctgttcgccttccgcgagctgcttcaggcgcgcaag
gacgagctggcgaagatcgtgacgagcgagcacgggaaggtcgaatcggacgccgcgggc
gaggtcgcgcgcgcgatcgagaacgtcgaatacgcgtgcggcgcggcgcagctgctcaag
ggcgggttcagcgagaacgcttccacgggcgtcgacgtctactcgatcgcgcagccgctg
ggcgtggtcggcgtgatctcgccgttcaacttccccgcgatggtgccgctctggttcgtg
ccgaacgcgctggcgtgcggcaacaccgtcgtgctcaagccgagcgagaaggacccgtcc
gccgcgttgttcatcgcggagctgctcgccgaagcgggcctgccgtccggtgcattcaac
gtgctgcagggcgacaaagtcgcggtcgacgggcttctcgcgcacccggacgtcaaggcg
gtctccttcgtcggctcgaccccgatcgcccgctacgtctacgaaaccggcaccaaccac
ggcaagcgagtgcaggcgctcggcggggcgaagaaccacatggtcgtgctcccggacgcc
gacctcgacctggccgcggacgccgccgtgtccgccggtttcggctcggcgggggagcgg
tgcatggcggtttcggtggtggtcgccgtcgagccgatcgcggacgagctggtggccaag
atcgccgaccggatgcggaaactgcgcgtcggggacggccgcaagccgtcgtcggagatg
ggtccgctggtgacccgggcgcaccacgagagagtttcgtcctatgtggacaccggcgtg
gccgaaggcgcggaactcgtgatggacggccggggcgtggaagcggacggcgcgggcgag
ggattctggctcggtcccacgcttttcgaccgcgtgacgcccagtatggcggtctacacc
gacgaaatcttcgggccggtgctgtccgtcgcgcgcacgacgagcttcgacgacgcgctc
gcgctcatcaacgccaacccctacggcaacggaacggccatcttcaccgccgacggacgg
gcggcgcgccgcttccagaacgaggtggaagtgggcatggtgggcgtgaacgtgcccatc
ccggtcccggtcggctactactccttcggcggctggaaggactccctgttcggcgacacg
cacgcctacgggccggagggattccacttcttcacgcggacgaaggtggtcacgtcccgc
tggccggacacctcgcacgccggggtgaacctggggttcccgaagaactcctga

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