Amycolatopsis sp. AA4: CU254_26945
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Entry
CU254_26945 CDS
T05278
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
amyc
Amycolatopsis sp. AA4
Pathway
amyc00790
Folate biosynthesis
amyc01100
Metabolic pathways
amyc01240
Biosynthesis of cofactors
Module
amyc_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
amyc00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
CU254_26945
Enzymes [BR:
amyc01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
CU254_26945
6.3.2.17 tetrahydrofolate synthase
CU254_26945
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Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
GlnR_1st
Motif
Other DBs
NCBI-ProteinID:
ATY13662
UniProt:
A0A2K8LZ28
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Position
complement(5813273..5814952)
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AA seq
559 aa
AA seq
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MPRGEEPEETRRPDLADPDSFAGVDELGALAHSDDEDDPGNELEPDLDAPDAAYTVGGGS
RGGIGGIGQLGDNLALGPVPDLRPEDGAELHELDDEGAPAEFGDENGPEARRDLMAAEAE
LNQRWPETKLEPSLARIQALMTLLGEPNHGYPVVHVAGTNGKGSVARMVDSLLTRMGLRS
GRYTSPHLQLVTERIALDGRPVSAARYAELYQDIAPYVAMVDGASEDGVPMSKFEVLTGM
AFAAFADAPVEAAVLEAGMGGAWDATNVADAQVAVITPIGLDHTEYLGPTPADAAAEKAG
IIKPGSVAVIGEQDPEVLNVLLKRTVEVDAAVARAGSEFGVLEREVAVGGQMLKLQGLGG
VYDEIFLPLHGAHQAANAALALAAVEAFFGAGKDKQLVVEAVREAFAEVENPGRLERVRA
APAVLVDAAHNPMGARALATTIADEFNFRRLVAVVGVLADKDARGILDALEPVVSDVVVT
RSSSPRSLPVEDLAELAASIFGEDRVLAEPDLETAIETAIGLVEQNDDPEEPLAGGGVLV
TGSVVTAGDARTLFGKEPA
NT seq
1680 nt
NT seq
+upstream
nt +downstream
nt
gtgccgcgcggtgaggagcccgaggagacccggcgtccggatctcgccgatccggacagt
ttcgcgggggtcgacgaactgggcgcgctcgcgcacagcgacgacgaggacgaccccggc
aacgagctggagccggacctcgacgcgcccgacgcggcctacaccgtcggcggcggttcg
cgcggcggcatcggcggcatcggccagctcggcgacaacctggcgctcggcccggtcccg
gacctgcgtcccgaagacggcgccgagctgcacgaactcgacgacgagggcgcgcccgcc
gagttcggcgacgagaacggcccggaggcccgccgcgacctgatggccgccgaggccgag
ctgaaccagcgctggccggagacgaagctcgaaccgtcgctcgcccggatccaggcgctg
atgacgctgctcggcgagccgaaccacggctacccggtggtgcacgtcgcgggcacgaac
ggcaagggctcggtcgcgcggatggtcgattcgctgctgacccgcatgggcctgcgctcg
ggccgctacacgagcccgcacctgcagctcgtcaccgagcggatcgcgctcgacggccgt
ccggtctccgccgcccgctacgccgagctgtaccaggacatcgcgccgtacgtggcgatg
gtcgacggcgcgagcgaggacggcgtgccgatgagcaagttcgaggtgctcaccgggatg
gcgttcgccgcgttcgccgacgcgccggtcgaggccgcggtgctcgaggcgggcatgggc
ggcgcgtgggacgcgacgaacgtggccgacgcccaggtcgcggtcatcacgccgatcggg
ctggaccacaccgaatacctcggcccgacgcccgccgacgcggccgcggagaaggccggg
atcatcaagcccggatcggtcgcggtgatcggcgagcaggaccccgaggtgctgaacgtc
ctgctgaaacgcacggtcgaggtcgacgccgcggtggcgcgcgcgggcagcgagttcggc
gtgctcgaacgcgaggtcgcggtcggtgggcagatgctgaagctgcagggcctcggcggc
gtctacgacgagatcttcctgccgctgcacggcgcgcaccaggccgcgaacgcggcgctc
gcgctggccgccgtcgaggcgtttttcggggcgggcaaagacaaacagctcgtcgtggag
gcggtgcgcgaggcgttcgccgaggtcgagaacccgggccggctcgaacgcgtgcgggcc
gccccggcggtgctcgtcgacgccgcgcacaacccgatgggcgcgcgggcgctcgccacg
acgatcgccgacgagttcaacttccgccggctcgtcgcggtcgtcggcgtgctggccgac
aaggacgcgcgcggcatcctggacgcgctggagccggtggtgtcggacgtcgtggtcacg
cgcagttcgtcgccgcggtcgctgccggtcgaggacctggcggagctggccgcgtcgatc
ttcggcgaggaccgcgtgctcgccgaaccggatctggagaccgcgatcgagaccgcgatc
ggcctcgtggagcagaacgacgacccggaggaaccgctcgcgggcggcggcgtgctggtg
accggatcggtggtcaccgcgggcgacgcgcgcacgctgttcgggaaggagccagcgtga
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