Amycolatopsis sp. DSM 110486: K1T34_07325
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Entry
K1T34_07325 CDS
T10626
Symbol
pdhA
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
amyd Amycolatopsis sp. DSM 110486
Pathway
amyd00280
Valine, leucine and isoleucine degradation
amyd00640
Propanoate metabolism
amyd00785
Lipoic acid metabolism
amyd01100
Metabolic pathways
amyd01110
Biosynthesis of secondary metabolites
amyd01210
2-Oxocarboxylic acid metabolism
Module
amyd_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
amyd00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
K1T34_07325 (pdhA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
K1T34_07325 (pdhA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
K1T34_07325 (pdhA)
Enzymes [BR:
amyd01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
K1T34_07325 (pdhA)
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Motif
Pfam:
E1_dh
DXP_synthase_N
Transketolase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-ProteinID:
QYN22288
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Position
1542852..1543955
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AA seq
367 aa
AA seq
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MTTTERTAASFFLPSDEPLGLITADGAPVADAALEMPADDVLLRLHRAMVSGRRFDAQAT
ALTKQGRLAVYPSARGQEAGEIGSILALRPQDWLFPTYRDSMAVVARGVDPVEVLTLLRG
DWHCGYDPYRANVAPQCTPLATNTLHAVGFAHAAKTKGEDTVALVLLGDGATSEGDTHEA
LNFAAVWQSPVVFLVQNNGYAISVPLSKQTAAPSLAHKGVGYGMPSVLVDGNDAAAVHAV
VEQAVARAAAGGGPTLIEALTYRIESHTNADDATRYRDRAEVEAWLTRDPIARLERYLTD
RGLLDDVAREEIAVRAEAEAASLRERMNVDTVLDPADLFRHVYAEPTAALRRQAEDFTAE
LSFGAEE
NT seq
1104 nt
NT seq
+upstream
nt +downstream
nt
gtgaccaccacggaacgcaccgccgcgtcgttcttcctcccgagcgacgagcccctgggc
ctcatcaccgccgacggcgcacccgtcgccgacgccgccctggagatgcctgccgacgac
gtgctgctgcgcctgcaccgcgcgatggtgtcgggccgccgcttcgacgcgcaggccacc
gccctgaccaagcagggccgcctcgccgtgtacccgtccgcgcgcggccaggaggccggc
gagatcggctcgatcctcgcgctgcgtccgcaggactggctcttcccgacctaccgcgac
tcgatggccgtggtcgcgcgcggcgtcgacccggtcgaggtgctcacgctgctgcgcggc
gactggcactgcggctatgacccgtaccgcgccaacgtcgcgccccagtgcacgccgctg
gccacgaacacgctgcacgctgtcgggttcgcgcacgccgccaagaccaagggcgaggac
accgtcgcgctcgtgctgctcggcgacggcgccaccagcgagggcgacacccacgaggcg
ctgaacttcgcggccgtgtggcagtcgccggtggtgttcctggtgcagaacaacggttac
gccatcagcgtcccactctcgaagcagaccgcggcgccttcgctcgcgcacaagggcgtg
ggctacggcatgccgtcggtgctggtggacggcaacgacgcggccgccgtgcacgccgtg
gtggagcaggccgtcgcgcgcgccgctgcgggcggcgggccgacgttgatcgaggccctc
acctaccgcatcgagtcgcacaccaacgccgacgacgccacgcgctaccgcgaccgcgcc
gaggtcgaggcctggctcacccgcgacccgatcgcgcggctcgagcgttacctcaccgac
cgcggcctgctcgacgacgtggcgcgcgaggaaatcgccgtacgcgccgaggccgaagcc
gcgtcgttgcgcgagcgcatgaacgtggacaccgtgctcgacccggcggacctgttccgc
cacgtgtacgccgagccgacggccgcgttgcgccgccaggccgaagacttcaccgccgaa
ctctccttcggagccgaagaatga
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