KEGG   Amycolatopsis sp. EV170708-02-1: MJQ72_25485
Entry
MJQ72_25485       CDS       T10873                                 
Name
(GenBank) SDR family NAD(P)-dependent oxidoreductase
  KO
K19203  pimaricinolide synthase PimS1
Organism
amye  Amycolatopsis sp. EV170708-02-1
Pathway
amye01052  Type I polyketide structures
Brite
KEGG Orthology (KO) [BR:amye00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01052 Type I polyketide structures
    MJQ72_25485
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins [BR:amye01008]
    MJQ72_25485
Polyketide biosynthesis proteins [BR:amye01008]
 Polyketide synthase (PKS)
  Modular type I PKS
   cis-AT PKS
    Pimaricinolide synthase
     MJQ72_25485
SSDB
Motif
Pfam: ketoacyl-synt KR Acyl_transf_1 Ketoacyl-synt_C PKS_DH_N PS-DH KAsynt_C_assoc SpnB_Rossmann PP-binding CurL-like_PKS_C adh_short RhiE-like_linker Thiolase_N Epimerase Polysacc_synt_2 GDP_Man_Dehyd Docking NmrA RmlD_sub_bind ACP_syn_III
Other DBs
NCBI-ProteinID: UMO99865
LinkDB
Position
complement(5588044..5603346)
AA seq 5100 aa
MANEDKYLDYLKRATADLRETRRRLKEAEDRGHEPIAIIGMACRFPGGVRSPEDLWELVA
EGRDGISGFPADRGWDLSALYDPTGEKPGTSYCREGGFLDGAGEFDPAFFGISPREALAM
DPQQRLLLEISWETFERAGIDPGSLRGSRTGVFAGVMYHDYVSRLAAIPEELEGYLGTGN
SGSVVSGRVAYTFGLEGPAVTIDTACSSSLVALHLAAQALRQGECTMALAGGVAVMSTPD
TFVDFSRQRGLAADGRCKSYSDGADGTSWAEGVGMLLVEKLSDAQRLGHPVLAVVSGSAV
NQDGASSGLSVPNGPSQQRVIRQALENARLSAGQVDVVEGHGTGTTLGDPIEAQALLATY
GREKSADRPLWLGSLKSNIGHSQSAAGVGGVIKMVQAIRHGVLPRTLHADDPSSKVDWSA
GAVELLTEAREWPETGQPRRAGVSSFGVSGTNAHTIIEQAPESEDVAGVPPTGAVPAVLS
AKTAEALRDQVTRLRSHVLARPELSVADIAASLATTRVLHEHRGAIVAADRDQLLAGLDI
LAAGATTAGVTHGVAADGRTAFLFTGQGSQRRGMGRELAERFPVFAEAFRELCARFELPV
GELSTEELDQTANTQCALFAFEVALFRLVESWGVKPDLLAGHSIGEIAAAHVAGVFSLDD
AVKLVSARGRLMQALPTGGAMVALQATEAEVVPLLTDRVSLAAINGPESVVLSGDEDAVA
AVVSRFGDRKHKRLAVSHAFHSPLMEPMLDEFRAVAESLSYAAPRIPIVSGGKVDVSTSD
YWVRHVRDAVRFHDSVKFLAAEGVTRFLEIGPDAVLTAMAKESAGDAVVVAATRRNRAED
VTLLAAVSTLHVHGAAVDWTPLLAGARRVDLPTYAFQHRRFWLDGPLNAEGDAASLGLGA
TDHPLLGAVVTMADAHGVLLTGRLSLAAQPWLAGHVVAGHVLLPGTAFVDLVLHAGDKVD
CGIVEELTLREPLVLPEHDALSLQLVVGAPDETGRRTVGVHSRPEAADAEWSCHATGVLA
PGFPDTDFSLAAWPPEGAEPVAIDGLYGALAEVGLDYGPAFQGVRAAWTHESAVYAEIEL
ADAEKADAARFGIHPALLDSALHAAGLGALDATEARLPFSWSGVSLRAFGAKAIRVRLTP
AGPDTIALAVADPEGRPVFTADGLLVRAVPSGALTSRNPVRDALFRVDWQPLAMPAESAE
HVVASFTGYTGDLLGDAHAAAVRALELVRADQGGPKLVFLTSGAVGEAVPHPAQATVWGL
VRTAQEEFPDRFVLLDTDIEPTSELVAAAVATGEPELMLREGVLSGARLVRASRASAEPG
DIAGTVLVTGGTGALGADLARHLVRSRGVRRLLLTSRRGAAAPGADILLRELTALGADVR
IEACDAADRDALAALLADQPIALAVHAAGVLDDGLLGDLTPERLTAVLKSKVDAAVHLHE
LLGDTELVLFSSAAGVFGNEGQANYAAANAFLDALARHRHANGLPGTALAWGMWAAGMGD
SLGSRPGFPALSTEDGMALFDAATALGDAALVPIRLDLPALRARLGGDVPPLLRGLIRPT
RRAAVTGSAGALADRLAALAPAERSRELLEIVRTHVAIVLGHLGSAAIDAGKPFQELGFD
SLAAVELRNRLTEATGLRLAATLVFDYPTPLVLAEHLLEGLAGSGLAEAPETPVRTSPVD
EPIAIIGMACRYPGGVTSPEELWDLVATGRDGVSSFPVNRGWDDVYDADPGKAGKSYARE
GGFLHDAGEFDAAFFGISPREALAMDPQQRLLLETSWEVFERAGIDPHGVRGSKTGVFAG
VMYHDYAARLNSVPEDVEGYLGTGNSGSVISGRLAYTFGLEGPAVSIDTACSSSLVAMHL
AGQALRQGECSLALAGGVTVMATPNTFVEFSRQRGMATDGRCKSFAEAADGTGWGEGVGM
LLLERLSDARRNGHRVLAVVRGSAVNQDGASNGLTAPNGPSQQRVIRQALAQAGLRPSDV
DAVEAHGTGTTLGDPIEAQALLATYGQDREEPLWLGSVKSNLGHTQAAAGVAGVIKMVEA
MRHGVLPRTLHVDEPSSHVDWSDGAVSLLTETREWPDTGRPRRAGVSSFGISGTNAHTII
EAVEPEAAASGSQDVAPWPLSGKTEEALRAQAARLHDHLLANPGLSATDVAFSLTARADL
EHRAALVAGDRDGLLAALDALAHGETAEGIVRGTARHTGRTAFLFTGQGSQRLGMGIELA
ERFPVFAEAYDEVCSRFEQPIKDLTADELNQTANTQCALFALEVALFRLVESWSVRPDFL
AGHSVGEIAAAHVAGVLSLDDAVTLVSARGRLMQALPTGGAMVALRATEAEVTPLLTDRV
SIAAVNGPESVVVSGDEDAVAAVVSRFEDRKHKRLVVSHAFHSPLMEPMLEEFRAVADGL
SYAAPRIPIVSGGLADVSTSDYWVRHVRDAVRFHDSVKFLEAEGVTRFLEIGPDGVLTAM
AQDSLEDAVVVPALRRDKPEVTTLLTAVAGLHVHGADVDWGPWCAGARRVDLPTYAFQRT
EFWLDAGAAAGDLTAAGLADAGHPLLGGAVTLPDSGGTVFTGRLSLSAQPWLADHAVGET
VLLPGTAFVDLALAAGRRHGHVVLDELTLESPLVLPEHGGVELRVWVREPDDTGACAVSV
HSRADDDEPWIRHAVGTLTEDTGAAPADLTSWPPAADETDVDGLYDALADAGLNYGPVFQ
GVRAAWRDGTTVYAEIDLDERHHGDAARFGLHPALLDAALHTAGLGALSTEGGARLPFLW
SGVSFTGLGATSLRVRLTAKDDTLSLTIADGAGAPVATVAGLTVRRVDPAAFGGGADSLF
RVEWVPVRARAADVAYVVRSEVDSVTDVHEATAQTLAALQSWLADESDATLVVLTSGAVS
VAGEDTRDLARAAVWGLVRSAQSEHPGRIVLVDTDTDTDTDTADLAGAVATGESQLAIRD
GKLWAPRLAKGAPSSATPRFDPAGTVLLTGATGALGRSLARHLVSGHGVRHLLLVSRSGA
TAPGAEDLLAELTGLGASAVLESCDVADREALARLLAGIDPGHPLTAVVHAAGVLDDGLV
GSLTPERFDAVLRPKADAALNLHELAGDVDEFVLFSSAAGTFGNAGQANYAAANAFLDAL
AQHRVANGLPARSLAWGLWDTDDGMDASAAVARLTGSGLTTEEGLRLFDTAADGVVLPMK
LDVAALRAELGSDVPSLLRGLIKAPARRSAGASAWKRQLAGLSEEDRDARLLELVRTQVA
AVLGYSGPEDVPSDRAFTELGFDSLTSVDLRNRLNSATGLRLPATLVFDHPSSDAVVSRL
REELSGGAAAAAAVTTAPVDEPIAIVGMACRFPGGVRSPEDLWRLVSEGRDGITPFPADR
GWDVEGLYDPEVSRPGTSCTRYGGFLHDAGDFDPGFFGISPREALAMDPQQRLLLETSWE
AFERAGIDPATLRGSATGVFAGAMYHDYVSRLTEIPADLEGYLGTGNSGSVISGRLAYAF
GLEGPAVSIDTACSSSLVAMHLAAQALRQGECGLALAGGVAVMSTPDTFIEFSRQRGMAP
DGRIKAFSETADGTAWGEGVGMLLLERLSDARRNGRRVLAVLRGTAVNQDGASNGLTAPN
GPSQQRVIRQALAQAGLRPSDVDAVEAHGTGTTLGDPIEAQALLATYGQDREEPLWLGSV
KSNLGHTQAAAGVAGVIKMIEAMRHGILPRTLHAEEPSSHVDWSEGAVSLLSEAREWPDT
GRPRRAGVSSFGISGTNAHAVLEADGSGDAAPAGQPDVLAFPLSAKTQDALRGQAARTRA
RLLTGDAPELADVAHTLATRGLFEHRAVVTAGDRDGLLDALAALAGGEPGDFVTGVAKPG
GKLAFLFTGQGSQRAGMADELSAACPVFAQVFDEICARFDALLDRPLREALAGDLVDRTE
YTQCAMFAFEVALFRLAEGRGIRPDFLAGHSIGELAAAHVAGVWSLEDACTVVAARGRLM
QALPPGGAMIAVQATEEEIRPLVDDETVSIAAINGPVSVVVSGEEAAVTALAAGFAERGR
KTKRLTVSHAFHSPLMDGMLGEFRAVLDGISAAEPRIPLVSTLTGEPLTGDEARSSEYWV
RHVRDAVRFCDAVRTLEAHGVRRYLELGPDAPLTALGEHCVTDESTVDAPLFVPSLRAGR
SDVESFVVALARLHVDGARVDWAKALPGRKIDLPTYAFQHERFWLRPAAPAVGDVTGLGQ
SPAGHPLLGAAVEAPDSDAVLFTGRLSVQEQPWLADHVVAGTTLLPGTAFVELALRAGEL
TGCAAIDELTLEAPLVLPDHGGTALRIVAAAPDESGRRALDVYSRPEEGDWIRHATGTVS
PLAASAPFDLSAWAAADAETVETDGLYDGLAAAGLEYGPVFQGLRSAQRRGDDIWAEVDL
PEDTTTEGFGLHPALLDAALHALGFAGGGEQEADVAAGRVRLPFAWSGVRLHASGARALR
VRLSPAGENAVSLVAADETGRLVATVDALTLRPVSLEQIGGRQGSHESLFGLAWAPVPLD
PTAPVAASWAVVGVDDYKLDAALTAAGYRGQAHANLADVTDRVPELVFVSCAPDHSQGLA
AAAHTAAHRTLDLVRAWLAEDRFAGSRLVLVTGGAVDEPAQAVIWGLVRSAQSEHPGRFV
LVDLDEQDASYRVLLPALASGEPQLELREGTVKAPRLIKPAVTAAEDKAPTDGAVLITGG
TGALGAALARHLVTAHGKTRLVLAGRRGPDAPGAGELAGELRDLGAEVAVVACDAADREA
LQRLLAEHPVTGVVHAAGVLDDVVLDGLTPERLDAVLRPKVDAAVNLHELAGDVDEFVLF
SSAAGTFGNPGQANYAAANAFLDALARHRRAQGLPATSLAWGLWAGDGMAGGMSGRDLDR
MTASGAGALSTEEGLALFDLAVTAAEPVLLPMRLDLATLRAGLGADVPPLLRGLIRGTGK
RAETAGSPTGDALKAELAGMTGEERAAALLNLVATHVAAVLGHAGPEQVDPAKAFTELGF
DSLAAVELRNRVNEATGLRLPATLVFDHPTTTAVAELVGAEIVVDDAPPPLGVLAELDRL
EAAFAGGSPDDAIRGKVKDRLRALLAACDPGEGTESVADRLEDASDDEMFEFIGKELGIS
NT seq 15303 nt   +upstreamnt  +downstreamnt
gtggcgaacgaagacaagtacctcgactacctcaagcgcgcgaccgccgacctgcgggag
acccggcgacggctgaaggaggccgaggaccgcggccacgagccgatcgccatcatcggg
atggcctgccggttccccggtggcgtgcggtcgccggaggatctgtgggagctggtcgcc
gagggtcgcgacgggatctccgggttcccggccgaccggggctgggacctgtccgcgctg
tacgacccgacgggggagaagcccggcacctcgtactgccgcgagggcggtttcctcgac
ggagcgggcgaattcgacccggccttcttcgggatctcgccgagggaagcactcgccatg
gacccgcagcagcggctgctgctggagatctcctgggagaccttcgaacgcgcgggtatc
gaccccgggtccctgcggggcagccggaccggagtgttcgccggggtgatgtaccacgac
tacgtctcccggctcgccgccatcccggaggagctcgagggctacctcggcaccgggaac
tcgggcagcgtcgtttccgggcgggtcgcctacaccttcgggctggagggcccggcggtg
acgatcgacaccgcgtgctcgtcttcgctggttgcactgcatctggcggcgcaggcgctg
cggcagggcgaatgcacgatggcgctcgccggcggtgtcgcggtgatgtccacaccggac
actttcgtcgacttcagccgccagcgggggctcgccgcggacggccgctgcaagtcctat
tcggacggagcggacggcacgtcgtgggccgagggcgtcgggatgctcctggtggagaag
ctttccgacgcgcagcggctcggccacccggtgctcgccgtcgtcagcggcagcgctgtc
aaccaggacggggcgagcagcggtctcagtgtgccgaacggcccgtcgcagcagcgggtc
atccggcaggccctggagaacgcgcggctttcggccgggcaggtcgacgtcgtggagggc
cacggcaccgggaccaccctgggcgacccgatcgaggcgcaggcgctgctggccacctac
ggccgggagaagtccgcggaccggccgctgtggctgggctcgctgaagtcgaacatcggg
cattcccagtccgccgccggcgtcggcggcgtgatcaagatggtgcaggcgatccggcac
ggtgtcctgccgcgcaccctgcacgcggacgatccttcgtccaaagtggactggtcggcc
ggtgccgtcgaactgctcaccgaagcacgtgagtggcccgagaccgggcagccccgccgc
gccggcgtttcctcgttcggggtcagcggcaccaacgcgcacaccatcatcgagcaggct
cccgagagcgaagacgtcgcgggcgtgccgcccaccggcgccgtgcccgcggtcctgtcc
gccaagaccgcggaagcgctgcgcgaccaggtcacgcggctgcgctcgcacgtcctcgcc
cggccggagctgagcgtcgccgacatcgccgcgtcgctcgccaccacccgcgtgctgcac
gagcaccggggtgcgatcgtcgcggccgaccgggaccagctgctcgccggactggacatc
ctcgccgccggcgccaccaccgccggggtcacccacggcgtcgcggccgacggccggacg
gcgttcctgttcaccggtcagggcagccagcggcgcgggatgggccgggaactggccgag
cggttcccggtgttcgccgaggccttccgcgagctgtgtgcccggttcgagctgccggtc
ggcgaactgtccaccgaggagctggaccagacggcgaacacgcagtgcgcgttgttcgcc
ttcgaggtggcgctgttccggctggtggagagctggggcgtcaagcccgatctcctggcg
ggccactcgatcggcgagatcgcggcggcccatgtcgcgggcgtgttcagtctcgatgac
gccgtgaagctggtgtcggcgcgaggccgcctgatgcaggccttgcccaccggcggcgcg
atggtggcgttgcaggcgaccgaggccgaggtcgtcccgctgctgacggaccgggtttcg
ctggcggcgatcaacggcccggagtccgtggtcctttccggcgacgaagacgctgtcgcc
gccgtggtgtcccggttcggggaccgcaagcacaagcggctcgccgtgagtcacgcgttc
cattctccgctgatggaaccgatgctcgacgagttccgcgcggtcgccgaaagcctgtcg
tacgcagcgccgcggattccgatcgtgtccggtggcaaggtcgatgtgtccacttcggac
tattgggtccggcacgtccgtgatgcggtgcgattccacgattcggtcaagttcctggca
gccgagggcgtcacccggttcctggagatcggtccggacgccgtcctgaccgcgatggcc
aaggaaagcgcgggggacgcggtcgtcgtcgcggccacgcgccgcaaccgcgcggaagac
gtcacgctgctcgccgcggtctccacgctgcacgtccacggggcggccgtcgactggacg
ccgctgctcgccggtgcccgccgcgtcgacctgcccacctatgccttccagcaccgccgg
ttctggctggacggcccgctgaacgccgagggtgacgcggcgagcctcggcctgggcgcc
accgatcacccgctgctcggagccgtcgtcacgatggccgacgcgcacggtgtgctgctc
accgggcggctttccctcgccgcgcagccgtggctggccgggcacgtggtcgcgggacac
gtcctgctgccgggcaccgcgttcgtcgacctcgtcctgcacgccggggacaaggtcgac
tgcgggatcgtggaggaactgaccctgcgcgaacccctcgtcctgcccgaacacgacgcg
ctcagcctgcaactcgtcgtcggcgcgccggacgagaccggcaggcgcacggtcggcgtc
cactcccgccccgaggccgccgacgccgaatggtcgtgccacgccaccggtgtcctcgcc
cccggcttccccgacaccgacttcagcctcgccgcgtggccgcccgaaggcgccgagccg
gtcgcgatcgacggcctgtacggcgcgctcgccgaggtcggcctcgactacgggcccgcc
ttccaaggcgtccgcgccgcctggacccatgaatcggccgtctacgccgaaatcgagctg
gccgacgccgagaaggccgacgcggcccgcttcgggatccacccggccctgctcgactcg
gccctgcacgccgccggactcggcgcactggacgccaccgaagcccggctcccgttctcg
tggtccggcgtgagcctgagggccttcggagcgaaggcgatccgcgtgcggctgaccccc
gcggggccggacacgatcgcgctggccgtcgcggatccggaggggcggccggtgttcacc
gccgacggcctcctcgtccgcgcggtcccgtcgggcgctctcacctcccggaacccggtg
cgcgacgcgttgttccgggtggactggcagccgctcgccatgcccgccgaatccgctgag
cacgtcgtggcctcgttcaccgggtacaccggtgacctgctcggcgacgcccacgcggcc
gcggtccgcgcgctcgaactggtgcgtgccgatcaaggcggcccgaaactcgtcttcctg
accagtggtgccgtcggggaggccgtgccgcatccggcgcaggccaccgtctggggcctc
gtgcgcacggcgcaggaagagttcccggaccggttcgtgctcctcgacaccgacatcgag
cccacgagcgaactcgtcgcggccgccgtcgccaccggcgaacccgaactcatgctccgc
gaaggcgtcctgtccggtgcccggctcgttcgcgcctcgcgtgcctccgccgaacccggc
gacatcgcggggacggtgctggtcaccggcggcaccggcgcgctcggcgcggacctcgcc
cggcatctggtgcggtcgcgcggtgtgcggcggctgctgctcaccagccgtcgcggtgcg
gcggcccccggtgcggacatcctcctccgtgagctgaccgcgctcggcgccgacgtccgg
atcgaagcctgcgacgccgccgaccgggacgcgctcgccgccctgctcgccgatcagccg
atcgccctcgccgtgcacgcggcgggtgtgctggacgacggcctcctcggtgacctgacg
ccggagcggctcaccgccgtcctgaagtccaaagtggacgccgccgtacatctgcacgag
ctgctcggcgacaccgaactcgtcctgttctcctccgccgccggagtgttcggcaacgaa
ggacaggcgaactacgccgccgcgaacgccttcctcgacgccctcgcccggcatcggcac
gcgaacggcctgcccggcacggcactggcgtgggggatgtgggccgccggaatgggcgac
tcgctcggctcccgccccggcttccctgctctgtccacagaggacggcatggcgctcttc
gacgccgcgacggcgctcggcgacgccgcgctcgtcccgatccggctcgatctgcccgcg
ctgcgtgcgcggctcggcggcgacgtgccgccgttgctgcgcggcctgatccggcccacc
cgccgcgccgccgtcaccggttcggccggtgcgctcgccgaccggctggccgcgctcgcc
cctgccgaacggagccgggaactgctggagatcgtgcggacacatgtcgccatcgtgctg
ggccacctcggctcggcggcgatcgacgccgggaaaccgttccaggagctcggcttcgac
tcgctggcggcggtcgaactgcgcaaccggctgaccgaggccaccggcctgcggctggcc
gcgaccctcgtcttcgactacccgacaccgctcgtgctcgccgaacacctgctggagggg
ctcgccgggagcgggctcgcggaagcaccggaaacgccggtgcgcacgagtccggtcgac
gagccgatcgcgatcatcggcatggcctgccgctatccaggcggtgtcacttctccggaa
gagctgtgggatctcgtggccaccggccgtgacggggtctcgtcgttcccggtcaaccgg
ggctgggacgacgtctacgacgcggaccccggcaaggcaggcaagagttacgcccgcgag
ggcggtttcctgcacgacgcgggcgaattcgacgcggcgttcttcgggatctcgccgcgc
gaggcgctggcgatggatccgcagcagcggttgctgctggagacgtcgtgggaggtcttc
gaacgcgccgggatcgatccgcacggggtgcggggaagcaagaccggcgtcttcgccggg
gtgatgtaccacgactacgcggcgcggctgaactccgtgccggaggacgtcgagggctat
ctcggcacgggcaactcgggcagcgtgatctcgggacggctggcctacacgttcgggctg
gaaggccccgcggtgagcatcgacacggcctgttcgtcctcgctggtcgcgatgcacctc
gccggacaggctttgcggcagggcgaatgttcgctcgcgctcgccgggggcgtgaccgtg
atggcgacgccgaacaccttcgtcgagttcagccgacagcgtgggatggccaccgacggc
cggtgcaaatccttcgccgaggccgcggacggcaccggctggggcgaaggcgtcggcatg
ctcctgctggagcgcctttcggacgcccgccgcaacggccaccgggtgctggccgtggtc
cgcggttcggcggtgaaccaggacggcgcgtcgaacggcttgacggcgccgaacgggccg
tcgcagcagcgcgtgatccgtcaggctttggcgcaggcgggcttgcgtccgtccgatgtg
gacgccgtggaagcgcacggtacgggaacgactcttggcgatccgatcgaggcgcaggct
ttgctggccacgtacgggcaggatcgtgaggagccgttgtggctgggttcggtgaagtcg
aacctcgggcacacgcaggcggccgccggtgtcgcgggtgtgatcaagatggtcgaggcg
atgcggcacggcgtgctgcccaggacgttgcatgtcgatgagccttcgtcccatgtggac
tggtccgatggcgcggtctccctgctcaccgagacgagggagtggccggacaccggacgt
ccgcgacgcgccggggtgtcgtcgttcgggatcagcgggaccaacgcgcacacgatcatc
gaggccgtcgagccggaagccgccgcgtccggaagccaggatgtcgcgccgtggccgctg
tccggcaagaccgaggaagcgttgcgcgcgcaggcggcccgcctccacgaccatctgctg
gccaatcccggcctgagcgcgacggacgtcgcgttctcccttacggctcgggcggatctg
gagcaccgggccgcgctcgtggccggtgaccgcgacggtctcctggccgcactggacgcg
ctcgcgcacggcgagaccgccgaggggatcgtccggggaacggcccggcacaccggccgg
acggcgttcctgttcaccggtcagggcagccagcggctcgggatgggtattgagctggct
gagcgcttcccggtgttcgccgaggcttacgacgaggtgtgttcccggttcgagcagccg
atcaaggacttgacggccgacgaactgaaccagaccgcgaacacgcagtgtgcgttgttc
gctcttgaggtggcgctgttccggttggtggagagctggagtgtccggccggacttcctg
gcggggcattcggtcggtgagatcgccgccgcgcatgtcgcgggtgtgctgtccctcgac
gacgcggtgactttggtgtctgctcgtggtcggttgatgcaggcgctgcccacgggcggc
gcgatggtggcgctgagggcgacggaagccgaggtgaccccgctgctgaccgatcgggtg
tcgatcgccgccgtcaacggcccggaatcggtggtcgtctcgggtgacgaagacgccgtc
gccgctgtggtctctcggttcgaggaccgcaagcacaagcggctcgtggtcagccacgcc
ttccattcgccgttgatggagccgatgctggaggagttccgcgcggtcgccgacggcctg
tcgtatgcggcgccgcggattccgatcgtgtcgggtggtctggcggatgtgtccacttcg
gactattgggtccgtcacgtccgtgacgcggtgcggttccacgattcggtgaagttcctg
gaagccgaaggtgtcacgcggttcctggagatcggtccggacggcgtgctgaccgcgatg
gcccaggacagcctggaggacgcggtcgtcgtccccgccctgcgacgcgacaaacccgag
gtgacgaccctgctgacggcggtggccggactgcacgtccacggcgccgacgtcgactgg
ggcccgtggtgcgccggtgcccgccgggtggatctgcccacgtatgccttccagcgcacg
gagttctggctcgacgcgggtgccgcggccggcgatctgaccgcggcgggactggccgac
gccgggcatccgctgctcggtggcgcggtgaccctgccggattccggcgggaccgtcttc
actggcaggctgtcgctctcggcccagccctggctcgccgaccatgccgtcggggagacc
gtgctcctgcccggaaccgcgttcgtcgatctggcgctcgccgccggacggcggcacggc
cacgtcgtcctcgacgaactcaccctggagagcccgctggtcctgccggagcacggcggt
gtcgagctgcgcgtgtgggtccgcgaaccggacgacaccggcgcgtgcgcggtcagcgtg
cattcccgcgccgacgacgacgaaccctggatccgccacgcggtcgggacgctgaccgag
gacaccggcgccgcccccgccgacctgacgtcgtggccgcccgccgccgacgagaccgac
gtcgacggcctgtacgacgcgctcgccgacgcgggcctgaactacggcccggtgttccaa
ggtgtccgcgccgcctggcgcgacggcacgacggtgtacgccgagatcgatctcgacgaa
cgtcaccacggcgacgccgcccggttcggcctgcacccggcgctgctggacgctgccctg
cacaccgccgggctcggcgcgctgagcaccgaaggcggggcccggctgcccttcctgtgg
tcgggtgtctcgttcaccggcctcggcgccacgagcctgcgcgtccggctcaccgcgaag
gacgacacgctctccctgacgatcgcggacggggcgggggcgccggtggcgaccgtcgcc
gggctgaccgtccgccgggtcgaccccgccgcgttcggtggcggcgccgactcgctgttc
cgggtggagtgggtcccggtccgtgcccgtgccgcggacgtcgcatatgtcgtccggtcc
gaagtggacagtgtgacggacgtgcacgaggcgacggcgcaaacgcttgcggcgctccaa
tcctggctcgccgacgaaagcgacgccaccttggtcgtgctgaccagcggcgccgtgtcg
gtggcgggagaggacacgcgtgatctcgcccgcgccgccgtctgggggctggtgcggtcg
gcgcagtccgagcacccgggccggatcgtgctcgtcgacaccgacaccgacaccgacacc
gacacagcggacctggccggggccgtcgccaccggcgagtcacagttggccatccgcgac
gggaagctctgggcgccgcgtctggcgaagggcgcgccctccagtgccacaccgcgtttc
gacccggccgggaccgtcctgctcaccggggccaccggcgcgctgggccgatcgctggcc
cggcacctggtctccggacacggcgtgcggcacctgctcctggtcagccgcagcggcgcg
accgcccccggcgccgaggacctgctggccgaactgaccgggctcggcgcctccgcggtc
ctggagtcctgcgacgtcgccgaccgggaagccctcgcgcggctgctggccgggatcgac
cccggacatccgctcaccgccgtggtgcacgcggccggcgtcctcgacgacggcttggtc
ggcagcctgacccccgaacggttcgacgccgtcctacggcccaaggccgacgcggcgctg
aacctgcacgaactggcgggcgacgtcgacgagttcgtgctgttctcgtcggcggcggga
acgttcggcaacgccgggcaggcgaactacgccgcggcgaacgccttcctggacgcgctg
gcacagcaccgggtggccaacgggctcccggcccggtcactggcctggggcctgtgggac
accgacgacgggatggacgcttccgccgccgtcgcgaggctcaccggttccggcctcacc
accgaagaagggctgcgcctgttcgacaccgcggccgacggcgtcgtcctgccgatgaag
ctcgacgtcgccgcgctccgcgccgaactcggctccgacgtgccgtccctgctgcgcggg
ctgatcaaggcgcccgcgcggcgctccgccggggcgtcggcgtggaagcggcagctcgcg
ggactgtccgaagaggaccgtgacgcgcgcctgctcgaactcgtgcggacacaggtcgcc
gcggtgctgggctactccggcccggaggacgtgccgtcggaccgggcgttcaccgaactc
ggcttcgattcgctcacgtcggtggacctgcggaaccggctgaactcggcgaccggcctg
cgcctgcccgccaccctcgtgttcgatcacccgagctccgacgcggtggtctcccgcctg
cgggaggaactgtccggcggcgcggcggcggccgccgccgtcaccacggcaccggtcgac
gaaccgatcgccatcgtcggcatggcctgccggttccccggcggtgtccggtccccggaa
gacctctggcgtctggtcagcgaaggccgtgacggcatcaccccgttcccggcggaccgg
ggctgggacgtcgaaggcctgtacgaccccgaggtcagcaggccgggcacctcctgcacc
cgctacggcggattcctgcacgacgccggggacttcgaccccgggttcttcgggatctcg
ccgcgtgaggcgctggcgatggacccgcagcagcggttgctgctggagacgtcctgggag
gccttcgaacgcgccgggatcgacccggccaccctgcgcggctccgcgaccggtgtgttc
gccggggcgatgtaccacgactacgtttcgcgactcaccgagatcccggcggatctggag
ggctacctcggcacggggaactcgggcagcgtgatctcgggacgtctcgcctacgccttc
gggctggaaggcccggcggtcagcatcgacacggcgtgttcgtcctcgctggtcgcgatg
catctggcggcgcaggcgctgcggcagggcgaatgcggcctggcgctggccggcggtgtc
gcggtgatgtccactccggacactttcatcgagttcagccgccagcgcgggatggcgccc
gacggccggatcaaggcgttctccgagaccgcggacggcacggcctggggcgagggcgtc
ggcatgctgctgctggaacggctttcggacgcccgccgcaacggcaggcgggtgctggcc
gtcctgcggggcacggcggtgaaccaggacggcgcgtcgaacgggctcaccgcgccgaac
gggccgtcgcagcaacgcgtgatccgtcaggcactggcacaggcgggcttgcgtccgtcc
gatgtggacgccgtcgaggcgcacgggaccgggacgacactcggtgacccgatcgaggcg
caggctctgctggccacctatgggcaggatcgggaggagccgttgtggctcggctcggtg
aagtccaacctcggtcacacacaggccgccgccggggtggcgggggtgatcaagatgatc
gaggccatgcgccacgggatcctgccgcgcaccctgcacgccgaagaaccatcgtcccat
gtggactggtccgaaggcgcggtctccctgctcagcgaagcacgtgagtggccggacacc
ggacgtcctcggcgcgccggggtttcgtcgttcgggatcagcgggaccaacgcgcacgcc
gtcctcgaagcggacggctccggggacgcggcaccggccggtcagccggacgtactcgcc
ttcccgttgtccgccaagacccaggacgctttgcgcgggcaggcggccaggacgcgtgcc
cggttgctgaccggagacgcgcccgagctcgccgacgtcgcgcacaccctcgcgacacgg
ggacttttcgagcaccgggcggtggtcaccgccggtgaccgcgacgggctgctcgacgcg
ctggccgcgctggccgggggagaaccgggcgacttcgtcaccggtgtggcgaaaccgggc
gggaaactcgcgttcctcttcaccggccagggcagccagcgcgccgggatggccgacgag
ctctcggctgcctgccccgtcttcgctcaagtcttcgacgagatctgcgcgcgtttcgac
gccctgctggaccgcccgctgcgcgaggcgctcgccggtgacctggtcgaccgcaccgaa
tacacccagtgcgcgatgttcgccttcgaggtcgcgctgttccggctcgccgagggccgg
ggcatccggccggacttcctggccgggcattcgatcggggaactggcggcggcccacgtc
gccggggtctggtcgctggaggacgcctgcaccgtggtcgccgcgcgaggcaggctcatg
caggcgctaccgccgggcggtgcgatgatcgccgtccaggccaccgaggaggagatccgg
ccgctggtcgacgacgagaccgtgtcgatcgccgcgatcaacggcccggtgtcggtggtc
gtctccggcgaagaggccgccgtgaccgcgctggccgccgggttcgccgaacgcggccgc
aagaccaaacggctcaccgtgagccacgcgttccactcgccgctcatggacgggatgctc
ggcgagttccgcgccgtgctcgacgggatttcggccgccgaaccgcggatcccgctggtg
tccacactgaccggcgagccgctgaccggcgacgaagcacggtcgagcgagtattgggtc
cggcacgtgcgggacgcggtgcgattctgtgacgcggtccggacgctggaggcgcacggc
gtccggcgttacctggaactcggcccggacgcgccgctgaccgccctcggcgagcactgc
gtcacggacgagtccactgtggacgccccgctgttcgtgccgtcgctgcgcgccggccgg
tcggatgtcgagtcgttcgtcgtcgcgctcgcgcggctgcacgtcgacggtgcccgggtc
gactgggcgaaggcgctccccggccggaagatcgatctgcccacctatgccttccagcac
gagcggttctggctgcggcccgccgcgcccgcggtcggcgacgtcaccggactggggcag
tcgcccgccgggcatccgctgctcggtgcggcggtcgaggcgccggacagcgatgcggtg
ctgtttaccggcaggctgtcggtgcaggagcagccgtggctggccgaccacgtcgtcgcc
gggacgaccctcctgccgggtacggcgttcgtcgaactcgcgctgcgagccggtgagctg
accggttgcgcggccatcgacgaactgaccctggaagcgccgctggtgctgccggaccac
ggcggtacggcgctgcggatcgtcgccgccgcaccggacgagtccggcaggcgcgcgttg
gacgtctactcccgccccgaggagggcgactggatccgccacgccaccggcaccgtgtca
cctctggcggcgagcgcgccgttcgatctgtcggcatgggcggccgccgacgccgagacc
gtcgaaaccgacggcctctacgacggcttggccgccgccggtctcgagtacggcccggtc
ttccagggactccgctccgcccagcggcgcggggacgacatctgggccgaggtcgaccta
cccgaggacaccacgaccgagggcttcggcctgcatccggcgttgctcgacgccgccttg
catgccctgggcttcgccggaggaggcgagcaggaggccgacgtggcggccggccgtgtg
cgcctgccgttcgcctggtccggcgtccggcttcacgcctccggtgcgcgcgccctgcgg
gtccggctgtccccggcgggggagaacgcggtctcgctggtcgccgccgacgagaccggc
aggctggtggccacagtggacgccctgacgctgcgtccggtctcgctggagcagatcggc
gggcggcagggcagccacgagtcgctgttcggcctggcctgggcgccggtcccgctcgat
cccaccgccccggtggccgcgagctgggccgtcgtcggtgtggacgactacaaactcgac
gccgcgctcaccgccgccggctatcgcgggcaggctcacgcgaatctggccgacgtgacc
gatcgggtgccagagctggtcttcgtgtcttgcgcgccggaccacagccaaggcctggcc
gccgccgcgcacaccgccgcccaccgaacgctggacctggtccgtgcgtggctggccgag
gaccggttcgccggttcccggctggtgctggtcaccggtggtgccgtcgacgaaccggcg
caggcggtgatctggggcctggtccgctcggcgcaatccgagcaccccggccggttcgta
ctggtcgacctcgacgaacaggacgcgtcgtatcgcgtgctgctgcccgccctcgcctcc
ggcgaaccgcagctggagttgcgcgagggcacggtgaaggcgccgcggctgatcaaaccg
gccgtgacggccgcggaagacaaggcgccgacggacggggccgtgctgatcaccggcggc
accggcgcgctcggcgcggcactggcccggcatctggtcaccgcgcacgggaagacgcgg
ctggtgctcgccggccgccgcggcccggacgcgccgggcgcgggcgagctggccggcgaa
ctgcgcgatctgggcgccgaggtcgcggtggtcgcttgcgacgcggccgatcgtgaagcg
ctgcaacgacttctggccgagcacccggtgaccggcgtcgtccacgccgccggtgtgctc
gacgacgtcgtcctcgacggcctcaccccggaacggctcgacgccgtcctgcggccgaag
gtcgacgccgcggtgaacctgcacgaactggcgggcgacgtcgacgagttcgtgctgttc
tcctccgcggcgggcaccttcggcaatccgggacaggcgaactacgcggcggccaacgcg
ttcctcgacgcgctcgcccggcatcgccgtgcgcaggggctgcccgcgacgtcgctcgcc
tggggcctctgggccggtgacgggatggcgggcggcatgtccggacgcgacctggaccgg
atgacggcctccggcgcgggcgcactgtccacagaggagggactggcgctgttcgacctc
gcggtgacggcggccgaaccggtcctgttgccgatgcggctggacctcgccaccctgcgg
gccggcctcggcgccgacgtcccgcccctgctgcgcggcctgatccgcggtaccggcaaa
cgcgccgagaccgccggttcgccgaccggggacgcgctcaaggccgagctggccgggatg
accggggaggaacgcgccgcggcactgctgaacctcgtcgccacgcatgtcgccgcggtc
ctcgggcacgccggccccgaacaggtcgatccggccaaggcgttcacggaactcgggttc
gactcgctcgccgcggtcgaactgcgcaaccgggtcaacgaggccaccggcctgcggctg
cccgcgacgctggtcttcgaccatccgaccaccaccgcggtggcggaactggtcggcgcg
gagatcgtcgtggacgacgcgccaccgccgctgggggtgctggcggaactcgaccggctg
gaggcggcgttcgccgggggaagcccggacgacgcgatccgcggcaaggtcaaggaccgg
ctgcgtgccctgctcgcggcctgcgatccgggcgagggcaccgaatccgtggcggatcgg
ctcgaagacgcctcggacgacgaaatgttcgaattcatcggcaaggaactcgggatctcc
tga

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