Amycolatopsis sp. EV170708-02-1: MJQ72_30080
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Entry
MJQ72_30080 CDS
T10873
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
amye Amycolatopsis sp. EV170708-02-1
Pathway
amye00290
Valine, leucine and isoleucine biosynthesis
amye00660
C5-Branched dibasic acid metabolism
amye01100
Metabolic pathways
amye01110
Biosynthesis of secondary metabolites
amye01210
2-Oxocarboxylic acid metabolism
amye01230
Biosynthesis of amino acids
Module
amye_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
Enzymes [BR:
amye01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
MJQ72_30080 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
MJQ72_30080 (leuC)
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Motif
Pfam:
Aconitase
AcnX
Motif
Other DBs
NCBI-ProteinID:
UMP00707
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Position
complement(6618816..6620234)
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AA seq
472 aa
AA seq
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MPRTLAEKVWESHLVRRGEGAEPDLLYIDLHLLHEVTSPQAFDGLRLAGRKLRRPDLTIA
TEDHNVPTIDIELPIADPVSRTQVDTLRANCKEFGVRLHPMGDAEQGIVHVIGPQLGLTQ
PGMTVVCGDSHTSTHGAFGAMAFGIGTSEVEHVMATQTLPLRPFKTMAITVDGQLRPGVT
AKDIILAVIAKIGTGGGQGYVLEYRGEAIEKLSMEARMTVCNMSIEAGARAGLIAPDETT
FAYLKGRPHAPQGADWDAAVENWRELRTDDDAVFDAEVRLNADELTPFVTWGTNPGQGLP
LGAEVPDPERIGDENERIAAEKALSYMDLKPGTPLREIAVDTVFLGSCTNGRIEDLRAAA
DVLRGHKVADSVRMLVVPGSMRVRQAAEAEGLDKVFTEAGAEWRQAGCSMCLGMNPDQLK
PGERSASTSNRNFEGRQGKGGRTHLVSPLVAAATAVRGTLSSPEDLQPAAAR
NT seq
1419 nt
NT seq
+upstream
nt +downstream
nt
atgccccggacactggccgagaaagtgtgggagtcgcacctggtgcggcgcggcgagggg
gccgagcccgacctgctctacatcgatctccacctgctgcacgaggtcaccagcccgcag
gcgttcgacggactgcgcctggccggccggaaactgcgccgccccgacctcaccatcgcg
accgaggaccacaacgtcccgacgatcgacatcgagctgccgatcgcggatcccgtttcc
cgtacccaggtcgacacccttcgcgccaactgcaaggagttcggtgtccggctgcacccg
atgggcgacgccgagcagggcatcgtgcacgtcatcggcccgcagctgggcctgacccag
cccgggatgaccgtggtgtgcggcgacagtcacacctcgacgcacggggccttcggcgcc
atggccttcggcatcggcacctccgaggtcgaacacgtgatggccacgcagaccctgccg
ctccgtccattcaagacgatggcgatcacggtcgacggccaactgcggcccggcgtcacg
gcgaaggacatcatcctggcggtgatcgcgaagatcggcaccggcggcgggcagggctac
gtcctcgagtaccgcggcgaagccatcgaaaagctgtcgatggaagcccggatgacggtg
tgcaacatgtccatcgaagccggtgcgcgcgccgggctcatcgcgccggacgagacgacg
ttcgcgtatctgaagggccgtccgcacgccccgcagggcgcggactgggacgccgccgtc
gaaaactggcgcgaactgcgcaccgacgacgacgccgtcttcgacgccgaggtgcgcctg
aacgccgacgagctcacgcctttcgtgacgtggggcacgaacccgggccaggggctcccg
ctgggcgccgaggtgcccgacccggagcgcatcggcgacgagaacgagcgcatcgccgct
gagaaggccctgtcctatatggacctgaagccgggcacgccgctgcgtgagatcgcggtg
gacaccgtcttcctcggctcgtgcacgaacggccggatcgaggatctgagggccgccgcg
gacgtcctgcgcgggcacaaggtcgccgattcggtgcggatgctcgtcgtccccggctcg
atgcgcgtccgccaggcggcggaagccgaagggctggacaaggtcttcaccgaagcgggc
gcggaatggcgtcaggccggctgctcgatgtgcctcggcatgaacccggaccagctcaag
ccgggcgagcgcagcgcgtcgacctcgaaccgcaacttcgaaggcaggcagggcaagggc
ggccggacgcatctggtctcgccgctcgtggcggccgccacggccgtgcggggaacgctg
tccagccccgaagacctgcagcccgccgccgcccgctga
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