Amycolatopsis sp. CA-230715: HUW46_01941 Help Entry HUW46_01941       CDS       T10444                                  Symbol fadA_3 Name (GenBank) 3-ketoacyl-CoA thiolase   KO K19208   candicidin polyketide synthase FscE Organism amyz  Amycolatopsis sp. CA-230715 Pathway amyz01052   Type I polyketide structures Brite KEGG Orthology (KO) [BR:amyz00001]  09100 Metabolism   09109 Metabolism of terpenoids and polyketides    01052 Type I polyketide structures     HUW46_01941 (fadA_3)  09180 Brite Hierarchies   09181 Protein families: metabolism    01008 Polyketide biosynthesis proteins [BR:amyz01008]     HUW46_01941 (fadA_3) Polyketide biosynthesis proteins [BR:amyz01008]  Polyketide synthase (PKS)   Modular type I PKS    cis-AT PKS     Candicidin PKS      HUW46_01941 (fadA_3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  ketoacyl-synt Acyl_transf_1 KR Ketoacyl-synt_C PKS_DH_N PS-DH KAsynt_C_assoc ADH_zinc_N_2 PP-binding adh_short SpnB_Rossmann CurL-like_PKS_C Epimerase ADH_zinc_N Thiolase_N ADH_N RhiE-like_linker PKS_DE NmrA GDP_Man_Dehyd Docking Polysacc_synt_2 SDR ACP_syn_III SAT AbiEi_3 RmlD_sub_bind AlaDh_PNT_C Motif Other DBs NCBI-ProteinID:  QWF78545 UniProt:  A0A975MV15 LinkDB All DBs Position complement(2055064..2072052) Genome browser AA seq 5662 aa AA seqDB search MSGEEKFLEYLKRVTADLRETRQRLREVEEQASEPLAVIGMSCRLPGGVRTPEGLWRLLA DGGDAISGFPADRGWDLDGLFDADPDAEGTSYTRQGGFIHDAADFDPVFFGISPREALAM DPQQRLLLEGAWETFERAGIDPSTLRGSKHGVFVGAYGQGYGNALGYSGESIEGYVATGT AGSIISGRVAYQLGLEGPAVTVDTACSSSLVALHLAGQALRTGECSMALVAGAAVMAVPT GFTEFSRQRGLAADGRCKPFSESADGTSWGEAVGLILVERLSEARKNGHEVLAVVRGSAV NQDGVSNGLTAPNGRAQQRVIREALKNAGLSAAEVDAVEAHGTGTTLGDPIEAQALLATY GQGRPEGQPLWLGSVKSNFGHTQAAAGVVGVIKMILAMREGVLPKTLHLDEPSHRVDWDS GAVSLLTEQTPWPVTGRPRRAGVSSFGFSGTNSHVILEQPEPVEAEAIERGAAPVALPWL VSGKTADGLRAQAANLRSHVDGDLVDVAFSLATTRAALENRAVVIGRDRDDFLSALNTLA EEDATSTAVRGVADVRGKVVFVFPGQGSQWIGMAVDLLGTSPVFAERFAECERALSSFVD WSLTEVVGDEAALERVDVVQPVLWAVMVSLAAVWRSYGVEPAAVVGHSQGEIAAAVVAGA LSLEDGARVVALRSQAIRDELAGKGGMVSVAQPESAVAERISRFGDRVAVAAVNGPGTTV IAGEPDALAEILAECEAEEVRARRIAVDYASHTPQVESIRDRLLEVLAPIQPRAAEVAFF STLTADWQDTTGLDARYWVENLRHTVKFEQATRALAEQGYRFFVESSAHPVLTMSVQETL DTTDDADGVAIGSLRRDEGGLARFLTSLAEGYVRGLAVDWTPAFPAGARRVDLPTYAFQR QSLWPKANPALVAGDVSSVGQGSADHPLLGAVVAIADGDGHLLTGRLSVQTHPWLADHAV GGTILLPGTAFVELAIRAGDQAGCDLVEELTIEAPLVLPERGGVQIQLIVSAPDETGRRA LTLHSRPEDADQPWTRHASGSLGTGHVDHADLTAWPPPGAEEIDGVRDGMYDRMAERGYG YGPAFQGLRAAWRRDGDVFAEVTLPDEQRADAPGFGLHPALLDAALHAIGIGGLLADPDE VKLPFAWSDVSLAATGASSLRVHLSPSGTDAVSLRLADATGAPVASIGSLVLRPLSTGQL GSARSAGADSLFRVDWTELPLPDPVVDIAALGADALGIAGAGTYADLTALAEAIEHGAAV PGAVLTELPEVSSVDAVGVRTSTNLVLDLMQRWLAEDRFADSKLVLLTKGAVLGDGATDL VAAPAWGLVRSAQSENPGRFVLADVDDTAGAALAAALATDEPQLALRNGTLYVPRLARAA AGSALAPSAPVWRLDSTATGTLDTLALVDNSEALRPLAAGEVRVEVRAGGVNFRDVLIAL GMYPGDANMGSEAAGVVVETGSEVTDLAVGDRVFGVFHHGFAPVAVADRRIIAPIPEGWS FEQAATTPIVFLTAYYGLTRLAGLRAGETVLVHAGAGGVGMAAIALARHLGAEVFATASP GKWDVLRSLGVDDEHLASSRDLDFEAKFRAATGDRGIDVVLDSLAGEFVDASLRLTAPGG RFVEMGKTDVRDPARVAAEHEVSYQAFELFQAGEDALGRMLAELLDLFGRGVLRPLPVTT WDVRRAKDAFRHLSQAKHVGKVALVMPRALASEGTVLVTGGTGLLGGLLARHLVTEHGVR HLLLTSRRGEAAEGAAELRAELTALGATVTIAACDAADRAALANLLATIPAEHPLTGVVH TAGVLDDATITSLTPERLDAVLRPKVDAALNLHELTEDLDLAAFVLFSSAAATFGSPGQG NYAAANAFLDALAHRRRAEGRAAQSLAWGLWQQRSGMTGHLGGSRGSELSTEHGLALFDL SSTMDEPVLVPIPLDLRALSAGPVPAFLRGLVSSPHRRAAANSAETDLTGLAGRLAGLSE RDQEEALLELLRANAAAVLGLPPNVVEAAKPFRDIGFDSLTAVELRNRLATATGTRLPAT LVFDYPTPTVLAKHLRTELLGADLPVTTGTAAGAATDGEPIAIVAMSCRFPGGAHSPDRL WQLVTEGGDAVSAFPPDRGWFAEGAGSEFTGAGGFVYDADRFDAGFFGISPREALAMDPQ QRLLLESSWEVLERAGIDPESLRGTQTGVFAGAAHNGYATGIHEMPEGIEGYLMTGTTGS VVSGRVAYTFGLEGPAVTVDTACSSSLVALHLACQSLRAGECSMALAGGVTVLSTPGLFA EIGKQGGLAPDGRSKAFSEDADGMGAAEGVGMLLVERLSDAQRNGHPILAVVRGSAINQD GASNGLTAPNGPSQQRVIRQALANARLEASDVDAVEAHGTGTALGDPIEAQALQATYGRD RERPLWLGSLKSNIGHTTAAAGVAGVIKMVQALRHGVLPKTLHVERPTSHVDWSASAVTL LTEEIGWPETGAPRRAGVSSFGISGTNAHAILEQAPATEEAPGPVEAPAVLPWVLSAKTG GALPAQAATLKSYLDTRPDLAPVDVGFSLVSSRAALDHRAVVIGDPAALLAGLDAMAGGG SAAQLVTGVADVRGKVVFVFPGQGSQWVGMAVDLLSSSAVFASRFAECERALSSFVDWSL TEVVGDEAALERVDVVQPVLWAVMVSLAAVWRSVGVEPAAVVGHSQGEIAAAVVAGALSL EDGARVVALRSQAIRDELAGKGGMVSVAQPESAVVERIARFGDRVAVAAVNGPGTTVIAG EPEALAEILAECEAEEVRARKIAVDYASHTPQVESIRDRLLDVLSPIQPRGTEIGFFSTL TGDWQDTTGLDARYWVENLRHTVKFEQTTRALSEQGYGFFVESSAHPVLTMSVQETLDTL ETEGVAVGTLRRNEGGVDRFLISLAEGYVRGLRVDWAPVFPSGARRVELPTYAFQRQRFW LESTASASGLMTTDVVEARFWDAVENEDLEALAGTWEIDGDRPFSEVLPVLSSWRRQRRQ QSTVDQWRYGVTWKPLTTAAARLSGTWLLITESEEAAWFADALRAHGADVVTVEAGELSA RITELGEIAGAVSLASGAAETLVVVQALLDSTVAAPVWIATRGAVSVGRSDRAADPELAQ IWGLGRILGLEHPDRWGGLLDLPASSDSRAAARVVAVLAGIGDEDQVAVRDSGVFARRLT RSPLAEREPVREWSPRGTVLVTGGTGALGGHVARWLAANGAEHLVLTSRRGRDADGAVEL ETELSGLGARVTIVACDAADRDALAVVLAEHGPFSAVVHAAGVGEFAPLTDTTIEDLSRI ISAKVDGARNLDELLGDAELDAFVLFSSNAGVWGGGTQGAYAAGNAFLDALAEQRRAREV TATSIAWGAWGGSGLAASDAAEDTLRRRGVLPMAPEAAVAALVQSVEHDETFVAVADVDW ARFVPGFTAARPRPLISDIPEARHALDSAGEETGADSSALAEKLAGLSEVERQRAVLDVV RAEAAAVLGYASAEEVERGRAFRDMGFDSLTAVELRNRLSTATGLKLPTTLVFDYPNSVV LSEFLVREVTGARQGVATASTVSAAADEPIAIVGMSCRYPGGVNSPEELWQLVENGGDAL SALPGDRGWNLPELLGSDLADSIEGGFLYDVGEFDAALFGISPREALAMDPQQRLLLEAS WEVCERAGIDPSSLRGTRTGVFAGASNSAYGFGLGQLPDGVEGYMLTGSSGSVVSGRVSY TLGLEGPAVTVDTACSSSLVALHLACQALRAGECSLALAGGVAVMVVPGAFAEFGRQGGL AADGRCKSFAEAADGTGWGEGVGMLLVERLSDARRNGHEVLAVVRGSAINQDGASNGLTA PNGPSQQRVIRDALANAGLTPSDVDAVEAHGTGTVLGDPIEAQALLATYGQERERPLFLG SVKSNIAHTQAASGVAGVIKMVLAMRNGVLPKTLHVDEPSSHVDWSAGAVSLLTENAEWP ETGAPRRAGVSSFGVSGTNAHTIVEQAPKVEEPVVVDHSPANRPLPWALSGKSQDAVRAQ AARLLSHVDGLNEADVAYSLATTRASLDHRAVVVGADHDEFVAGLTAVAEGMPSGAVVSG AARGEAVSAILFSGQGSQRAGMGKQLYGEFPVFADALDAVCAYLDKSLDRPIKDLMFAED GELLNQTQYTQASLFALEVALYRLVESWGIRPDFVTGHSIGELTAAHVAGVLSLEDAAAL VAARGRLMQALPTGGAMLSVQATENDIAPLLNGLEDKVSIAAINGPRSVVVAGDEEVIAE FEASWEWKTKRLKVSHAFHSPRMEPMLADFRKVAESLTFENPTIPVVSNVTGAVADVTDP DYWVRHVRHAVRFADGIQYLASQGVTTFLELGPDGVLTGMAQDTAPEATHIPALRRDRDE AHTLTTAIAKLHTTGVSVDWQAFFAGTGARTVDLPTYPFQRERYWLESVGGVGDVSSAGL ESADHPLLGAAVELPDGDGVVFTGRVSLATHPWLSGHALGGTVLVPGTALVELAIRAGDQ VGSGAVDDLILETPLVLPEQGSVLLRLVVGDADETGRRTFTVHSRPAGSGAGQWVRHASG ALTEAGTSPVAEHETWPPEGAEVVPTEQMYTDLAASGFCYGPAFQGLRTVWQRDGEVFAE VALPPEFHAEAARFEIHPALLDAALHPLGLGTLTTAESGAGPALPFAWSGVSLYATGATE LRVKLSPTESGGVSVAVADSAGAPVASIESLSLRSVSADQLGSAAGPDSLFGVDWTTVAL PEGAATTSVAALGTALGLDVPVHATLAELGTEPEFVLAELPAQSEVDARAVRDAVLGTLE LVRSWLAEDRFSGSRLVVVTTGAVSTGEAVTDLAGAASWGLVRSAQSENPGRIVLVDVDG TEESSAALLAALALDEPQLAIRGGVAFAPRLATTAAGLVPPPGEQPWRLEVTTPGTVDNL ALVPFGSAAEPLAPHEVRIAVRATGVNFRDVLITLGMYPGEAVMGTEAAGVVVETGSEVR TVEQGDAVMGIVESGYAPVVVADSRTVARIPAGWSFEQAASAPAVFLTAYYGLVDLAGLH SGQSVLVHAAAGGVGMAAVQLARHLGAEVFATASPAKWESLRNRGIDEAHTASSRDAGFE GKFTPVDIVVNSLTGELTDASLRLLKPDGVFVELGKADVRDPAKVAADHDGARYRSFDLG DPGPERLRDMLSELLGLFEAGVLEPLPVRAWDVRRAPEAFRFISQAKHVGKVVLTMPRAL DPDGTVLVTGGTGALGAVLARHLVAERGVRRLVLTSRRGPAAPGADELVAELTDLGAAVD VVTCDAADREALASALAAIPEEHPLTGVVHTAGVVDDGVIASLTPERVEKVLRPKVDAAL NLHELTRGEDLALFAVYSSAAATFGAPGQGNYAAANAFLDALAQRRHADGLAGQSLAWGL WATEGGMTGELAEADLQRMSRGGVLPLTPEHGLALFDFASTMDEPLVVPIGLDTAGIAKA DPAAVPPLFRGLAKRPARRAIAGAAAPDTGALVRELGALSGDERHELLLGLVRTYAAAVL GFAGPEAVDPALAFSELGFDSLTAVEFRNQVGAATGLRLPATLVFDYPTPTALARQLDGE LGGDGDATGTPVLSELDRLEAALAKAELDSTTGTQVKSRLQAILSRWSDQDEVGDVTAVA QNLEGATPDEVFDFIDKELGIS NT seq 16989 nt NT seq  +upstreamnt  +downstreamnt atgtcgggtgaggagaagtttctcgagtacctcaagcgggtcacggcggatctacgggag acccgccagcggctgcgcgaggtggaggaacaggcgagcgaaccgctcgccgtcatcggc atgagctgccgcctgcccggtggggtgcgcacgcccgaagggctttggcggctgctggcc gacggcggggacgcgatctcggggttccccgccgaccgcggctgggacctggacggcctc ttcgacgccgatcccgacgccgagggcaccagctacacgcggcagggcgggttcatccac gacgccgcggacttcgacccggtgttcttcgggatctccccgcgcgaagcgctcgcgatg gacccccagcagcggctgttgctggaaggggcttgggaaacgttcgaacgggccgggatc gacccgtccacgttgcgcggcagcaagcacggcgtgttcgtcggtgcctacggccagggc tacggcaacgcgctcggctactccggcgaaagcatcgagggctacgtcgccaccggaacc gcgggcagcatcatctccgggcgcgtcgcctaccagctcgggctggagggcccggcggtc acggtggacaccgcgtgctcgtcgtcgctggtggcgctgcacctcgccgggcaggcactg cgcacgggcgagtgctcgatggcgctcgtcgcgggcgcggccgtgatggctgtcccgacc gggttcaccgagttcagccgccagcgcgggctcgccgccgacggccgctgcaaaccgttc tcggaatccgcggacggcacgagctggggtgaggccgtcggcctgatcctggtcgaacgc ctttccgaggcaaggaagaacgggcacgaggtgctcgccgtcgtccggggttccgcggtc aaccaggacggcgtcagcaacgggctgaccgcgccgaacgggcgcgcgcagcagcgggtc atccgcgaggcgctcaagaacgccgggctttccgccgcggaggtcgacgcggtcgaggcg cacggaaccgggaccaccctcggcgacccgatcgaggcgcaggccctgctggcgacctac ggccagggcaggccggaggggcagccgctgtggctgggctcggtcaagtcgaacttcggg cacacccaggccgcggccggggtggtcggcgtgatcaagatgatcctcgcgatgcgcgag ggcgtgctcccgaagacccttcacctggacgagccgagccaccgcgtcgactgggactcc ggtgcggtgtcgctgctgaccgagcagaccccgtggcccgtcaccgggcgcccgcgccgc gcgggcgtttcgtcgttcgggttcagcggcacgaactcccacgtcatcctcgaacagccc gagccggtcgaagccgaggcgatcgaacggggtgcggccccggtcgcgctgccctggctc gtttcgggtaagaccgccgacggcctgcgcgcgcaggcggcgaatctgcggtcccatgtg gacggcgatctggtcgatgtcgccttctcgctggcgaccacgcgtgccgcgctggagaac agggcggtcgtgatcggccgcgaccgcgacgacttcctgtccgccttgaacaccctcgcc gaggaagacgccaccagcaccgcggtgcggggtgtggcggatgtgcggggcaaggtcgtg ttcgtgttcccgggtcagggttcgcagtggatcggcatggcggtggatctactggggacc tccccggttttcgcggagcggttcgcggagtgtgagcgggcgttgtcgtcctttgtggac tggtcgctaaccgaggtggtcggtgacgaggccgcgttggaacgggtcgacgtggtgcag ccggtgttgtgggctgtgatggtgtcgttggccgcggtgtggcgttcctatggtgtggag cccgctgcggtggtcggtcactcgcagggtgagatcgccgccgcggtggtcgcgggcgca ctgtcccttgaggacggtgcacgggtcgtcgcgctgcggagccaggcgattcgggacgag ctggccggtaagggcggcatggtttccgtcgcccagccggagagtgctgttgctgagagg atttcccgtttcggtgaccgggtcgcggtggccgcggtcaacggacccggcaccacggtc atcgccggtgagcccgatgcgctggccgagattctggctgagtgcgaggcggaagaggtc cgggcgcgcaggatcgccgtggactacgcgtcgcacacgccgcaggtggagtccattcgc gaccgtctcttggaggtgctggcgccgatccagccccgcgccgccgaggtcgcgttcttc tccaccctcaccgccgactggcaggacaccaccgggctcgacgcccgctactgggtggag aacctgcgccacaccgtcaagttcgaacaagcaacccgggcgctcgctgagcagggttac cggttcttcgtcgaatccagcgcgcaccccgtgctgaccatgagcgtgcaggaaaccctc gacaccaccgacgacgccgacggcgtcgcgatcggttccctgcgccgcgacgaaggcggc ctcgcgcgattcctgacctccctggcagaaggctacgtccgcggcctcgccgtcgactgg acgcccgcgttcccggcgggcgcgcgccgggtggacctgccgacgtacgcgttccagcgg caaagcctgtggccgaaggcgaacccggcactggtcgcgggcgacgtcagctccgtcggg cagggctccgccgaccacccgctgctcggcgcggtcgtcgcgatcgccgacggcgacggc cacctgctgaccgggcggctgtccgtgcagacccacccctggctcgccgaccacgccgtc ggcggcacgattctgttgcccggcaccgcgttcgtcgaactggccatccgcgccggcgac caggccgggtgcgatctcgtcgaagagctgaccatcgaagcgccgctcgtgctgcccgaa cgcggcggcgtgcagatccagctgatcgtctccgcaccggacgagaccggccgccgcgcg ctgaccctccattcgcgaccggaggacgcggaccagccgtggacgcggcacgcgagcggg tcgctcggcaccgggcacgtcgaccacgccgacctgaccgcgtggccgccgcccggcgcc gaggagatcgacggcgtccgcgacggcatgtacgaccggatggccgagcgcggctacggc tacggccccgccttccagggcctgcgcgccgcatggcgccgcgacggcgacgtgttcgcc gaggtcaccctgcccgacgagcagcgcgccgacgcacccggtttcggcctgcaccccgca ctgctcgacgcggcactgcacgcgatcgggatcggtggcctgctcgccgacccggacgaa gtgaagctcccgttcgcctggagcgacgtttccctggcagccacaggcgcgtcgagcctg cgtgtccacctttcgcccagcggcaccgacgcggtctcactccggctcgcggacgccacc ggcgctccggtcgcgtcgatcggttccctcgtcctgcgcccgctgtcgacgggacagctc ggctcggcgcggtcggccggtgccgactcgctgttccgggtggactggaccgagcttccg ctcccggacccggtcgtggacatcgccgcgctcggcgcggacgcactgggcatcgccgga gcggggacctacgccgatctcaccgcactggccgaggccatcgagcacggcgccgcggtt ccgggcgccgtgctcaccgaactgcccgaagtgtcctctgtggacgcggtgggcgtgcgt acttcgacgaacctggttctcgacctgatgcagcgctggctcgccgaggaccggttcgcc gactcgaagctggtgctgctcaccaagggcgcggtgctgggcgacggcgcgaccgacctg gtcgccgccccggcgtggggactggtgcgctcggcgcagtccgagaaccccggccggttc gtactggccgatgtagacgacaccgccggtgccgcgctggccgccgcgctcgccaccgac gagccgcagctcgcgctcaggaacggaaccctttacgtaccaaggctcgcacgtgccgcc gccgggagcgccctcgcgccgtcggcgccggtgtggcggctggactccaccgcgaccggc acgctcgacacgctcgcgctggtggacaactcagaggcactgcggcccctcgccgccggt gaggtccgcgtcgaggtgcgcgcgggcggggtcaacttccgcgacgtgctgatcgcgctc ggcatgtaccccggtgacgcgaacatgggcagcgaagcggccggtgtcgtcgtcgaaacc gggtccgaggtcaccgatctcgcggtcggcgatcgcgtgttcggcgtgttccaccacggt ttcgcaccggtggccgtcgccgaccggcggatcatcgctccgatccccgaaggctggtcg ttcgagcaggccgcgaccaccccgatcgtgttcctcaccgcgtactacgggctcacccgg ctggccgggctgcgcgccggggaaaccgtgctggtgcacgcgggcgcgggcggggtcggc atggccgcgattgcgctcgcccgccacctcggcgcggaggtcttcgccaccgccagcccg ggaaagtgggacgtgctgcgctcgctcggcgtcgacgacgagcacctcgcctcgtcccgt gatctcgatttcgaagccaagttccgcgccgccaccggtgaccgcgggatcgacgtcgta ctcgactccctcgccggggagttcgtcgacgcctcgctgcggctgaccgcgcccggcggc cggttcgtcgaaatgggcaagaccgacgtgcgcgaccccgcgcgggtggctgccgagcac gaggtttcctaccaggcgttcgaactgttccaagcgggcgaggacgcgctcggccgcatg ctggccgaactactcgacctgttcggccgcggtgtgctgcgcccgctgccggtcaccacc tgggacgtgcgccgcgcgaaggacgccttccgccacctgagccaggccaagcacgtcggc aaggtcgcgctggtgatgccgcgcgcgctggcgtccgagggcacggtgctcgtcaccggc ggcaccgggctgctcggcggcctgctggccaggcacctggtgaccgagcacggcgtgcgg cacctgctgctcaccagccgccgcggcgaagcggccgagggcgccgcagaactccgggcg gaactgaccgctctcggcgccaccgtcaccatcgccgcgtgcgacgccgccgaccgcgcc gcgctcgcgaacctgctcgcgaccatccccgccgaacacccgctcaccggtgtggtgcac accgcgggtgtgctcgacgacgccacgatcacctcgctgaccccggagcggctcgacgcc gtgctccggccgaaggtcgacgccgcgctcaacctgcacgagctgaccgaggacctcgac ctcgccgcgttcgtgctgttctcctccgccgcggccaccttcggcagccctgggcaggga aactacgcggcggcgaacgcgttcctcgacgcgctcgcccaccggcgccgtgccgaaggc cgtgcggcgcagtcgctcgcctggggcctgtggcagcagcgcagcgggatgaccgggcac ctcggcggttcccgtggcagcgagctgagcaccgaacacggactcgccctgttcgacctc tcgtccacaatggacgaaccggtgctggtgccgataccgctcgacctccgcgcgctctcg gcgggaccggtgcccgcgttcctgcgcggcctggtttcctcgccgcaccgcagggccgcg gcgaacagcgctgagacggatctgaccggtctcgccgggcgcctcgccggactgtccgaa cgggaccaggaagaggcgctgctcgaactcctgcgcgccaacgcggccgcggtgctcggg ctcccgcccaacgtcgtcgaggcggcgaaaccgttccgggacatcgggttcgactcgctc accgcggtcgaactccgcaaccggctggccaccgccaccggcacacgactgcccgccaca ctcgtcttcgactacccgacgcccacggtgctcgccaagcacctgcgcaccgaactgctc ggcgcggacctgccggtcaccaccggcaccgcggcgggcgcggccaccgacggcgagccg atcgcgatcgtcgcgatgagctgccggttccccggtggcgcccactcacccgaccggctg tggcagctggtcaccgagggcggcgacgcggtgtccgcgttcccgcccgatcgcggctgg ttcgccgagggcgccgggtcggagttcaccggcgcgggtggtttcgtttacgacgccgac cggttcgacgccgggttcttcggcatttccccgcgcgaggcactggccatggacccgcag cagcgcctgctgctggagtcctcgtgggaggtgctcgaacgcgccgggatcgacccggaa tcgttgcgcggcacgcaaaccggcgtgttcgccggagccgcccacaacgggtacgccacc gggatccacgagatgccggaaggcatcgagggctacctgatgaccggcaccaccggcagc gtggtgtcgggccgggtcgcctacaccttcggactggagggcccggcggtcacggtggac accgcgtgctcgtcgtcgctggtggcgctgcacctggcctgccagtcgctgcgcgcgggg gagtgctcgatggcgctcgccggcggggtgaccgtgctgtccacgccggggctgttcgcc gagatcgggaagcagggcgggctcgccccggacggccggtcgaaggcgttctccgaggac gcggacgggatgggcgccgcggaaggcgtcggcatgctgctcgtggagcggctttcggac gcccagcgcaacgggcacccgatcctggccgtggtgcggggttccgcgatcaaccaggac ggcgcttcgaacgggttgacggcgccgaacggtccgtcgcagcagcgggtgatccggcag gccctcgccaacgcgaggcttgaagcgtccgatgtggacgctgtggaagcgcacggcacc ggcaccgcgctcggcgacccgatcgaggcgcaggcactgcaggcgacctacgggcgcgac cgcgagcgcccgctgtggctgggctcgctcaagtcgaacatcgggcacaccacggccgcg gccggggtggccggggtgatcaagatggtgcaggcgctgcggcacggagtgttgccgaag accctgcacgtcgaacggcccacctcgcacgtcgactggtcggcgagcgccgtgaccctg ctgaccgaggagatcggctggccggaaaccggggcaccgcgtcgtgccggggtgtcgtcg ttcgggatcagcggcaccaacgcgcacgcgatcctggaacaggcgcccgcgaccgaggaa gcacccggtccggtcgaagcacccgcggtgctgccgtgggtcctttcggcgaagaccggc ggcgcgctccccgcgcaggccgccaccttgaagtcctatctggacacccgccccgacctg gcgccggtggacgtgggcttctcgctcgtgtcctcgcgggcggcactggaccaccgcgcc gtggtcatcggtgatcccgccgccctgctggcggggctggatgccatggctggcgggggt tccgccgcgcagctcgtgaccggcgtcgccgatgtgcggggcaaggtcgtgttcgtgttc cctggtcagggttcgcagtgggtcggcatggcggtggacctgctgtcgtccagtgcggtg ttcgcttcccggtttgccgagtgtgagcgggcgttgtcgtcctttgtggactggtcgttg accgaggtggtcggtgacgaggccgcgttggagcgggtggatgtggtgcagccggtgttg tgggctgtgatggtgtcgttggccgcggtgtggcgttccgttggtgtggagcctgctgcg gtggtgggtcattcgcagggggagatcgcggcggcggtggtcgcgggtgcgttgtctctt gaggacggtgcgcgtgtggtggcgttgcggagtcaggcgattcgggatgagctggcgggt aagggcggcatggtttccgtcgctcagccggagagcgctgtggtggagcggattgctcgg tttggtgatcgggtggcggtggctgcggtcaacggtcccggaaccacggtgatcgccggt gaacccgaggcgctggccgagattctggctgagtgcgaggcggaggaggtgcgggcgcgg aagatcgcggtggattatgcgtcgcacactccgcaggtggagtccatccgcgaccgcctg ctggacgttctgtccccgatccagccgcgcggtacggagatcgggttcttctcgaccctg accggtgactggcaggacaccaccgggctggatgctcgttattgggtggagaacctgcgt catacggtgaagttcgagcagacgactcgggccctgtccgagcagggctacgggttcttc gtcgagtccagtgcgcatccggtgctgacgatgagcgtgcaggaaactctcgacaccctg gaaaccgagggcgtcgcggtcgggaccctgcgccgcaacgaaggcggtgtggatcgcttc ctgatctcgcttgcagaggggtatgtgcgtggtctccgggtggactgggcaccggtgttc ccgtcgggtgcgcgccgggtggagctgccgacctacgcgttccagcgtcagcggttctgg ctggaatcaacggcttccgccagcgggctgatgaccacggatgtggtggaggcgcggttc tgggatgcggtggagaacgaggacttggaggccttggctgggacgtgggagatcgatggt gatcgcccgttcagcgaggtgttgccggtgttgtcgtcgtggcggcggcagcgtcgtcag cagtccacagtggaccagtggcggtacggcgtcacctggaagccgctgaccaccgcagcc gcgcggttgtccggcacctggctgctgatcaccgagtccgaagaggccgcttggttcgcc gacgccctgcgtgcgcacggcgcggacgtggtcaccgttgaggcgggtgagctgtctgcg cgaatcaccgaactcggtgagatcgcgggtgcggtctccctggcttccggtgcggcggag acgctggtggtggtgcaggcgctgctggacagcacggtggcggcaccggtgtggatcgcc acccggggtgcggtgtcagtgggtcgctcggaccgggctgccgaccctgagctggcccag atttggggtctgggccggattctgggtctggagcacccggaccggtggggtggtctgctg gaccttcccgccagcagcgatagccgtgcggctgcgcgggtcgtggctgtgctggcgggg atcggggatgaggatcaggtcgcggtgcgtgattccggggtgttcgcgcggcgtcttacg cggtcgccgttggcggagcgggagccggtgcgggagtggtcgccgcgcggcacggtcctg gtcaccggcggcaccggtgcgctgggtgggcatgtggcccgttggctggccgcgaacggt gccgagcacctcgtgttgacctcgcgccgtggccgggacgctgatggtgcggtggagttg gaaaccgagttgtccgggctgggtgcgcgggtcacgatcgtggcctgtgacgctgctgat cgcgatgccttggcggtggtgctggctgagcatggtccgttcagtgcggtggtgcacgcg gcgggagtgggggagttcgcgcccctgaccgacaccacgatcgaggacctgtcccgcatc atcagcgcgaaggtggatggcgcccgcaatctggacgagttgctcggggatgccgagttg gatgcgttcgtgttgttctcctccaacgccggtgtctggggtggcggcacccagggcgcc tacgcggcgggcaatgcgttcttggacgcgttggccgagcagcgtcgcgctcgcgaggtg accgcgacttcgatcgcgtggggcgcgtggggtggcagtggtcttgccgcgtcggatgca gctgaggacaccctgcgccgtcgtggtgtgttgccgatggcacccgaagccgccgtcgcc gcgctcgtccaatcagttgagcacgatgagactttcgtggcagtggctgatgtggactgg gcgcggttcgtgcccgggttcaccgccgcccgcccgcgtccgttgatctccgacatcccc gaagcacgccacgccctcgacagcgccggagaggaaaccggcgccgacagctcggcactg gccgagaagctcgccggactgtccgaagtggaacgccagcgcgcggtgctcgacgtggtg cgcgcggaagcggcggcggtgctcggctacgcctccgccgaggaggtcgagcgcggccgg gcgttccgggacatgggcttcgactcgctgaccgcggtggaactgcgcaaccggctgtcc accgcgaccggactcaaactgccgaccacgctcgtcttcgactacccgaactccgttgtg ctgtcggagttcctggtccgggaagtgaccggtgcgcggcagggcgttgccaccgcgtcg accgtgtccgccgccgccgacgagccgatcgccatcgtcggcatgagctgccgctacccg ggcggggtcaactccccggaggagctgtggcagctcgtcgagaacggcggagacgccctt tcggcgcttcccggcgaccgtggttggaaccttccggagctgctcggctccgatctcgcc gacagtatcgagggcggattcctctacgacgtcggcgagttcgatgcggcgttgttcggt atttcgccgcgtgaggccctcgccatggatcctcagcagcggttgttgctggaggcgtcg tgggaggtgtgcgagcgggcggggatcgatccgagttcgttgcggggcaccaggaccggg gtgttcgcgggcgcctccaactcggcgtacggcttcgggctcgggcaactccccgacggc gtcgagggctacatgctcaccggaagctccggcagcgtggtgtcgggccgggtttcctac accctcgggttggagggccccgccgtcacggtggacaccgcgtgctcgtcctcgctggtg gccctgcacctcgcctgccaggcgttgcgggccggtgagtgctcgctcgcgctggccggt ggcgtcgcggtcatggtcgttcccggtgcgttcgcggagttcggccgccagggcgggctc gcggcggacggccgctgcaagtcgttcgccgaggccgcagacggcaccgggtggggcgaa ggcgtcggcatgctcttggtggagcggttgtccgacgctcgccgcaacgggcacgaagtg ctggcggtggtgcgtggttccgccatcaaccaggatggtgcgtcgaacgggttgacggcg ccgaacggtccttcgcagcagcgggtgatccgtgacgcgctggcgaacgccggactgact ccgtccgatgtggacgcggtggaggcgcacggtaccgggacggtgctgggtgatccgatc gaggcacaggcgctgctcgcgacctacggccaggaacgggaacgcccgctcttcctcggg tccgtgaagtcgaacatcgcgcacacccaggccgcctccggggtcgccggtgtgatcaag atggtcctcgccatgcggaacggggtgttgccgaagacgttgcacgtggacgagccgtcg tcgcatgtggactggtcggcgggtgcggtttcgctgctgacggagaacgccgagtggccg gagacgggggcgccgcggcgtgcgggtgtgtcgtcgttcggggtgagcgggacgaacgcg cacacgatcgtggagcaggcgccgaaggtcgaggaaccggtggtcgtggaccactccccg gcgaaccggccgctgccttgggcgctttcgggcaagagccaggacgcggtacgcgcacag gctgcccgactcctgtcccatgtggacggactgaacgaagccgatgtcgcttactccctg gccaccaccagggcgagcctggaccaccgcgccgtggtggtcggtgcggatcacgacgag ttcgtggccgggctgacggcggttgccgagggcatgccgtcgggtgctgtggtgtccggg gctgcgcgtggtgaagcggtttccgccatcttgttctctggtcagggttcgcagcgtgcg gggatgggtaagcagttatatggggagttccccgttttcgcggatgccctggatgcggtg tgcgcgtatctggacaagtccctggatcgtccgatcaaggacctgatgttcgccgaggac ggcgagctgctcaaccaaacccagtacacgcaagcctccctgttcgcactcgaagtcgcg ctctaccggctggtcgagtcctggggcatccgcccggacttcgtcaccgggcattcgata ggtgagctgaccgcggcccacgtcgcgggtgtgctgtcccttgaggacgcggccgcgctg gtggccgcgcggggccggttgatgcaggctctccccaccggtggggcgatgctttccgtg caggcgaccgagaacgacatcgcgcctctgctgaacgggctcgaagacaaggtgtcgatc gccgcgatcaacgggccgaggtcggtcgtggtcgccggtgacgaagaagtgatcgccgag ttcgaagcgtcctgggagtggaagaccaagcggctcaaggtcagtcacgcgttccactcg ccacggatggagccgatgctcgcggacttccgcaaggtcgccgagagtctgaccttcgaa aatccgacgattccggtggtgtccaatgtgaccggtgcggtggcggatgtgaccgatccg gactactgggtccgccacgtccggcacgcggtccgcttcgccgacggcatccagtacctg gcaagccagggcgtgaccacgttcctggagctgggcccggacggcgtgctcaccgggatg gcccaggacaccgcacccgaggccacccacattcccgcgctccgccgcgaccgcgacgaa gcacacacgctcaccaccgccatcgcgaaactccacaccaccggagtttccgtcgactgg caagcgttcttcgccggaaccggcgcccgaaccgtggacctccccacttacccgttccag cgcgagcggtactggctggaatcggtcggcggtgtcggggacgtgtcctcggccgggctc gaatcggcggaccacccgctgctgggtgcggcggtcgagctgccggacggcgacggcgtg gtattcaccggccgggtctccctggccacgcacccgtggctgtccgggcacgcgctcggc ggcaccgtcctcgtcccgggcaccgcactggtggaactcgcgatcagggccggtgaccag gtcggcagcggcgccgtcgacgacctgatcctcgaaacaccgctcgtgctgcccgaacag ggctcggtgctgctgcggctggtggtcggcgacgccgacgagaccggccgccggacgttc accgtgcactcccgtccggccggatccggtgcggggcagtgggtccggcacgccagcggc gcgctcaccgaagcggggacatccccggttgcggagcacgagacctggccgccggagggc gccgaggtggtgcccaccgagcagatgtacaccgatctcgccgcctccgggttctgctac ggaccggcgttccagggcctgcgcacggtgtggcagcgcgacggcgaagtgttcgccgag gtcgccctgccaccggagttccacgccgaggcggcccgcttcgagatccaccccgcgctc ctcgacgccgcgctgcacccgctcggcctcggcaccctgaccacggccgagtccggtgcc gggcccgcgctgccgttcgcgtggagcggggtctccctctacgcgaccggggccaccgaa ctgcgggtgaagctgtccccgacggaatcgggcggcgtttcggtcgcggtcgcggactcg gccggtgcaccggtcgcgtcgatcgaatcgctgtctctgcggtccgtttcggctgaccag ctcggatccgcggccggtccggactcgttgttcggcgtggactggacgacggtcgcgctc cccgaaggagcggccacgacttcggtcgcggcgctcggcacggcactcgggctcgacgtg ccggtccatgcgacgctggcagaactgggcaccgagccggaattcgtgctcgccgaactc cccgcacagtccgaagtggacgcacgtgcggtgcgcgacgcggtgctcggcaccttggaa ctggtgcggtcctggctcgccgaagaccggttcagcggttcccgcctggtcgtggtgacc accggcgcggtgtccacgggtgaggcggtcaccgatctcgccggtgcggcgtcgtggggc ctggtgcgctcggcacagtcggaaaaccccggccgcatcgtcctcgtcgatgtcgacggc accgaagagtcgtccgccgcactgctcgccgcgctggcgctcgacgagccgcagctcgcg atccgtggcggggtggccttcgcaccgaggctggccacgacggccgccgggctggtgccg cccccgggcgagcagccgtggcggctcgaggtgaccacgcccggcaccgtcgacaacctg gcgctcgtgccgttcggatcggcggcggaaccccttgccccgcacgaggtccggatcgcg gtgcgcgccaccggcgtcaacttccgcgacgtgctgatcaccctgggcatgtacccgggc gaagcggtgatgggcaccgaggcggccggtgtggtcgtcgaaaccggatccgaggtgcgc accgtcgagcagggtgatgcggtgatgggcatcgtcgagtccggctacgcccccgtggtg gtggccgattcccgtaccgtggcgcggatcccggccggatggtcgttcgagcaggccgcg tccgcgcccgcggtgttcctgaccgcctactacggcctggtcgatctcgccggactccac agtggccagtcggtgctggtgcacgcggccgcgggcggggtcgggatggccgcggtgcaa ctcgcccgtcacctcggcgccgaggtgttcgcgacggccagccccgccaagtgggagtcg ttgcggaacaggggaatcgacgaagcgcacacggcttcctcgcgcgacgccgggttcgaa gggaagttcaccccggtcgacatcgtggtgaactcgctgaccggcgagctgaccgacgcc tcgctgcgcctgctcaagccggacggggtgttcgtcgaactcggcaaggccgacgtccgc gatccggcgaaggtcgccgccgaccacgacggcgcgcggtaccggtcattcgacctcggc gaccccggcccggagcggctgcgggacatgctctcggagctgctgggcctgttcgaagcc ggtgtgctggagccgttgccggtgcgggcctgggatgtgcggcgggcgccggaggcgttc cggttcatcagccaggccaagcacgtcggcaaggtcgtgttgacgatgccgcgggcgctg gacccggatggcaccgttctggtgaccggcggcaccggggcgttgggtgcggtgctggcg cggcatttggtggccgagcgcggggtgcggcggctggtgctgacgagtcgtcgtggtccg gcggcgccgggcgcggacgaactggtcgcggagttgacggacttgggtgccgctgtcgac gtggtgacatgcgatgccgccgatcgggaggcgctggcgtcggcattggcggctattccg gaggagcatccgctgaccggtgtcgtgcacaccgcgggcgtggtcgacgacggagtgatc gcgtcgctgaccccggaacgggtcgaaaaggtgttgcggcccaaggtggacgcggcgctc aacctgcacgaactgacccggggcgaagacctcgcgttgttcgcggtgtattcgtcggcc gcagcaacgttcggggcgccggggcagggtaactacgcggcggcgaacgcgttcctggac gcgttggcgcagcgccgtcacgccgacggcctcgccgggcaatcgctggcgtggggcctg tgggccaccgagggcgggatgaccggcgaactcgccgaagccgatctccagcggatgagc cggggtggcgtgctgccgctcaccccggaacacggcctcgccctgttcgacttcgcgtcc acaatggacgagccgctggtggtgccgatcggactcgacaccgccgggatcgcgaaggcc gatcccgccgcggtcccgccgctgttccgcgggctggccaagcgcccggcccggcgggcg atcgcgggcgcggcggcacccgacaccggcgcgctggtgcgggagctgggcgcgctgtcc ggcgacgaacggcacgaactgctgctcggcctcgtgcggacctacgccgcggcggtgctc ggcttcgccgggccggaggcggtcgacccggcgctggcgttctccgagctgggcttcgat tcgctgaccgcggtggagttccgaaaccaggtcggcgcggcgacggggttgcggttgccc gcgacgctggtgttcgactacccgacccccaccgcgctggccaggcagctcgacggcgaa ctgggcggggacggggacgccaccggtaccccggttctgtccgaattggaccggctcgaa gccgcgctggccaaggcggaactcgacagcacgacgggcacgcaggtgaaatcccgcctg caggccatcttgtcccgatggagtgaccaggacgaagtaggggacgtcaccgccgttgct cagaacctcgaaggagcgacacccgacgaggtgttcgacttcatcgacaaagagctcggc atctcctga

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