Amycolatopsis sp. CA-230715: HUW46_01947 Help Entry HUW46_01947       CDS       T10444                                  Name (GenBank) hypothetical protein   KO K16386   polyene macrolide polyketide synthase Organism amyz  Amycolatopsis sp. CA-230715 Pathway amyz01052   Type I polyketide structures Brite Polyketide biosynthesis proteins [BR:amyz01008]  Polyketide synthase (PKS)   Modular type I PKS    cis-AT PKS     Polyene macrolide PKS      HUW46_01947 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Other DBs NCBI-ProteinID:  QWF78551 UniProt:  A0A975RDJ1 LinkDB All DBs Position complement(2156249..2172484) Genome browser AA seq 5411 aa AA seqDB search MANDDKVIEHLKWMTAELRRSRRRVQELEEAAQEPIAIVSMACRYPGGVNSPEDLWRLVA SGEDATSGFPVNRGWDLDRLFDDDMDRLDTSYVRTGGFLHDADQFDPAFFGISPREAMAM DPQQRLLLQTAWEALERAGIDPTSLKGSRTGVFAGLGRGEYGTGWAEIPDDLAPYVGNGS ATSVASGRISYILGLEGPAVTVDTACSSSLVALHLAVQALRQGDCSLALAGGATVMSTPD LFVDLCRQRVLSKDGRCKSFADAADGAGWSEGAGLLLVERLSDAQRNGHDVLAVVRGSAV NQDGASNGLTAPNGPSQQRVIRQALASARLSAGEVDVVEAHGTGTRLGDPIEAQALMATY GQGRPEGEPLWLGAIKSNIGHTQGAAGVAGIIKMVMALRHGVLPKTLHVDAPSSEVDWTE GEVRLLTEGMAWPERDRPRRAGVSSFGISGTNAHTILEQAPEVEKSPVADFDGVLPWVVS GKTPEARQAQAERLRTYVEGIEDLRHADIGHSLATTRAALEHRGVVVGGNREEFLTGLEL LARGETGPGVAQAAADAEGKIVFVFPGQGSQWVGMGRELLETNAVFAAKFAECERATSSF VDFSLTEALDDEDALARLDVVQPVLWAVMVSLAAVWRSYGVHPSAVVGHSQGEIAAACVA GGLSLEDGARVVALRSKALLEELFDKGELASVALPADQVAERLTEFDGRVAVAAINGPTS TIIAGDTEPLARVFDEWEAAGVRVRRVPASCPSHTQHVEVLRERMRTELGPIRPREGEVA FFSTATGTWQDTAGLDADYWFENMRQVVRFADATKSLFGQGYRFFVEASAHPVLAVSVQE NVESLDGASAAVVGTLRRNEGGLARFFTSLGQLFAEGVTPDWSAVFGEGAQRVELPTYVF QNERYWHSSTTAAGDVTSVGLTSAEHPLLGAGVDLPDTDGFLFTGRLSLQTHPWLADHAV ADTVLVPGTAFVELAIRAGDQVGCQTVEELTLHAPVILAAQGAVRLQVVVGAPDETGRRS LTVHSRAEDAPSNSAWTRNASGFLAEAEPVGGFDLAAWPPPQAEPVEDATGLYGRLTELG YQYGPAFQGLKAAWTRGDEVFAEVALPEEHHADAAGFGVHPALLDAALHACSFGALVKGD EGMGLPFAWTGVSLSAAGATTVRVRITPAGSDGISVQVADQTGAPVVSVEAMVLRPVSAE QLAAARDTGPDALYQLDWTVVEPPRDAGTEGWVVLGEDRFGLGDFLTYPDLAALIAAVDD GAPVPEVVIAPETVPLSGNPADAARTAAAKALGLAQTWLADDRFDAARLVLVTSGAVAVD AESDVTDLASASAWGLLRSAESENPGRFVLADLDGHADSPRALVAALTTDEQQLAVREGI VRAPRLARAGTGSLTIPADTRAWRLEVSEQGTLANLALRECPEALDALEPGQIRISVRAA GMNFRDVVVALGMVPGQDIMGSEIAGVVTEVGEGVTDLQPGSKVFGIVDRAFGPLAVAYR ETVTPIPDGWTFEQAASTPIVFLTAYYGLIDLGGLRAGESVLVHSAAGGVGMAAVQLAQH FGAEVFGTASAGKWDALRSMGLDDEHIASSRDLGFEQAFGGVDVVLNSLTQDFVDASLRL LSDGGRFLEMGKTDKRDPDEVAAAHPGVRYRAFDLIGASADRLQEMLRELVVLFEQGALK PLPVRTYDVRRAPDAFRFLSQAKHIGKLALTMPRELDRDGTVLITGGTGTLGGLAARRMI TEHGIRHLLLTSRRGPDAPGAAELAAELTDLGAEVRIVACDVADFAATEALLSSIPAEHP LTGVLHTAAALDDGVVSSLTRERVDAVMRPKADAAWNLHELTKDLDLALFVLYSSAASVF GASGQGNYAAANAFLDALAQHRRAAGLPAQSLAWAMWEQRSELTRHLGDDQMRKRSNDGF PPLTSEQGMALLDVAAGVDEAMLVPIQIDTDVVRRKISGAVPPLLRGLIRATPRRVVEAG PTVTGMAGRLSGLSEGEQHALVLAVVRSNVASVLGHASAESIGADRAFKELGFDSLTAVE LRNRLATATGVRLPATAVFDHPSPAELAEFVRSELLGVKLEETAPVVSAHPATDDDPIVI VGMGCRFPGGVASPDDLWRLVDSGTDAISEFPTDRGWDLDGIYDPDPDVPNTTYSTEGGF IYDIAGFDADFFGISPREALAMDPQQRLLLETSWEALEQAGIDPSSLRGSRTGVFVGSYG MGYGWTLEDVPADLEGFLSSGQSTSIISGRVAYTLGLQGPAITVDAACASSLVALHWASQ ALAEQECSMALVAGVSVMVSPGAFTEFSRMRGLSKTGRSKAFAGAADGMGWGEGIGVLVV ERLSDARRNGHEVLAVVRGSAVNSDGASNGLTSPNGRAQQRVIRQALASANLTSAEVDMV EAHGTGTTLGDPIEAQALLATYGQDRPSDEPLWLGSLKSNIGHTQAAAGVAGIIKTVQAL RNGVLPKTLHVDEPTPHVDWSAGAVSVLDDARAWPDKGRPRRAGVSAFGLSGTNSHVILE HEPVPAEPSPEPAPVAGSVPWVLSGKTAEALRAQAARLRSHVDEHAELSPVDVAFSLATT RASLENRAVVFGGDRDEFLRGLAAVADGESVAGVVQGAAEAEGQTVFVFPGQGSQWTGMA VELLDTSEVFAERFAECERALSSFVDWSLSYAVRDEALLERVDVVQPALWAVMVSLAAVW RSYGVEPAAVVGHSQGEIAAACVAGALSLEDGARVVALRSIAISDELAGKGGMVSIALPE TAVVERIARFGDRVAVAAVNGPGVTVIAGEPEALAEILAECEEAEIRARKIAVDYASHTP QVESIRDRLLEVLSPIQPRAGEIAFFSTVTADWQDTTGLDAEYWVENLRRTVKFEQATRG LIEHGYRFFVESSAHPVLTIGVQETLEATGATGAVLGSLRRDEGGLDRFHTSLAEAYAAG AAVDWTAAFPEGARRVALPTYAFQHRNFWLAGEPVRPEAHTDEVEAVFWDAVEREDLEEL AATLDVADSSLGELLPALSSWRRQRREKSTVDNWRYRIRWQPVTGATEDARLSGTWLVVV ADGVEHEWVPAATAALAEAGARVAEVRLSADDRDRDDLARRLREAAGEEPVAGVLSLLGL DERPHPEHPVLTTGLTASVLLVQALAETGLGARLWFATTGAVSVGRSDSLTGLAQSPVWG LARSVGMEYAATWGGVVDLSVSSEGRATARLVSVLAGLDEDQVALRDSGVFACRLAHAPL RESAKTTEWRPRGTVLVTGGTGGLGAHAARWLAVHGAEHLVLTSRRGRAAEGAAELEAEL TGLGAQVTIASCDAADRDALADLLASLPGELTAVVHTAGVLADGVLSSMDLPRLAETMYP KVTAVWNLHELTRDLPLDAFVLYSSFSSTLGSAGQANYSAANAFVDAFAHYRRELGLPAT AIAWGAWAGSGLAVASDVRKDLLSGIGVPFMDPATAMLGFQQAVEADETHLAVIDIDWPV FMPALAEVRPRPLFDALPQARQALQPVAAAVAEAAGPPLAGRLAGLTGAERERELLDLVR GQVAVVLAHSSAEDVSRQRPFRDLGFDSLTALEFRNRIAAATGLSLPSTLIFDYPTPNAL CDFLLAELVGEDAAQAAQVELAAASTDEPIAIIGMSCRFPGGVGSPEDLWRLVDAGIDAM SAFPADRGWESETLYSDDPDSPGTTYATQGAFLDDAGGFDPAFFDISPREALVMDPQQRF LLEASWEAFERAGIDPTSVRGSRTGVFAGSNGQDYRYSIGDSAEDSEGYLMTGNAASVVS GRVSYTFGLEGPAVTVDTACSASLVALHLACQSLRQGECTMALASGVTVMTTPGGFVEFS RQRGLASDGRCKAFAAAADGTGWGEGVGVLLVERLSDARRNGHQVLAVVRGSAINQDGAS NGLTAPNGPSQQRVIRQALASARLAPSEVDAVEAHGTGTALGDPIEAQALLATYGQDRER PLWLGSVKSNIGHTQAAAGVAGVIKMVEAMRHGVLPRTLHVDEPTPHVDWTTGAVSLLTD TTPWPESGGPRRAGISSFGISGTNAHVIIEQAPPVPEVPERTPVHRVLPWPLAGKTEKAL RAQAARLLSTVDDFADLDVAYSLATSRAALEHRAVVVAADRDEFRRGLTALAEGDSVSTV VTGDAYGDTRSAVLFSGQGSQRAGMGKELYGEFPVFADALDAVCAELDRSLDRPLKELMF AEAGSEDAALLDQTQYTQVSLFALEVALYRLVESWGIRPDFVAGHSIGELTAAHVAGVLS LEDAAALVVARGRLMQALPSGGAMLSVQASEDEIAPLVVGLEDKVSIAAVNGPASVVIAG DEDVIAGFESAWEWKTKRLTVSHAFHSPHMEPMLAEFRAIARNLSFQAPKIPVVSTVPGG VGDVTDPEYWVRHVREAVRFADAVRRLEDQGVSAFLELGPDGVLTGMARDCLAGERVSLV TALRRDRDEVRTITAAVAGLHVRGVPVDWTALFAGTGARTVDLPTYAFQHQVFWPKYVPG ATAKGDAGSLGLASPDHPLLGAVVELAGEDGFLFTGRLSRPTLPWLGDDADGPDAAVPTV SSSVFLELAVRAGDQVGCGHLAELTLREPLVLPERGGVRLQVTVAAGDESGRRALEVFSR NDDEDGAWSCHASGVLAPAEPIAAAELAEWPPAKATPAPEEAFGAVRAVWTTEDALFAEI VLPEEHRDDAFALHPALLEALRPGRLIGDESLVPQTWQGFRLHAVGASSVRARISRAGSG AVSIDLADETGAPVATVASLTLREAPADRFGALRGGRNGSLYRVDWTEVPGRDWAPGAPL AVLGDAIDGVTGAESYVDLASLAAAVDAGAPSPEAVLVRVADPTGAVDATGIAAGVRQVT GRVLALLQQWLADDRFAASKLVLVTGGAVAAVPADSPNLVTAPVWGLVKAAQAEHPDRLA LVDVPGGAEWPRVLGAVFESGEHQLAVRDGALRAPRLVREQVTVDVDTGTAGAFDPEGTV LVTGATGGLGALFARHLVTEYGARHLVLASRSGRAAEGAAELEKDLAELGAEVSLVACDV ADRTALAGLLDGIGSAHPLTAVVHTAGVLDDGVTGALTPERLDTVLRPKVDAALNLHELT EDLKLSEFVLFSAAGSVLGAAGQGNYGAANTFLDALAQHRRARGMVGRALAWGLWAQTAG MAGELTAGQLARMDRGGVKPLSDEQGLALFDLAREAGEAALLPVRLDLTALRAELGGSVP PLLRGLLGDGTARPAAGKAAAQPDLSAELAGLSEAERRRAVLRLVRTQVATVLGHDDQSA VEVNRGFLEMGFDSLTAVDLRNRLTALTGRPLPATLLFDYPSPGELAEHLTAELGQVDGG DGGSLHADLERLERSVSAAAVDDGQRGEIATRLRALLAQLTPGSEEVSVADQLDAATDDE IFEFIDNNLDA NT seq 16236 nt NT seq  +upstreamnt  +downstreamnt atggccaacgacgacaaggtgatcgagcacctcaagtggatgactgccgagctccggcgg agtcgtcggcgcgtccaggaactcgaagaggccgcgcaggaacccatcgcgatcgtgtcg atggcgtgccgctacccgggcggcgtcaactcgccggaggacctgtggcgcctggtcgcc tccggtgaagacgccacctccgggttcccggtcaaccgcggctgggacctcgaccggctc ttcgacgacgacatggaccggctggacacctcctacgtgcgcacgggtggtttcctgcac gacgcggaccagttcgaccccgccttcttcgggatctccccgcgcgaagcgatggccatg gacccgcagcagcgcctgctgctgcagaccgcgtgggaagcgctggaacgggccggtatc gatcccacttcgttgaagggcagccgcactggcgtgttcgccgggctcggccgcggcgag tacggcaccggctgggcggagatcccggacgacctcgccccctacgtcggcaacggcagc gcgaccagcgtggcctccggccggatctcctacatcctcgggctcgaagggcccgcggtc accgtcgacaccgcgtgctcgtcgtcgctcgtcgcgctccacctcgcggtgcaggcgctg cggcagggcgactgctcgctcgcactcgccggcggcgcgaccgtgatgtccactccggac ctgttcgtcgacctgtgccgccagcgagtgctgtcgaaggacggccgctgcaagtccttc gcggacgccgccgacggcgcgggctggagcgagggcgccgggttgctgctcgtcgagcgg ctttccgacgcgcagcgcaacgggcacgacgtgctcgccgtggtccgcggctccgcggtg aaccaggacggcgcgtccaacggtctcaccgcgcccaacggcccgtcgcagcagcgcgtc atccgccaggcgctggcctccgcgcggctttccgccggtgaggtcgacgtcgtcgaggcg cacggcaccgggacgaggctcggcgacccgatcgaagcgcaggcgctgatggcgacctac ggccagggcaggccggagggcgagccgctgtggctcggcgcgatcaagtccaacatcggg cacacccagggcgcggcgggcgtcgcggggatcatcaagatggtcatggcgctgcggcac ggcgtgctgccgaagacgctgcacgtcgacgcgccttcgtccgaagtggactggacggag ggtgaggtccggctgctgaccgagggcatggcctggccggagcgcgaccggccccggcgc gccggggtgtcctcgttcgggatcagcgggacgaacgcgcacaccatcctggaacaggca cccgaagtggaaaagtccccggttgcggacttcgacggcgtgctgccgtgggtggtgtcg ggcaagacccccgaggcacggcaggcgcaggcggagcggctgcggacctacgtcgagggc atcgaggacctgcggcacgccgacatcggccactcgctcgccacgacgcgggcggcgctg gagcaccgaggcgtcgtggtcggcggcaaccgcgaggagttcctgaccggcctggaactc ctcgcacgcggtgaaaccggtcccggtgtcgcgcaggccgccgccgacgccgagggcaag atcgtcttcgtgttccccggccagggctcgcaatgggtcggcatgggccgcgagctgctg gagacgaacgcggtgttcgcggcgaagttcgccgaatgcgagcgcgccacttcgtccttt gtggacttctcgctgaccgaggcgctcgacgacgaggacgcgctcgcccggctcgacgtg gtccagccggtgctgtgggcggtgatggtgtcgctggccgcggtgtggcggtcctacggc gtgcacccctcggccgtggtcggccattcgcagggcgagatcgccgcggcgtgcgtcgcg ggtggactgtcccttgaggacggtgcgcgggtggtggcgctgcgcagcaaggcgctgctg gaggagctgttcgacaagggcgagctggcttcggtggcgctgcctgccgatcaggtcgcg gagcggctcaccgagttcgacgggcgggtcgcggtcgccgcgatcaacgggccgacgtcg acgatcatcgcgggcgacaccgaaccgctggcgcgcgtgttcgacgagtgggaggcggcc ggggtgcgcgtgcggcgcgttcccgcgtcgtgcccgtcgcacacccagcacgtcgaagtg ctgcgcgagcgcatgcgcaccgaactcggcccgatccggccccgcgagggcgaggtcgcg ttcttctccaccgcgaccggcacctggcaggacaccgccgggctggacgccgactactgg ttcgagaacatgcggcaggtggtgcgcttcgccgacgccacgaagtctttgttcggccag ggctaccggttcttcgtcgaggccagcgcgcacccggtgctcgcggtgagcgtgcaggag aacgtggaaagcctcgacggcgcttcagccgcggtcgtgggtaccttgcgccgcaacgaa ggcgggctcgcccggttcttcacctcgctcggccagctcttcgccgaaggggtcacgccg gactggagcgccgtgttcggagaaggcgcgcagcgggtcgagttgccgacctacgtcttc cagaacgagcgctactggcactcctcgaccaccgccgccggtgacgtcacctccgtggga ctcacctcggccgagcatccgctgctcggcgccggcgtcgatctgcccgacaccgacggg ttcctgttcaccgggcggctttccctgcagacgcacccgtggctggccgatcacgcggtc gcggacacggtgctggtgcccggtaccgcgttcgtcgagctggcgatcagggcgggcgac caggtcggctgccagaccgtcgaagagctgacgctgcacgcgccggtgatcctcgccgcg cagggcgcggtgcgcctgcaggtcgtggtgggcgcgccggacgagaccgggcgccggtcg ttgaccgtgcactcccgcgccgaggacgcgccgtcgaactcggcgtggacgcgcaacgcc agcggtttcctcgccgaagccgaaccggtgggcggattcgacctggccgcgtggccgccg ccgcaggccgagccggtcgaagacgccactgggctctacggccgcctcaccgaactgggc taccagtacgggcccgcgttccaggggctgaaggcggcgtggacgcgcggggacgaggtc ttcgccgaggtcgcgctgcccgaagaacaccacgccgacgccgccgggttcggcgtgcac cccgcgctgctcgacgcggcgctgcacgcgtgcagcttcggcgcgctggtcaagggtgac gagggcatgggcctgccgttcgcgtggacgggcgtgtccctttccgccgcgggcgccacc acggtgcgcgtccggatcacccccgccggttccgacgggatctcggtgcaggtcgccgac cagaccggcgcgccggtcgtctcggtcgaggcgatggtgctgcgcccggtttcggcggag cagctcgccgccgcgcgcgacaccgggcccgacgcgttgtaccagctcgactggaccgtc gtggagcccccgcgcgacgcgggcaccgaaggctgggtcgtgctcggcgaggaccggttc ggcctcggcgacttcctcacctaccccgatctcgccgcgctcatcgccgcggtggacgac ggcgcgccggtgcccgaggtcgtcatcgcgccggaaacggtgccactgagcggaaatccg gccgacgcggcgaggaccgcggccgcgaaggcgctcggcctcgcgcagacgtggctggcc gacgaccggttcgacgccgcgcgcctggtgctggtgaccagcggcgcggtggcggttgac gcggaatccgatgtcaccgatctggcttcggcttcggcgtggggcctgctgcgctccgcc gaatcggagaaccccgggcggttcgtgctcgcggacctcgacggccacgcggattcgccg cgcgcgctcgtcgccgcgctgaccaccgacgaacagcagctggccgtgcgcgaagggatc gtgcgcgcgccgaggctcgccagggccggtaccggttcgctgacgatcccggccgacacc cgcgcgtggcggctggaagtcagcgaacagggcacgctggcgaacctggcgctgcgggaa tgccccgaagcgctggatgccttggagccggggcagatccggatctccgtgcgcgcggcc gggatgaacttccgtgacgtggtggtggcgctcggcatggtgccggggcaggacatcatg ggcagcgagatcgcgggagtcgtcaccgaagtcggcgagggcgtgacggatctccagccc ggttcgaaggtgttcggcatcgtcgaccgcgctttcggcccgctcgcggtcgcctaccgc gaaaccgtgaccccgatcccggacggctggacgttcgagcaggccgcttcgaccccgatc gtgttcctcaccgcctactacgggctgatcgacctcggcgggttgcgggcgggcgaatcc gtgctggtgcactccgccgcgggcggtgtcgggatggccgcggtccagctggcccagcac ttcggggccgaggtcttcggcaccgcgagcgcgggcaagtgggacgcgctgcgctcgatg ggactcgacgacgagcacatcgcgtcctcgcgcgatctcggcttcgagcaggcgttcggc ggcgtggacgtggtgctgaactcgctgacccaggacttcgtcgacgcgtcgctgcggctg ctgtcggacggcggccggttcctggagatgggcaagaccgacaagcgcgacccggacgag gtcgccgcggcgcatcccggggtgcgctaccgcgcgttcgacctgatcggcgcctccgcc gaccggctgcaggaaatgctgcgggaactggtggtgctgttcgagcagggcgcgctgaag ccgttgcccgtgcggacctacgacgtgcgccgcgcacccgacgcgttccggttcctgagc caggccaagcacatcggcaagctcgcactgacgatgccgcgcgaactcgaccgcgacggc acggtcctgatcaccggcggcaccggcaccctcggcgggctggcggcgcgccggatgatc accgagcacggcatccggcacctgctgctgaccagccgccgcggcccggacgcccccggc gccgccgaactggccgcggagctgaccgacctcggcgccgaggtcaggatcgtcgcgtgc gacgtcgcggacttcgcggcgaccgaggcgctgctgtcctcgatcccggcggagcacccg ctgaccggagtgctgcacaccgcggccgcgctcgacgacggcgtcgtgtcgtcgctgact cgagagcgggtggacgcggtgatgcggcccaaggcggacgccgcgtggaacctgcacgag ctgaccaaggacctcgacctcgcgctgttcgtgctgtactcctcggccgcgtcggtgttc ggcgcttcgggtcaggggaactacgcggccgcgaacgcgttcctcgacgcgctcgcccag caccgccgcgccgccgggctgcccgcgcaatcgcttgcgtgggccatgtgggagcagcgc agcgagctgacccgccacctcggcgacgaccagatgcgcaagcgcagcaacgacgggttc ccgccgctgacctccgagcagggcatggcgctgctcgacgtggccgcgggtgtcgacgag gcgatgctggtgccgatccagatcgacaccgacgtggtgcgccgcaagatctccggtgcg gtgccgccgctgctgcgcgggctgatccgcgcgaccccgcggcgcgtcgtggaagccggg ccgacggtcaccgggatggcgggacggctttccgggctgtccgaaggcgaacagcacgcg ctcgtgctcgccgtggtccggtcgaacgtcgcttcggtgctgggacacgcttccgccgag tcgatcggcgcggaccgcgcgttcaaggaactgggcttcgactcgctcaccgcggtcgag ctgcgcaaccggctggccaccgccaccggcgtgcggctgcccgcgaccgcggtgttcgac cacccgtcgccggccgaactggccgagttcgtccgctccgaactgctcggcgtcaagctg gaggagaccgcgccggtggtttcggcgcacccggccaccgacgacgacccgatcgtgatc gtgggcatgggctgccgcttccccggcggcgtcgcctcaccggacgacctgtggaggctg gtggattccggcaccgacgcgatttcggagttcccgaccgaccgcggctgggacctcgac ggcatctacgacccggacccggacgtgccgaacacgacctactccaccgagggcgggttc atctacgacatcgcgggcttcgacgccgacttcttcggcatctccccgcgtgaagcgctc gcgatggacccgcagcagcggctgctgctggaaacctcttgggaggcactggaacaggcc gggatcgacccgtcctcactgcgcggttctcggaccggcgtgttcgtcggctcgtacggg atgggctacgggtggacgctcgaagacgtgcccgccgatctcgaaggcttcctgtcctcg gggcagagcaccagcatcatctccgggcgcgtcgcctacacgctcggcttgcagggcccc gcgatcaccgtggacgcggcgtgcgcttcgtcgctcgtcgcgttgcactgggcgagccag gcgctcgccgagcaggagtgctcgatggcactggtcgccggggtctcggtgatggtgtcg ccgggtgcgttcaccgagttcagccgcatgcgtgggctgtcgaagaccgggcgttccaag gctttcgccggtgccgcggacgggatgggctggggcgagggcatcggtgtgctcgtcgtc gagcggctgtccgacgcgcgccgcaacggccacgaggtgctcgccgtggtgcggggctcc gcggtcaactccgacggcgcgtccaacgggctgacctcgccgaacgggagggcgcagcag cgcgtcatccgccaggcactggcgagcgcgaacctcacctccgccgaggtcgacatggtg gaggcgcacggcaccggcaccacgctcggcgacccgatcgaggcgcaggccctgctggcg acctacggccaggaccggccgtccgacgagccgctgtggctcggttcgctgaagtcgaac atcgggcacacccaggccgccgccggggtcgccgggatcatcaagaccgtgcaggcgctg cgcaacggcgtgctcccgaagacactgcacgtggacgagccgaccccgcacgtcgactgg tccgcgggcgcggtgtccgtattggacgacgcacgagcgtggccggacaaggggcgcccg cgccgcgccggggtgtccgcgttcgggctgtccggcaccaactcgcacgtgatcctcgaa cacgagccggtgccggcggagccgtcgcccgaacccgcgccggtcgccggatcggtgccg tgggtgctttccggcaagacggccgaagcgctgcgcgcgcaggccgcccggctgcggtcc catgtggacgaacacgccgagctttccccggtggacgtcgcgttctcgctggcgaccacg cgcgcgtcgctggagaaccgggccgtggtgttcggcggggaccgcgacgagttcctgcgc gggctcgccgcggtcgccgacggcgaatccgtcgccggggtggtccagggcgcggccgag gccgaggggcagacggtgttcgtgttccccggccagggttcgcagtggaccgggatggcc gtggagctgctcgacaccagcgaggtgttcgcggagcggttcgccgagtgcgagcgcgcg ctgtcgtcctttgtggactggtcgctctcgtacgcggtgcgcgacgaggcactgctggag cgggtcgacgtcgtgcagcccgcgttgtgggcggtgatggtgtcgctcgccgcggtgtgg cggtcctacggtgtggagcccgccgcggtggtcgggcattcgcagggcgagatcgcggcg gcgtgtgtcgcgggtgcactgtcccttgaggacggtgcgcgcgtggtggcgttgcgcagc atcgcgatctccgacgagctggccggtaagggcggcatggtctcgatcgcactgcccgaa accgctgtggtcgagcggatcgcgcggttcggtgaccgggtcgcggtggccgcggtcaac gggcccggggtcaccgtgatcgccggtgaacccgaggcgctcgccgagatcctcgccgag tgcgaggaagcggagatccgggcgcgcaagatcgccgtggactacgcgtcgcacaccccg caggtggagtccatccgggaccgtctgctggaggtcctatccccgatccagccccgcgcg ggcgagatcgcgttcttctccacggtgaccgccgactggcaggacaccaccgggctcgac gccgagtactgggtggaaaacctgcgccgcacggtgaagttcgaacaggccacccgcggc ctgatcgagcacggctaccggttcttcgtcgaatccagcgcgcaccccgtgctgaccatc ggcgtccaggaaaccctcgaagccaccggcgccaccggcgcggtgctcggctcgctgcgc cgcgacgaaggcggcctcgaccggttccacacctcgctcgccgaggcctacgcggccggt gccgcggtggactggaccgcggcgttccccgagggcgcccggcgggtggccttgccgacc tacgccttccagcaccggaacttctggctggcaggcgagccggtccggcccgaggcgcac accgacgaggtcgaagcggtgttctgggacgcggtcgagcgcgaggacctcgaagagctg gcggccacgttggacgtggcggactcctcgctcggcgaactgctccccgcgctgtcgtcc tggcggcggcagcggcgtgagaagtccacagtggacaactggcggtaccggatccggtgg cagccggtcaccggggccaccgaagacgcgcggctctcgggcacctggctcgtggtcgtc gcggacggcgtcgagcacgaatgggtccccgcggccaccgcggcgctcgccgaggcgggt gcgcgcgtggccgaggtgcggctgagcgccgacgaccgcgaccgcgacgacctcgcgcgg cgactgcgcgaggcagcgggggaggagcccgtcgccggggtgctttccttgctgggcttg gacgagcggccccatccggagcacccggtgctgaccaccgggctgaccgcttcggtgctg ctggtccaggcgctcgccgaaacgggcctcggcgccaggctgtggttcgcgaccacgggc gcggtgtcggtcggccggtcggactcgctgaccgggctggcgcagtcgccggtctggggc ctcgcccgcagcgtcggcatggagtacgcggcgacctggggcggcgtggtcgatctgtcg gtttcctcggagggccgcgccacggcacggctcgtctcggtgctcgccgggctcgacgag gaccaggtcgcgctccgcgactccggcgtgttcgcgtgccgcctggcgcacgctccgctg cgcgagtccgcgaagaccaccgaatggcggccacgcggcaccgtgctggtcaccggcggc accggcgggctcggcgcgcacgccgcgcgctggctcgccgtgcacggcgccgaacacctg gtgctgaccagccgccgcggccgcgccgccgaaggcgccgccgagctggaagcggaactg accgggctcggcgctcaagtcaccatcgcctcgtgcgacgccgccgaccgggacgcgctc gcggacctgctcgcctcgctccccggtgagctgaccgcggtggtgcacaccgccggcgtg ctcgccgacggtgtgctgtcgtcgatggacctgccgcggctggccgagacgatgtacccc aaggtgaccgcggtgtggaacctgcacgagctgacgcgggacctcccgctcgacgccttc gtgctgtactcgtcgttctcgagcacgctcggcagcgcggggcaggcgaactactccgcc gccaacgccttcgtcgacgccttcgcccattaccgcagggaactgggcctgcccgcgacg gcgatcgcctggggcgcgtgggcaggttccggtctcgcggtggcctcggacgtgcgcaag gacctgctcagcgggatcggggtgccgttcatggaccccgccaccgcgatgctgggcttc cagcaggcggtcgaagcggacgagacgcatctcgccgtgatcgacatcgactggccggtg ttcatgcccgcgctcgccgaggtgcggccgcggccgttgttcgacgcgcttccgcaagcg cggcaagcacttcagcccgtggccgctgccgtggccgaggccgcgggtccgccgctcgcc gggcggctggccgggctcaccggtgccgagcgggaacgggagttgcttgacctggtgcgc ggccaggtcgcggtcgtgctcgcgcactcctcggccgaggacgtcagcaggcagcggccg ttccgcgatctcgggttcgactcgctgaccgcgctcgagttccgcaaccgcatcgccgcg gccaccgggctgagcctgccgtcgaccctgatcttcgactaccccacgccgaacgcgctg tgcgacttcctgctcgcggagctggtcggcgaggacgccgcgcaggcggcgcaggtcgag ctcgccgcggcgagcaccgacgagcccatcgcgatcatcgggatgagctgccggttcccc ggcggcgtcggctcgccggaggacctgtggcggctggtggacgccgggatcgacgccatg tcggccttccctgccgaccgcggctgggaatccgagacgctctacagcgacgacccggac agccccgggaccacgtatgcgacccaaggcgcgttcctcgacgacgcgggcggtttcgac ccggcgttcttcgacatctcgccgcgcgaggcgctggtgatggacccgcagcagcggttc ctgctggaggcgtcgtgggaggccttcgaacgggcggggatcgacccgacctcggtgcgg ggcagccgcaccggcgtgttcgcgggcagcaacgggcaggactaccgctacagcatcggg gactccgccgaagacagcgagggctacctgatgaccggcaacgcggcgagcgtggtgtcg ggccgggtctcctacaccttcgggctggaagggcccgcggtcaccgtggacacggcgtgc tcggcctcgctcgtggcgctgcacctcgcgtgccagtcgctgcggcagggcgagtgcacg atggcgctcgccagcggtgtcacggtgatgacgaccccgggcgggttcgtcgagttctcg cggcagcgggggctggcttccgacggccggtgcaaggcgttcgcggcggccgcggacggc accggctggggtgaaggtgtcggcgtgctgctcgtcgagcggctctccgatgcccggcgc aacgggcaccaggtgctggccgtggtccggggctccgcgatcaaccaggacggcgcgtcg aacgggttgaccgcgccgaacggtccttcgcagcagcgggtgatccggcaggcgctggcc agcgcgcgcctggcaccgtccgaagtggacgctgtggaagcgcacggcacgggcaccgcg ctcggtgatccgatcgaggcgcaggcgttgctggcgacctacggccaggatcgtgagcgt ccgttgtggctgggttcggtgaagtcgaacatcgggcacacgcaggcggcggcgggtgtg gccggggtgatcaagatggtcgaggcgatgcgccacggcgtgctgccgaggacgctgcac gtcgacgagccgaccccgcacgtggactggacgaccggcgcggtctcgctgctcaccgat acgacgccgtggccggagagcggcggcccgcgccgtgccgggatctcctccttcggcatc agcggcaccaacgcgcacgtcatcatcgagcaggcaccaccggtgccggaggtgccggag cgcacgccggtgcaccgcgtgctgccgtggcccctggcgggcaagaccgagaaggcgctg cgggcgcaggcggccaggcttttgtccacagtggacgacttcgccgatctcgacgtggcc tactcgctggccacctcccgcgcggcgctggagcaccgcgcggtggtggtcgcggccgac cgcgacgagttccggcgcgggctgaccgcgctcgccgagggcgactcggtgtccactgtg gtcaccggagacgcctacggcgacacgaggtcggcggtgctgttctccggccagggttcg cagcgcgcgggtatgggcaaggagctatatggggagttccccgttttcgcggacgcgctc gacgccgtgtgtgcggaactggacaggtccctggatcgtccgctgaaggagctgatgttc gccgaggcgggctcggaggacgcggcgctgctggaccagacccagtacacgcaggtgtcc ctgttcgcactcgaagtcgcgttgtaccggctcgtcgagtcgtggggcatccgcccggac ttcgttgccgggcattcgatcggtgaactcaccgccgcgcacgtcgcgggtgtgctgtcc cttgaggacgccgcggcactggtggtggcgcggggccggttgatgcaggccctgccttcc ggcggcgcgatgctttccgtgcaggcgagcgaggacgagatcgcgccactggtggtggga ctcgaggacaaggtgtcgatcgcggcggtcaacggcccggcttcggtcgtgatcgcgggc gacgaggacgtgatcgccgggttcgagtcggcgtgggagtggaagacgaagcggctcacc gtgtcgcacgcgttccactcgccgcacatggagccgatgctggcggagttccgcgccatc gcccggaacctgagcttccaggcgccgaagatccccgtggtgtccactgtgcccggtggg gtcggggacgtgaccgaccccgagtactgggtgcggcacgtgcgcgaagcggtgcgcttc gccgacgccgtgcggcgcctggaagaccagggcgtctcggcgttcctggaactgggcccc gacggcgtgctgaccggcatggcgcgggattgtcttgccggggaacgggtttcgctggtg acggcgctgcggcgcgaccgcgacgaggtgcgcacgatcaccgccgcggtggccgggctc cacgtccgcggcgtgccggtggactggacggcgctgttcgccggaaccggcgcgcgcacc gtcgacctgcccacctacgccttccagcaccaggtgttctggccgaagtacgtgccgggc gcgaccgcgaagggcgatgccggcagcctcggcctcgcctcaccggatcacccgctgctc ggcgcggtggtggaactggccggcgaggacgggttcctgttcaccggcaggctttcccgg ccgacactgccgtggctcggcgacgacgccgacgggcccgacgctgcggtgccgactgtg tcttcctcggtgttcctcgaactcgcggtgcgcgcgggcgaccaggtcggctgcggccac ctggcggagctgaccctgcgggagccgctggtgctgcccgagcgcggcggggtgcgcctg caggtcaccgtcgcggcaggggacgagtcggggcggcgggcactggaagtgttctcccgc aacgatgacgaggacggcgcgtggtcctgccacgccagcggcgtactggccccggcggaa ccgatcgccgcggccgaactcgcggaatggccgcccgcgaaggccaccccggccccggag gaagcgttcggcgccgtccgtgccgtgtggacgaccgaggacgcgctgttcgcggagatc gtcctccccgaggagcaccgcgacgacgcgttcgctctgcacccggcgctcctggaggcg ctgcgccccggcaggctgatcggggatgagtcgctggttccccagacgtggcaagggttc cggctgcacgccgtcggcgcgtcgtcggtgcgtgcgcggatctcgcgcgcgggttccggc gccgtgtcgatcgacctcgccgacgagacgggcgcgccggtggccacggtcgcctcgctg accttgcgggaagcgcccgcggaccggttcggcgcgctgcgcggcgggcggaacgggtcg ctgtaccgcgtcgactggacggaggtgcccggccgcgactgggcgccgggcgcgccgctg gccgtactcggcgacgcgatcgacggcgtgaccggtgccgagtcctatgtggaccttgcc tcgctcgccgccgccgtcgacgcgggtgcgccgagtcccgaggccgtgctcgtccgggtc gccgacccgaccggggccgtcgatgccaccggcatcgcggccggggtcaggcaggtcacc ggccgcgtgctggcgctcctgcagcagtggctggccgacgaccggttcgccgcgtcgaag ctggtgctcgtcaccggcggcgcggtcgcggcggtccctgccgattccccgaacctggtc accgcgccggtgtggggcctggtcaaggcggcgcaggcggaacaccccgaccggctcgcg ctggtcgacgtgcccggcggggccgaatggccgcgcgtgctcggcgcggtgttcgagtcc ggtgagcaccagctcgccgtccgggacggggcgctgcgcgcgccgcgcctcgtgcgggag caggtgaccgtcgacgtcgacactggcaccgccggcgccttcgacccggagggcaccgtg ctggtcaccggcgcgaccggcgggctcggcgcgctgttcgcccggcacctggtcaccgag tacggggcgaggcacctggtgctggccagccggtccggccgggccgccgagggcgcggcc gagctggagaaggacctggccgaactcggtgcggaggtttcgctcgtcgcctgcgacgtc gcggatcggacggcactggccgggctgctcgacgggatcggctccgcgcacccgttgacc gccgtggtgcacaccgccggtgtgctcgacgacggcgtcaccggcgcgctcaccccggag cggctcgacaccgtcctgcggccgaaggtggacgcggcgctgaacctgcacgagctgacc gaggacctcaagctcagcgagttcgtgctgttctcggcggcgggcagcgtgctcggcgcc gcggggcagggcaactacggcgcggcgaacaccttcctcgacgcgctggcccagcaccgc agggcgcgcggcatggtcggcagggcgctggcgtggggcctgtgggcgcagaccgccggg atggcgggcgagctcaccgccgggcagctcgccaggatggaccgcggcggggtcaagccg ctgtcggacgagcaggggctcgccctgttcgacctcgctcgcgaggcgggcgaggcggcg ctgctgccggtgcggctcgacctcaccgcgttgcgcgcggagctcggtggctcggtgccc ccgctgctgcgcgggctgctcggcgacggaaccgccaggcctgccgcgggcaaagcagct gctcagccggatctgtccgcggagctggcgggcctgtccgaagccgagcggcggcgcgcc gtgctgcggctggtccgcacgcaggtcgcgaccgtcctcggccacgacgaccagtccgcg gtcgaggtcaaccggggcttcctggaaatgggcttcgactcgctgaccgcggtggacctc cgcaaccggctcaccgcgctgaccgggcggccgctcccggcgaccctgctgttcgactac ccgtcaccgggggagctcgccgagcacctcaccgcggagctcgggcaggtcgacggcggc gacggcggctcgctgcacgccgatctcgaacggctcgaacggtccgtctccgcggccgcg gtcgacgacgggcagcgtggggagatcgcgaccaggctgcgcgcgctgctcgctcagctc acgccgggttcggaagaggtctcggtggcggatcagctcgacgcggccaccgatgacgag atcttcgaattcatcgacaacaacttggatgcctag

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