KEGG   Amycolatopsis sp. CA-230715: HUW46_08990
Entry
HUW46_08990       CDS       T10444                                 
Symbol
cysG_2
Name
(GenBank) Siroheme synthase
  KO
K02302  uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:2.1.1.107 1.3.1.76 4.99.1.4]
Organism
amyz  Amycolatopsis sp. CA-230715
Pathway
amyz00860  Porphyrin metabolism
amyz01100  Metabolic pathways
amyz01110  Biosynthesis of secondary metabolites
amyz01120  Microbial metabolism in diverse environments
amyz01240  Biosynthesis of cofactors
Module
amyz_M00846  Siroheme biosynthesis, glutamyl-tRNA => siroheme
Brite
KEGG Orthology (KO) [BR:amyz00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00860 Porphyrin metabolism
    HUW46_08990 (cysG_2)
Enzymes [BR:amyz01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.76  precorrin-2 dehydrogenase
     HUW46_08990 (cysG_2)
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.107  uroporphyrinogen-III C-methyltransferase
     HUW46_08990 (cysG_2)
 4. Lyases
  4.99  Other lyases
   4.99.1  Sole sub-subclass for lyases that do not belong in the other subclasses
    4.99.1.4  sirohydrochlorin ferrochelatase
     HUW46_08990 (cysG_2)
SSDB
Motif
Pfam: TP_methylase NAD_binding_7 2-Hacid_dh_C
Other DBs
NCBI-ProteinID: QWF85535
UniProt: A0A975N858
LinkDB
Position
complement(9814464..9815690)
AA seq 408 aa
MLMRMPEEDQHYLVGLDLAGRRVVVVGGGTVAQRRVPRLLGAGAVVEVISPSCTPSVQAM
ADAGELTWTQREYAEGDLADAWYALACTANPEVNAAVCAEAERVRIFCVRADSGLDGSAV
TAAVGRHDGLLVGVLSGGHPLRSAAVRDRIVEALHTGAVEDGETRRGEGLPGVALVGGGP
GDPELITVRGRRLLARADVVVADRLAPRELLDDLPPEVEVVDAAKIPYGRAASQDVINAT
IIEHAKAGRFVVRLKGGDPYLFGRGFEEVLACVEAGVPVVTVPGITSAFAVPAAADVPVT
HRGVAHEVVVVSGHLPPGHEQSLVDWQALGRMRGTIVLMMGVERLAQFAETLLAHGRPPE
TPVAIVEDGTMRTQRALRSTLDSVASAAAEAGVRPPAVIVIGPVAALA
NT seq 1227 nt   +upstreamnt  +downstreamnt
atgctgatgcgcatgcccgaagaagaccagcactacctcgtcggactcgatctcgcaggc
cgccgcgtcgtcgtggtcggtggcggcacggtggcgcagcgccgggtcccgcgcctgctc
ggcgcgggcgccgtggtcgaagtgatctccccgtcgtgcacgccgtccgtgcaggcgatg
gccgacgccggtgagctgacctggacccagcgcgagtacgccgagggtgatctcgcggac
gcgtggtacgcgctggcctgcacggcgaaccccgaggtgaacgccgcggtgtgcgccgaa
gccgagcgcgtgcggatcttctgcgtccgcgccgattccggtctcgacgggagcgccgtg
accgccgcggtcgggcgccacgacgggctgctggtcggcgtgctttccggcgggcatccg
ctgcggtcggccgcggtgcgggaccgcatcgtcgaggcgttgcacaccggcgcggtcgag
gacggggaaacccgccgcggcgaaggacttccgggcgtggccctggtcggcggcggtccc
ggcgacccggagctgatcacggtgcgcggccgccgcctgctcgcccgcgccgacgtggtg
gtcgccgaccggctggccccgcgcgagctgctcgacgacctgccgcccgaggtggaagtc
gtcgacgcggcgaagatcccgtacggcagggcggcctcgcaggacgtgatcaacgccacg
atcatcgagcacgccaaggcgggccggttcgtggtgcgcctcaagggcggcgacccgtac
ctgttcggccgcgggttcgaagaggtgctcgcctgcgtcgaagcgggcgtcccggtggtg
acggttcccgggatcaccagcgccttcgcggtgcccgcggcggcggacgtgccggtgacc
caccgcggcgtcgcgcacgaggtggtcgtggtctcgggccacctgccgccaggccacgaa
cagtcccttgtggactggcaggcgctgggcaggatgcgcggcaccatcgtgctcatgatg
ggcgtcgaacggctcgcgcagttcgcggaaaccctgctggcgcacggcaggccgccggaa
accccggtggcgatcgtcgaggacggcaccatgcggacccagcgcgcgctgcggtccact
ttggactcggtggcgtcggcggcggccgaagccggggtgcgcccgcccgcggtgatcgtg
atcggaccggtcgccgcgctggcctga

DBGET integrated database retrieval system