Amycolatopsis mediterranei RB: B737_2023
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Entry
B737_2023 CDS
T02804
Symbol
gcpE
Name
(GenBank) 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase
KO
K03526
(E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase [EC:
1.17.7.1
1.17.7.3
]
Organism
amz
Amycolatopsis mediterranei RB
Pathway
amz00900
Terpenoid backbone biosynthesis
amz01100
Metabolic pathways
amz01110
Biosynthesis of secondary metabolites
Module
amz_M00096
C5 isoprenoid biosynthesis, non-mevalonate pathway
Brite
KEGG Orthology (KO) [BR:
amz00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
00900 Terpenoid backbone biosynthesis
B737_2023 (gcpE)
Enzymes [BR:
amz01000
]
1. Oxidoreductases
1.17 Acting on CH or CH2 groups
1.17.7 With an iron-sulfur protein as acceptor
1.17.7.1 (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (ferredoxin)
B737_2023 (gcpE)
1.17.7.3 (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (flavodoxin)
B737_2023 (gcpE)
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Motif
Pfam:
GcpE
Asp_Glu_race
Zn_ribbon_9
Motif
Other DBs
NCBI-ProteinID:
AGT82687
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Position
2190928..2192097
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AA seq
389 aa
AA seq
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MGTLEAVTVALGMPALPPPVLSERRKTRQLQVGSVGVGSDHPISVQSMTTTLTSDVNATL
QQIAELTAAGCDIVRVACPSADDAEALPAIAKKSQIPVIADIHFQPKYVFAAIEAGCAAV
RVNPGNIRKFDDQVKEIAQAAKDHGTPIRIGVNAGSLDKRIMDKYGKATPEALAESALWE
ASLFAEHDFHDIKISVKHNDPVVMVRAYELLAEQCDYPLHLGVTEAGPAFQGTIKSAVAF
GALLRQGIGDTIRVSLSAPPVEEVKVGIQILQSLNLKQRKLEIVSCPSCGRAQVDVYTLA
EQVTAGLEGMEIPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVKGEVIKTVPEHAI
VETLIEEAMRIAEEAGESLGEGAPVVTAG
NT seq
1170 nt
NT seq
+upstream
nt +downstream
nt
gtgggtacgctggaagccgtgaccgtcgcactcggtatgcccgccctgcccccgcccgtc
ctgtccgagcgccgcaagactcgccagctccaggtgggttcggtcggcgtcggcagcgac
cacccgatctccgtccagtcgatgacgacgaccctcacctccgacgtcaacgccaccctg
cagcagatcgccgagctgaccgccgcgggctgcgacatcgtccgcgtggcgtgcccgtcg
gccgacgacgccgaggcgctgccggcgatcgcgaagaagtcgcagatcccggtgatcgcc
gacatccacttccagcccaagtacgtcttcgcggcgatcgaggccggctgcgccgccgtg
cgcgtgaacccgggcaacatccggaagttcgacgaccaggtcaaggagatcgcgcaggcc
gcgaaggaccacggcacgccgatccggatcggcgtcaacgcgggttcgctcgacaagcgg
atcatggacaagtacggcaaggcgacgccggaggcgctggccgagtcggcgctgtgggag
gcgtcgctgttcgccgagcacgacttccacgacatcaagatctcggtgaagcacaacgac
ccggtggtcatggtgcgcgcctacgagctgctcgccgagcagtgcgactacccgctgcac
ctcggcgtcaccgaggccgggccggcgttccagggcacgatcaagtcggccgtcgcgttc
ggcgcgctgctgcgccagggcatcggcgacacgatccgcgtctcgctgtccgcgccgccg
gtcgaagaggtcaaggtcggcatccagatcctgcagtcgctgaacctcaagcagcgcaag
ctggaaatcgtgtcgtgcccgtcgtgcgggcgcgcgcaggtggacgtctacacgctggcc
gagcaggtcacggccgggctcgagggcatggagatcccgctgcgcgtcgccgtcatgggc
tgcgtcgtgaacggcccgggtgaggcccgcgaggccgacctgggtgtggcgtcgggcaac
ggcaagggccagatcttcgtcaagggcgaggtcatcaagaccgtgccggagcacgcgatc
gtcgagacgctcatcgaagaggccatgcgcatcgccgaagaggcgggcgagtccttgggt
gagggcgcgccggtggtcaccgctggctga
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